Drosophila melanogaster

7 known processes

Rpn5 (Dmel_CG1100)

CG1100 gene product from transcript CG1100-RA

(Aliases: p55,Dmel\CG1100,CG1100)

Rpn5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
proteolysis GO:0006508 192 0.693
modification dependent macromolecule catabolic process GO:0043632 79 0.590
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.476
modification dependent protein catabolic process GO:0019941 78 0.377
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.342
ubiquitin dependent protein catabolic process GO:0006511 78 0.274
er associated ubiquitin dependent protein catabolic process GO:0030433 3 0.268
cellular catabolic process GO:0044248 372 0.239
macromolecule catabolic process GO:0009057 161 0.232
multicellular organismal aging GO:0010259 140 0.187
cellular protein catabolic process GO:0044257 83 0.185
aging GO:0007568 143 0.176
proteasomal protein catabolic process GO:0010498 59 0.132
protein catabolic process GO:0030163 101 0.130
cellular response to dna damage stimulus GO:0006974 223 0.125
organic substance catabolic process GO:1901575 308 0.123
larval development GO:0002164 104 0.113
cellular macromolecule catabolic process GO:0044265 136 0.104
catabolic process GO:0009056 409 0.092
regulation of cellular protein metabolic process GO:0032268 243 0.077
endocytosis GO:0006897 310 0.077
regulation of endopeptidase activity GO:0052548 36 0.076
embryo development ending in birth or egg hatching GO:0009792 152 0.075
Worm
death GO:0016265 284 0.074
apoptotic process GO:0006915 159 0.074
cellular protein modification process GO:0006464 438 0.068
Yeast
protein modification by small protein removal GO:0070646 28 0.059
Yeast
regulation of proteolysis GO:0030162 87 0.059
regulation of cellular component biogenesis GO:0044087 201 0.057
proteasome assembly GO:0043248 2 0.056
protein deubiquitination GO:0016579 17 0.052
organelle assembly GO:0070925 198 0.051
regulation of gene expression epigenetic GO:0040029 128 0.049
vesicle mediated transport GO:0016192 381 0.045
regulation of vesicle mediated transport GO:0060627 59 0.045
determination of adult lifespan GO:0008340 137 0.043
secretion GO:0046903 109 0.042
body morphogenesis GO:0010171 2 0.041
regulation of proteasomal ubiquitin dependent protein catabolic process GO:0032434 37 0.040
cell proliferation GO:0008283 299 0.040
gland development GO:0048732 191 0.039
cell death GO:0008219 279 0.039
regulation of developmental growth GO:0048638 174 0.038
regulation of peptidase activity GO:0052547 39 0.038
protein modification process GO:0036211 438 0.037
Yeast
positive regulation of cellular biosynthetic process GO:0031328 316 0.037
positive regulation of cellular component organization GO:0051130 156 0.035
organophosphate metabolic process GO:0019637 195 0.033
salivary gland cell autophagic cell death GO:0035071 83 0.031
regulation of endocytosis GO:0030100 37 0.031
negative regulation of gene expression GO:0010629 387 0.031
organic cyclic compound catabolic process GO:1901361 168 0.030
intracellular signal transduction GO:0035556 300 0.029
positive regulation of cellular protein metabolic process GO:0032270 118 0.028
regulation of multicellular organismal development GO:2000026 414 0.028
regulation of localization GO:0032879 275 0.026
brain development GO:0007420 120 0.026
response to external biotic stimulus GO:0043207 293 0.025
muscle structure development GO:0061061 224 0.025
dna metabolic process GO:0006259 227 0.024
defense response to bacterium GO:0042742 178 0.024
protein dna complex subunit organization GO:0071824 86 0.023
endomembrane system organization GO:0010256 119 0.023
regulation of synapse organization GO:0050807 110 0.023
regulation of synapse structure and activity GO:0050803 128 0.023
mitotic spindle organization GO:0007052 220 0.023
eye development GO:0001654 323 0.022
positive regulation of growth GO:0045927 75 0.022
spindle elongation GO:0051231 83 0.021
response to biotic stimulus GO:0009607 294 0.021
cellular component assembly involved in morphogenesis GO:0010927 151 0.021
regulation of protein metabolic process GO:0051246 256 0.021
negative regulation of developmental process GO:0051093 201 0.021
positive regulation of proteolysis GO:0045862 52 0.020
head development GO:0060322 135 0.020
aromatic compound catabolic process GO:0019439 166 0.020
positive regulation of developmental process GO:0051094 143 0.019
small molecule metabolic process GO:0044281 305 0.019
purine nucleoside triphosphate catabolic process GO:0009146 108 0.019
regulation of response to external stimulus GO:0032101 115 0.019
programmed cell death GO:0012501 257 0.018
macromolecular complex assembly GO:0065003 256 0.018
phagocytosis GO:0006909 215 0.018
transcription initiation from rna polymerase ii promoter GO:0006367 25 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.017
regulation of transport GO:0051049 181 0.017
regulation of cytoplasmic transport GO:1903649 47 0.017
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.017
protein ubiquitination GO:0016567 70 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
skeletal muscle fiber development GO:0048741 3 0.016
developmental growth GO:0048589 280 0.016
eye morphogenesis GO:0048592 260 0.016
reproductive system development GO:0061458 74 0.016
apoptotic signaling pathway GO:0097190 27 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
cellular homeostasis GO:0019725 80 0.016
mitotic cell cycle checkpoint GO:0007093 88 0.016
posttranscriptional regulation of gene expression GO:0010608 145 0.016
protein complex assembly GO:0006461 200 0.015
positive regulation of cellular component biogenesis GO:0044089 80 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
regulation of protein localization GO:0032880 76 0.015
gland morphogenesis GO:0022612 145 0.014
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.014
protein transport GO:0015031 155 0.014
secretion by cell GO:0032940 101 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
regulation of immune system process GO:0002682 176 0.013
phosphorylation GO:0016310 294 0.013
regulation of response to stress GO:0080134 200 0.013
spindle organization GO:0007051 253 0.013
response to abiotic stimulus GO:0009628 341 0.013
cell motility GO:0048870 251 0.013
negative regulation of signaling GO:0023057 219 0.013
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.013
regulation of cell cycle process GO:0010564 181 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
protein secretion GO:0009306 45 0.013
glycosyl compound catabolic process GO:1901658 112 0.012
camera type eye morphogenesis GO:0048593 2 0.012
central nervous system development GO:0007417 201 0.012
regulation of protein modification process GO:0031399 112 0.012
regulation of hydrolase activity GO:0051336 97 0.012
camera type eye development GO:0043010 4 0.012
regulation of molecular function GO:0065009 217 0.012
positive regulation of cell death GO:0010942 69 0.012
response to drug GO:0042493 17 0.012
negative regulation of signal transduction GO:0009968 206 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
cell division GO:0051301 248 0.012
single organism catabolic process GO:0044712 228 0.012
response to lipopolysaccharide GO:0032496 4 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
regulation of cellular protein catabolic process GO:1903362 44 0.011
negative regulation of cell communication GO:0010648 223 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
mitotic nuclear division GO:0007067 213 0.011
regulation of proteasomal protein catabolic process GO:0061136 39 0.011
protein methylation GO:0006479 43 0.011
positive regulation of transcription factor import into nucleus GO:0042993 19 0.011
regulation of cell cycle GO:0051726 291 0.011
positive regulation of endopeptidase activity GO:0010950 26 0.011
positive regulation of peptidase activity GO:0010952 29 0.011
immune effector process GO:0002252 98 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
negative regulation of cell death GO:0060548 81 0.011
regulation of cell development GO:0060284 215 0.011
regulation of apoptotic process GO:0042981 130 0.011
organonitrogen compound metabolic process GO:1901564 318 0.011
regulation of cell death GO:0010941 173 0.011
macromolecular complex disassembly GO:0032984 37 0.011
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.011
developmental programmed cell death GO:0010623 138 0.011
regulation of rna polymerase ii transcriptional preinitiation complex assembly GO:0045898 1 0.010
regulation of cell differentiation GO:0045595 302 0.010
regulation of growth GO:0040008 233 0.010
mitotic dna integrity checkpoint GO:0044774 75 0.010
regulation of catalytic activity GO:0050790 185 0.010
positive regulation of molecular function GO:0044093 136 0.010
protein localization GO:0008104 284 0.010
establishment of protein localization GO:0045184 163 0.010
negative regulation of nucleoside metabolic process GO:0045978 1 0.010
negative regulation of cellular protein metabolic process GO:0032269 85 0.010

Rpn5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.032
disease of cellular proliferation DOID:14566 0 0.012
musculoskeletal system disease DOID:17 0 0.010