Drosophila melanogaster

26 known processes

SIFR (Dmel_CG10823)

SIFamide receptor

(Aliases: DrmSIFR,anon-WO0170980.43,anon-WO0170980.44,Dmel\CG10823,SIFa-R,SIF-R,CG10823)

SIFR biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
g protein coupled receptor signaling pathway GO:0007186 136 0.116
male mating behavior GO:0060179 70 0.108
multicellular organismal reproductive behavior GO:0033057 110 0.102
multi multicellular organism process GO:0044706 123 0.097
multi organism behavior GO:0051705 175 0.093
organonitrogen compound metabolic process GO:1901564 318 0.075
chromosome organization GO:0051276 360 0.069
mating behavior GO:0007617 106 0.067
reproductive behavior GO:0019098 122 0.066
carbohydrate derivative metabolic process GO:1901135 217 0.059
morphogenesis of a polarized epithelium GO:0001738 93 0.058
response to organic substance GO:0010033 284 0.055
protein complex assembly GO:0006461 200 0.055
chromatin organization GO:0006325 207 0.054
response to bacterium GO:0009617 198 0.054
appendage morphogenesis GO:0035107 397 0.053
chromatin assembly or disassembly GO:0006333 52 0.053
response to abiotic stimulus GO:0009628 341 0.051
male courtship behavior GO:0008049 63 0.050
protein complex biogenesis GO:0070271 201 0.050
detection of stimulus GO:0051606 156 0.049
small molecule metabolic process GO:0044281 305 0.047
response to endogenous stimulus GO:0009719 119 0.046
mating GO:0007618 120 0.046
phosphorylation GO:0016310 294 0.046
courtship behavior GO:0007619 68 0.046
appendage development GO:0048736 401 0.045
cellular amine metabolic process GO:0044106 12 0.045
nucleotide metabolic process GO:0009117 161 0.044
negative regulation of response to stimulus GO:0048585 258 0.044
macromolecular complex assembly GO:0065003 256 0.044
establishment or maintenance of cell polarity GO:0007163 167 0.043
response to oxygen containing compound GO:1901700 200 0.043
multicellular organismal aging GO:0010259 140 0.043
catabolic process GO:0009056 409 0.043
imaginal disc derived appendage development GO:0048737 399 0.042
response to other organism GO:0051707 293 0.041
rhythmic process GO:0048511 106 0.041
circadian rhythm GO:0007623 105 0.041
regulation of phosphorus metabolic process GO:0051174 210 0.041
organonitrogen compound biosynthetic process GO:1901566 117 0.040
negative regulation of cellular metabolic process GO:0031324 382 0.040
forebrain development GO:0030900 2 0.040
response to external biotic stimulus GO:0043207 293 0.040
phenol containing compound metabolic process GO:0018958 57 0.040
defense response to other organism GO:0098542 225 0.039
response to nitrogen compound GO:1901698 90 0.039
response to temperature stimulus GO:0009266 106 0.039
ribonucleotide metabolic process GO:0009259 145 0.039
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
dna metabolic process GO:0006259 227 0.039
positive regulation of cellular biosynthetic process GO:0031328 316 0.039
centrosome cycle GO:0007098 137 0.039
response to biotic stimulus GO:0009607 294 0.039
melanin metabolic process GO:0006582 47 0.038
establishment of localization in cell GO:0051649 402 0.038
dna conformation change GO:0071103 105 0.038
centrosome organization GO:0051297 163 0.038
vesicle mediated transport GO:0016192 381 0.037
protein modification process GO:0036211 438 0.037
cellular protein modification process GO:0006464 438 0.037
imaginal disc derived appendage morphogenesis GO:0035114 395 0.037
microtubule organizing center organization GO:0031023 168 0.037
positive regulation of response to stimulus GO:0048584 323 0.036
immune response GO:0006955 246 0.036
dna packaging GO:0006323 91 0.036
organic hydroxy compound metabolic process GO:1901615 83 0.036
morphogenesis of an epithelium GO:0002009 276 0.036
gland development GO:0048732 191 0.035
compound eye development GO:0048749 307 0.035
organophosphate metabolic process GO:0019637 195 0.035
cellular protein localization GO:0034613 160 0.034
death GO:0016265 284 0.034
multi organism reproductive behavior GO:0044705 121 0.034
ribose phosphate metabolic process GO:0019693 145 0.034
regulation of localization GO:0032879 275 0.034
endocytosis GO:0006897 310 0.033
regulation of response to stress GO:0080134 200 0.033
immune system process GO:0002376 347 0.033
chromatin assembly GO:0031497 48 0.033
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
camera type eye development GO:0043010 4 0.032
cell death GO:0008219 279 0.032
tissue morphogenesis GO:0048729 297 0.032
innate immune response GO:0045087 144 0.032
positive regulation of phosphorus metabolic process GO:0010562 139 0.031
eye development GO:0001654 323 0.031
pigment metabolic process GO:0042440 84 0.031
actin cytoskeleton organization GO:0030036 206 0.031
defense response GO:0006952 300 0.031
homeostatic process GO:0042592 199 0.030
amine metabolic process GO:0009308 12 0.030
wing disc morphogenesis GO:0007472 344 0.030
determination of adult lifespan GO:0008340 137 0.029
post embryonic appendage morphogenesis GO:0035120 385 0.029
intracellular signal transduction GO:0035556 300 0.029
cellular catabolic process GO:0044248 372 0.029
single organism behavior GO:0044708 391 0.029
oxoacid metabolic process GO:0043436 103 0.029
actin filament based process GO:0030029 220 0.029
positive regulation of signaling GO:0023056 243 0.029
organic substance catabolic process GO:1901575 308 0.028
regulation of protein metabolic process GO:0051246 256 0.028
regulation of phosphorylation GO:0042325 147 0.028
cellular amino acid metabolic process GO:0006520 61 0.028
detection of abiotic stimulus GO:0009582 66 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
organic substance transport GO:0071702 257 0.027
single organism biosynthetic process GO:0044711 206 0.027
immune response regulating signaling pathway GO:0002764 2 0.027
protein localization GO:0008104 284 0.027
regulation of cell death GO:0010941 173 0.027
localization of cell GO:0051674 257 0.027
programmed cell death GO:0012501 257 0.026
protein dna complex subunit organization GO:0071824 86 0.026
regulation of immune response GO:0050776 118 0.026
imaginal disc derived wing morphogenesis GO:0007476 337 0.026
positive regulation of cell communication GO:0010647 250 0.026
positive regulation of signal transduction GO:0009967 223 0.025
eye morphogenesis GO:0048592 260 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
leg disc morphogenesis GO:0007478 80 0.025
regulation of response to external stimulus GO:0032101 115 0.025
phagocytosis GO:0006909 215 0.025
chemosensory behavior GO:0007635 106 0.025
establishment of tissue polarity GO:0007164 87 0.025
neuropeptide signaling pathway GO:0007218 45 0.025
regulation of multi organism process GO:0043900 131 0.025
defense response to bacterium GO:0042742 178 0.025
purine ribonucleotide metabolic process GO:0009150 145 0.024
sensory organ morphogenesis GO:0090596 260 0.024
negative regulation of biosynthetic process GO:0009890 277 0.024
cellular macromolecule localization GO:0070727 220 0.024
carbohydrate derivative biosynthetic process GO:1901137 85 0.024
single organism catabolic process GO:0044712 228 0.024
cellular macromolecular complex assembly GO:0034622 153 0.024
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
olfactory behavior GO:0042048 97 0.024
developmental growth GO:0048589 280 0.024
regulation of molecular function GO:0065009 217 0.023
organonitrogen compound catabolic process GO:1901565 128 0.023
cellular modified amino acid metabolic process GO:0006575 45 0.023
compound eye morphogenesis GO:0001745 249 0.023
rhythmic behavior GO:0007622 76 0.023
negative regulation of cellular biosynthetic process GO:0031327 277 0.023
negative regulation of transcription dna templated GO:0045892 237 0.023
kidney development GO:0001822 3 0.023
enzyme linked receptor protein signaling pathway GO:0007167 179 0.023
cellular response to organic substance GO:0071310 132 0.023
regulation of behavior GO:0050795 75 0.023
purine containing compound metabolic process GO:0072521 155 0.022
growth GO:0040007 359 0.022
regulation of developmental growth GO:0048638 174 0.022
triglyceride catabolic process GO:0019433 3 0.022
positive regulation of biosynthetic process GO:0009891 316 0.022
leg disc development GO:0035218 92 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
protein phosphorylation GO:0006468 169 0.022
regulation of catalytic activity GO:0050790 185 0.022
regulation of sequestering of triglyceride GO:0010889 3 0.022
sterol homeostasis GO:0055092 4 0.021
sensory perception of chemical stimulus GO:0007606 116 0.021
cellular amide metabolic process GO:0043603 80 0.021
response to organic cyclic compound GO:0014070 89 0.021
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.021
regionalization GO:0003002 416 0.021
retina development in camera type eye GO:0060041 4 0.021
positive regulation of phosphate metabolic process GO:0045937 139 0.021
phototransduction GO:0007602 52 0.021
negative regulation of gene expression GO:0010629 387 0.021
sensory perception of smell GO:0007608 80 0.020
glycerolipid catabolic process GO:0046503 3 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
regulation of mapk cascade GO:0043408 92 0.020
establishment of planar polarity GO:0001736 87 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
immune response activating signal transduction GO:0002757 2 0.020
carbohydrate derivative catabolic process GO:1901136 118 0.020
negative regulation of rna biosynthetic process GO:1902679 240 0.020
protein dna complex assembly GO:0065004 63 0.020
phosphatidylethanolamine metabolic process GO:0046337 1 0.020
aging GO:0007568 143 0.020
signal transduction by phosphorylation GO:0023014 107 0.020
chemical homeostasis GO:0048878 92 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
open tracheal system development GO:0007424 204 0.019
gland morphogenesis GO:0022612 145 0.019
activation of innate immune response GO:0002218 4 0.019
positive regulation of macromolecule metabolic process GO:0010604 405 0.019
single organism intracellular transport GO:1902582 207 0.019
negative regulation of cell differentiation GO:0045596 143 0.019
cholesterol homeostasis GO:0042632 3 0.019
male courtship behavior tapping to detect pheromone GO:0016544 1 0.019
developmental programmed cell death GO:0010623 138 0.019
cell motility GO:0048870 251 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
positive regulation of developmental process GO:0051094 143 0.018
salivary gland development GO:0007431 162 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
regulation of apoptotic process GO:0042981 130 0.018
ethanolamine containing compound metabolic process GO:0042439 4 0.018
metal ion transport GO:0030001 74 0.018
neutral lipid catabolic process GO:0046461 3 0.018
regulation of transport GO:0051049 181 0.018
sulfur compound metabolic process GO:0006790 59 0.018
positive regulation of developmental growth GO:0048639 62 0.018
compound eye photoreceptor cell differentiation GO:0001751 140 0.018
acylglycerol catabolic process GO:0046464 3 0.018
regulation of programmed cell death GO:0043067 152 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.017
axon guidance GO:0007411 233 0.017
response to lipopolysaccharide GO:0032496 4 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
cell migration GO:0016477 238 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
negative regulation of defense response GO:0031348 35 0.017
taxis GO:0042330 304 0.017
response to organonitrogen compound GO:0010243 75 0.017
nucleosome organization GO:0034728 59 0.017
camera type eye morphogenesis GO:0048593 2 0.017
response to radiation GO:0009314 155 0.017
histolysis GO:0007559 102 0.016
monocarboxylic acid transport GO:0015718 3 0.016
regulation of camp biosynthetic process GO:0030817 12 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
purine containing compound biosynthetic process GO:0072522 30 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
axonogenesis GO:0007409 290 0.016
synaptic transmission GO:0007268 288 0.016
regulation of response to biotic stimulus GO:0002831 63 0.016
salivary gland morphogenesis GO:0007435 145 0.016
protein transport GO:0015031 155 0.016
chemotaxis GO:0006935 249 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.016
regulation of hydrolase activity GO:0051336 97 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
epithelial cell development GO:0002064 274 0.016
regulation of purine nucleotide metabolic process GO:1900542 62 0.016
regulation of protein modification process GO:0031399 112 0.016
photoreceptor cell differentiation GO:0046530 170 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
regulation of cellular component biogenesis GO:0044087 201 0.015
cellular response to molecule of bacterial origin GO:0071219 3 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
exocrine system development GO:0035272 162 0.015
ras protein signal transduction GO:0007265 88 0.015
regulation of immune system process GO:0002682 176 0.015
telencephalon development GO:0021537 2 0.015
organelle fission GO:0048285 340 0.015
peptide metabolic process GO:0006518 80 0.015
neuron projection guidance GO:0097485 241 0.015
chromatin silencing GO:0006342 76 0.015
jnk cascade GO:0007254 50 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
sleep GO:0030431 49 0.015
cellular response to oxygen containing compound GO:1901701 79 0.015
cellular response to lipopolysaccharide GO:0071222 3 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
detection of external stimulus GO:0009581 66 0.015
cell proliferation GO:0008283 299 0.015
ion transport GO:0006811 145 0.015
nucleotide catabolic process GO:0009166 109 0.015
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.015
defense response to gram negative bacterium GO:0050829 94 0.015
regulation of innate immune response GO:0045088 71 0.015
salivary gland histolysis GO:0035070 88 0.015
organophosphate catabolic process GO:0046434 112 0.015
aromatic compound catabolic process GO:0019439 166 0.015
apoptotic process GO:0006915 159 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
cation transport GO:0006812 110 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
proteolysis GO:0006508 192 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
phototaxis GO:0042331 21 0.014
regulation of growth GO:0040008 233 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
embryonic pattern specification GO:0009880 174 0.014
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
humoral immune response GO:0006959 117 0.014
mapk cascade GO:0000165 107 0.014
developmental maturation GO:0021700 172 0.014
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.014
regulation of cell cycle GO:0051726 291 0.014
locomotory behavior GO:0007626 176 0.014
camp metabolic process GO:0046058 19 0.014
response to extracellular stimulus GO:0009991 116 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
regulation of organelle organization GO:0033043 196 0.014
larval behavior GO:0030537 42 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
pattern recognition receptor signaling pathway GO:0002221 2 0.014
phosphatidic acid metabolic process GO:0046473 1 0.014
negative regulation of signaling GO:0023057 219 0.014
regulation of nervous system development GO:0051960 248 0.014
regulation of cell development GO:0060284 215 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
regulation of defense response GO:0031347 102 0.014
stress activated mapk cascade GO:0051403 52 0.014
rna processing GO:0006396 147 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
neuron fate commitment GO:0048663 50 0.013
positive regulation of cell migration GO:0030335 2 0.013
autophagic cell death GO:0048102 83 0.013
epithelial cell migration GO:0010631 148 0.013
transmembrane transport GO:0055085 139 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
positive regulation of lipid storage GO:0010884 4 0.013
amide biosynthetic process GO:0043604 42 0.013
segmentation GO:0035282 207 0.013
establishment of protein localization GO:0045184 163 0.013
negative regulation of cell communication GO:0010648 223 0.013
nucleoside metabolic process GO:0009116 127 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
cellular response to biotic stimulus GO:0071216 4 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
single organism cellular localization GO:1902580 180 0.013
heterocycle catabolic process GO:0046700 166 0.013
organic acid metabolic process GO:0006082 103 0.013
lipid homeostasis GO:0055088 33 0.013
respiratory system development GO:0060541 213 0.013
acid secretion GO:0046717 1 0.013
response to wounding GO:0009611 94 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
tissue migration GO:0090130 155 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
nucleoside phosphate biosynthetic process GO:1901293 34 0.013
secondary metabolic process GO:0019748 75 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
anatomical structure homeostasis GO:0060249 97 0.013
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.012
positive regulation of gene expression GO:0010628 290 0.012
imaginal disc derived leg morphogenesis GO:0007480 80 0.012
anion homeostasis GO:0055081 3 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
positive regulation of molecular function GO:0044093 136 0.012
negative regulation of cell death GO:0060548 81 0.012
cholesterol transport GO:0030301 2 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
regulation of catabolic process GO:0009894 170 0.012
inter male aggressive behavior GO:0002121 60 0.012
regulation of lipid transport GO:0032368 3 0.012
positive regulation of cell motility GO:2000147 3 0.012
tissue death GO:0016271 102 0.012
biological adhesion GO:0022610 138 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
detection of light stimulus GO:0009583 58 0.012
dendrite development GO:0016358 204 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
embryonic morphogenesis GO:0048598 206 0.012
antimicrobial humoral response GO:0019730 99 0.012
purine ribonucleotide biosynthetic process GO:0009152 28 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
positive regulation of multi organism process GO:0043902 40 0.011
response to oxidative stress GO:0006979 86 0.011
acylglycerol biosynthetic process GO:0046463 2 0.011
regulation of cell differentiation GO:0045595 302 0.011
cytoplasmic transport GO:0016482 130 0.011
positive regulation of transport GO:0051050 92 0.011
negative regulation of developmental process GO:0051093 201 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
response to oxygen levels GO:0070482 59 0.011
regulation of production of molecular mediator of immune response GO:0002700 44 0.011
peptide biosynthetic process GO:0043043 42 0.011
regulation of cell cycle process GO:0010564 181 0.011
mitotic spindle organization GO:0007052 220 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
intracellular transport GO:0046907 228 0.011
cell division GO:0051301 248 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
positive regulation of immune response GO:0050778 63 0.011
regulation of cellular response to stress GO:0080135 89 0.011
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.011
multicellular organismal homeostasis GO:0048871 41 0.011
regulation of cell size GO:0008361 63 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
eye antennal disc development GO:0035214 60 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
positive regulation of protein metabolic process GO:0051247 128 0.011
nucleosome assembly GO:0006334 35 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
regulation of sterol transport GO:0032371 1 0.010
notch signaling pathway GO:0007219 120 0.010
central nervous system development GO:0007417 201 0.010
cellular ketone metabolic process GO:0042180 24 0.010
posttranscriptional regulation of gene expression GO:0010608 145 0.010
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
positive regulation of catabolic process GO:0009896 105 0.010
energy taxis GO:0009453 21 0.010
immune effector process GO:0002252 98 0.010
response to copper ion GO:0046688 4 0.010
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.010
regulation of cellular component size GO:0032535 98 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
connective tissue development GO:0061448 3 0.010
positive regulation of defense response GO:0031349 59 0.010
macromolecule catabolic process GO:0009057 161 0.010
ribonucleotide biosynthetic process GO:0009260 28 0.010
rho protein signal transduction GO:0007266 14 0.010
regulation of cellular localization GO:0060341 136 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010
eye photoreceptor cell development GO:0042462 81 0.010
negative regulation of insulin secretion GO:0046676 1 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010

SIFR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.057
disease of metabolism DOID:0014667 0 0.029
acquired metabolic disease DOID:0060158 0 0.029
nervous system disease DOID:863 0 0.018
carbohydrate metabolism disease DOID:0050013 0 0.013
glucose metabolism disease DOID:4194 0 0.013
cardiovascular system disease DOID:1287 0 0.013
musculoskeletal system disease DOID:17 0 0.012
inherited metabolic disorder DOID:655 0 0.011
diabetes mellitus DOID:9351 0 0.011
sensory system disease DOID:0050155 0 0.011
integumentary system disease DOID:16 0 0.010