Drosophila melanogaster

49 known processes

Prx5 (Dmel_CG7217)

Peroxiredoxin 5

(Aliases: dprx5,Dmel\CG7217,CG7217,dPrx5,CG 7217,CG 32920,CG32920)

Prx5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to reactive oxygen species GO:0000302 24 0.965
Human
aging GO:0007568 143 0.822
determination of adult lifespan GO:0008340 137 0.796
response to hydrogen peroxide GO:0042542 11 0.736
Human
response to oxidative stress GO:0006979 86 0.723
cellular response to reactive oxygen species GO:0034614 14 0.694
Human
multicellular organismal aging GO:0010259 140 0.575
response to other organism GO:0051707 293 0.517
defense response to bacterium GO:0042742 178 0.433
catabolic process GO:0009056 409 0.401
Human
response to biotic stimulus GO:0009607 294 0.361
hydrogen peroxide catabolic process GO:0042744 6 0.319
Human
response to bacterium GO:0009617 198 0.289
defense response to other organism GO:0098542 225 0.272
response to external biotic stimulus GO:0043207 293 0.263
response to oxygen containing compound GO:1901700 200 0.253
Human
cell motility GO:0048870 251 0.222
response to oxygen radical GO:0000305 3 0.219
cellular catabolic process GO:0044248 372 0.195
Human
cellular amide metabolic process GO:0043603 80 0.172
negative regulation of signal transduction GO:0009968 206 0.170
regulation of programmed cell death GO:0043067 152 0.167
cell death GO:0008219 279 0.164
defense response GO:0006952 300 0.154
intracellular signal transduction GO:0035556 300 0.144
regulation of intracellular signal transduction GO:1902531 236 0.141
immune system process GO:0002376 347 0.134
regulation of cell death GO:0010941 173 0.131
organonitrogen compound metabolic process GO:1901564 318 0.115
Human
purine containing compound metabolic process GO:0072521 155 0.110
nucleobase containing small molecule metabolic process GO:0055086 174 0.109
Human
cellular amino acid metabolic process GO:0006520 61 0.105
negative regulation of response to stimulus GO:0048585 258 0.101
homeostatic process GO:0042592 199 0.101
negative regulation of developmental process GO:0051093 201 0.101
positive regulation of cell communication GO:0010647 250 0.095
response to organic substance GO:0010033 284 0.092
small molecule metabolic process GO:0044281 305 0.091
Human
regulation of protein metabolic process GO:0051246 256 0.090
Human
cellular response to chemical stimulus GO:0070887 199 0.088
Human
apoptotic signaling pathway GO:0097190 27 0.087
oxidation reduction process GO:0055114 123 0.085
Human
regulation of catabolic process GO:0009894 170 0.081
organic substance catabolic process GO:1901575 308 0.080
apoptotic process GO:0006915 159 0.077
inorganic cation transmembrane transport GO:0098662 61 0.076
response to starvation GO:0042594 97 0.075
negative regulation of cell communication GO:0010648 223 0.074
negative regulation of cell death GO:0060548 81 0.073
ribose phosphate metabolic process GO:0019693 145 0.069
cellular response to dna damage stimulus GO:0006974 223 0.068
positive regulation of signaling GO:0023056 243 0.064
organophosphate metabolic process GO:0019637 195 0.061
Human
cell adhesion GO:0007155 136 0.060
carbohydrate derivative metabolic process GO:1901135 217 0.060
death GO:0016265 284 0.059
ribonucleotide metabolic process GO:0009259 145 0.058
defense response to gram negative bacterium GO:0050829 94 0.054
purine nucleoside metabolic process GO:0042278 127 0.054
regulation of cellular protein metabolic process GO:0032268 243 0.053
Human
negative regulation of signaling GO:0023057 219 0.051
protein complex assembly GO:0006461 200 0.050
anatomical structure homeostasis GO:0060249 97 0.050
Human
cellular response to nutrient levels GO:0031669 62 0.048
cellular response to external stimulus GO:0071496 66 0.048
purine ribonucleotide metabolic process GO:0009150 145 0.044
protein complex biogenesis GO:0070271 201 0.043
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.043
endocytosis GO:0006897 310 0.043
programmed cell death GO:0012501 257 0.041
regulation of catalytic activity GO:0050790 185 0.041
Human
single organism catabolic process GO:0044712 228 0.041
Human
response to organic cyclic compound GO:0014070 89 0.040
positive regulation of signal transduction GO:0009967 223 0.040
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.040
cellular amine metabolic process GO:0044106 12 0.039
purine ribonucleoside metabolic process GO:0046128 127 0.038
ribonucleoside metabolic process GO:0009119 127 0.038
cellular response to oxidative stress GO:0034599 28 0.038
Human
positive regulation of response to stimulus GO:0048584 323 0.037
purine nucleotide metabolic process GO:0006163 146 0.037
localization of cell GO:0051674 257 0.036
intrinsic apoptotic signaling pathway GO:0097193 16 0.036
regulation of proteolysis GO:0030162 87 0.034
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.034
nucleoside phosphate metabolic process GO:0006753 162 0.033
Human
immune response GO:0006955 246 0.032
ribonucleoside triphosphate metabolic process GO:0009199 119 0.030
reproductive structure development GO:0048608 74 0.030
purine nucleoside triphosphate metabolic process GO:0009144 119 0.029
regulation of cell differentiation GO:0045595 302 0.029
response to extracellular stimulus GO:0009991 116 0.028
negative regulation of programmed cell death GO:0043069 72 0.028
organonitrogen compound catabolic process GO:1901565 128 0.028
organonitrogen compound biosynthetic process GO:1901566 117 0.026
phosphorylation GO:0016310 294 0.026
response to heat GO:0009408 63 0.026
regulation of apoptotic process GO:0042981 130 0.025
innate immune response GO:0045087 144 0.025
nucleotide metabolic process GO:0009117 161 0.025
Human
embryo development ending in birth or egg hatching GO:0009792 152 0.024
negative regulation of purine nucleotide catabolic process GO:0033122 1 0.024
macromolecular complex assembly GO:0065003 256 0.024
positive regulation of apoptotic signaling pathway GO:2001235 4 0.024
response to lipopolysaccharide GO:0032496 4 0.024
regulation of cell cycle GO:0051726 291 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.023
spinal cord development GO:0021510 1 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
single organism behavior GO:0044708 391 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
glycosyl compound metabolic process GO:1901657 127 0.023
negative regulation of apoptotic process GO:0043066 63 0.022
oxoacid metabolic process GO:0043436 103 0.021
larval development GO:0002164 104 0.021
inorganic ion transmembrane transport GO:0098660 73 0.021
regulation of hydrolase activity GO:0051336 97 0.021
Human
purine nucleoside biosynthetic process GO:0042451 3 0.021
nucleobase containing compound catabolic process GO:0034655 165 0.020
chemical homeostasis GO:0048878 92 0.020
aromatic compound catabolic process GO:0019439 166 0.020
positive regulation of endopeptidase activity GO:0010950 26 0.020
growth GO:0040007 359 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
ribonucleoside monophosphate metabolic process GO:0009161 51 0.019
cellular response to extracellular stimulus GO:0031668 64 0.019
mitochondrion organization GO:0007005 65 0.019
energy derivation by oxidation of organic compounds GO:0015980 32 0.019
nucleoside phosphate catabolic process GO:1901292 110 0.018
organelle inheritance GO:0048308 2 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
regulation of endopeptidase activity GO:0052548 36 0.018
Human
establishment of localization in cell GO:0051649 402 0.018
reproductive system development GO:0061458 74 0.018
response to organonitrogen compound GO:0010243 75 0.018
regulation of response to external stimulus GO:0032101 115 0.017
maintenance of location GO:0051235 73 0.017
mitochondrial membrane organization GO:0007006 3 0.017
peptide metabolic process GO:0006518 80 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
amine metabolic process GO:0009308 12 0.017
negative regulation of cellular metabolic process GO:0031324 382 0.016
Human
organelle fission GO:0048285 340 0.016
regulation of peptidase activity GO:0052547 39 0.016
Human
regulation of growth GO:0040008 233 0.016
cellular response to oxygen containing compound GO:1901701 79 0.016
Human
epithelial cell differentiation GO:0030855 322 0.016
hematopoietic stem cell differentiation GO:0060218 1 0.016
positive regulation of cell death GO:0010942 69 0.015
humoral immune response GO:0006959 117 0.015
cellular ketone metabolic process GO:0042180 24 0.015
rna processing GO:0006396 147 0.015
spermatogenesis GO:0007283 200 0.015
cation transmembrane transport GO:0098655 88 0.015
response to superoxide GO:0000303 3 0.015
regulation of phosphate metabolic process GO:0019220 210 0.014
protein modification process GO:0036211 438 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
response to wounding GO:0009611 94 0.014
molting cycle GO:0042303 56 0.014
nucleoside metabolic process GO:0009116 127 0.014
respiratory electron transport chain GO:0022904 11 0.014
response to nutrient levels GO:0031667 114 0.014
protein phosphorylation GO:0006468 169 0.014
stem cell proliferation GO:0072089 88 0.013
positive regulation of proteolysis GO:0045862 52 0.013
regulation of atp catabolic process GO:1903289 4 0.013
protein homooligomerization GO:0051260 7 0.013
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.013
sex differentiation GO:0007548 81 0.013
phagocytosis GO:0006909 215 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
cellular protein modification process GO:0006464 438 0.013
ion transport GO:0006811 145 0.013
cell growth GO:0016049 108 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
nuclear division GO:0000280 332 0.013
regulation of autophagy GO:0010506 62 0.012
central nervous system development GO:0007417 201 0.012
response to nitrogen compound GO:1901698 90 0.012
regulation of protein modification process GO:0031399 112 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
positive regulation of biosynthetic process GO:0009891 316 0.011
Human
vesicle mediated transport GO:0016192 381 0.011
regulation of phosphatase activity GO:0010921 3 0.011
regulation of membrane potential GO:0042391 35 0.011
regulation of apoptotic signaling pathway GO:2001233 10 0.011
regulation of lipid metabolic process GO:0019216 15 0.011
appendage morphogenesis GO:0035107 397 0.011
cellular response to hydrogen peroxide GO:0070301 7 0.011
Human
wound healing GO:0042060 75 0.011
negative regulation of gene expression GO:0010629 387 0.011
Human
regulation of jak stat cascade GO:0046425 43 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
meiotic nuclear division GO:0007126 151 0.011
regulation of phosphorylation GO:0042325 147 0.011
negative regulation of signal transduction by p53 class mediator GO:1901797 1 0.011
cell chemotaxis involved in malpighian tubule morphogenesis GO:0061352 3 0.011
intermediate filament cytoskeleton organization GO:0045104 1 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
regulation of cysteine type endopeptidase activity GO:2000116 27 0.011
Human
response to temperature stimulus GO:0009266 106 0.011
endomembrane system organization GO:0010256 119 0.010
regulation of atpase activity GO:0043462 4 0.010
gland development GO:0048732 191 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
developmental programmed cell death GO:0010623 138 0.010
cation transport GO:0006812 110 0.010

Prx5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
chromosomal disease DOID:0080014 0 0.032
gonadal dysgenesis DOID:14447 0 0.032
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011