Drosophila melanogaster

0 known processes

Nle (Dmel_CG2863)

Notchless

(Aliases: Dmel\CG2863,l(2)k13714,anon-WO0026364,CG2863)

Nle biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 147 0.241
organelle assembly GO:0070925 198 0.195
Yeast
tissue morphogenesis GO:0048729 297 0.143
negative regulation of cellular metabolic process GO:0031324 382 0.135
Mouse
regulation of protein metabolic process GO:0051246 256 0.114
Mouse
regulation of multicellular organismal development GO:2000026 414 0.097
cell division GO:0051301 248 0.094
regulation of anatomical structure morphogenesis GO:0022603 242 0.086
ribosomal large subunit biogenesis GO:0042273 1 0.080
Yeast Mouse
protein modification process GO:0036211 438 0.076
catabolic process GO:0009056 409 0.073
organic substance catabolic process GO:1901575 308 0.072
phosphorylation GO:0016310 294 0.072
regulation of cellular protein metabolic process GO:0032268 243 0.069
Mouse
organelle fission GO:0048285 340 0.065
cellular component assembly involved in morphogenesis GO:0010927 151 0.061
axon development GO:0061564 297 0.052
cell motility GO:0048870 251 0.051
cellular catabolic process GO:0044248 372 0.047
macromolecular complex assembly GO:0065003 256 0.046
Yeast
positive regulation of macromolecule metabolic process GO:0010604 405 0.045
regulation of response to stress GO:0080134 200 0.045
establishment or maintenance of cell polarity GO:0007163 167 0.044
organonitrogen compound metabolic process GO:1901564 318 0.041
cell migration GO:0016477 238 0.040
cellular protein modification process GO:0006464 438 0.040
localization of cell GO:0051674 257 0.039
establishment of tissue polarity GO:0007164 87 0.038
endocytosis GO:0006897 310 0.038
Worm
response to bacterium GO:0009617 198 0.038
vesicle mediated transport GO:0016192 381 0.037
Worm
protein complex assembly GO:0006461 200 0.037
notch signaling pathway GO:0007219 120 0.037
Mouse
small molecule metabolic process GO:0044281 305 0.037
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.035
organic substance transport GO:0071702 257 0.035
cell proliferation GO:0008283 299 0.034
rrna processing GO:0006364 3 0.034
regulation of phosphate metabolic process GO:0019220 210 0.032
rna methylation GO:0001510 2 0.032
morphogenesis of an epithelium GO:0002009 276 0.032
ncrna metabolic process GO:0034660 43 0.031
protein phosphorylation GO:0006468 169 0.030
regulation of phosphorus metabolic process GO:0051174 210 0.030
regulation of molecular function GO:0065009 217 0.030
Mouse
carboxylic acid metabolic process GO:0019752 92 0.029
positive regulation of rna metabolic process GO:0051254 271 0.029
wing disc morphogenesis GO:0007472 344 0.029
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.028
larval development GO:0002164 104 0.028
Worm
negative regulation of gene expression GO:0010629 387 0.028
Mouse
positive regulation of cellular biosynthetic process GO:0031328 316 0.027
regulation of mitotic cell cycle GO:0007346 190 0.027
Mouse
regulation of transport GO:0051049 181 0.027
protein complex biogenesis GO:0070271 201 0.027
regulation of nervous system development GO:0051960 248 0.026
regulation of phosphorylation GO:0042325 147 0.026
axonogenesis GO:0007409 290 0.025
camera type eye development GO:0043010 4 0.024
nuclear export GO:0051168 24 0.024
morphogenesis of a polarized epithelium GO:0001738 93 0.024
body morphogenesis GO:0010171 2 0.024
actin cytoskeleton organization GO:0030036 206 0.024
single organism catabolic process GO:0044712 228 0.024
cytoplasmic transport GO:0016482 130 0.023
negative regulation of biosynthetic process GO:0009890 277 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
Mouse
positive regulation of gene expression GO:0010628 290 0.023
protein localization GO:0008104 284 0.022
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.022
phagocytosis GO:0006909 215 0.022
embryo development ending in birth or egg hatching GO:0009792 152 0.021
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
ribose phosphate metabolic process GO:0019693 145 0.021
protein prenylation GO:0018342 3 0.021
regulation of programmed cell death GO:0043067 152 0.020
Mouse
negative regulation of rna biosynthetic process GO:1902679 240 0.020
actin filament based process GO:0030029 220 0.020
defense response to bacterium GO:0042742 178 0.020
regulation of protein modification process GO:0031399 112 0.020
dendrite development GO:0016358 204 0.019
chromosome organization GO:0051276 360 0.019
regulation of cell development GO:0060284 215 0.019
regulation of organelle organization GO:0033043 196 0.019
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.019
positive regulation of cell cycle process GO:0090068 28 0.019
hindbrain development GO:0030902 2 0.019
organic acid metabolic process GO:0006082 103 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.018
negative regulation of rna metabolic process GO:0051253 251 0.018
establishment of protein localization GO:0045184 163 0.018
epidermal cell differentiation GO:0009913 51 0.018
oxidation reduction process GO:0055114 123 0.018
regulation of cell division GO:0051302 72 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
Yeast
macromolecule catabolic process GO:0009057 161 0.018
neuromuscular junction development GO:0007528 149 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
organelle localization GO:0051640 148 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
skeletal muscle fiber development GO:0048741 3 0.018
cellular amino acid metabolic process GO:0006520 61 0.017
positive regulation of cell communication GO:0010647 250 0.017
Mouse
nuclear division GO:0000280 332 0.017
purine containing compound catabolic process GO:0072523 112 0.017
positive regulation of histone deacetylation GO:0031065 2 0.017
snrna metabolic process GO:0016073 14 0.017
amine metabolic process GO:0009308 12 0.017
oxoacid metabolic process GO:0043436 103 0.016
establishment of localization in cell GO:0051649 402 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
post embryonic appendage morphogenesis GO:0035120 385 0.016
positive regulation of multicellular organismal process GO:0051240 143 0.016
protein transport GO:0015031 155 0.016
regulation of cellular component size GO:0032535 98 0.016
maintenance of protein location GO:0045185 28 0.016
response to external biotic stimulus GO:0043207 293 0.016
defense response GO:0006952 300 0.016
response to other organism GO:0051707 293 0.015
aromatic compound catabolic process GO:0019439 166 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
membrane organization GO:0061024 112 0.015
dendrite morphogenesis GO:0048813 199 0.015
cellular macromolecule localization GO:0070727 220 0.015
ncrna processing GO:0034470 30 0.015
trna modification GO:0006400 2 0.015
establishment of planar polarity GO:0001736 87 0.015
kidney development GO:0001822 3 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
nucleotide metabolic process GO:0009117 161 0.015
ion transport GO:0006811 145 0.015
establishment of cell polarity GO:0030010 40 0.015
single organism intracellular transport GO:1902582 207 0.015
regulation of neurogenesis GO:0050767 158 0.014
taxis GO:0042330 304 0.014
epidermis development GO:0008544 65 0.014
developmental growth GO:0048589 280 0.014
appendage morphogenesis GO:0035107 397 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
positive regulation of rna biosynthetic process GO:1902680 266 0.014
regulation of cell cycle process GO:0010564 181 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
regulation of immune response GO:0050776 118 0.014
epithelial cell differentiation GO:0030855 322 0.014
regulation of cellular component biogenesis GO:0044087 201 0.013
nephron morphogenesis GO:0072028 3 0.013
organic cyclic compound catabolic process GO:1901361 168 0.013
ribonucleoprotein complex biogenesis GO:0022613 31 0.013
Yeast Mouse
golgi organization GO:0007030 66 0.013
regulation of protein kinase activity GO:0045859 51 0.013
regulation of catalytic activity GO:0050790 185 0.013
Mouse
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.013
actin filament organization GO:0007015 126 0.013
regulation of localization GO:0032879 275 0.013
digestive system development GO:0055123 149 0.013
cellular protein complex disassembly GO:0043624 35 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
nuclear rna surveillance GO:0071027 3 0.013
organophosphate metabolic process GO:0019637 195 0.013
regulation of transferase activity GO:0051338 58 0.013
hair cell differentiation GO:0035315 47 0.013
heterocycle catabolic process GO:0046700 166 0.013
positive regulation of molecular function GO:0044093 136 0.013
rna localization GO:0006403 115 0.013
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
regulation of cellular localization GO:0060341 136 0.012
positive regulation of protein deacetylation GO:0090312 2 0.012
rna 3 end processing GO:0031123 45 0.012
atp metabolic process GO:0046034 49 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
regulation of immune system process GO:0002682 176 0.012
protein complex disassembly GO:0043241 36 0.012
regulation of cell morphogenesis GO:0022604 163 0.012
chemotaxis GO:0006935 249 0.012
endomembrane system organization GO:0010256 119 0.012
nucleobase containing small molecule metabolic process GO:0055086 174 0.012
nucleoside phosphate metabolic process GO:0006753 162 0.012
cation transmembrane transport GO:0098655 88 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
cation transport GO:0006812 110 0.011
regulation of protein depolymerization GO:1901879 27 0.011
cell cycle phase transition GO:0044770 140 0.011
regulation of histone deacetylation GO:0031063 2 0.011
nucleocytoplasmic transport GO:0006913 72 0.011
striated muscle myosin thick filament assembly GO:0071688 3 0.011
regulation of embryonic development GO:0045995 68 0.011
regulation of mrna splicing via spliceosome GO:0048024 64 0.011
cell death GO:0008219 279 0.011
Mouse
immune system process GO:0002376 347 0.011
striated muscle cell differentiation GO:0051146 90 0.011
purine containing compound metabolic process GO:0072521 155 0.011
somatic stem cell division GO:0048103 37 0.011
regulation of cellular response to stress GO:0080135 89 0.011
gliogenesis GO:0042063 80 0.011
nucleoside catabolic process GO:0009164 112 0.011
multicellular organismal reproductive behavior GO:0033057 110 0.011
regulation of protein phosphorylation GO:0001932 64 0.011
snrna 3 end processing GO:0034472 14 0.011
trna processing GO:0008033 3 0.010
regulation of multi organism process GO:0043900 131 0.010
negative regulation of epithelial cell proliferation GO:0050680 4 0.010
positive regulation of transcription dna templated GO:0045893 266 0.010
positive regulation of signal transduction GO:0009967 223 0.010
Mouse
positive regulation of developmental process GO:0051094 143 0.010
purine nucleoside monophosphate metabolic process GO:0009126 50 0.010

Nle disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.034
nervous system disease DOID:863 0 0.020
integumentary system disease DOID:16 0 0.017