Drosophila melanogaster

55 known processes

Lac (Dmel_CG12369)

Lachesin

(Aliases: Dmel\CG12369,l(2)k11012b,CT24921,l(2)k11012,CG12369,bulb,lac)

Lac biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cell junction assembly GO:0034329 42 0.429
cell cell junction assembly GO:0007043 38 0.415
cell junction organization GO:0034330 57 0.375
neuron recognition GO:0008038 101 0.339
heart morphogenesis GO:0003007 32 0.272
biological adhesion GO:0022610 138 0.266
sensory organ morphogenesis GO:0090596 260 0.215
apical junction assembly GO:0043297 32 0.203
cell adhesion GO:0007155 136 0.193
axon guidance GO:0007411 233 0.186
taxis GO:0042330 304 0.169
septate junction assembly GO:0019991 26 0.168
tissue morphogenesis GO:0048729 297 0.166
cell recognition GO:0008037 102 0.163
gliogenesis GO:0042063 80 0.160
synaptic transmission GO:0007268 288 0.158
endocytosis GO:0006897 310 0.152
cell cell junction organization GO:0045216 55 0.135
regulation of tube architecture open tracheal system GO:0035152 68 0.126
positive regulation of cellular component organization GO:0051130 156 0.126
regulation of multicellular organismal development GO:2000026 414 0.122
regulation of defense response to bacterium GO:1900424 30 0.120
respiratory system development GO:0060541 213 0.114
embryonic morphogenesis GO:0048598 206 0.109
positive regulation of gene expression GO:0010628 290 0.107
cell migration GO:0016477 238 0.107
neuron projection guidance GO:0097485 241 0.106
single organism behavior GO:0044708 391 0.105
defense response to other organism GO:0098542 225 0.101
cell adhesion involved in heart morphogenesis GO:0061343 12 0.098
lateral inhibition GO:0046331 206 0.097
regulation of cell cycle GO:0051726 291 0.095
body morphogenesis GO:0010171 2 0.094
establishment of localization in cell GO:0051649 402 0.094
neurological system process GO:0050877 358 0.092
embryo development ending in birth or egg hatching GO:0009792 152 0.091
circulatory system development GO:0072359 82 0.090
cell proliferation GO:0008283 299 0.088
regulation of cell development GO:0060284 215 0.085
epithelial cell differentiation GO:0030855 322 0.085
glial cell differentiation GO:0010001 35 0.081
homeostatic process GO:0042592 199 0.079
cardiovascular system development GO:0072358 82 0.079
nephron development GO:0072006 3 0.079
nephron morphogenesis GO:0072028 3 0.078
localization of cell GO:0051674 257 0.076
morphogenesis of an epithelium GO:0002009 276 0.075
vesicle mediated transport GO:0016192 381 0.074
imaginal disc derived appendage morphogenesis GO:0035114 395 0.072
eye development GO:0001654 323 0.069
appendage morphogenesis GO:0035107 397 0.068
chemotaxis GO:0006935 249 0.067
response to biotic stimulus GO:0009607 294 0.067
heart development GO:0007507 82 0.064
embryonic development via the syncytial blastoderm GO:0001700 148 0.063
wing disc morphogenesis GO:0007472 344 0.063
chromosome segregation GO:0007059 157 0.062
response to abiotic stimulus GO:0009628 341 0.060
centrosome organization GO:0051297 163 0.060
response to external biotic stimulus GO:0043207 293 0.060
antibacterial humoral response GO:0019731 44 0.059
developmental maturation GO:0021700 172 0.058
cell maturation GO:0048469 144 0.056
telencephalon development GO:0021537 2 0.056
regulation of cell differentiation GO:0045595 302 0.055
antimicrobial humoral response GO:0019730 99 0.055
adult behavior GO:0030534 137 0.054
axonogenesis GO:0007409 290 0.054
cytoskeleton dependent cytokinesis GO:0061640 81 0.052
motor neuron axon guidance GO:0008045 58 0.052
protein modification process GO:0036211 438 0.052
kidney epithelium development GO:0072073 3 0.052
establishment of blood brain barrier GO:0060856 16 0.051
negative regulation of multicellular organismal process GO:0051241 142 0.050
death GO:0016265 284 0.049
imaginal disc derived appendage development GO:0048737 399 0.049
cellular macromolecule localization GO:0070727 220 0.049
g protein coupled receptor signaling pathway GO:0007186 136 0.048
mitotic cytokinesis GO:0000281 50 0.048
positive regulation of signal transduction GO:0009967 223 0.047
regulation of multi organism process GO:0043900 131 0.046
defense response GO:0006952 300 0.046
regulation of response to stress GO:0080134 200 0.046
regionalization GO:0003002 416 0.045
cellular response to dna damage stimulus GO:0006974 223 0.045
protein maturation GO:0051604 71 0.044
establishment of protein localization GO:0045184 163 0.044
cognition GO:0050890 141 0.043
tube development GO:0035295 244 0.043
regulation of intracellular signal transduction GO:1902531 236 0.043
eye morphogenesis GO:0048592 260 0.042
notch signaling pathway GO:0007219 120 0.042
imaginal disc derived wing morphogenesis GO:0007476 337 0.042
negative regulation of cell development GO:0010721 62 0.041
regulation of cell substrate adhesion GO:0010810 2 0.041
positive regulation of transport GO:0051050 92 0.040
digestive system development GO:0055123 149 0.040
neuron maturation GO:0042551 31 0.040
positive regulation of macromolecule metabolic process GO:0010604 405 0.040
digestive tract development GO:0048565 149 0.040
appendage development GO:0048736 401 0.040
regulation of transport GO:0051049 181 0.039
negative regulation of signaling GO:0023057 219 0.039
regulation of cellular response to stress GO:0080135 89 0.038
phagocytosis GO:0006909 215 0.037
ameboidal type cell migration GO:0001667 151 0.036
negative regulation of signal transduction GO:0009968 206 0.036
negative regulation of cell communication GO:0010648 223 0.036
locomotory behavior GO:0007626 176 0.036
regulation of cellular protein metabolic process GO:0032268 243 0.035
response to bacterium GO:0009617 198 0.035
muscle organ development GO:0007517 127 0.034
compound eye development GO:0048749 307 0.034
protein localization GO:0008104 284 0.034
cell division GO:0051301 248 0.034
protein processing GO:0016485 68 0.034
epithelial cell development GO:0002064 274 0.033
establishment of glial blood brain barrier GO:0060857 14 0.033
single organism cell adhesion GO:0098602 47 0.033
regulation of neurogenesis GO:0050767 158 0.033
compound eye morphogenesis GO:0001745 249 0.032
positive regulation of signaling GO:0023056 243 0.032
regulation of protein metabolic process GO:0051246 256 0.032
regulation of protein modification process GO:0031399 112 0.032
phosphorylation GO:0016310 294 0.032
organonitrogen compound metabolic process GO:1901564 318 0.031
renal system development GO:0072001 72 0.031
humoral immune response GO:0006959 117 0.031
intrinsic apoptotic signaling pathway GO:0097193 16 0.031
regulation of response to external stimulus GO:0032101 115 0.031
central nervous system development GO:0007417 201 0.031
positive regulation of cellular biosynthetic process GO:0031328 316 0.030
negative regulation of response to external stimulus GO:0032102 22 0.030
regulation of defense response GO:0031347 102 0.030
small molecule metabolic process GO:0044281 305 0.030
epithelial structure maintenance GO:0010669 17 0.030
negative regulation of developmental process GO:0051093 201 0.030
regulation of intracellular protein transport GO:0033157 46 0.029
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.029
regulation of synaptic transmission GO:0050804 69 0.029
defense response to gram negative bacterium GO:0050829 94 0.029
cell motility GO:0048870 251 0.028
learning or memory GO:0007611 141 0.028
regulation of cell proliferation GO:0042127 163 0.028
positive regulation of nucleocytoplasmic transport GO:0046824 24 0.028
organic substance transport GO:0071702 257 0.028
regulation of response to biotic stimulus GO:0002831 63 0.027
nucleocytoplasmic transport GO:0006913 72 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.027
regulation of glial cell differentiation GO:0045685 1 0.027
regulation of phosphorylation GO:0042325 147 0.026
axon development GO:0061564 297 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.026
regulation of nervous system development GO:0051960 248 0.026
regulation of cell adhesion GO:0030155 27 0.026
positive regulation of protein metabolic process GO:0051247 128 0.025
positive regulation of protein localization to nucleus GO:1900182 21 0.025
protein phosphorylation GO:0006468 169 0.025
brain development GO:0007420 120 0.025
negative regulation of cell differentiation GO:0045596 143 0.024
cellular protein localization GO:0034613 160 0.024
immune system process GO:0002376 347 0.024
renal filtration cell differentiation GO:0061318 12 0.024
digestive tract morphogenesis GO:0048546 127 0.024
tube morphogenesis GO:0035239 191 0.024
open tracheal system development GO:0007424 204 0.024
regulation of localization GO:0032879 275 0.024
hindgut morphogenesis GO:0007442 58 0.023
post embryonic appendage morphogenesis GO:0035120 385 0.023
dorsal ventral pattern formation GO:0009953 133 0.023
morphogenesis of embryonic epithelium GO:0016331 94 0.023
mesenchymal cell differentiation GO:0048762 1 0.023
kidney morphogenesis GO:0060993 3 0.023
regulation of nucleocytoplasmic transport GO:0046822 35 0.022
sensory perception GO:0007600 196 0.022
intracellular signal transduction GO:0035556 300 0.022
blastoderm segmentation GO:0007350 159 0.022
negative regulation of neurogenesis GO:0050768 53 0.022
forebrain development GO:0030900 2 0.022
malpighian tubule development GO:0072002 64 0.022
positive regulation of immune system process GO:0002684 68 0.022
regulation of molecular function GO:0065009 217 0.022
positive regulation of nucleic acid templated transcription GO:1903508 266 0.021
positive regulation of cell communication GO:0010647 250 0.021
immune response GO:0006955 246 0.021
response to fungus GO:0009620 50 0.021
negative regulation of response to stimulus GO:0048585 258 0.021
head development GO:0060322 135 0.021
regulation of cellular localization GO:0060341 136 0.021
oxoacid metabolic process GO:0043436 103 0.020
innate immune response GO:0045087 144 0.020
establishment of tissue polarity GO:0007164 87 0.020
regulation of reproductive process GO:2000241 54 0.020
protein k48 linked ubiquitination GO:0070936 3 0.020
response to lipopolysaccharide GO:0032496 4 0.020
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.020
cell death GO:0008219 279 0.020
regulation of cell morphogenesis GO:0022604 163 0.020
wnt signaling pathway GO:0016055 98 0.020
regulation of neuronal synaptic plasticity GO:0048168 8 0.020
regulation of innate immune response GO:0045088 71 0.020
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.020
organelle fission GO:0048285 340 0.020
rna localization GO:0006403 115 0.020
nephron epithelium development GO:0072009 3 0.020
protein transport GO:0015031 155 0.019
positive regulation of response to stimulus GO:0048584 323 0.019
secretion by cell GO:0032940 101 0.019
chemosensory behavior GO:0007635 106 0.019
embryonic organ development GO:0048568 50 0.019
regulation of protein transport GO:0051223 57 0.019
protein localization to organelle GO:0033365 82 0.019
immune response activating signal transduction GO:0002757 2 0.019
positive regulation of developmental process GO:0051094 143 0.018
intracellular protein transport GO:0006886 104 0.018
adherens junction organization GO:0034332 27 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
regulation of organ morphogenesis GO:2000027 78 0.018
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.018
segmentation GO:0035282 207 0.018
regulation of anatomical structure morphogenesis GO:0022603 242 0.018
hemocyte differentiation GO:0042386 38 0.018
production of molecular mediator of immune response GO:0002440 46 0.018
organic acid metabolic process GO:0006082 103 0.018
programmed cell death GO:0012501 257 0.018
regulation of cell cycle process GO:0010564 181 0.018
establishment or maintenance of cell polarity GO:0007163 167 0.017
apoptotic process GO:0006915 159 0.017
adult locomotory behavior GO:0008344 76 0.017
defense response to fungus GO:0050832 48 0.017
learning GO:0007612 75 0.017
substrate adhesion dependent cell spreading GO:0034446 2 0.017
sensory perception of mechanical stimulus GO:0050954 72 0.017
rna transport GO:0050658 46 0.017
mapk cascade GO:0000165 107 0.017
kidney development GO:0001822 3 0.017
regulation of tube size GO:0035150 46 0.017
olfactory behavior GO:0042048 97 0.017
positive regulation of immune response GO:0050778 63 0.017
cellular amine metabolic process GO:0044106 12 0.016
response to organophosphorus GO:0046683 2 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
nuclear division GO:0000280 332 0.016
regulation of membrane potential GO:0042391 35 0.016
nucleotide metabolic process GO:0009117 161 0.016
regulation of anatomical structure size GO:0090066 163 0.016
limb morphogenesis GO:0035108 1 0.016
spermatogenesis GO:0007283 200 0.016
innate immune response activating signal transduction GO:0002758 2 0.016
negative regulation of multi organism process GO:0043901 29 0.016
regulation of immune effector process GO:0002697 52 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.015
response to other organism GO:0051707 293 0.015
mesenchymal cell development GO:0014031 1 0.015
regulation of gliogenesis GO:0014013 11 0.015
establishment of protein localization to organelle GO:0072594 62 0.015
protein complex assembly GO:0006461 200 0.015
response to radiation GO:0009314 155 0.015
microtubule organizing center organization GO:0031023 168 0.015
pole plasm oskar mrna localization GO:0045451 46 0.015
ovarian follicle cell development GO:0030707 248 0.015
regulation of cellular component size GO:0032535 98 0.015
regulation of immune system process GO:0002682 176 0.015
positive regulation of phosphorylation GO:0042327 87 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.014
negative regulation of protein metabolic process GO:0051248 85 0.014
salivary gland development GO:0007431 162 0.014
camera type eye development GO:0043010 4 0.014
axis specification GO:0009798 167 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
single organism cellular localization GO:1902580 180 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
muscle structure development GO:0061061 224 0.014
monovalent inorganic cation transport GO:0015672 40 0.014
cellular component assembly involved in morphogenesis GO:0010927 151 0.014
urogenital system development GO:0001655 72 0.014
dendrite development GO:0016358 204 0.014
transmembrane transport GO:0055085 139 0.014
regulation of response to dna damage stimulus GO:2001020 23 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
innate immune response in mucosa GO:0002227 2 0.014
positive regulation of cell differentiation GO:0045597 64 0.014
regulation of neural precursor cell proliferation GO:2000177 35 0.014
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
regulation of protein localization GO:0032880 76 0.014
skeletal muscle fiber development GO:0048741 3 0.014
regulation of protein localization to nucleus GO:1900180 29 0.014
regulation of growth GO:0040008 233 0.013
cellular response to sterol depletion GO:0071501 3 0.013
glial cell development GO:0021782 27 0.013
positive regulation of response to external stimulus GO:0032103 44 0.013
negative regulation of nervous system development GO:0051961 92 0.013
nephron epithelium morphogenesis GO:0072088 3 0.013
proteolysis GO:0006508 192 0.013
dorsal closure GO:0007391 79 0.013
regulation of production of molecular mediator of immune response GO:0002700 44 0.013
hematopoietic progenitor cell differentiation GO:0002244 1 0.013
peptide metabolic process GO:0006518 80 0.013
cellular amide metabolic process GO:0043603 80 0.013
regulation of establishment of protein localization GO:0070201 61 0.013
negative regulation of catalytic activity GO:0043086 42 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
ion transport GO:0006811 145 0.013
amine metabolic process GO:0009308 12 0.013
hair cell differentiation GO:0035315 47 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
cell projection assembly GO:0030031 94 0.013
cell cycle phase transition GO:0044770 140 0.013
positive regulation of protein modification process GO:0031401 58 0.013
photoreceptor cell differentiation GO:0046530 170 0.012
cellular homeostasis GO:0019725 80 0.012
regulation of endocytosis GO:0030100 37 0.012
germarium derived egg chamber formation GO:0007293 101 0.012
regulation of immune response GO:0050776 118 0.012
nitrogen compound transport GO:0071705 85 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
embryonic axis specification GO:0000578 107 0.012
macromolecular complex assembly GO:0065003 256 0.012
gland development GO:0048732 191 0.012
embryonic pattern specification GO:0009880 174 0.012
camera type eye morphogenesis GO:0048593 2 0.012
protein glycosylation GO:0006486 32 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
regulation of axonogenesis GO:0050770 32 0.012
response to light stimulus GO:0009416 124 0.012
single organismal cell cell adhesion GO:0016337 45 0.012
ras protein signal transduction GO:0007265 88 0.012
regulation of cell projection organization GO:0031344 92 0.012
hindgut development GO:0061525 58 0.012
immune effector process GO:0002252 98 0.011
cellular catabolic process GO:0044248 372 0.011
positive regulation of intracellular transport GO:0032388 42 0.011
single organism catabolic process GO:0044712 228 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
exocrine system development GO:0035272 162 0.011
organic substance catabolic process GO:1901575 308 0.011
membrane organization GO:0061024 112 0.011
ovarian follicle cell migration GO:0007297 121 0.011
defense response to bacterium GO:0042742 178 0.011
regulation of neuron differentiation GO:0045664 103 0.011
retina development in camera type eye GO:0060041 4 0.011
hindbrain development GO:0030902 2 0.011
pattern recognition receptor signaling pathway GO:0002221 2 0.011
social behavior GO:0035176 4 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.011
sister chromatid segregation GO:0000819 92 0.011
regulation of antimicrobial humoral response GO:0002759 50 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
regulation of cellular amino acid metabolic process GO:0006521 0 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
determination of adult lifespan GO:0008340 137 0.011
spinal cord development GO:0021510 1 0.011
connective tissue development GO:0061448 3 0.010
nuclear import GO:0051170 51 0.010
larval development GO:0002164 104 0.010
neuron projection regeneration GO:0031102 8 0.010
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.010
proximal distal pattern formation GO:0009954 15 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
nephron tubule development GO:0072080 3 0.010
positive regulation of multi organism process GO:0043902 40 0.010
positive regulation of protein import into nucleus GO:0042307 21 0.010
positive regulation of cell proliferation GO:0008284 47 0.010
positive regulation of cell motility GO:2000147 3 0.010
skeletal muscle organ development GO:0060538 48 0.010
nuclear transport GO:0051169 72 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010
intracellular transport GO:0046907 228 0.010
organelle localization GO:0051640 148 0.010

Lac disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.070
musculoskeletal system disease DOID:17 0 0.027
cardiovascular system disease DOID:1287 0 0.015
sensory system disease DOID:0050155 0 0.013
nervous system disease DOID:863 0 0.013