Drosophila melanogaster

33 known processes

Tk (Dmel_CG14734)

Tachykinin

(Aliases: DTK,Drm-TK-4,CG14734,Drm-TK,TK-1,Dtk,dtk,Dmel\CG14734,Drm-TK-1,Drm-TK-2,Drm-TK-3,DTK1,Drm-TK-5,Drm-TK-6)

Tk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to organic substance GO:0010033 284 0.090
small molecule metabolic process GO:0044281 305 0.072
neurological system process GO:0050877 358 0.072
defense response GO:0006952 300 0.071
organonitrogen compound metabolic process GO:1901564 318 0.068
developmental growth GO:0048589 280 0.068
response to abiotic stimulus GO:0009628 341 0.064
response to external biotic stimulus GO:0043207 293 0.059
growth GO:0040007 359 0.058
negative regulation of response to stimulus GO:0048585 258 0.053
negative regulation of cellular metabolic process GO:0031324 382 0.052
response to biotic stimulus GO:0009607 294 0.048
response to other organism GO:0051707 293 0.046
regulation of immune response GO:0050776 118 0.043
negative regulation of signal transduction GO:0009968 206 0.043
immune response GO:0006955 246 0.043
regulation of response to stress GO:0080134 200 0.043
response to nutrient levels GO:0031667 114 0.042
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.041
positive regulation of response to stimulus GO:0048584 323 0.040
oxoacid metabolic process GO:0043436 103 0.040
mating GO:0007618 120 0.040
negative regulation of cellular biosynthetic process GO:0031327 277 0.040
negative regulation of gene expression GO:0010629 387 0.040
intracellular signal transduction GO:0035556 300 0.040
vesicle mediated transport GO:0016192 381 0.038
cation transport GO:0006812 110 0.038
central nervous system development GO:0007417 201 0.037
regulation of intracellular signal transduction GO:1902531 236 0.037
regulation of immune system process GO:0002682 176 0.037
ion transport GO:0006811 145 0.037
cellular ketone metabolic process GO:0042180 24 0.037
response to bacterium GO:0009617 198 0.036
regionalization GO:0003002 416 0.036
negative regulation of cell communication GO:0010648 223 0.036
response to oxygen containing compound GO:1901700 200 0.036
organic acid metabolic process GO:0006082 103 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
positive regulation of signal transduction GO:0009967 223 0.035
negative regulation of cellular component organization GO:0051129 108 0.035
metal ion transport GO:0030001 74 0.034
epithelial cell differentiation GO:0030855 322 0.033
carboxylic acid metabolic process GO:0019752 92 0.033
single organism biosynthetic process GO:0044711 206 0.032
regulation of defense response GO:0031347 102 0.032
positive regulation of signaling GO:0023056 243 0.032
cellular amino acid metabolic process GO:0006520 61 0.032
death GO:0016265 284 0.032
g protein coupled receptor signaling pathway GO:0007186 136 0.031
response to extracellular stimulus GO:0009991 116 0.030
spermatogenesis GO:0007283 200 0.029
positive regulation of cell communication GO:0010647 250 0.029
negative regulation of rna metabolic process GO:0051253 251 0.029
single organism intracellular transport GO:1902582 207 0.029
regulation of cellular ketone metabolic process GO:0010565 3 0.029
negative regulation of developmental process GO:0051093 201 0.029
dorsal ventral pattern formation GO:0009953 133 0.029
negative regulation of biosynthetic process GO:0009890 277 0.028
forebrain development GO:0030900 2 0.028
cell death GO:0008219 279 0.027
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.027
eye development GO:0001654 323 0.027
cellular response to chemical stimulus GO:0070887 199 0.027
male gamete generation GO:0048232 201 0.026
rhythmic behavior GO:0007622 76 0.026
macromolecular complex assembly GO:0065003 256 0.026
locomotory behavior GO:0007626 176 0.026
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
regulation of response to external stimulus GO:0032101 115 0.026
negative regulation of rna biosynthetic process GO:1902679 240 0.026
cell division GO:0051301 248 0.026
immune effector process GO:0002252 98 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
regulation of cell cycle GO:0051726 291 0.025
cognition GO:0050890 141 0.025
response to endogenous stimulus GO:0009719 119 0.025
regulation of localization GO:0032879 275 0.025
l amino acid import GO:0043092 2 0.025
immune system process GO:0002376 347 0.025
negative regulation of signaling GO:0023057 219 0.024
endocytosis GO:0006897 310 0.024
purine ribonucleotide metabolic process GO:0009150 145 0.024
divalent metal ion transport GO:0070838 26 0.024
embryonic development via the syncytial blastoderm GO:0001700 148 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
organelle fission GO:0048285 340 0.024
cellular homeostasis GO:0019725 80 0.024
axonogenesis GO:0007409 290 0.024
response to alcohol GO:0097305 95 0.024
response to radiation GO:0009314 155 0.024
regulation of protein metabolic process GO:0051246 256 0.024
immune response regulating signaling pathway GO:0002764 2 0.024
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.023
response to nitrogen compound GO:1901698 90 0.023
regulation of developmental growth GO:0048638 174 0.023
mitotic nuclear division GO:0007067 213 0.023
camera type eye development GO:0043010 4 0.023
nucleotide metabolic process GO:0009117 161 0.022
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
ameboidal type cell migration GO:0001667 151 0.022
regulation of immune effector process GO:0002697 52 0.022
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
response to lipopolysaccharide GO:0032496 4 0.022
regulation of growth GO:0040008 233 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
amine metabolic process GO:0009308 12 0.022
single organism behavior GO:0044708 391 0.022
organic substance catabolic process GO:1901575 308 0.022
nitrogen compound transport GO:0071705 85 0.022
hindbrain development GO:0030902 2 0.022
actin cytoskeleton organization GO:0030036 206 0.021
kidney development GO:0001822 3 0.021
protein modification process GO:0036211 438 0.021
sensory organ morphogenesis GO:0090596 260 0.021
response to glucose GO:0009749 2 0.021
cellular catabolic process GO:0044248 372 0.021
phosphorylation GO:0016310 294 0.021
organic substance transport GO:0071702 257 0.021
response to light stimulus GO:0009416 124 0.021
small molecule biosynthetic process GO:0044283 37 0.020
appendage development GO:0048736 401 0.020
negative regulation of multicellular organismal process GO:0051241 142 0.020
response to organic cyclic compound GO:0014070 89 0.020
multicellular organismal aging GO:0010259 140 0.020
single organism catabolic process GO:0044712 228 0.020
intracellular transport GO:0046907 228 0.020
adult behavior GO:0030534 137 0.020
regulation of catalytic activity GO:0050790 185 0.020
chemical homeostasis GO:0048878 92 0.020
chemotaxis GO:0006935 249 0.020
ribonucleotide metabolic process GO:0009259 145 0.020
regulation of transport GO:0051049 181 0.020
organophosphate metabolic process GO:0019637 195 0.020
catabolic process GO:0009056 409 0.019
nuclear division GO:0000280 332 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
regulation of molecular function GO:0065009 217 0.019
negative regulation of defense response GO:0031348 35 0.019
digestive tract development GO:0048565 149 0.019
actin filament based process GO:0030029 220 0.019
organic hydroxy compound metabolic process GO:1901615 83 0.019
regulation of cell cycle process GO:0010564 181 0.019
organonitrogen compound biosynthetic process GO:1901566 117 0.019
organelle assembly GO:0070925 198 0.019
cellular cation homeostasis GO:0030003 38 0.019
homeostatic process GO:0042592 199 0.019
heart process GO:0003015 37 0.019
carbohydrate metabolic process GO:0005975 82 0.019
cuticle development GO:0042335 86 0.019
posttranscriptional regulation of gene expression GO:0010608 145 0.019
response to organonitrogen compound GO:0010243 75 0.019
body morphogenesis GO:0010171 2 0.019
positive regulation of molecular function GO:0044093 136 0.019
proteolysis GO:0006508 192 0.018
circadian behavior GO:0048512 76 0.018
cellular amine metabolic process GO:0044106 12 0.018
ovarian follicle cell development GO:0030707 248 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
purine containing compound metabolic process GO:0072521 155 0.018
immune response activating signal transduction GO:0002757 2 0.018
regulation of mitotic cell cycle GO:0007346 190 0.018
response to ethanol GO:0045471 59 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
spermatid differentiation GO:0048515 114 0.017
biological adhesion GO:0022610 138 0.017
purine nucleotide metabolic process GO:0006163 146 0.017
cellular ion homeostasis GO:0006873 39 0.017
regulation of anatomical structure morphogenesis GO:0022603 242 0.017
cell cycle phase transition GO:0044770 140 0.017
phagocytosis GO:0006909 215 0.017
single organism membrane organization GO:0044802 93 0.017
cellular response to carbohydrate stimulus GO:0071322 4 0.017
tube development GO:0035295 244 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
localization of cell GO:0051674 257 0.017
regulation of organelle organization GO:0033043 196 0.017
innate immune response GO:0045087 144 0.017
regulation of behavior GO:0050795 75 0.017
cation homeostasis GO:0055080 51 0.017
cellular protein modification process GO:0006464 438 0.017
response to organophosphorus GO:0046683 2 0.017
signal transduction by phosphorylation GO:0023014 107 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.016
multi organism behavior GO:0051705 175 0.016
response to monosaccharide GO:0034284 4 0.016
endomembrane system organization GO:0010256 119 0.016
positive regulation of cell migration GO:0030335 2 0.016
epithelial cell development GO:0002064 274 0.016
learning or memory GO:0007611 141 0.016
positive regulation of immune system process GO:0002684 68 0.016
nucleoside triphosphate metabolic process GO:0009141 120 0.016
regulation of gene expression epigenetic GO:0040029 128 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
monocarboxylic acid transport GO:0015718 3 0.015
defense response to other organism GO:0098542 225 0.015
embryonic morphogenesis GO:0048598 206 0.015
response to alkaloid GO:0043279 26 0.015
pattern recognition receptor signaling pathway GO:0002221 2 0.015
establishment of localization in cell GO:0051649 402 0.015
regulation of cellular component biogenesis GO:0044087 201 0.015
protein complex biogenesis GO:0070271 201 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
mesenchymal cell development GO:0014031 1 0.015
lipid metabolic process GO:0006629 121 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
negative regulation of immune system process GO:0002683 50 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
negative regulation of organelle organization GO:0010639 56 0.015
mesenchymal cell differentiation GO:0048762 1 0.015
cation transmembrane transport GO:0098655 88 0.015
single organism carbohydrate metabolic process GO:0044723 72 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
adult locomotory behavior GO:0008344 76 0.015
wing disc morphogenesis GO:0007472 344 0.014
response to hexose GO:0009746 3 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.014
regulation of phosphorus metabolic process GO:0051174 210 0.014
heterocycle catabolic process GO:0046700 166 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
positive regulation of cellular amine metabolic process GO:0033240 0 0.014
organic cyclic compound catabolic process GO:1901361 168 0.014
cellular amide metabolic process GO:0043603 80 0.014
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.014
response to temperature stimulus GO:0009266 106 0.014
regulation of nervous system development GO:0051960 248 0.014
cell adhesion GO:0007155 136 0.014
gene silencing by rna GO:0031047 57 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
digestive system development GO:0055123 149 0.014
cellular response to organic substance GO:0071310 132 0.014
multi multicellular organism process GO:0044706 123 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.014
tissue migration GO:0090130 155 0.014
imaginal disc derived appendage morphogenesis GO:0035114 395 0.014
sensory perception GO:0007600 196 0.014
regulation of cell death GO:0010941 173 0.014
transcription from rna polymerase ii promoter GO:0006366 368 0.014
anion homeostasis GO:0055081 3 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.013
lateral inhibition GO:0046331 206 0.013
protein phosphorylation GO:0006468 169 0.013
reproductive behavior GO:0019098 122 0.013
rna processing GO:0006396 147 0.013
connective tissue development GO:0061448 3 0.013
innate immune response activating signal transduction GO:0002758 2 0.013
vitamin biosynthetic process GO:0009110 1 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
positive regulation of cellular protein metabolic process GO:0032270 118 0.013
positive regulation of gene expression GO:0010628 290 0.013
sodium dependent phosphate transport GO:0044341 2 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
ion homeostasis GO:0050801 55 0.013
sensory perception of pain GO:0019233 4 0.013
camera type eye morphogenesis GO:0048593 2 0.013
heart contraction GO:0060047 26 0.013
regulation of cell differentiation GO:0045595 302 0.013
tube morphogenesis GO:0035239 191 0.013
eye morphogenesis GO:0048592 260 0.013
retina development in camera type eye GO:0060041 4 0.013
positive regulation of cell motility GO:2000147 3 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
programmed cell death GO:0012501 257 0.013
response to heat GO:0009408 63 0.013
positive regulation of protein metabolic process GO:0051247 128 0.013
regulation of proteolysis GO:0030162 87 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
mapk cascade GO:0000165 107 0.013
nephron tubule development GO:0072080 3 0.013
regulation of cell shape GO:0008360 113 0.013
negative regulation of cell death GO:0060548 81 0.013
inorganic ion transmembrane transport GO:0098660 73 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
positive regulation of phosphate metabolic process GO:0045937 139 0.012
respiratory system development GO:0060541 213 0.012
cellular chemical homeostasis GO:0055082 40 0.012
cell motility GO:0048870 251 0.012
negative regulation of cell differentiation GO:0045596 143 0.012
protein complex assembly GO:0006461 200 0.012
activation of innate immune response GO:0002218 4 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
mushroom body development GO:0016319 70 0.012
chitin based cuticle development GO:0040003 49 0.012
negative regulation of protein metabolic process GO:0051248 85 0.012
cell migration GO:0016477 238 0.012
polyol biosynthetic process GO:0046173 3 0.012
cellular carbohydrate metabolic process GO:0044262 22 0.012
apoptotic process GO:0006915 159 0.012
larval behavior GO:0030537 42 0.012
regulation of innate immune response GO:0045088 71 0.012
response to copper ion GO:0046688 4 0.012
compound eye development GO:0048749 307 0.012
aromatic compound catabolic process GO:0019439 166 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
flight behavior GO:0007629 26 0.012
male meiosis GO:0007140 52 0.012
behavioral response to ethanol GO:0048149 49 0.012
blood circulation GO:0008015 26 0.012
memory GO:0007613 94 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
regulation of apoptotic process GO:0042981 130 0.011
dorsal closure GO:0007391 79 0.011
nucleoside metabolic process GO:0009116 127 0.011
circadian rhythm GO:0007623 105 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
eye pigment biosynthetic process GO:0006726 32 0.011
stem cell proliferation GO:0072089 88 0.011
imaginal disc pattern formation GO:0007447 91 0.011
negative regulation of developmental growth GO:0048640 64 0.011
response to hypoxia GO:0001666 53 0.011
developmental maturation GO:0021700 172 0.011
protein localization GO:0008104 284 0.011
regulation of response to biotic stimulus GO:0002831 63 0.011
gland development GO:0048732 191 0.011
stem cell development GO:0048864 79 0.011
organic hydroxy compound biosynthetic process GO:1901617 21 0.011
divalent inorganic cation transport GO:0072511 30 0.011
meiotic cell cycle GO:0051321 171 0.011
calcium ion transport GO:0006816 24 0.011
stem cell differentiation GO:0048863 117 0.011
positive regulation of immune response GO:0050778 63 0.011
dendrite morphogenesis GO:0048813 199 0.011
regulation of hormone levels GO:0010817 40 0.011
appendage morphogenesis GO:0035107 397 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
tissue morphogenesis GO:0048729 297 0.011
anion transport GO:0006820 41 0.011
monovalent inorganic cation transport GO:0015672 40 0.011
negative regulation of growth GO:0045926 84 0.011
negative regulation of homeostatic process GO:0032845 2 0.011
alcohol metabolic process GO:0006066 25 0.011
spindle organization GO:0007051 253 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
jak stat cascade GO:0007259 49 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
chromosome segregation GO:0007059 157 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
epithelium migration GO:0090132 148 0.011
regulation of cellular response to stress GO:0080135 89 0.011
response to oxygen levels GO:0070482 59 0.011
guanosine containing compound catabolic process GO:1901069 74 0.011
neuron projection guidance GO:0097485 241 0.011
aging GO:0007568 143 0.011
positive regulation of developmental process GO:0051094 143 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
oligosaccharide transport GO:0015772 2 0.011
axon guidance GO:0007411 233 0.011
secretion GO:0046903 109 0.011
learning GO:0007612 75 0.011
nucleoside phosphate catabolic process GO:1901292 110 0.011
cellular macromolecule localization GO:0070727 220 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
kidney epithelium development GO:0072073 3 0.010
locomotor rhythm GO:0045475 56 0.010
regulation of cell morphogenesis GO:0022604 163 0.010
long term memory GO:0007616 62 0.010
cellular protein localization GO:0034613 160 0.010
telencephalon development GO:0021537 2 0.010
small gtpase mediated signal transduction GO:0007264 88 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
peptidyl threonine phosphorylation GO:0018107 2 0.010
single organism cellular localization GO:1902580 180 0.010
nuclear transport GO:0051169 72 0.010
positive regulation of phosphorylation GO:0042327 87 0.010
synapse assembly GO:0007416 143 0.010
fat soluble vitamin metabolic process GO:0006775 1 0.010
purine ribonucleoside metabolic process GO:0046128 127 0.010
response to wounding GO:0009611 94 0.010
defense response to bacterium GO:0042742 178 0.010
regulation of mapk cascade GO:0043408 92 0.010
brain development GO:0007420 120 0.010
determination of adult lifespan GO:0008340 137 0.010

Tk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.044
musculoskeletal system disease DOID:17 0 0.028
nervous system disease DOID:863 0 0.022
disease of metabolism DOID:0014667 0 0.021
connective tissue disease DOID:65 0 0.018
sensory system disease DOID:0050155 0 0.015
bone disease DOID:0080001 0 0.014
inherited metabolic disorder DOID:655 0 0.014
cardiovascular system disease DOID:1287 0 0.013
eye and adnexa disease DOID:1492 0 0.012
eye disease DOID:5614 0 0.012
central nervous system disease DOID:331 0 0.011