Drosophila melanogaster

85 known processes

nct (Dmel_CG7012)

nicastrin

(Aliases: ST96B,S5A,Nic,Nct,agro,nic,CG7012,dNct,Dmel\CG7012)

nct biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
wing disc morphogenesis GO:0007472 344 0.908
axon guidance GO:0007411 233 0.872
appendage development GO:0048736 401 0.866
cell growth GO:0016049 108 0.793
regionalization GO:0003002 416 0.748
imaginal disc derived appendage development GO:0048737 399 0.730
negative regulation of cell communication GO:0010648 223 0.726
immune system process GO:0002376 347 0.711
Mouse
growth GO:0040007 359 0.700
imaginal disc derived wing morphogenesis GO:0007476 337 0.691
post embryonic appendage morphogenesis GO:0035120 385 0.655
negative regulation of cell proliferation GO:0008285 69 0.647
regulation of nervous system development GO:0051960 248 0.631
axonogenesis GO:0007409 290 0.628
retinal ganglion cell axon guidance GO:0031290 12 0.625
establishment of localization in cell GO:0051649 402 0.589
neuron projection guidance GO:0097485 241 0.523
protein localization GO:0008104 284 0.516
appendage morphogenesis GO:0035107 397 0.508
tissue morphogenesis GO:0048729 297 0.461
regulation of wnt signaling pathway GO:0030111 68 0.433
eye morphogenesis GO:0048592 260 0.432
imaginal disc derived appendage morphogenesis GO:0035114 395 0.427
intracellular distribution of mitochondria GO:0048312 5 0.417
negative regulation of response to stimulus GO:0048585 258 0.413
organic substance catabolic process GO:1901575 308 0.395
regulation of developmental growth GO:0048638 174 0.376
imaginal disc derived wing vein specification GO:0007474 48 0.364
notch signaling pathway GO:0007219 120 0.360
negative regulation of signal transduction GO:0009968 206 0.352
embryonic morphogenesis GO:0048598 206 0.348
Worm
single organism intracellular transport GO:1902582 207 0.344
intracellular signal transduction GO:0035556 300 0.327
homeostatic process GO:0042592 199 0.322
Mouse
organic substance transport GO:0071702 257 0.317
regulation of cell death GO:0010941 173 0.302
negative regulation of notch signaling pathway GO:0045746 41 0.300
regulation of notch signaling pathway GO:0008593 100 0.297
neuronal stem cell division GO:0036445 35 0.293
tube development GO:0035295 244 0.291
Worm
compound eye development GO:0048749 307 0.284
regulation of transport GO:0051049 181 0.283
lipid metabolic process GO:0006629 121 0.250
regulation of localization GO:0032879 275 0.248
heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process GO:0015014 5 0.244
wnt signaling pathway GO:0016055 98 0.242
regulation of cell differentiation GO:0045595 302 0.227
asymmetric neuroblast division GO:0055059 33 0.219
regulation of growth GO:0040008 233 0.216
positive regulation of cell communication GO:0010647 250 0.215
positive regulation of wnt signaling pathway GO:0030177 25 0.212
axon development GO:0061564 297 0.211
brain development GO:0007420 120 0.199
dorsal appendage formation GO:0046843 47 0.198
chemotaxis GO:0006935 249 0.198
positive regulation of hh target transcription factor activity GO:0007228 5 0.197
regulation of neurogenesis GO:0050767 158 0.194
regulation of cellular component size GO:0032535 98 0.186
apoptotic process GO:0006915 159 0.185
cellular lipid metabolic process GO:0044255 83 0.181
stem cell fate determination GO:0048867 15 0.179
positive regulation of jun kinase activity GO:0043507 4 0.177
cell recognition GO:0008037 102 0.175
protein catabolic process GO:0030163 101 0.175
regulation of cell growth GO:0001558 43 0.174
tube morphogenesis GO:0035239 191 0.170
organ growth GO:0035265 56 0.167
response to oxygen containing compound GO:1901700 200 0.167
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.163
programmed cell death GO:0012501 257 0.163
negative regulation of gene expression GO:0010629 387 0.160
reproductive behavior GO:0019098 122 0.160
Worm
neuron projection extension GO:1990138 32 0.153
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.152
regulation of filopodium assembly GO:0051489 24 0.152
developmental growth involved in morphogenesis GO:0060560 65 0.151
regulation of protein transport GO:0051223 57 0.150
developmental growth GO:0048589 280 0.150
sensory organ morphogenesis GO:0090596 260 0.148
proteasomal protein catabolic process GO:0010498 59 0.145
intracellular protein transport GO:0006886 104 0.144
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 1 0.142
eye photoreceptor cell differentiation GO:0001754 145 0.140
imaginal disc pattern formation GO:0007447 91 0.137
forebrain development GO:0030900 2 0.135
epithelial cell differentiation GO:0030855 322 0.135
regulation of canonical wnt signaling pathway GO:0060828 15 0.132
single organism catabolic process GO:0044712 228 0.129
g protein coupled receptor signaling pathway GO:0007186 136 0.127
negative regulation of intracellular signal transduction GO:1902532 57 0.126
death GO:0016265 284 0.125
regulation of epithelial cell proliferation GO:0050678 4 0.122
oocyte fate determination GO:0030716 27 0.120
positive regulation of molecular function GO:0044093 136 0.119
protein modification process GO:0036211 438 0.118
notch receptor processing GO:0007220 13 0.118
periodic partitioning GO:0007365 29 0.118
digestive system development GO:0055123 149 0.115
Worm
actin filament based process GO:0030029 220 0.115
positive regulation of protein modification process GO:0031401 58 0.114
regulation of protein localization GO:0032880 76 0.114
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.111
organelle localization GO:0051640 148 0.111
photoreceptor cell differentiation GO:0046530 170 0.111
positive regulation of canonical wnt signaling pathway GO:0090263 7 0.110
nuclear division GO:0000280 332 0.108
protein transport GO:0015031 155 0.107
neuron recognition GO:0008038 101 0.106
protein ubiquitination GO:0016567 70 0.105
cell death GO:0008219 279 0.105
taxis GO:0042330 304 0.102
regulation of response to stress GO:0080134 200 0.101
cytoplasmic transport GO:0016482 130 0.100
organic acid metabolic process GO:0006082 103 0.099
multicellular organismal homeostasis GO:0048871 41 0.099
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.094
phosphorylation GO:0016310 294 0.092
regulation of system process GO:0044057 36 0.088
developmental cell growth GO:0048588 52 0.088
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.087
regulation of cell size GO:0008361 63 0.085
response to organic substance GO:0010033 284 0.085
regulation of molecular function GO:0065009 217 0.085
asymmetric cell division GO:0008356 37 0.085
cellular macromolecule localization GO:0070727 220 0.084
catabolic process GO:0009056 409 0.084
wound healing GO:0042060 75 0.084
morphogenesis of an epithelium GO:0002009 276 0.084
sensory perception of mechanical stimulus GO:0050954 72 0.084
chondroitin sulfate proteoglycan biosynthetic process GO:0050650 3 0.083
negative regulation of rna metabolic process GO:0051253 251 0.082
regulation of stem cell proliferation GO:0072091 40 0.082
organonitrogen compound metabolic process GO:1901564 318 0.081
Mouse
regulation of cytoskeleton organization GO:0051493 89 0.081
muscle structure development GO:0061061 224 0.081
chemical homeostasis GO:0048878 92 0.080
learning or memory GO:0007611 141 0.078
heart development GO:0007507 82 0.077
digestive tract morphogenesis GO:0048546 127 0.077
regulation of cell proliferation GO:0042127 163 0.077
actin filament organization GO:0007015 126 0.076
negative regulation of cellular metabolic process GO:0031324 382 0.076
camera type eye morphogenesis GO:0048593 2 0.076
stem cell fate commitment GO:0048865 25 0.075
negative regulation of nervous system development GO:0051961 92 0.075
cell motility GO:0048870 251 0.074
cell migration GO:0016477 238 0.074
intracellular transport GO:0046907 228 0.073
histolysis GO:0007559 102 0.072
regulation of intracellular protein transport GO:0033157 46 0.072
motor neuron axon guidance GO:0008045 58 0.072
regulation of response to gamma radiation GO:2001228 4 0.071
positive regulation of signaling GO:0023056 243 0.069
oxoacid metabolic process GO:0043436 103 0.069
single organismal cell cell adhesion GO:0016337 45 0.068
stem cell differentiation GO:0048863 117 0.068
negative regulation of signaling GO:0023057 219 0.068
cilium morphogenesis GO:0060271 39 0.067
eye development GO:0001654 323 0.067
stem cell proliferation GO:0072089 88 0.067
synaptic transmission GO:0007268 288 0.066
head development GO:0060322 135 0.066
regulation of actin cytoskeleton organization GO:0032956 42 0.065
germ line cyst formation GO:0048134 44 0.065
hindbrain development GO:0030902 2 0.065
heparin metabolic process GO:0030202 4 0.064
endocytosis GO:0006897 310 0.063
positive regulation of catalytic activity GO:0043085 118 0.063
regulation of hippo signaling GO:0035330 14 0.063
positive regulation of signal transduction GO:0009967 223 0.063
regulation of catalytic activity GO:0050790 185 0.062
peripheral nervous system development GO:0007422 52 0.062
negative regulation of nucleic acid templated transcription GO:1903507 240 0.062
eggshell formation GO:0030703 105 0.062
spindle organization GO:0007051 253 0.061
response to wounding GO:0009611 94 0.061
axon extension GO:0048675 32 0.061
positive regulation of cell differentiation GO:0045597 64 0.060
columnar cuboidal epithelial cell development GO:0002066 249 0.060
circulatory system development GO:0072359 82 0.060
germ cell migration GO:0008354 43 0.059
regulation of anatomical structure size GO:0090066 163 0.059
muscle cell differentiation GO:0042692 103 0.058
purine containing compound metabolic process GO:0072521 155 0.058
neurological system process GO:0050877 358 0.057
negative regulation of actin filament depolymerization GO:0030835 2 0.057
negative regulation of developmental growth GO:0048640 64 0.057
imaginal disc derived wing hair organization GO:0035317 45 0.055
asymmetric stem cell division GO:0098722 49 0.055
regulation of mitosis GO:0007088 56 0.055
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.054
chaeta morphogenesis GO:0008407 42 0.054
multi multicellular organism process GO:0044706 123 0.053
Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.053
macromolecule catabolic process GO:0009057 161 0.051
central nervous system development GO:0007417 201 0.051
germarium derived oocyte fate determination GO:0007294 26 0.051
regulation of execution phase of apoptosis GO:1900117 5 0.050
canonical wnt signaling pathway GO:0060070 21 0.050
protein modification by small protein conjugation or removal GO:0070647 106 0.050
positive regulation of cellular biosynthetic process GO:0031328 316 0.050
behavioral response to ethanol GO:0048149 49 0.050
cellular response to organic substance GO:0071310 132 0.050
organelle assembly GO:0070925 198 0.050
retina morphogenesis in camera type eye GO:0060042 2 0.050
neuroblast fate determination GO:0007400 12 0.050
positive regulation of transferase activity GO:0051347 26 0.049
gastrulation GO:0007369 70 0.049
regulation of axonogenesis GO:0050770 32 0.049
neural precursor cell proliferation GO:0061351 75 0.049
small molecule metabolic process GO:0044281 305 0.048
regulation of cell development GO:0060284 215 0.048
single organism behavior GO:0044708 391 0.048
synapse assembly GO:0007416 143 0.048
protein phosphorylation GO:0006468 169 0.048
synaptic target recognition GO:0008039 45 0.048
embryonic pattern specification GO:0009880 174 0.048
hippo signaling GO:0035329 20 0.047
production of small rna involved in gene silencing by rna GO:0070918 15 0.047
purine ribonucleotide catabolic process GO:0009154 109 0.047
phagocytosis GO:0006909 215 0.047
organophosphate metabolic process GO:0019637 195 0.047
metal ion homeostasis GO:0055065 44 0.046
single organism biosynthetic process GO:0044711 206 0.046
negative regulation of insulin receptor signaling pathway GO:0046627 11 0.046
limb development GO:0060173 1 0.046
negative regulation of cellular component organization GO:0051129 108 0.046
localization of cell GO:0051674 257 0.046
nf kappab import into nucleus GO:0042348 1 0.046
regulation of intracellular signal transduction GO:1902531 236 0.045
regulation of map kinase activity GO:0043405 17 0.045
retina development in camera type eye GO:0060041 4 0.045
signal transduction by phosphorylation GO:0023014 107 0.044
regulation of neuron projection development GO:0010975 69 0.044
regulation of cytoplasmic transport GO:1903649 47 0.044
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.044
dendrite guidance GO:0070983 21 0.044
nucleoside phosphate catabolic process GO:1901292 110 0.044
carbohydrate derivative metabolic process GO:1901135 217 0.044
negative regulation of rna biosynthetic process GO:1902679 240 0.044
response to endogenous stimulus GO:0009719 119 0.043
negative regulation of multicellular organismal process GO:0051241 142 0.043
defense response to other organism GO:0098542 225 0.043
regulation of cellular catabolic process GO:0031329 157 0.043
ras protein signal transduction GO:0007265 88 0.043
regulation of cell projection organization GO:0031344 92 0.042
positive regulation of transport GO:0051050 92 0.042
establishment of protein localization GO:0045184 163 0.042
gland development GO:0048732 191 0.041
epithelial cell development GO:0002064 274 0.041
single organism cellular localization GO:1902580 180 0.041
chorion containing eggshell formation GO:0007304 105 0.040
regulation of nucleocytoplasmic transport GO:0046822 35 0.040
aminoglycan metabolic process GO:0006022 18 0.040
compound eye photoreceptor cell differentiation GO:0001751 140 0.040
positive regulation of cellular component organization GO:0051130 156 0.039
enzyme linked receptor protein signaling pathway GO:0007167 179 0.039
response to nitrogen compound GO:1901698 90 0.039
chemosensory behavior GO:0007635 106 0.039
purine nucleoside triphosphate catabolic process GO:0009146 108 0.039
negative regulation of growth GO:0045926 84 0.039
striated muscle cell differentiation GO:0051146 90 0.038
spermatid development GO:0007286 98 0.038
cellular response to chemical stimulus GO:0070887 199 0.038
nucleoside triphosphate metabolic process GO:0009141 120 0.038
regulation of phosphate metabolic process GO:0019220 210 0.038
regulation of glial cell proliferation GO:0060251 11 0.037
cellular component disassembly GO:0022411 46 0.037
pronuclear migration GO:0035046 4 0.036
mushroom body development GO:0016319 70 0.036
determination of bilateral symmetry GO:0009855 13 0.036
camera type eye development GO:0043010 4 0.035
nitrogen compound transport GO:0071705 85 0.035
gland morphogenesis GO:0022612 145 0.034
histone h2a ubiquitination GO:0033522 2 0.034
stem cell division GO:0017145 69 0.034
cell cycle phase transition GO:0044770 140 0.034
cell adhesion GO:0007155 136 0.034
maintenance of protein location in cell GO:0032507 26 0.034
peripheral nervous system neuron differentiation GO:0048934 8 0.034
regulation of establishment of protein localization to plasma membrane GO:0090003 7 0.033
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.033
lymph gland development GO:0048542 28 0.033
dendrite morphogenesis GO:0048813 199 0.033
segment polarity determination GO:0007367 25 0.033
ubiquitin dependent protein catabolic process GO:0006511 78 0.032
nucleus localization GO:0051647 34 0.032
negative regulation of transcription dna templated GO:0045892 237 0.032
protein modification by small protein conjugation GO:0032446 79 0.032
cellular ketone metabolic process GO:0042180 24 0.032
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.032
actin cytoskeleton organization GO:0030036 206 0.032
lipid localization GO:0010876 54 0.031
innate immune response GO:0045087 144 0.031
negative regulation of tor signaling GO:0032007 5 0.031
regulation of microtubule cytoskeleton organization GO:0070507 41 0.031
sensory organ precursor cell division GO:0045035 10 0.030
carbohydrate derivative catabolic process GO:1901136 118 0.030
establishment or maintenance of cell polarity GO:0007163 167 0.030
membrane protein ectodomain proteolysis GO:0006509 5 0.030
chromosome segregation GO:0007059 157 0.030
ribonucleoside triphosphate catabolic process GO:0009203 108 0.029
ion homeostasis GO:0050801 55 0.029
positive regulation of multicellular organismal process GO:0051240 143 0.029
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.029
cardiocyte differentiation GO:0035051 29 0.029
cellular protein localization GO:0034613 160 0.029
cellular protein catabolic process GO:0044257 83 0.029
regulation of protein phosphorylation GO:0001932 64 0.029
negative regulation of neural precursor cell proliferation GO:2000178 27 0.029
lateral inhibition GO:0046331 206 0.029
anatomical structure homeostasis GO:0060249 97 0.029
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.029
cellular macromolecular complex assembly GO:0034622 153 0.028
vesicle mediated transport GO:0016192 381 0.028
negative regulation of cellular biosynthetic process GO:0031327 277 0.028
female germ line cyst encapsulation GO:0048139 8 0.028
positive regulation of cell death GO:0010942 69 0.028
negative regulation of cell death GO:0060548 81 0.028
cellular protein modification process GO:0006464 438 0.028
nucleocytoplasmic transport GO:0006913 72 0.028
regulation of cell cycle process GO:0010564 181 0.027
mesenchymal cell differentiation GO:0048762 1 0.027
axonal fasciculation GO:0007413 12 0.027
ameboidal type cell migration GO:0001667 151 0.027
ribonucleoprotein complex biogenesis GO:0022613 31 0.027
smoothened signaling pathway GO:0007224 49 0.027
torc1 signaling GO:0038202 12 0.027
mating GO:0007618 120 0.026
spermatid differentiation GO:0048515 114 0.026
pre mirna processing GO:0031054 3 0.026
anterior posterior pattern specification GO:0009952 136 0.026
establishment of planar polarity GO:0001736 87 0.025
response to glucose GO:0009749 2 0.025
cognition GO:0050890 141 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
glial cell proliferation GO:0014009 13 0.025
regulation of defense response to virus GO:0050688 14 0.025
carboxylic acid metabolic process GO:0019752 92 0.025
regulation of apoptotic process GO:0042981 130 0.025
detection of stimulus GO:0051606 156 0.025
glycosaminoglycan metabolic process GO:0030203 11 0.025
instar larval development GO:0002168 55 0.025
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.025
tissue death GO:0016271 102 0.025
regulation of receptor mediated endocytosis GO:0048259 9 0.025
regulation of axon extension GO:0030516 8 0.025
convergent extension GO:0060026 2 0.024
response to ionizing radiation GO:0010212 32 0.024
epithelial tube morphogenesis GO:0060562 88 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
purine nucleoside metabolic process GO:0042278 127 0.024
regulation of multicellular organism growth GO:0040014 40 0.024
positive regulation of phosphorylation GO:0042327 87 0.024
regulation of programmed cell death GO:0043067 152 0.024
regulation of endocytosis GO:0030100 37 0.024
sex comb development GO:0045498 8 0.023
regulation of protein kinase activity GO:0045859 51 0.023
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.023
neuroblast proliferation GO:0007405 74 0.023
germarium derived egg chamber formation GO:0007293 101 0.023
endomembrane system organization GO:0010256 119 0.023
mesoderm development GO:0007498 78 0.023
synapse organization GO:0050808 196 0.023
stress activated protein kinase signaling cascade GO:0031098 55 0.023
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.023
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.022
regulation of membrane potential GO:0042391 35 0.022
body morphogenesis GO:0010171 2 0.022
stress activated mapk cascade GO:0051403 52 0.022
regulation of cell migration GO:0030334 22 0.022
response to nutrient levels GO:0031667 114 0.022
establishment of protein localization to organelle GO:0072594 62 0.022
positive regulation of protein kinase activity GO:0045860 25 0.021
regulation of axon regeneration GO:0048679 4 0.021
gliogenesis GO:0042063 80 0.021
rubidium ion transport GO:0035826 1 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
gtp metabolic process GO:0046039 72 0.021
dendrite development GO:0016358 204 0.021
positive regulation of neuron differentiation GO:0045666 26 0.021
regulation of jnk cascade GO:0046328 40 0.021
nucleoside metabolic process GO:0009116 127 0.021
regulation of synapse structure and activity GO:0050803 128 0.021
single organism membrane organization GO:0044802 93 0.021
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.021
rhabdomere development GO:0042052 38 0.021
positive regulation of receptor mediated endocytosis GO:0048260 7 0.021
mesenchymal cell development GO:0014031 1 0.020
protein dephosphorylation GO:0006470 27 0.020
regulation of imaginal disc growth GO:0045570 26 0.020
insulin receptor signaling pathway GO:0008286 25 0.020
negative regulation of glial cell proliferation GO:0060253 6 0.020
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.020
nucleoside catabolic process GO:0009164 112 0.020
regulation of organ morphogenesis GO:2000027 78 0.020
regulation of smoothened signaling pathway GO:0008589 28 0.020
defense response to virus GO:0051607 23 0.020
positive regulation of establishment of protein localization to plasma membrane GO:0090004 3 0.020
cell proliferation GO:0008283 299 0.019
Mouse
regulation of cell projection assembly GO:0060491 30 0.019
sensory perception GO:0007600 196 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
peptidyl threonine phosphorylation GO:0018107 2 0.019
regulation of mapk cascade GO:0043408 92 0.019
positive regulation of cell development GO:0010720 61 0.019
negative regulation of developmental process GO:0051093 201 0.019
cellular polysaccharide biosynthetic process GO:0033692 7 0.019
negative regulation of epithelial cell proliferation GO:0050680 4 0.019
protein import into nucleus GO:0006606 51 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.019
germ line cyst encapsulation GO:0048138 8 0.019
connective tissue development GO:0061448 3 0.018
autophagy GO:0006914 108 0.018
negative regulation of protein catabolic process GO:0042177 17 0.018
regulation of protein complex disassembly GO:0043244 29 0.018
imaginal disc growth GO:0007446 37 0.018
chondroitin sulfate metabolic process GO:0030204 2 0.018
establishment of organelle localization GO:0051656 122 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
glycerophospholipid metabolic process GO:0006650 23 0.018
maintenance of gastrointestinal epithelium GO:0030277 3 0.018
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 2 0.018
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
response to peptide GO:1901652 29 0.018
mitotic spindle organization GO:0007052 220 0.018
digestive tract development GO:0048565 149 0.018
Worm
macromolecular complex assembly GO:0065003 256 0.018
regulation of stress activated mapk cascade GO:0032872 41 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
regulation of actin filament depolymerization GO:0030834 3 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
positive regulation of cellular protein metabolic process GO:0032270 118 0.017
production of sirna involved in rna interference GO:0030422 11 0.017
positive regulation of cellular catabolic process GO:0031331 95 0.017
regulation of establishment of protein localization GO:0070201 61 0.017
modification dependent protein catabolic process GO:0019941 78 0.017
olfactory behavior GO:0042048 97 0.017
sperm individualization GO:0007291 48 0.017
regulation of cellular response to hypoxia GO:1900037 3 0.017
negative regulation of wnt signaling pathway GO:0030178 28 0.017
regulation of actin filament length GO:0030832 27 0.017
positive regulation of phosphate metabolic process GO:0045937 139 0.017
gene silencing by mirna GO:0035195 22 0.017
cell division GO:0051301 248 0.017
regulation of cellular localization GO:0060341 136 0.017
cellular response to abiotic stimulus GO:0071214 58 0.017
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.017
germarium derived female germ line cyst encapsulation GO:0030708 8 0.016
nucleobase containing compound catabolic process GO:0034655 165 0.016
response to extracellular stimulus GO:0009991 116 0.016
specification of symmetry GO:0009799 13 0.016
regulation of catabolic process GO:0009894 170 0.016
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.016
negative regulation of organelle organization GO:0010639 56 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
regulation of response to external stimulus GO:0032101 115 0.016
signal transduction downstream of smoothened GO:0007227 5 0.016
cardiovascular system development GO:0072358 82 0.016
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.016
multicellular organismal reproductive behavior GO:0033057 110 0.016
Worm
positive regulation of kinase activity GO:0033674 25 0.016
regulation of cellular response to stress GO:0080135 89 0.016
positive regulation of notch signaling pathway GO:0045747 34 0.016
innate immune response activating signal transduction GO:0002758 2 0.016
negative regulation of synapse assembly GO:0051964 39 0.016
regulation of nucleotide catabolic process GO:0030811 48 0.016
cellular catabolic process GO:0044248 372 0.016
cytoplasmic sequestering of protein GO:0051220 4 0.016
regulation of protein localization to nucleus GO:1900180 29 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
regulation of gtp catabolic process GO:0033124 44 0.015
negative regulation of protein depolymerization GO:1901880 23 0.015
lysosomal transport GO:0007041 13 0.015
muscle cell development GO:0055001 50 0.015
muscle organ development GO:0007517 127 0.015
regulation of cell matrix adhesion GO:0001952 1 0.015
cellular response to hexose stimulus GO:0071331 1 0.015
sodium ion transport GO:0006814 22 0.015
establishment of epithelial cell apical basal polarity GO:0045198 10 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
filopodium assembly GO:0046847 33 0.015
epidermis development GO:0008544 65 0.015
heterotypic cell cell adhesion GO:0034113 1 0.015
cell fate determination GO:0001709 91 0.015
parallel actin filament bundle assembly GO:0030046 2 0.015
regulation of rho gtpase activity GO:0032319 20 0.015
actomyosin structure organization GO:0031032 56 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
mitotic nuclear division GO:0007067 213 0.015

nct disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.150
cancer DOID:162 0 0.069
organ system cancer DOID:0050686 0 0.069
large intestine cancer DOID:5672 0 0.035
gastrointestinal system cancer DOID:3119 0 0.035
intestinal cancer DOID:10155 0 0.035
colorectal cancer DOID:9256 0 0.035