Drosophila melanogaster

41 known processes

TotA (Dmel_CG31509)

Turandot A

(Aliases: totA,Turt,Dmel\CG31509,tot,Tot,Tot-A,CG31509)

TotA biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to mercury ion GO:0046689 3 0.434
insecticide catabolic process GO:0046701 1 0.363
lauric acid metabolic process GO:0048252 1 0.325
defense response to other organism GO:0098542 225 0.231
insecticide metabolic process GO:0017143 2 0.222
secondary metabolite catabolic process GO:0090487 1 0.204
toxin catabolic process GO:0009407 1 0.177
response to other organism GO:0051707 293 0.176
xenobiotic catabolic process GO:0042178 1 0.170
secondary metabolic process GO:0019748 75 0.138
response to organophosphorus GO:0046683 2 0.131
fat soluble vitamin biosynthetic process GO:0042362 1 0.125
defense response GO:0006952 300 0.120
steroid catabolic process GO:0006706 1 0.117
response to organic substance GO:0010033 284 0.116
response to external biotic stimulus GO:0043207 293 0.115
vitamin biosynthetic process GO:0009110 1 0.114
vitamin metabolic process GO:0006766 2 0.106
catabolic process GO:0009056 409 0.103
response to bacterium GO:0009617 198 0.101
lipid metabolic process GO:0006629 121 0.098
cellular catabolic process GO:0044248 372 0.095
response to biotic stimulus GO:0009607 294 0.095
defense response to bacterium GO:0042742 178 0.090
response to insecticide GO:0017085 14 0.083
organonitrogen compound metabolic process GO:1901564 318 0.073
positive regulation of gene expression GO:0010628 290 0.071
organic hydroxy compound metabolic process GO:1901615 83 0.071
small molecule metabolic process GO:0044281 305 0.068
organonitrogen compound catabolic process GO:1901565 128 0.065
homeostatic process GO:0042592 199 0.060
carboxylic acid metabolic process GO:0019752 92 0.060
single organism behavior GO:0044708 391 0.059
polyol biosynthetic process GO:0046173 3 0.058
organic substance catabolic process GO:1901575 308 0.057
immune system process GO:0002376 347 0.056
oxoacid metabolic process GO:0043436 103 0.056
single organism catabolic process GO:0044712 228 0.056
cellular ketone metabolic process GO:0042180 24 0.056
imaginal disc derived appendage morphogenesis GO:0035114 395 0.055
developmental growth GO:0048589 280 0.055
response to metal ion GO:0010038 23 0.055
anion homeostasis GO:0055081 3 0.055
behavioral response to ethanol GO:0048149 49 0.054
growth GO:0040007 359 0.054
cellular response to chemical stimulus GO:0070887 199 0.054
wing disc morphogenesis GO:0007472 344 0.053
ion homeostasis GO:0050801 55 0.053
cellular hormone metabolic process GO:0034754 23 0.052
cellular ion homeostasis GO:0006873 39 0.051
response to oxygen containing compound GO:1901700 200 0.050
imaginal disc derived appendage development GO:0048737 399 0.050
response to abiotic stimulus GO:0009628 341 0.050
multi organism behavior GO:0051705 175 0.048
response to toxic substance GO:0009636 22 0.048
nuclear division GO:0000280 332 0.047
post embryonic appendage morphogenesis GO:0035120 385 0.046
aging GO:0007568 143 0.046
appendage development GO:0048736 401 0.045
regulation of anatomical structure size GO:0090066 163 0.045
response to organic cyclic compound GO:0014070 89 0.044
cellular lipid metabolic process GO:0044255 83 0.043
organic hydroxy compound biosynthetic process GO:1901617 21 0.043
aggressive behavior GO:0002118 63 0.042
ketone biosynthetic process GO:0042181 16 0.042
organic acid metabolic process GO:0006082 103 0.042
sensory perception of chemical stimulus GO:0007606 116 0.042
steroid biosynthetic process GO:0006694 16 0.041
medium chain fatty acid metabolic process GO:0051791 1 0.041
regulation of growth GO:0040008 233 0.039
cellular nitrogen compound catabolic process GO:0044270 165 0.038
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
positive regulation of macromolecule metabolic process GO:0010604 405 0.038
chemical homeostasis GO:0048878 92 0.038
cellular amine metabolic process GO:0044106 12 0.038
response to nitrogen compound GO:1901698 90 0.038
single organism biosynthetic process GO:0044711 206 0.037
defense response to gram negative bacterium GO:0050829 94 0.037
protein modification process GO:0036211 438 0.037
hormone metabolic process GO:0042445 33 0.037
organelle fission GO:0048285 340 0.036
phosphorylation GO:0016310 294 0.036
immune response GO:0006955 246 0.036
columnar cuboidal epithelial cell development GO:0002066 249 0.036
positive regulation of multicellular organismal process GO:0051240 143 0.036
ecdysteroid metabolic process GO:0045455 19 0.036
response to ddt GO:0046680 5 0.036
organophosphate metabolic process GO:0019637 195 0.035
vesicle mediated transport GO:0016192 381 0.035
cellular amino acid metabolic process GO:0006520 61 0.034
lipid biosynthetic process GO:0008610 46 0.034
immune response regulating signaling pathway GO:0002764 2 0.034
neurological system process GO:0050877 358 0.034
small molecule biosynthetic process GO:0044283 37 0.033
amine metabolic process GO:0009308 12 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.033
intracellular signal transduction GO:0035556 300 0.031
ethanolamine containing compound metabolic process GO:0042439 4 0.031
ecdysteroid biosynthetic process GO:0045456 15 0.031
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.031
cellular homeostasis GO:0019725 80 0.030
appendage morphogenesis GO:0035107 397 0.029
positive regulation of cell communication GO:0010647 250 0.029
positive regulation of signaling GO:0023056 243 0.029
epithelium migration GO:0090132 148 0.029
cellular protein modification process GO:0006464 438 0.028
positive regulation of signal transduction GO:0009967 223 0.028
cell proliferation GO:0008283 299 0.027
cell death GO:0008219 279 0.027
taxis GO:0042330 304 0.027
septate junction assembly GO:0019991 26 0.026
alcohol metabolic process GO:0006066 25 0.026
cellular macromolecule localization GO:0070727 220 0.026
regulation of protein metabolic process GO:0051246 256 0.026
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.026
adult behavior GO:0030534 137 0.026
regionalization GO:0003002 416 0.026
ras protein signal transduction GO:0007265 88 0.026
oxidation reduction process GO:0055114 123 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
regulation of developmental growth GO:0048638 174 0.026
tissue morphogenesis GO:0048729 297 0.026
response to extracellular stimulus GO:0009991 116 0.026
response to transition metal nanoparticle GO:1990267 9 0.025
open tracheal system development GO:0007424 204 0.025
negative regulation of cell communication GO:0010648 223 0.025
regulation of catalytic activity GO:0050790 185 0.025
g protein coupled receptor signaling pathway GO:0007186 136 0.025
monocarboxylic acid metabolic process GO:0032787 29 0.025
epithelial cell differentiation GO:0030855 322 0.025
sensory perception GO:0007600 196 0.025
endocytosis GO:0006897 310 0.025
programmed cell death GO:0012501 257 0.025
negative regulation of gene expression GO:0010629 387 0.025
male gamete generation GO:0048232 201 0.024
response to temperature stimulus GO:0009266 106 0.024
negative regulation of signal transduction GO:0009968 206 0.024
positive regulation of response to stimulus GO:0048584 323 0.024
death GO:0016265 284 0.024
negative regulation of response to stimulus GO:0048585 258 0.023
cellular response to heat GO:0034605 24 0.023
circulatory system process GO:0003013 37 0.023
neuron recognition GO:0008038 101 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
establishment of localization in cell GO:0051649 402 0.023
hormone biosynthetic process GO:0042446 20 0.023
epidermis development GO:0008544 65 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
response to copper ion GO:0046688 4 0.023
hormone catabolic process GO:0042447 3 0.023
phagocytosis GO:0006909 215 0.023
alcohol biosynthetic process GO:0046165 14 0.023
actin filament based process GO:0030029 220 0.023
response to nutrient levels GO:0031667 114 0.023
response to oxidative stress GO:0006979 86 0.023
small gtpase mediated signal transduction GO:0007264 88 0.023
regulation of cellular amine metabolic process GO:0033238 3 0.023
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.023
regulation of cellular ketone metabolic process GO:0010565 3 0.023
regulation of hormone levels GO:0010817 40 0.022
purine nucleoside metabolic process GO:0042278 127 0.022
cellular chemical homeostasis GO:0055082 40 0.022
acetylcholine metabolic process GO:0008291 2 0.022
regulation of tube size GO:0035150 46 0.022
ovarian follicle cell migration GO:0007297 121 0.022
regulation of molecular function GO:0065009 217 0.022
response to inorganic substance GO:0010035 44 0.022
steroid metabolic process GO:0008202 20 0.022
acetate ester metabolic process GO:1900619 2 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
regulation of cellular amino acid metabolic process GO:0006521 0 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
morphogenesis of an epithelium GO:0002009 276 0.022
cellular response to abiotic stimulus GO:0071214 58 0.021
ameboidal type cell migration GO:0001667 151 0.021
biological adhesion GO:0022610 138 0.021
neurotransmitter catabolic process GO:0042135 1 0.021
regulation of nervous system development GO:0051960 248 0.021
innate immune response GO:0045087 144 0.021
peptide metabolic process GO:0006518 80 0.021
organic cyclic compound catabolic process GO:1901361 168 0.021
eye morphogenesis GO:0048592 260 0.020
purine containing compound metabolic process GO:0072521 155 0.020
female meiosis chromosome segregation GO:0016321 33 0.020
regulation of blood circulation GO:1903522 21 0.020
macromolecule catabolic process GO:0009057 161 0.020
meiotic cell cycle GO:0051321 171 0.020
chemotaxis GO:0006935 249 0.020
phosphatidic acid metabolic process GO:0046473 1 0.020
multi multicellular organism process GO:0044706 123 0.020
neuron projection guidance GO:0097485 241 0.020
regulation of transport GO:0051049 181 0.020
nucleoside phosphate metabolic process GO:0006753 162 0.020
choline metabolic process GO:0019695 1 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
negative regulation of signaling GO:0023057 219 0.019
cell cell junction organization GO:0045216 55 0.019
response to light stimulus GO:0009416 124 0.019
organic substance transport GO:0071702 257 0.019
localization of cell GO:0051674 257 0.019
sterol metabolic process GO:0016125 12 0.019
regulation of response to stress GO:0080134 200 0.019
cell motility GO:0048870 251 0.019
cell recognition GO:0008037 102 0.019
embryonic development via the syncytial blastoderm GO:0001700 148 0.019
regulation of mapk cascade GO:0043408 92 0.019
ion transmembrane transport GO:0034220 122 0.019
response to alcohol GO:0097305 95 0.018
nucleobase containing small molecule metabolic process GO:0055086 174 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
positive regulation of phosphorus metabolic process GO:0010562 139 0.018
axon guidance GO:0007411 233 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
immune effector process GO:0002252 98 0.018
ecdysone metabolic process GO:0008205 11 0.018
neurotransmitter metabolic process GO:0042133 2 0.018
chromosome segregation GO:0007059 157 0.018
carbohydrate derivative catabolic process GO:1901136 118 0.018
response to heat GO:0009408 63 0.018
regulation of organelle organization GO:0033043 196 0.018
regulation of immune system process GO:0002682 176 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.018
tissue migration GO:0090130 155 0.018
lipid catabolic process GO:0016042 21 0.018
response to radiation GO:0009314 155 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
nucleoside metabolic process GO:0009116 127 0.018
actin cytoskeleton organization GO:0030036 206 0.018
spermatogenesis GO:0007283 200 0.018
cell adhesion GO:0007155 136 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
aromatic compound catabolic process GO:0019439 166 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.017
epithelial cell development GO:0002064 274 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
cellular protein localization GO:0034613 160 0.017
cation homeostasis GO:0055080 51 0.017
fatty acid metabolic process GO:0006631 20 0.017
synaptic transmission GO:0007268 288 0.017
cellular response to biotic stimulus GO:0071216 4 0.017
response to ethanol GO:0045471 59 0.016
metal ion transport GO:0030001 74 0.016
immune response activating signal transduction GO:0002757 2 0.016
mapk cascade GO:0000165 107 0.016
exocrine system development GO:0035272 162 0.016
tergite morphogenesis GO:0007490 1 0.016
nucleoside catabolic process GO:0009164 112 0.016
skin development GO:0043588 65 0.016
organelle assembly GO:0070925 198 0.016
compound eye morphogenesis GO:0001745 249 0.016
regulation of neurogenesis GO:0050767 158 0.016
metal ion homeostasis GO:0055065 44 0.016
meiotic nuclear division GO:0007126 151 0.016
tube development GO:0035295 244 0.016
pigment metabolic process GO:0042440 84 0.016
antimicrobial humoral response GO:0019730 99 0.016
protein phosphorylation GO:0006468 169 0.016
organonitrogen compound biosynthetic process GO:1901566 117 0.016
sterol homeostasis GO:0055092 4 0.016
cellular response to lipopolysaccharide GO:0071222 3 0.016
ecdysone biosynthetic process GO:0006697 9 0.015
regulation of cell cycle GO:0051726 291 0.015
positive regulation of molecular function GO:0044093 136 0.015
lipid localization GO:0010876 54 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
cuticle development GO:0042335 86 0.015
macromolecular complex assembly GO:0065003 256 0.015
positive regulation of cell motility GO:2000147 3 0.015
spindle organization GO:0007051 253 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
regulation of neuron projection development GO:0010975 69 0.015
positive regulation of cell migration GO:0030335 2 0.015
response to paraquat GO:1901562 4 0.015
digestive tract development GO:0048565 149 0.015
central nervous system development GO:0007417 201 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
mating behavior GO:0007617 106 0.014
epithelial cell migration GO:0010631 148 0.014
axon development GO:0061564 297 0.014
salivary gland development GO:0007431 162 0.014
response to lipopolysaccharide GO:0032496 4 0.014
positive regulation of immune system process GO:0002684 68 0.014
cation transport GO:0006812 110 0.014
signal transduction by phosphorylation GO:0023014 107 0.014
protein localization GO:0008104 284 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of catabolic process GO:0009894 170 0.014
choline catabolic process GO:0042426 1 0.014
regulation of phosphorylation GO:0042325 147 0.014
terpenoid metabolic process GO:0006721 7 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.014
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.014
nucleotide metabolic process GO:0009117 161 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
negative regulation of cellular component organization GO:0051129 108 0.014
body morphogenesis GO:0010171 2 0.014
transmembrane transport GO:0055085 139 0.014
embryonic morphogenesis GO:0048598 206 0.014
regulation of apoptotic process GO:0042981 130 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
proteolysis GO:0006508 192 0.014
cellular response to radiation GO:0071478 52 0.014
response to monosaccharide GO:0034284 4 0.013
cellular response to molecule of bacterial origin GO:0071219 3 0.013
maintenance of location GO:0051235 73 0.013
multicellular organismal aging GO:0010259 140 0.013
actin filament organization GO:0007015 126 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
regulation of programmed cell death GO:0043067 152 0.013
digestive system development GO:0055123 149 0.013
regulation of cell differentiation GO:0045595 302 0.013
dna metabolic process GO:0006259 227 0.013
regulation of cell proliferation GO:0042127 163 0.013
transition metal ion homeostasis GO:0055076 17 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
triglyceride homeostasis GO:0070328 18 0.013
response to uv GO:0009411 24 0.013
embryo development ending in birth or egg hatching GO:0009792 152 0.013
regulation of localization GO:0032879 275 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.013
sterol biosynthetic process GO:0016126 9 0.013
cellular response to oxidative stress GO:0034599 28 0.013
regulation of system process GO:0044057 36 0.013
toxin metabolic process GO:0009404 2 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
blood circulation GO:0008015 26 0.013
connective tissue development GO:0061448 3 0.013
autophagic cell death GO:0048102 83 0.013
chromosome organization GO:0051276 360 0.013
respiratory system development GO:0060541 213 0.013
mating GO:0007618 120 0.013
compound eye development GO:0048749 307 0.013
regulation of ras protein signal transduction GO:0046578 93 0.012
cell migration GO:0016477 238 0.012
response to wounding GO:0009611 94 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
glycosyl compound catabolic process GO:1901658 112 0.012
regulation of cell development GO:0060284 215 0.012
heterocycle catabolic process GO:0046700 166 0.012
ion transport GO:0006811 145 0.012
sensory organ morphogenesis GO:0090596 260 0.012
cellular metal ion homeostasis GO:0006875 31 0.012
telencephalon development GO:0021537 2 0.012
cell maturation GO:0048469 144 0.012
developmental maturation GO:0021700 172 0.012
mitotic nuclear division GO:0007067 213 0.012
cellular response to starvation GO:0009267 61 0.012
regulation of cell death GO:0010941 173 0.012
cellular biogenic amine catabolic process GO:0042402 1 0.012
male mating behavior GO:0060179 70 0.012
cellular cation homeostasis GO:0030003 38 0.012
transition metal ion transport GO:0000041 16 0.012
negative regulation of biosynthetic process GO:0009890 277 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
endomembrane system organization GO:0010256 119 0.012
cellular response to organic substance GO:0071310 132 0.012
developmental programmed cell death GO:0010623 138 0.011
response to caffeine GO:0031000 12 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
apoptotic process GO:0006915 159 0.011
mrna metabolic process GO:0016071 124 0.011
rho protein signal transduction GO:0007266 14 0.011
dorsal closure GO:0007391 79 0.011
sensory perception of smell GO:0007608 80 0.011
leg disc development GO:0035218 92 0.011
eye development GO:0001654 323 0.011
axis specification GO:0009798 167 0.011
positive regulation of developmental process GO:0051094 143 0.011
dendrite morphogenesis GO:0048813 199 0.011
gland development GO:0048732 191 0.011
response to endogenous stimulus GO:0009719 119 0.011
negative regulation of developmental process GO:0051093 201 0.011
chitin based cuticle development GO:0040003 49 0.011
wound healing GO:0042060 75 0.011
glycerolipid metabolic process GO:0046486 34 0.011
kidney development GO:0001822 3 0.011
regulation of immune response GO:0050776 118 0.011
establishment of protein localization GO:0045184 163 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
cation transmembrane transport GO:0098655 88 0.011
ovarian follicle cell development GO:0030707 248 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
meiotic cell cycle process GO:1903046 132 0.011
response to hexose GO:0009746 3 0.011
neuropeptide signaling pathway GO:0007218 45 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
response to purine containing compound GO:0014074 12 0.011
cell junction assembly GO:0034329 42 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
purine ribonucleotide metabolic process GO:0009150 145 0.011
determination of adult lifespan GO:0008340 137 0.010
cellular component assembly involved in morphogenesis GO:0010927 151 0.010
mitotic spindle organization GO:0007052 220 0.010
dendrite development GO:0016358 204 0.010
gland morphogenesis GO:0022612 145 0.010
drinking behavior GO:0042756 2 0.010
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.010
purine nucleoside catabolic process GO:0006152 112 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
oxidoreduction coenzyme metabolic process GO:0006733 2 0.010
camera type eye development GO:0043010 4 0.010
positive regulation of cellular component organization GO:0051130 156 0.010
purine nucleotide metabolic process GO:0006163 146 0.010
organic hydroxy compound catabolic process GO:1901616 4 0.010
synaptic target recognition GO:0008039 45 0.010
segmentation GO:0035282 207 0.010
phosphatidylinositol mediated signaling GO:0048015 4 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
amide biosynthetic process GO:0043604 42 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
regulation of vesicle mediated transport GO:0060627 59 0.010
protein complex biogenesis GO:0070271 201 0.010
purine containing compound catabolic process GO:0072523 112 0.010

TotA disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
hypertension DOID:10763 0 0.179
artery disease DOID:0050828 0 0.179
disease of anatomical entity DOID:7 0 0.179
vascular disease DOID:178 0 0.179
essential hypertension DOID:10825 0 0.179
cardiovascular system disease DOID:1287 0 0.179
disease of metabolism DOID:0014667 0 0.019
nervous system disease DOID:863 0 0.015
acquired metabolic disease DOID:0060158 0 0.011
inherited metabolic disorder DOID:655 0 0.011
musculoskeletal system disease DOID:17 0 0.010