Drosophila melanogaster

37 known processes

Prestin (Dmel_CG5485)

CG5485 gene product from transcript CG5485-RA

(Aliases: Dmel\CG5485,CG5485,dpres)

Prestin biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
l amino acid import GO:0043092 2 0.097
response to abiotic stimulus GO:0009628 341 0.089
l glutamate import GO:0051938 1 0.064
sodium dependent phosphate transport GO:0044341 2 0.054
organonitrogen compound metabolic process GO:1901564 318 0.050
growth GO:0040007 359 0.044
organic substance transport GO:0071702 257 0.044
homeostatic process GO:0042592 199 0.044
response to light stimulus GO:0009416 124 0.043
cellular catabolic process GO:0044248 372 0.042
defense response GO:0006952 300 0.042
endocytosis GO:0006897 310 0.041
catabolic process GO:0009056 409 0.041
small molecule metabolic process GO:0044281 305 0.041
ion transport GO:0006811 145 0.040
organic substance catabolic process GO:1901575 308 0.040
regionalization GO:0003002 416 0.040
single organism biosynthetic process GO:0044711 206 0.039
phosphate ion transport GO:0006817 4 0.039
programmed cell death GO:0012501 257 0.036
vesicle mediated transport GO:0016192 381 0.036
response to lipopolysaccharide GO:0032496 4 0.036
regulation of localization GO:0032879 275 0.035
positive regulation of signaling GO:0023056 243 0.035
response to radiation GO:0009314 155 0.035
response to external biotic stimulus GO:0043207 293 0.034
kidney development GO:0001822 3 0.034
response to hexose GO:0009746 3 0.032
protein modification process GO:0036211 438 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
death GO:0016265 284 0.030
chemical homeostasis GO:0048878 92 0.029
neurological system process GO:0050877 358 0.028
transcription from rna polymerase ii promoter GO:0006366 368 0.028
glutamine metabolic process GO:0006541 4 0.028
androgen metabolic process GO:0008209 1 0.028
oxoacid metabolic process GO:0043436 103 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
positive regulation of cell communication GO:0010647 250 0.027
response to glucose GO:0009749 2 0.027
response to bacterium GO:0009617 198 0.027
protein complex biogenesis GO:0070271 201 0.027
response to biotic stimulus GO:0009607 294 0.027
developmental pigmentation GO:0048066 68 0.027
localization of cell GO:0051674 257 0.026
cell death GO:0008219 279 0.026
response to other organism GO:0051707 293 0.026
immune system process GO:0002376 347 0.026
cellular protein modification process GO:0006464 438 0.026
response to oxygen containing compound GO:1901700 200 0.025
body morphogenesis GO:0010171 2 0.025
detection of stimulus GO:0051606 156 0.025
phagocytosis GO:0006909 215 0.024
positive regulation of cell migration GO:0030335 2 0.024
response to monosaccharide GO:0034284 4 0.024
epithelial cell differentiation GO:0030855 322 0.024
imaginal disc derived appendage development GO:0048737 399 0.023
anion transport GO:0006820 41 0.023
intracellular signal transduction GO:0035556 300 0.023
organic acid metabolic process GO:0006082 103 0.023
regulation of immune system process GO:0002682 176 0.023
aromatic compound catabolic process GO:0019439 166 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
secretion GO:0046903 109 0.023
detection of abiotic stimulus GO:0009582 66 0.023
ion transmembrane transport GO:0034220 122 0.022
cellular lipid metabolic process GO:0044255 83 0.022
positive regulation of cell motility GO:2000147 3 0.022
synaptic transmission GO:0007268 288 0.022
cellular response to hexose stimulus GO:0071331 1 0.022
open tracheal system development GO:0007424 204 0.022
cation transport GO:0006812 110 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
regulation of cell death GO:0010941 173 0.022
developmental growth GO:0048589 280 0.022
respiratory system development GO:0060541 213 0.022
organelle fission GO:0048285 340 0.021
immune response GO:0006955 246 0.021
response to organic substance GO:0010033 284 0.021
nitrogen compound transport GO:0071705 85 0.021
establishment of localization in cell GO:0051649 402 0.021
negative regulation of gene expression GO:0010629 387 0.021
protein complex assembly GO:0006461 200 0.021
sensory perception GO:0007600 196 0.020
kidney epithelium development GO:0072073 3 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
single organism catabolic process GO:0044712 228 0.020
camera type eye development GO:0043010 4 0.020
cell motility GO:0048870 251 0.020
taxis GO:0042330 304 0.020
cation transmembrane transport GO:0098655 88 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
embryonic morphogenesis GO:0048598 206 0.020
defense response to other organism GO:0098542 225 0.020
neuron recognition GO:0008038 101 0.020
regulation of transport GO:0051049 181 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
regulation of growth GO:0040008 233 0.020
connective tissue development GO:0061448 3 0.020
male gamete generation GO:0048232 201 0.020
multicellular organismal aging GO:0010259 140 0.020
lateral inhibition GO:0046331 206 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
regulation of immune response GO:0050776 118 0.019
spermatogenesis GO:0007283 200 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
epithelial cell development GO:0002064 274 0.019
phosphatidic acid metabolic process GO:0046473 1 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
macromolecular complex assembly GO:0065003 256 0.019
cellular response to oxygen containing compound GO:1901701 79 0.019
cell proliferation GO:0008283 299 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
actin filament based process GO:0030029 220 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.018
vitamin metabolic process GO:0006766 2 0.018
pigmentation GO:0043473 75 0.018
organophosphate metabolic process GO:0019637 195 0.018
single organism intracellular transport GO:1902582 207 0.018
wing disc morphogenesis GO:0007472 344 0.018
single organism behavior GO:0044708 391 0.018
response to nutrient levels GO:0031667 114 0.018
regulation of developmental growth GO:0048638 174 0.018
cell migration GO:0016477 238 0.018
organophosphate catabolic process GO:0046434 112 0.018
carbohydrate derivative metabolic process GO:1901135 217 0.018
negative regulation of cell communication GO:0010648 223 0.018
estrogen metabolic process GO:0008210 1 0.018
cellular protein localization GO:0034613 160 0.018
regulation of cellular protein metabolic process GO:0032268 243 0.017
regulation of programmed cell death GO:0043067 152 0.017
single organism cellular localization GO:1902580 180 0.017
phosphorylation GO:0016310 294 0.017
appendage development GO:0048736 401 0.017
forebrain development GO:0030900 2 0.017
nuclear division GO:0000280 332 0.017
regulation of cell cycle GO:0051726 291 0.017
cellular amine metabolic process GO:0044106 12 0.017
heterocycle catabolic process GO:0046700 166 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
response to endogenous stimulus GO:0009719 119 0.017
regulation of cell cycle process GO:0010564 181 0.017
ameboidal type cell migration GO:0001667 151 0.017
ribonucleoside catabolic process GO:0042454 112 0.017
positive regulation of signal transduction GO:0009967 223 0.017
intracellular transport GO:0046907 228 0.017
epithelium migration GO:0090132 148 0.017
endomembrane system organization GO:0010256 119 0.017
ovarian follicle cell development GO:0030707 248 0.017
regulation of anatomical structure size GO:0090066 163 0.017
eye development GO:0001654 323 0.017
appendage morphogenesis GO:0035107 397 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
negative regulation of signal transduction GO:0009968 206 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
response to starvation GO:0042594 97 0.016
response to decreased oxygen levels GO:0036293 58 0.016
pigment metabolic process GO:0042440 84 0.016
organic anion transport GO:0015711 28 0.016
regulation of multi organism process GO:0043900 131 0.016
ethanolamine containing compound metabolic process GO:0042439 4 0.016
response to organophosphorus GO:0046683 2 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
negative regulation of cellular metabolic process GO:0031324 382 0.016
apoptotic process GO:0006915 159 0.016
defense response to bacterium GO:0042742 178 0.016
negative regulation of signaling GO:0023057 219 0.016
positive regulation of cellular component organization GO:0051130 156 0.016
vesicle organization GO:0016050 44 0.016
chaeta development GO:0022416 97 0.016
response to organic cyclic compound GO:0014070 89 0.016
cell division GO:0051301 248 0.016
regulation of response to stress GO:0080134 200 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
organelle assembly GO:0070925 198 0.015
response to hypoxia GO:0001666 53 0.015
retina development in camera type eye GO:0060041 4 0.015
nucleotide metabolic process GO:0009117 161 0.015
regulation of cell substrate adhesion GO:0010810 2 0.015
tissue morphogenesis GO:0048729 297 0.015
nephron epithelium development GO:0072009 3 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
regulation of defense response GO:0031347 102 0.015
golgi organization GO:0007030 66 0.015
purine containing compound metabolic process GO:0072521 155 0.015
telencephalon development GO:0021537 2 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
acetylcholine metabolic process GO:0008291 2 0.015
detection of light stimulus GO:0009583 58 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
hormone catabolic process GO:0042447 3 0.015
regulation of catabolic process GO:0009894 170 0.015
negative regulation of cell death GO:0060548 81 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
cellular response to monosaccharide stimulus GO:0071326 2 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
g protein coupled receptor signaling pathway GO:0007186 136 0.014
xenobiotic catabolic process GO:0042178 1 0.014
transmembrane transport GO:0055085 139 0.014
nucleoside catabolic process GO:0009164 112 0.014
developmental maturation GO:0021700 172 0.014
regulation of molecular function GO:0065009 217 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
cellular response to organic substance GO:0071310 132 0.014
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.014
compound eye development GO:0048749 307 0.014
response to copper ion GO:0046688 4 0.014
regulation of cellular localization GO:0060341 136 0.014
negative regulation of biosynthetic process GO:0009890 277 0.014
gastrulation GO:0007369 70 0.014
actin cytoskeleton organization GO:0030036 206 0.014
tube morphogenesis GO:0035239 191 0.014
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
positive regulation of transport GO:0051050 92 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
secondary metabolic process GO:0019748 75 0.014
cellular response to molecule of bacterial origin GO:0071219 3 0.014
acetate ester metabolic process GO:1900619 2 0.014
regulation of organelle organization GO:0033043 196 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
regulation of cellular component biogenesis GO:0044087 201 0.014
spindle organization GO:0007051 253 0.014
response to oxidative stress GO:0006979 86 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
cellular response to carbohydrate stimulus GO:0071322 4 0.014
meiotic nuclear division GO:0007126 151 0.014
response to extracellular stimulus GO:0009991 116 0.014
nephron development GO:0072006 3 0.014
biological adhesion GO:0022610 138 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
cellular homeostasis GO:0019725 80 0.014
response to organonitrogen compound GO:0010243 75 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
ion homeostasis GO:0050801 55 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
nucleobase containing compound transport GO:0015931 56 0.014
cellular response to lipopolysaccharide GO:0071222 3 0.013
response to wounding GO:0009611 94 0.013
cation homeostasis GO:0055080 51 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
meiotic cell cycle GO:0051321 171 0.013
amine metabolic process GO:0009308 12 0.013
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
tube development GO:0035295 244 0.013
nucleoside metabolic process GO:0009116 127 0.013
digestive tract morphogenesis GO:0048546 127 0.013
cellular cation homeostasis GO:0030003 38 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
innate immune response GO:0045087 144 0.013
protein localization GO:0008104 284 0.013
negative regulation of developmental process GO:0051093 201 0.013
immune effector process GO:0002252 98 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
cellular component assembly involved in morphogenesis GO:0010927 151 0.013
cytoplasmic transport GO:0016482 130 0.013
anatomical structure homeostasis GO:0060249 97 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
skeletal muscle fiber development GO:0048741 3 0.013
cell recognition GO:0008037 102 0.013
regulation of protein metabolic process GO:0051246 256 0.013
axon development GO:0061564 297 0.013
inorganic cation transmembrane transport GO:0098662 61 0.013
cholesterol homeostasis GO:0042632 3 0.013
gland development GO:0048732 191 0.013
ribonucleotide catabolic process GO:0009261 109 0.013
determination of adult lifespan GO:0008340 137 0.013
female meiotic division GO:0007143 70 0.013
immune response activating signal transduction GO:0002757 2 0.013
imaginal disc derived appendage morphogenesis GO:0035114 395 0.013
positive regulation of growth GO:0045927 75 0.013
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
protein transport GO:0015031 155 0.013
negative regulation of rna metabolic process GO:0051253 251 0.013
autophagy GO:0006914 108 0.013
inorganic ion transmembrane transport GO:0098660 73 0.013
single organism carbohydrate metabolic process GO:0044723 72 0.013
imaginal disc pattern formation GO:0007447 91 0.013
notch signaling pathway GO:0007219 120 0.013
mitochondrion organization GO:0007005 65 0.012
positive regulation of gene expression GO:0010628 290 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
cuticle development GO:0042335 86 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
mitotic nuclear division GO:0007067 213 0.012
gastrulation with mouth forming first GO:0001703 36 0.012
developmental programmed cell death GO:0010623 138 0.012
cilium assembly GO:0042384 38 0.012
secretion by cell GO:0032940 101 0.012
positive regulation of lipid storage GO:0010884 4 0.012
protein phosphorylation GO:0006468 169 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
chromosome segregation GO:0007059 157 0.012
axonogenesis GO:0007409 290 0.012
gastrulation involving germ band extension GO:0010004 36 0.012
tissue migration GO:0090130 155 0.012
compound eye morphogenesis GO:0001745 249 0.012
response to mercury ion GO:0046689 3 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
cell adhesion GO:0007155 136 0.012
macromolecule catabolic process GO:0009057 161 0.012
establishment of protein localization GO:0045184 163 0.012
regulation of cell development GO:0060284 215 0.012
nephron tubule development GO:0072080 3 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
cellular macromolecule catabolic process GO:0044265 136 0.012
monocarboxylic acid transport GO:0015718 3 0.012
sensory organ morphogenesis GO:0090596 260 0.012
lipid metabolic process GO:0006629 121 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
mitotic spindle organization GO:0007052 220 0.012
protein hydroxylation GO:0018126 1 0.012
salivary gland morphogenesis GO:0007435 145 0.012
regulation of cell differentiation GO:0045595 302 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
choline metabolic process GO:0019695 1 0.012
purine ribonucleotide catabolic process GO:0009154 109 0.012
digestive tract development GO:0048565 149 0.012
neutral lipid catabolic process GO:0046461 3 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
steroid catabolic process GO:0006706 1 0.011
peptide metabolic process GO:0006518 80 0.011
benzene containing compound metabolic process GO:0042537 3 0.011
wnt signaling pathway GO:0016055 98 0.011
regulation of cellular catabolic process GO:0031329 157 0.011
eye pigment biosynthetic process GO:0006726 32 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
mesenchymal cell differentiation GO:0048762 1 0.011
purine containing compound catabolic process GO:0072523 112 0.011
response to alcohol GO:0097305 95 0.011
cell projection assembly GO:0030031 94 0.011
segmentation GO:0035282 207 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
aging GO:0007568 143 0.011
organelle fusion GO:0048284 46 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
cellular protein complex assembly GO:0043623 71 0.011
pyridine containing compound metabolic process GO:0072524 3 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
cellular response to ethanol GO:0071361 4 0.011
fat soluble vitamin metabolic process GO:0006775 1 0.011
eye pigmentation GO:0048069 43 0.011
pigment biosynthetic process GO:0046148 36 0.011
positive regulation of catabolic process GO:0009896 105 0.011
cellular macromolecule localization GO:0070727 220 0.011
muscle structure development GO:0061061 224 0.011
regulation of apoptotic process GO:0042981 130 0.011
chemotaxis GO:0006935 249 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
positive regulation of immune response GO:0050778 63 0.011
purine nucleoside catabolic process GO:0006152 112 0.011
regulation of catalytic activity GO:0050790 185 0.011
wing disc pattern formation GO:0035222 66 0.011
muscle organ development GO:0007517 127 0.011
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.011
cell cell junction organization GO:0045216 55 0.011
actin filament organization GO:0007015 126 0.011
gland morphogenesis GO:0022612 145 0.011
phototransduction GO:0007602 52 0.011
eye morphogenesis GO:0048592 260 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
negative regulation of cell cycle GO:0045786 116 0.011
response to nitrogen compound GO:1901698 90 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
leg disc development GO:0035218 92 0.011
wound healing GO:0042060 75 0.011
sensory perception of smell GO:0007608 80 0.011
proteolysis GO:0006508 192 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
membrane organization GO:0061024 112 0.010
exocytosis GO:0006887 28 0.010
regulation of vesicle mediated transport GO:0060627 59 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
sensory perception of pain GO:0019233 4 0.010
carbohydrate derivative biosynthetic process GO:1901137 85 0.010
protein localization to organelle GO:0033365 82 0.010
somatic muscle development GO:0007525 66 0.010
spermatid differentiation GO:0048515 114 0.010
positive regulation of developmental process GO:0051094 143 0.010
cellular ketone metabolic process GO:0042180 24 0.010
pigment metabolic process involved in pigmentation GO:0043474 33 0.010
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.010
regulation of cell proliferation GO:0042127 163 0.010
very long chain fatty acid metabolic process GO:0000038 4 0.010
ovarian follicle cell migration GO:0007297 121 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
nucleotide catabolic process GO:0009166 109 0.010
mesenchymal cell development GO:0014031 1 0.010
anion homeostasis GO:0055081 3 0.010
molting cycle chitin based cuticle GO:0007591 56 0.010

Prestin disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
disease of metabolism DOID:0014667 0 0.027
nervous system disease DOID:863 0 0.023
urinary system disease DOID:18 0 0.021
renal tubular transport disease DOID:447 0 0.018
kidney disease DOID:557 0 0.018
cardiovascular system disease DOID:1287 0 0.015
inherited metabolic disorder DOID:655 0 0.015
musculoskeletal system disease DOID:17 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
artery disease DOID:0050828 0 0.011
vascular disease DOID:178 0 0.011
diabetes mellitus DOID:9351 0 0.010
type 2 diabetes mellitus DOID:9352 0 0.010
carbohydrate metabolism disease DOID:0050013 0 0.010
glucose metabolism disease DOID:4194 0 0.010
acquired metabolic disease DOID:0060158 0 0.010
central nervous system disease DOID:331 0 0.010