Drosophila melanogaster

0 known processes

TwdlK (Dmel_CG6460)

TweedleK

(Aliases: Dmel\CG6460,CG6460)

TwdlK biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to organic substance GO:0010033 284 0.045
defense response GO:0006952 300 0.044
organonitrogen compound metabolic process GO:1901564 318 0.041
body morphogenesis GO:0010171 2 0.041
Fly
imaginal disc derived appendage development GO:0048737 399 0.038
neurological system process GO:0050877 358 0.038
sensory perception of chemical stimulus GO:0007606 116 0.035
sterol homeostasis GO:0055092 4 0.035
response to abiotic stimulus GO:0009628 341 0.034
salt aversion GO:0035199 3 0.034
oxoacid metabolic process GO:0043436 103 0.034
immune system process GO:0002376 347 0.033
innate immune response GO:0045087 144 0.032
lateral inhibition GO:0046331 206 0.031
vesicle mediated transport GO:0016192 381 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.031
cellular response to chemical stimulus GO:0070887 199 0.031
small molecule metabolic process GO:0044281 305 0.031
endocytosis GO:0006897 310 0.030
response to other organism GO:0051707 293 0.029
appendage development GO:0048736 401 0.029
organic substance catabolic process GO:1901575 308 0.029
phagocytosis GO:0006909 215 0.029
carboxylic acid metabolic process GO:0019752 92 0.029
positive regulation of response to stimulus GO:0048584 323 0.029
humoral immune response GO:0006959 117 0.028
detection of abiotic stimulus GO:0009582 66 0.028
catabolic process GO:0009056 409 0.028
appendage morphogenesis GO:0035107 397 0.027
organic acid metabolic process GO:0006082 103 0.027
immune response GO:0006955 246 0.027
post embryonic appendage morphogenesis GO:0035120 385 0.027
cholesterol homeostasis GO:0042632 3 0.027
cell cell signaling involved in cell fate commitment GO:0045168 210 0.027
response to bacterium GO:0009617 198 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
forebrain development GO:0030900 2 0.026
response to oxygen containing compound GO:1901700 200 0.026
response to biotic stimulus GO:0009607 294 0.026
regionalization GO:0003002 416 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
compound eye development GO:0048749 307 0.025
anion homeostasis GO:0055081 3 0.025
taxis GO:0042330 304 0.025
regulation of localization GO:0032879 275 0.025
single organism behavior GO:0044708 391 0.024
positive regulation of biosynthetic process GO:0009891 316 0.024
regulation of multicellular organismal development GO:2000026 414 0.023
positive regulation of macromolecule metabolic process GO:0010604 405 0.023
telencephalon development GO:0021537 2 0.023
cellular catabolic process GO:0044248 372 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
single organism biosynthetic process GO:0044711 206 0.022
xenobiotic catabolic process GO:0042178 1 0.022
sensory organ morphogenesis GO:0090596 260 0.022
lipid metabolic process GO:0006629 121 0.022
organophosphate metabolic process GO:0019637 195 0.022
sensory perception GO:0007600 196 0.022
positive regulation of signaling GO:0023056 243 0.021
organonitrogen compound biosynthetic process GO:1901566 117 0.021
protein complex biogenesis GO:0070271 201 0.021
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
camera type eye development GO:0043010 4 0.021
wing disc morphogenesis GO:0007472 344 0.021
cuticle development GO:0042335 86 0.021
Fly
cellular amino acid metabolic process GO:0006520 61 0.021
salivary gland development GO:0007431 162 0.021
cell proliferation GO:0008283 299 0.021
negative regulation of cellular metabolic process GO:0031324 382 0.020
cellular response to organic substance GO:0071310 132 0.020
organic substance transport GO:0071702 257 0.020
cellular protein modification process GO:0006464 438 0.020
response to lipopolysaccharide GO:0032496 4 0.020
chitin based cuticle development GO:0040003 49 0.020
Fly
response to external biotic stimulus GO:0043207 293 0.020
cell death GO:0008219 279 0.020
positive regulation of gene expression GO:0010628 290 0.020
response to wounding GO:0009611 94 0.020
eye development GO:0001654 323 0.020
triglyceride catabolic process GO:0019433 3 0.020
transcription from rna polymerase ii promoter GO:0006366 368 0.020
regulation of cell differentiation GO:0045595 302 0.019
cellular lipid metabolic process GO:0044255 83 0.019
compound eye morphogenesis GO:0001745 249 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
positive regulation of cell communication GO:0010647 250 0.019
developmental growth GO:0048589 280 0.019
positive regulation of cellular biosynthetic process GO:0031328 316 0.019
negative regulation of response to stimulus GO:0048585 258 0.019
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.019
programmed cell death GO:0012501 257 0.019
connective tissue development GO:0061448 3 0.019
death GO:0016265 284 0.019
response to temperature stimulus GO:0009266 106 0.019
response to nitrogen compound GO:1901698 90 0.019
growth GO:0040007 359 0.019
wound healing GO:0042060 75 0.019
negative regulation of nucleic acid templated transcription GO:1903507 240 0.019
macromolecular complex assembly GO:0065003 256 0.019
organelle fission GO:0048285 340 0.019
protein modification process GO:0036211 438 0.019
positive regulation of transcription dna templated GO:0045893 266 0.019
gland development GO:0048732 191 0.019
exocrine system development GO:0035272 162 0.018
regulation of transport GO:0051049 181 0.018
regulation of cellular ketone metabolic process GO:0010565 3 0.018
eye morphogenesis GO:0048592 260 0.018
axis specification GO:0009798 167 0.018
phospholipid homeostasis GO:0055091 1 0.018
positive regulation of signal transduction GO:0009967 223 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
peptidyl proline hydroxylation GO:0019511 1 0.018
sensory perception of salty taste GO:0050914 3 0.018
single organism catabolic process GO:0044712 228 0.018
regulation of cell cycle GO:0051726 291 0.018
salivary gland morphogenesis GO:0007435 145 0.017
single organism cellular localization GO:1902580 180 0.017
phosphorylation GO:0016310 294 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
intracellular signal transduction GO:0035556 300 0.017
homeostatic process GO:0042592 199 0.017
aromatic compound catabolic process GO:0019439 166 0.017
neutral lipid biosynthetic process GO:0046460 2 0.017
epiboly involved in wound healing GO:0090505 2 0.017
regulation of sequestering of triglyceride GO:0010889 3 0.017
response to endogenous stimulus GO:0009719 119 0.016
heterocycle catabolic process GO:0046700 166 0.016
protein localization GO:0008104 284 0.016
protein complex assembly GO:0006461 200 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
dorsal ventral pattern formation GO:0009953 133 0.016
positive regulation of rna metabolic process GO:0051254 271 0.016
triglyceride biosynthetic process GO:0019432 2 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
ion transport GO:0006811 145 0.016
negative regulation of gene expression GO:0010629 387 0.016
localization of cell GO:0051674 257 0.016
hormone catabolic process GO:0042447 3 0.016
apoptotic process GO:0006915 159 0.016
defense response to bacterium GO:0042742 178 0.016
gland morphogenesis GO:0022612 145 0.016
response to copper ion GO:0046688 4 0.016
cellular amine metabolic process GO:0044106 12 0.016
cellular response to ethanol GO:0071361 4 0.016
regulation of programmed cell death GO:0043067 152 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
sensory perception of smell GO:0007608 80 0.016
regulation of multi organism process GO:0043900 131 0.016
small gtpase mediated signal transduction GO:0007264 88 0.016
kidney development GO:0001822 3 0.016
regulation of notch signaling pathway GO:0008593 100 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
notch signaling pathway GO:0007219 120 0.015
cell motility GO:0048870 251 0.015
regulation of anatomical structure morphogenesis GO:0022603 242 0.015
detection of external stimulus GO:0009581 66 0.015
glycerolipid catabolic process GO:0046503 3 0.015
cell division GO:0051301 248 0.015
compound eye photoreceptor cell differentiation GO:0001751 140 0.015
regulation of cellular amine metabolic process GO:0033238 3 0.015
negative regulation of multicellular organismal process GO:0051241 142 0.015
morphogenesis of an epithelium GO:0002009 276 0.015
regulation of response to external stimulus GO:0032101 115 0.015
secondary metabolic process GO:0019748 75 0.015
nucleoside metabolic process GO:0009116 127 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
regulation of apoptotic process GO:0042981 130 0.015
hindbrain development GO:0030902 2 0.015
negative regulation of cellular biosynthetic process GO:0031327 277 0.015
steroid catabolic process GO:0006706 1 0.015
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.015
detection of stimulus GO:0051606 156 0.014
positive regulation of cell motility GO:2000147 3 0.014
cellular macromolecule localization GO:0070727 220 0.014
response to nutrient levels GO:0031667 114 0.014
drinking behavior GO:0042756 2 0.014
chemical homeostasis GO:0048878 92 0.014
nuclear division GO:0000280 332 0.014
segmentation GO:0035282 207 0.014
blastoderm segmentation GO:0007350 159 0.014
nucleobase containing small molecule metabolic process GO:0055086 174 0.014
cholesterol transport GO:0030301 2 0.014
establishment of localization in cell GO:0051649 402 0.014
response to organonitrogen compound GO:0010243 75 0.014
cytoplasmic transport GO:0016482 130 0.014
ras protein signal transduction GO:0007265 88 0.014
actin filament based process GO:0030029 220 0.014
negative regulation of rna biosynthetic process GO:1902679 240 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
proteolysis GO:0006508 192 0.014
cation transport GO:0006812 110 0.014
eye photoreceptor cell differentiation GO:0001754 145 0.014
protein hydroxylation GO:0018126 1 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
feeding behavior GO:0007631 50 0.014
cellular ketone metabolic process GO:0042180 24 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
tissue morphogenesis GO:0048729 297 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
chemotaxis GO:0006935 249 0.014
amine metabolic process GO:0009308 12 0.014
intracellular transport GO:0046907 228 0.014
purine containing compound metabolic process GO:0072521 155 0.014
androgen metabolic process GO:0008209 1 0.014
regulation of reproductive process GO:2000241 54 0.014
negative regulation of biosynthetic process GO:0009890 277 0.013
organelle assembly GO:0070925 198 0.013
mitotic nuclear division GO:0007067 213 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
adult behavior GO:0030534 137 0.013
response to alcohol GO:0097305 95 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
neutral lipid catabolic process GO:0046461 3 0.013
ethanolamine containing compound metabolic process GO:0042439 4 0.013
cation transmembrane transport GO:0098655 88 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
neuron projection guidance GO:0097485 241 0.013
epithelial cell development GO:0002064 274 0.013
cellular response to endogenous stimulus GO:0071495 80 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
embryonic pattern specification GO:0009880 174 0.013
positive regulation of sequestering of triglyceride GO:0010890 1 0.013
cellular response to water stimulus GO:0071462 2 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
cell maturation GO:0048469 144 0.013
camera type eye morphogenesis GO:0048593 2 0.013
developmental maturation GO:0021700 172 0.013
peptide metabolic process GO:0006518 80 0.013
limb development GO:0060173 1 0.013
regulation of anatomical structure size GO:0090066 163 0.013
macromolecule catabolic process GO:0009057 161 0.013
regulation of cell death GO:0010941 173 0.013
endomembrane system organization GO:0010256 119 0.013
phosphatidic acid metabolic process GO:0046473 1 0.013
regulation of lipid transport GO:0032368 3 0.013
dorsal ventral axis specification GO:0009950 66 0.013
single organism intracellular transport GO:1902582 207 0.013
regulation of response to stress GO:0080134 200 0.013
organophosphate catabolic process GO:0046434 112 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
regulation of synapse assembly GO:0051963 94 0.013
purine containing compound catabolic process GO:0072523 112 0.012
metal ion transport GO:0030001 74 0.012
immune effector process GO:0002252 98 0.012
positive regulation of lipid storage GO:0010884 4 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
respiratory system development GO:0060541 213 0.012
alditol phosphate metabolic process GO:0052646 2 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
positive regulation of phosphorus metabolic process GO:0010562 139 0.012
negative regulation of transcription dna templated GO:0045892 237 0.012
defense response to other organism GO:0098542 225 0.012
regulation of developmental growth GO:0048638 174 0.012
antimicrobial humoral response GO:0019730 99 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
regulation of cell development GO:0060284 215 0.012
regulation of production of molecular mediator of immune response GO:0002700 44 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
regulation of nervous system development GO:0051960 248 0.012
protein transport GO:0015031 155 0.012
acylglycerol biosynthetic process GO:0046463 2 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
ribonucleotide metabolic process GO:0009259 145 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
negative regulation of developmental process GO:0051093 201 0.012
regulation of behavior GO:0050795 75 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
cellular response to oxygen containing compound GO:1901701 79 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
digestive tract development GO:0048565 149 0.012
cellular protein localization GO:0034613 160 0.012
cell migration GO:0016477 238 0.012
response to organic cyclic compound GO:0014070 89 0.012
water homeostasis GO:0030104 3 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
sensory perception of pain GO:0019233 4 0.012
regulation of intracellular signal transduction GO:1902531 236 0.012
mesenchymal cell development GO:0014031 1 0.012
axon guidance GO:0007411 233 0.011
establishment of protein localization GO:0045184 163 0.011
positive regulation of cell migration GO:0030335 2 0.011
axon development GO:0061564 297 0.011
anterior posterior axis specification embryo GO:0008595 103 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
melanin metabolic process GO:0006582 47 0.011
retina development in camera type eye GO:0060041 4 0.011
l amino acid import GO:0043092 2 0.011
cellular response to nitrogen compound GO:1901699 51 0.011
response to decreased oxygen levels GO:0036293 58 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
digestive tract morphogenesis GO:0048546 127 0.011
digestive system development GO:0055123 149 0.011
central nervous system development GO:0007417 201 0.011
spindle organization GO:0007051 253 0.011
tube development GO:0035295 244 0.011
epithelial cell differentiation GO:0030855 322 0.011
transmembrane transport GO:0055085 139 0.011
axonogenesis GO:0007409 290 0.011
phosphate ion transport GO:0006817 4 0.011
developmental programmed cell death GO:0010623 138 0.011
multi multicellular organism process GO:0044706 123 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
multi organism behavior GO:0051705 175 0.011
monocarboxylic acid transport GO:0015718 3 0.011
hematopoietic progenitor cell differentiation GO:0002244 1 0.011
actin cytoskeleton organization GO:0030036 206 0.011
organonitrogen compound catabolic process GO:1901565 128 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.011
melanization defense response GO:0035006 45 0.011
nucleotide metabolic process GO:0009117 161 0.011
regulation of organelle organization GO:0033043 196 0.011
negative regulation of cell differentiation GO:0045596 143 0.011
regulation of growth GO:0040008 233 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
autophagic cell death GO:0048102 83 0.011
cellular response to carbohydrate stimulus GO:0071322 4 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
gene silencing GO:0016458 138 0.011
spinal cord development GO:0021510 1 0.011
synaptic transmission GO:0007268 288 0.011
histolysis GO:0007559 102 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
embryonic axis specification GO:0000578 107 0.011
regulation of cell cycle process GO:0010564 181 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
l glutamate import GO:0051938 1 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
behavioral response to pain GO:0048266 3 0.011
phosphatidylcholine metabolic process GO:0046470 3 0.011
immune response activating signal transduction GO:0002757 2 0.011
negative regulation of cell cycle GO:0045786 116 0.011
stem cell differentiation GO:0048863 117 0.011
response to organophosphorus GO:0046683 2 0.010
regulation of immune system process GO:0002682 176 0.010
positive regulation of melanization defense response GO:0035008 1 0.010
protein maturation GO:0051604 71 0.010
courtship behavior GO:0007619 68 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
sodium dependent phosphate transport GO:0044341 2 0.010
anterior posterior axis specification GO:0009948 109 0.010
leg disc development GO:0035218 92 0.010
response to hypoxia GO:0001666 53 0.010
protein phosphorylation GO:0006468 169 0.010
locomotory behavior GO:0007626 176 0.010
g protein coupled receptor signaling pathway coupled to cyclic nucleotide second messenger GO:0007187 17 0.010
photoreceptor cell development GO:0042461 96 0.010
salivary gland cell autophagic cell death GO:0035071 83 0.010
tripartite regional subdivision GO:0007351 103 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
ribonucleoside triphosphate metabolic process GO:0009199 119 0.010
regulation of response to biotic stimulus GO:0002831 63 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
monocarboxylic acid metabolic process GO:0032787 29 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
regulation of protein metabolic process GO:0051246 256 0.010
anterior posterior pattern specification GO:0009952 136 0.010
protein heterooligomerization GO:0051291 4 0.010
chaeta development GO:0022416 97 0.010

TwdlK disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.045
renal tubular transport disease DOID:447 0 0.027
kidney disease DOID:557 0 0.027
urinary system disease DOID:18 0 0.027
disease of metabolism DOID:0014667 0 0.021
nervous system disease DOID:863 0 0.017
inherited metabolic disorder DOID:655 0 0.017
familial hypertriglyceridemia DOID:0050527 0 0.015
lipid metabolism disorder DOID:3146 0 0.015
diabetes mellitus DOID:9351 0 0.015
type 2 diabetes mellitus DOID:9352 0 0.015
carbohydrate metabolism disease DOID:0050013 0 0.015
glucose metabolism disease DOID:4194 0 0.015
acquired metabolic disease DOID:0060158 0 0.015
respiratory system disease DOID:1579 0 0.013
lower respiratory tract disease DOID:0050161 0 0.013
bronchial disease DOID:1176 0 0.013
bronchiectasis DOID:9563 0 0.013
cardiovascular system disease DOID:1287 0 0.013
liddle syndrome DOID:0050477 0 0.012
hair disease DOID:421 0 0.011
integumentary system disease DOID:16 0 0.011
hypotrichosis DOID:4535 0 0.011
familial lipoprotein lipase deficiency DOID:14118 0 0.011
familial hyperlipidemia DOID:1168 0 0.011
musculoskeletal system disease DOID:17 0 0.010
familial combined hyperlipidemia DOID:13809 0 0.010