Drosophila melanogaster

24 known processes

TotC (Dmel_CG31508)

Turandot C

(Aliases: TOTc,totC,CG31508,Dmel\CG31508,tot)

TotC biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to other organism GO:0051707 293 0.061
response to biotic stimulus GO:0009607 294 0.060
response to bacterium GO:0009617 198 0.059
response to external biotic stimulus GO:0043207 293 0.042
defense response GO:0006952 300 0.041
positive regulation of response to stimulus GO:0048584 323 0.041
response to organic substance GO:0010033 284 0.041
Fly
organonitrogen compound metabolic process GO:1901564 318 0.040
cellular response to heat GO:0034605 24 0.039
intracellular signal transduction GO:0035556 300 0.035
response to oxygen containing compound GO:1901700 200 0.034
Fly
phosphorylation GO:0016310 294 0.034
body morphogenesis GO:0010171 2 0.034
cellular response to chemical stimulus GO:0070887 199 0.032
Fly
neurological system process GO:0050877 358 0.032
innate immune response GO:0045087 144 0.031
defense response to other organism GO:0098542 225 0.030
single organism behavior GO:0044708 391 0.030
regulation of intracellular signal transduction GO:1902531 236 0.030
positive regulation of macromolecule metabolic process GO:0010604 405 0.029
organic substance catabolic process GO:1901575 308 0.029
response to lipopolysaccharide GO:0032496 4 0.028
lateral inhibition GO:0046331 206 0.028
organic substance transport GO:0071702 257 0.028
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.028
catabolic process GO:0009056 409 0.027
response to temperature stimulus GO:0009266 106 0.027
defense response to bacterium GO:0042742 178 0.026
endocytosis GO:0006897 310 0.025
immune response GO:0006955 246 0.025
response to abiotic stimulus GO:0009628 341 0.025
compound eye development GO:0048749 307 0.024
vesicle mediated transport GO:0016192 381 0.024
eye development GO:0001654 323 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
immune response regulating signaling pathway GO:0002764 2 0.023
cell death GO:0008219 279 0.023
organic acid metabolic process GO:0006082 103 0.023
protein modification process GO:0036211 438 0.023
cellular response to radiation GO:0071478 52 0.023
cellular amino acid metabolic process GO:0006520 61 0.023
chorion containing eggshell formation GO:0007304 105 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
cellular protein modification process GO:0006464 438 0.022
sensory perception GO:0007600 196 0.022
imaginal disc derived wing morphogenesis GO:0007476 337 0.022
carboxylic acid metabolic process GO:0019752 92 0.022
eye morphogenesis GO:0048592 260 0.021
macromolecule catabolic process GO:0009057 161 0.021
imaginal disc derived appendage morphogenesis GO:0035114 395 0.021
cellular catabolic process GO:0044248 372 0.021
epithelial cell differentiation GO:0030855 322 0.021
cell cell signaling involved in cell fate commitment GO:0045168 210 0.021
compound eye morphogenesis GO:0001745 249 0.021
immune response activating signal transduction GO:0002757 2 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
immune system process GO:0002376 347 0.020
cell proliferation GO:0008283 299 0.020
regulation of immune response GO:0050776 118 0.020
appendage development GO:0048736 401 0.020
camera type eye development GO:0043010 4 0.020
sensory organ morphogenesis GO:0090596 260 0.020
regulation of phosphorus metabolic process GO:0051174 210 0.020
humoral immune response GO:0006959 117 0.020
regulation of cellular amino acid metabolic process GO:0006521 0 0.019
cellular response to lipopolysaccharide GO:0071222 3 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
oxoacid metabolic process GO:0043436 103 0.019
phagocytosis GO:0006909 215 0.019
programmed cell death GO:0012501 257 0.019
positive regulation of gene expression GO:0010628 290 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
establishment of localization in cell GO:0051649 402 0.019
response to mercury ion GO:0046689 3 0.019
Fly
regulation of cell cycle GO:0051726 291 0.019
mitotic cell cycle phase transition GO:0044772 138 0.019
regulation of response to stress GO:0080134 200 0.019
positive regulation of cell communication GO:0010647 250 0.019
homeostatic process GO:0042592 199 0.019
cellular response to molecule of bacterial origin GO:0071219 3 0.018
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.018
steroid catabolic process GO:0006706 1 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
death GO:0016265 284 0.018
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.018
appendage morphogenesis GO:0035107 397 0.018
organonitrogen compound biosynthetic process GO:1901566 117 0.018
single organism catabolic process GO:0044712 228 0.017
regulation of defense response GO:0031347 102 0.017
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.017
positive regulation of signal transduction GO:0009967 223 0.017
positive regulation of biosynthetic process GO:0009891 316 0.017
forebrain development GO:0030900 2 0.017
single organism biosynthetic process GO:0044711 206 0.017
regulation of protein metabolic process GO:0051246 256 0.017
small molecule metabolic process GO:0044281 305 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
negative regulation of response to stimulus GO:0048585 258 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
cell migration GO:0016477 238 0.017
aging GO:0007568 143 0.017
chromosome organization GO:0051276 360 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
cellular response to oxidative stress GO:0034599 28 0.016
Fly
negative regulation of cell communication GO:0010648 223 0.016
spindle organization GO:0007051 253 0.016
kidney development GO:0001822 3 0.016
defense response to gram negative bacterium GO:0050829 94 0.016
epithelial cell development GO:0002064 274 0.016
multicellular organismal aging GO:0010259 140 0.016
wing disc morphogenesis GO:0007472 344 0.016
proteolysis GO:0006508 192 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
positive regulation of signaling GO:0023056 243 0.016
regulation of cellular protein metabolic process GO:0032268 243 0.016
cellular response to abiotic stimulus GO:0071214 58 0.016
response to organophosphorus GO:0046683 2 0.016
amine metabolic process GO:0009308 12 0.016
cellular amine metabolic process GO:0044106 12 0.016
cuticle development GO:0042335 86 0.016
cellular macromolecule catabolic process GO:0044265 136 0.016
cellular response to light stimulus GO:0071482 37 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
determination of adult lifespan GO:0008340 137 0.015
cell cycle phase transition GO:0044770 140 0.015
response to heat GO:0009408 63 0.015
cellular response to biotic stimulus GO:0071216 4 0.015
cellular ketone metabolic process GO:0042180 24 0.015
regulation of phosphorylation GO:0042325 147 0.015
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.015
positive regulation of cell motility GO:2000147 3 0.015
positive regulation of rna biosynthetic process GO:1902680 266 0.015
ion transport GO:0006811 145 0.015
developmental pigmentation GO:0048066 68 0.015
regulation of multi organism process GO:0043900 131 0.015
rna processing GO:0006396 147 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
response to light stimulus GO:0009416 124 0.015
purine containing compound metabolic process GO:0072521 155 0.015
axis specification GO:0009798 167 0.015
connective tissue development GO:0061448 3 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
protein phosphorylation GO:0006468 169 0.015
negative regulation of rna metabolic process GO:0051253 251 0.015
growth GO:0040007 359 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.015
negative regulation of developmental process GO:0051093 201 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
taxis GO:0042330 304 0.014
intracellular transport GO:0046907 228 0.014
chemotaxis GO:0006935 249 0.014
regulation of phosphate metabolic process GO:0019220 210 0.014
chromosome segregation GO:0007059 157 0.014
protein localization GO:0008104 284 0.014
regulation of mitotic cell cycle phase transition GO:1901990 130 0.014
response to radiation GO:0009314 155 0.014
exocrine system development GO:0035272 162 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
negative regulation of gene expression GO:0010629 387 0.014
regionalization GO:0003002 416 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
regulation of localization GO:0032879 275 0.014
cellular response to organic substance GO:0071310 132 0.014
adult locomotory behavior GO:0008344 76 0.013
negative regulation of signaling GO:0023057 219 0.013
organelle fission GO:0048285 340 0.013
cell division GO:0051301 248 0.013
antimicrobial humoral response GO:0019730 99 0.013
dna metabolic process GO:0006259 227 0.013
response to oxidative stress GO:0006979 86 0.013
mrna metabolic process GO:0016071 124 0.013
nuclear division GO:0000280 332 0.013
mitotic nuclear division GO:0007067 213 0.013
nucleoside phosphate metabolic process GO:0006753 162 0.013
response to nutrient levels GO:0031667 114 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
response to hexose GO:0009746 3 0.013
regulation of immune system process GO:0002682 176 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
regulation of cell death GO:0010941 173 0.013
positive regulation of cell migration GO:0030335 2 0.013
male gamete generation GO:0048232 201 0.013
regulation of catalytic activity GO:0050790 185 0.013
heterocycle catabolic process GO:0046700 166 0.013
mitotic spindle organization GO:0007052 220 0.013
eggshell formation GO:0030703 105 0.013
regulation of cellular component biogenesis GO:0044087 201 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
developmental maturation GO:0021700 172 0.013
macromolecular complex assembly GO:0065003 256 0.013
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
segmentation GO:0035282 207 0.013
neuron projection guidance GO:0097485 241 0.013
hindbrain development GO:0030902 2 0.013
cellular macromolecule localization GO:0070727 220 0.013
autophagic cell death GO:0048102 83 0.013
regulation of molecular function GO:0065009 217 0.013
regulation of cell cycle phase transition GO:1901987 130 0.013
protein transport GO:0015031 155 0.013
regulation of organelle organization GO:0033043 196 0.013
mapk cascade GO:0000165 107 0.013
negative regulation of signal transduction GO:0009968 206 0.013
response to nitrogen compound GO:1901698 90 0.013
nitrogen compound transport GO:0071705 85 0.013
immune effector process GO:0002252 98 0.013
activation of innate immune response GO:0002218 4 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.012
innate immune response activating signal transduction GO:0002758 2 0.012
regulation of cell cycle process GO:0010564 181 0.012
ovarian follicle cell development GO:0030707 248 0.012
detection of chemical stimulus GO:0009593 93 0.012
establishment of protein localization GO:0045184 163 0.012
mating GO:0007618 120 0.012
organelle assembly GO:0070925 198 0.012
single organism cellular localization GO:1902580 180 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
regulation of mapk cascade GO:0043408 92 0.012
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
protein complex biogenesis GO:0070271 201 0.012
regulation of innate immune response GO:0045088 71 0.012
small gtpase mediated signal transduction GO:0007264 88 0.012
detection of stimulus GO:0051606 156 0.012
tissue death GO:0016271 102 0.012
tripartite regional subdivision GO:0007351 103 0.012
chromatin modification GO:0016568 147 0.012
single organism intracellular transport GO:1902582 207 0.012
androgen metabolic process GO:0008209 1 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
response to organic cyclic compound GO:0014070 89 0.012
developmental growth GO:0048589 280 0.012
salivary gland morphogenesis GO:0007435 145 0.012
negative regulation of cellular biosynthetic process GO:0031327 277 0.012
organophosphate metabolic process GO:0019637 195 0.012
positive regulation of nucleic acid templated transcription GO:1903508 266 0.012
chromatin organization GO:0006325 207 0.012
locomotory behavior GO:0007626 176 0.012
response to extracellular stimulus GO:0009991 116 0.012
gland morphogenesis GO:0022612 145 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
salivary gland histolysis GO:0035070 88 0.012
pattern recognition receptor signaling pathway GO:0002221 2 0.012
positive regulation of molecular function GO:0044093 136 0.012
transmembrane transport GO:0055085 139 0.012
cholesterol homeostasis GO:0042632 3 0.012
pigment metabolic process GO:0042440 84 0.012
endomembrane system organization GO:0010256 119 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
sensory perception of chemical stimulus GO:0007606 116 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
aromatic compound catabolic process GO:0019439 166 0.011
protein catabolic process GO:0030163 101 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
cellular response to external stimulus GO:0071496 66 0.011
Fly
regulation of response to biotic stimulus GO:0002831 63 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
developmental programmed cell death GO:0010623 138 0.011
adult behavior GO:0030534 137 0.011
salivary gland development GO:0007431 162 0.011
positive regulation of intracellular signal transduction GO:1902533 116 0.011
regulation of programmed cell death GO:0043067 152 0.011
central nervous system development GO:0007417 201 0.011
spermatogenesis GO:0007283 200 0.011
blastoderm segmentation GO:0007350 159 0.011
mrna processing GO:0006397 104 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
sterol homeostasis GO:0055092 4 0.011
axon development GO:0061564 297 0.011
nucleotide metabolic process GO:0009117 161 0.011
axon guidance GO:0007411 233 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
cell motility GO:0048870 251 0.011
rhythmic process GO:0048511 106 0.011
response to wounding GO:0009611 94 0.011
histolysis GO:0007559 102 0.011
cellular response to uv GO:0034644 12 0.011
wound healing GO:0042060 75 0.011
ras protein signal transduction GO:0007265 88 0.011
anion homeostasis GO:0055081 3 0.011
chemosensory behavior GO:0007635 106 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
chaeta development GO:0022416 97 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
anterior posterior pattern specification GO:0009952 136 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
protein complex assembly GO:0006461 200 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of apoptotic process GO:0042981 130 0.011
embryonic axis specification GO:0000578 107 0.011
purine nucleotide metabolic process GO:0006163 146 0.011
multi organism behavior GO:0051705 175 0.011
regulation of response to external stimulus GO:0032101 115 0.011
defense response to gram positive bacterium GO:0050830 41 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
regulation of nervous system development GO:0051960 248 0.011
mesenchymal cell development GO:0014031 1 0.011
telencephalon development GO:0021537 2 0.010
tissue morphogenesis GO:0048729 297 0.010
negative regulation of immune response GO:0050777 39 0.010
camera type eye morphogenesis GO:0048593 2 0.010
open tracheal system development GO:0007424 204 0.010
gland development GO:0048732 191 0.010
actin cytoskeleton organization GO:0030036 206 0.010
regulation of cell development GO:0060284 215 0.010
anterior posterior axis specification GO:0009948 109 0.010
photoreceptor cell development GO:0042461 96 0.010
ribonucleoside metabolic process GO:0009119 127 0.010
positive regulation of defense response GO:0031349 59 0.010
cellular protein localization GO:0034613 160 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
glycosyl compound metabolic process GO:1901657 127 0.010
negative regulation of immune system process GO:0002683 50 0.010
mesenchymal cell differentiation GO:0048762 1 0.010
dorsal ventral pattern formation GO:0009953 133 0.010
positive regulation of lipid storage GO:0010884 4 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
vitamin metabolic process GO:0006766 2 0.010
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.010
chitin based cuticle development GO:0040003 49 0.010
regulation of gene expression epigenetic GO:0040029 128 0.010

TotC disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.042
nervous system disease DOID:863 0 0.020
disease of metabolism DOID:0014667 0 0.018
cardiovascular system disease DOID:1287 0 0.014
inherited metabolic disorder DOID:655 0 0.014
acquired metabolic disease DOID:0060158 0 0.013
artery disease DOID:0050828 0 0.012
vascular disease DOID:178 0 0.012
central nervous system disease DOID:331 0 0.012
neurodegenerative disease DOID:1289 0 0.012
musculoskeletal system disease DOID:17 0 0.010