Drosophila melanogaster

74 known processes

Gdi (Dmel_CG4422)

GDP dissociation inhibitor

(Aliases: dGDI,rab GDI,l(2)N7-3,GdI,N7-3,GDI,Dmel\CG4422,CG4422)

Gdi biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of cellular biosynthetic process GO:0031327 277 0.933
negative regulation of biosynthetic process GO:0009890 277 0.692
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.678
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.625
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.550
cell proliferation GO:0008283 299 0.543
negative regulation of cellular metabolic process GO:0031324 382 0.515
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.444
cell death GO:0008219 279 0.418
Worm
negative regulation of rna biosynthetic process GO:1902679 240 0.415
negative regulation of gene expression GO:0010629 387 0.315
negative regulation of rna metabolic process GO:0051253 251 0.296
central nervous system development GO:0007417 201 0.291
negative regulation of transcription dna templated GO:0045892 237 0.265
response to organic substance GO:0010033 284 0.251
positive regulation of macromolecule metabolic process GO:0010604 405 0.246
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.241
brain development GO:0007420 120 0.214
cell migration GO:0016477 238 0.213
programmed cell death GO:0012501 257 0.205
transcription from rna polymerase ii promoter GO:0006366 368 0.203
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.172
embryo development ending in birth or egg hatching GO:0009792 152 0.126
Worm
negative regulation of nucleic acid templated transcription GO:1903507 240 0.121
spindle organization GO:0007051 253 0.119
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.114
organelle fission GO:0048285 340 0.112
catabolic process GO:0009056 409 0.111
instar larval development GO:0002168 55 0.110
positive regulation of rna biosynthetic process GO:1902680 266 0.109
rna localization GO:0006403 115 0.109
death GO:0016265 284 0.104
Worm
head development GO:0060322 135 0.102
positive regulation of gene expression GO:0010628 290 0.101
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.100
sex differentiation GO:0007548 81 0.096
apoptotic process GO:0006915 159 0.092
positive regulation of signal transduction GO:0009967 223 0.090
epithelial cell migration GO:0010631 148 0.084
positive regulation of nucleic acid templated transcription GO:1903508 266 0.083
cellular response to chemical stimulus GO:0070887 199 0.079
cellular macromolecule localization GO:0070727 220 0.077
Human
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.077
negative regulation of signaling GO:0023057 219 0.076
mitotic nuclear division GO:0007067 213 0.075
regulation of transport GO:0051049 181 0.066
Human
mitotic spindle organization GO:0007052 220 0.066
protein modification process GO:0036211 438 0.066
positive regulation of cellular biosynthetic process GO:0031328 316 0.060
molting cycle GO:0042303 56 0.059
negative regulation of protein metabolic process GO:0051248 85 0.056
secondary metabolic process GO:0019748 75 0.054
regulation of cellular protein metabolic process GO:0032268 243 0.054
columnar cuboidal epithelial cell development GO:0002066 249 0.054
positive regulation of biosynthetic process GO:0009891 316 0.054
cellular catabolic process GO:0044248 372 0.053
nucleotide catabolic process GO:0009166 109 0.053
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.053
regulation of cellular localization GO:0060341 136 0.052
Human
protein localization to nucleus GO:0034504 55 0.051
regulation of protein metabolic process GO:0051246 256 0.050
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.050
cell motility GO:0048870 251 0.050
reproductive system development GO:0061458 74 0.049
regulation of cell proliferation GO:0042127 163 0.048
epithelium migration GO:0090132 148 0.048
positive regulation of response to stimulus GO:0048584 323 0.047
organic substance catabolic process GO:1901575 308 0.047
regulation of cell death GO:0010941 173 0.046
chromosome segregation GO:0007059 157 0.045
development of primary sexual characteristics GO:0045137 50 0.045
phagocytosis GO:0006909 215 0.045
oocyte anterior posterior axis specification GO:0007314 72 0.044
response to nutrient levels GO:0031667 114 0.043
oocyte microtubule cytoskeleton organization GO:0016325 35 0.042
response to abiotic stimulus GO:0009628 341 0.041
positive regulation of rna metabolic process GO:0051254 271 0.040
vesicle mediated transport GO:0016192 381 0.039
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.037
regulation of localization GO:0032879 275 0.037
Human
protein localization GO:0008104 284 0.036
Human
response to endogenous stimulus GO:0009719 119 0.036
protein dna complex subunit organization GO:0071824 86 0.036
macromolecular complex assembly GO:0065003 256 0.035
localization of cell GO:0051674 257 0.033
small molecule metabolic process GO:0044281 305 0.033
multicellular organismal reproductive behavior GO:0033057 110 0.033
phagocytosis engulfment GO:0006911 11 0.033
cellular macromolecular complex assembly GO:0034622 153 0.032
nuclear division GO:0000280 332 0.032
positive regulation of cell communication GO:0010647 250 0.032
rhythmic process GO:0048511 106 0.031
positive regulation of signaling GO:0023056 243 0.031
cellular response to extracellular stimulus GO:0031668 64 0.031
gene silencing by rna GO:0031047 57 0.031
regulation of nuclear division GO:0051783 58 0.030
regulation of intracellular transport GO:0032386 64 0.030
Human
striated muscle cell differentiation GO:0051146 90 0.030
intracellular transport GO:0046907 228 0.030
Human
negative regulation of signal transduction GO:0009968 206 0.030
response to oxygen containing compound GO:1901700 200 0.029
regulation of apoptotic process GO:0042981 130 0.029
eye photoreceptor cell differentiation GO:0001754 145 0.028
proteolysis GO:0006508 192 0.028
cellular protein localization GO:0034613 160 0.027
Human
mitochondrion organization GO:0007005 65 0.027
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.026
posttranscriptional regulation of gene expression GO:0010608 145 0.026
endocytosis GO:0006897 310 0.026
negative regulation of cell communication GO:0010648 223 0.026
epithelial cell development GO:0002064 274 0.026
epithelial cell differentiation GO:0030855 322 0.025
regulation of phosphate metabolic process GO:0019220 210 0.025
negative regulation of cellular protein metabolic process GO:0032269 85 0.025
organophosphate catabolic process GO:0046434 112 0.025
oocyte development GO:0048599 124 0.024
regulation of mitotic cell cycle GO:0007346 190 0.024
pole plasm assembly GO:0007315 61 0.024
protein complex biogenesis GO:0070271 201 0.024
response to oxygen levels GO:0070482 59 0.024
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.024
modification dependent protein catabolic process GO:0019941 78 0.023
regulation of organelle organization GO:0033043 196 0.023
ubiquitin dependent protein catabolic process GO:0006511 78 0.023
oocyte construction GO:0007308 112 0.022
ribose phosphate metabolic process GO:0019693 145 0.022
circadian rhythm GO:0007623 105 0.022
negative regulation of cellular component organization GO:0051129 108 0.021
Human
intracellular receptor signaling pathway GO:0030522 19 0.021
aromatic compound catabolic process GO:0019439 166 0.021
regulation of cell cycle process GO:0010564 181 0.020
ribonucleoside triphosphate metabolic process GO:0009199 119 0.020
growth GO:0040007 359 0.020
purine containing compound catabolic process GO:0072523 112 0.020
immune system process GO:0002376 347 0.019
eye morphogenesis GO:0048592 260 0.019
single organism catabolic process GO:0044712 228 0.019
positive regulation of growth GO:0045927 75 0.019
regulation of cell differentiation GO:0045595 302 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.018
regulation of phosphorus metabolic process GO:0051174 210 0.018
aging GO:0007568 143 0.018
Worm
dna metabolic process GO:0006259 227 0.018
membrane invagination GO:0010324 11 0.018
establishment of localization in cell GO:0051649 402 0.018
Human
ovarian follicle cell development GO:0030707 248 0.018
regulation of programmed cell death GO:0043067 152 0.017
cellular response to organic substance GO:0071310 132 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
reproductive structure development GO:0048608 74 0.017
modification dependent macromolecule catabolic process GO:0043632 79 0.017
cytoplasmic transport GO:0016482 130 0.017
carbohydrate derivative catabolic process GO:1901136 118 0.016
developmental growth GO:0048589 280 0.016
positive regulation of developmental process GO:0051094 143 0.016
larval development GO:0002164 104 0.016
negative regulation of cell death GO:0060548 81 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
developmental maturation GO:0021700 172 0.016
regulation of catabolic process GO:0009894 170 0.016
cellular protein catabolic process GO:0044257 83 0.016
defense response GO:0006952 300 0.016
cellular protein modification process GO:0006464 438 0.015
tissue morphogenesis GO:0048729 297 0.015
organic acid metabolic process GO:0006082 103 0.015
tube development GO:0035295 244 0.015
intracellular signal transduction GO:0035556 300 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
positive regulation of cellular protein metabolic process GO:0032270 118 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
cellular component assembly involved in morphogenesis GO:0010927 151 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
response to ecdysone GO:0035075 34 0.015
multi organism behavior GO:0051705 175 0.015
negative regulation of catabolic process GO:0009895 36 0.014
regulation of cell cycle GO:0051726 291 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
axon development GO:0061564 297 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
dendrite morphogenesis GO:0048813 199 0.014
regulation of notch signaling pathway GO:0008593 100 0.014
response to hypoxia GO:0001666 53 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
regionalization GO:0003002 416 0.014
positive regulation of transport GO:0051050 92 0.014
oocyte axis specification GO:0007309 108 0.013
response to wounding GO:0009611 94 0.013
meiotic cell cycle GO:0051321 171 0.013
embryonic pattern specification GO:0009880 174 0.013
chromosome localization GO:0050000 20 0.013
appendage development GO:0048736 401 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
forebrain development GO:0030900 2 0.012
regulation of growth GO:0040008 233 0.012
cell cycle phase transition GO:0044770 140 0.012
cell maturation GO:0048469 144 0.012
striated muscle cell development GO:0055002 50 0.012
stem cell differentiation GO:0048863 117 0.012
single organism cellular localization GO:1902580 180 0.012
Human
nucleoside phosphate catabolic process GO:1901292 110 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
regulation of locomotion GO:0040012 42 0.012
rna splicing GO:0008380 83 0.012
response to monosaccharide GO:0034284 4 0.012
protein dna complex assembly GO:0065004 63 0.011
protein maturation GO:0051604 71 0.011
organelle localization GO:0051640 148 0.011
response to external biotic stimulus GO:0043207 293 0.011
nucleotide metabolic process GO:0009117 161 0.011
fertilization GO:0009566 26 0.011
single organism behavior GO:0044708 391 0.011
negative regulation of developmental process GO:0051093 201 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
regulation of cell division GO:0051302 72 0.011
cellular component disassembly GO:0022411 46 0.011
retina development in camera type eye GO:0060041 4 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
telencephalon development GO:0021537 2 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
protein complex assembly GO:0006461 200 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
single organism membrane organization GO:0044802 93 0.011
Human
reproductive behavior GO:0019098 122 0.011
salivary gland development GO:0007431 162 0.011
spindle localization GO:0051653 22 0.011
nuclear import GO:0051170 51 0.010
innate immune response GO:0045087 144 0.010
protein transport GO:0015031 155 0.010
Human
proteasomal protein catabolic process GO:0010498 59 0.010
camera type eye development GO:0043010 4 0.010
striated muscle myosin thick filament assembly GO:0071688 3 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
nucleoside catabolic process GO:0009164 112 0.010
epithelial tube morphogenesis GO:0060562 88 0.010
blastoderm segmentation GO:0007350 159 0.010
cellular nitrogen compound catabolic process GO:0044270 165 0.010

Gdi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
nervous system disease DOID:863 0 0.015