Drosophila melanogaster

205 known processes

AGO2 (Dmel_CG7439)

Argonaute 2

(Aliases: ago,AG02,Dm Ago2,CG7739,AGO 2,ago-2,CG7439,dAgo2,eIF2C2,Dmel\CG7439,ago2,Ago-2,CG13452,dAGO2,Ago2)

AGO2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002816 3 0.999
immune system process GO:0002376 347 0.962
defense response to other organism GO:0098542 225 0.960
immune response GO:0006955 246 0.948
humoral immune response GO:0006959 117 0.913
response to other organism GO:0051707 293 0.893
innate immune response GO:0045087 144 0.872
chromosome organization GO:0051276 360 0.840
response to bacterium GO:0009617 198 0.830
defense response GO:0006952 300 0.826
response to biotic stimulus GO:0009607 294 0.812
response to external biotic stimulus GO:0043207 293 0.766
regulation of defense response to virus by host GO:0050691 10 0.743
regulation of humoral immune response GO:0002920 51 0.730
defense response to bacterium GO:0042742 178 0.724
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.706
antibacterial humoral response GO:0019731 44 0.641
positive regulation of macromolecule metabolic process GO:0010604 405 0.630
negative regulation of cellular biosynthetic process GO:0031327 277 0.626
organelle fission GO:0048285 340 0.625
negative regulation of cellular metabolic process GO:0031324 382 0.595
response to ionizing radiation GO:0010212 32 0.574
cellular protein modification process GO:0006464 438 0.530
antimicrobial humoral response GO:0019730 99 0.479
positive regulation of biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0006965 3 0.468
regulation of intracellular signal transduction GO:1902531 236 0.466
negative regulation of rna biosynthetic process GO:1902679 240 0.419
establishment of localization in cell GO:0051649 402 0.414
developmental maturation GO:0021700 172 0.403
antimicrobial peptide production GO:0002775 46 0.395
regulation of response to stress GO:0080134 200 0.393
positive regulation of peptidase activity GO:0010952 29 0.365
nuclear division GO:0000280 332 0.359
defense response to gram negative bacterium GO:0050829 94 0.355
positive regulation of defense response to virus by host GO:0002230 10 0.350
regulation of cellular protein metabolic process GO:0032268 243 0.344
vesicle mediated transport GO:0016192 381 0.343
dna metabolic process GO:0006259 227 0.340
negative regulation of cell cycle phase transition GO:1901988 103 0.335
meiotic cell cycle GO:0051321 171 0.329
chromosome segregation GO:0007059 157 0.293
single organism intracellular transport GO:1902582 207 0.288
regulation of antimicrobial humoral response GO:0002759 50 0.284
regulation of catalytic activity GO:0050790 185 0.264
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.260
meiotic chromosome segregation GO:0045132 59 0.260
chromatin organization GO:0006325 207 0.238
negative regulation of intracellular signal transduction GO:1902532 57 0.232
organic substance transport GO:0071702 257 0.229
regulation of response to biotic stimulus GO:0002831 63 0.224
endocytosis GO:0006897 310 0.213
positive regulation of antifungal peptide biosynthetic process GO:0006967 5 0.199
positive regulation of cellular protein metabolic process GO:0032270 118 0.194
intrinsic apoptotic signaling pathway GO:0097193 16 0.184
mitotic nuclear division GO:0007067 213 0.180
cellular response to dna damage stimulus GO:0006974 223 0.179
regulation of multi organism process GO:0043900 131 0.176
protein localization GO:0008104 284 0.175
dna conformation change GO:0071103 105 0.170
dna packaging GO:0006323 91 0.167
biosynthetic process of antibacterial peptides active against gram positive bacteria GO:0002815 3 0.165
negative regulation of defense response to bacterium GO:1900425 7 0.163
regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002813 14 0.160
response to radiation GO:0009314 155 0.156
cellular response to starvation GO:0009267 61 0.153
mitotic spindle organization GO:0007052 220 0.151
response to virus GO:0009615 28 0.151
positive regulation of macroautophagy GO:0016239 8 0.150
regulation of macroautophagy GO:0016241 15 0.149
intracellular signal transduction GO:0035556 300 0.148
mitotic cell cycle checkpoint GO:0007093 88 0.148
sister chromatid segregation GO:0000819 92 0.146
positive regulation of hydrolase activity GO:0051345 78 0.141
actin cytoskeleton organization GO:0030036 206 0.140
regulation of defense response to virus GO:0050688 14 0.135
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.134
activation of cysteine type endopeptidase activity GO:0097202 17 0.130
intracellular transport GO:0046907 228 0.129
response to organic substance GO:0010033 284 0.128
positive regulation of endopeptidase activity GO:0010950 26 0.127
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.126
organelle localization GO:0051640 148 0.126
dna damage checkpoint GO:0000077 78 0.125
innate immune response activating signal transduction GO:0002758 2 0.124
neuron remodeling GO:0016322 29 0.123
defense response to virus GO:0051607 23 0.123
positive regulation of catalytic activity GO:0043085 118 0.120
mitotic sister chromatid segregation GO:0000070 87 0.115
positive regulation of response to stimulus GO:0048584 323 0.115
cellular response to chemical stimulus GO:0070887 199 0.114
positive regulation of response to extracellular stimulus GO:0032106 8 0.110
response to organonitrogen compound GO:0010243 75 0.110
regulation of response to nutrient levels GO:0032107 18 0.109
immune effector process GO:0002252 98 0.108
positive regulation of response to nutrient levels GO:0032109 8 0.106
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.105
positive regulation of protein metabolic process GO:0051247 128 0.105
negative regulation of organelle organization GO:0010639 56 0.104
heterochromatin organization GO:0070828 25 0.103
regulation of immune response GO:0050776 118 0.103
negative regulation of mitotic cell cycle GO:0045930 109 0.103
execution phase of apoptosis GO:0097194 7 0.102
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.102
regulation of catabolic process GO:0009894 170 0.101
response to starvation GO:0042594 97 0.101
signal transduction in response to dna damage GO:0042770 3 0.099
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.099
small rna loading onto risc GO:0070922 6 0.098
regulation of antimicrobial peptide production GO:0002784 44 0.098
positive regulation of antimicrobial humoral response GO:0002760 28 0.096
regulation of response to extracellular stimulus GO:0032104 18 0.095
protein heterooligomerization GO:0051291 4 0.094
negative regulation of cell cycle process GO:0010948 109 0.093
centrosome duplication GO:0051298 121 0.093
positive regulation of proteolysis GO:0045862 52 0.093
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.093
regulation of protein metabolic process GO:0051246 256 0.091
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.091
macromolecular complex assembly GO:0065003 256 0.090
single organism behavior GO:0044708 391 0.090
positive regulation of humoral immune response GO:0002922 28 0.089
positive regulation of antibacterial peptide production GO:0002803 20 0.088
regulation of defense response GO:0031347 102 0.088
centrosome cycle GO:0007098 137 0.087
regionalization GO:0003002 416 0.087
regulation of peptidoglycan recognition protein signaling pathway GO:0061058 4 0.087
digestive tract development GO:0048565 149 0.087
appendage development GO:0048736 401 0.086
response to peptidoglycan GO:0032494 2 0.084
positive regulation of intracellular signal transduction GO:1902533 116 0.084
regulation of cell cycle GO:0051726 291 0.084
nitrogen compound transport GO:0071705 85 0.084
regulation of hydrolase activity GO:0051336 97 0.083
dna integrity checkpoint GO:0031570 81 0.083
positive regulation of antifungal peptide production GO:0002804 6 0.081
negative regulation of signal transduction GO:0009968 206 0.081
negative regulation of biosynthetic process GO:0009890 277 0.081
telencephalon development GO:0021537 2 0.080
positive regulation of gene expression GO:0010628 290 0.080
regulation of antifungal peptide biosynthetic process GO:0002810 5 0.078
protein modification process GO:0036211 438 0.077
regulation of molecular function GO:0065009 217 0.076
antimicrobial peptide biosynthetic process GO:0002777 38 0.075
protein complex biogenesis GO:0070271 201 0.075
positive regulation of response to external stimulus GO:0032103 44 0.075
regulation of organelle organization GO:0033043 196 0.072
regulation of response to external stimulus GO:0032101 115 0.072
negative regulation of response to stimulus GO:0048585 258 0.072
forebrain development GO:0030900 2 0.071
carbohydrate derivative metabolic process GO:1901135 217 0.071
production of molecular mediator of immune response GO:0002440 46 0.071
response to light stimulus GO:0009416 124 0.070
negative regulation of developmental process GO:0051093 201 0.069
imaginal disc derived appendage morphogenesis GO:0035114 395 0.069
chromatin modification GO:0016568 147 0.069
negative regulation of transcription dna templated GO:0045892 237 0.068
cell cycle checkpoint GO:0000075 95 0.066
pattern recognition receptor signaling pathway GO:0002221 2 0.066
brain development GO:0007420 120 0.065
antifungal peptide production GO:0002781 7 0.065
posttranscriptional gene silencing GO:0016441 46 0.065
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.065
death GO:0016265 284 0.065
positive regulation of antibacterial peptide biosynthetic process GO:0006963 20 0.064
chemotaxis GO:0006935 249 0.063
regulation of cell death GO:0010941 173 0.063
spindle organization GO:0007051 253 0.062
endosomal transport GO:0016197 44 0.062
melanin metabolic process GO:0006582 47 0.061
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.061
posttranscriptional regulation of gene expression GO:0010608 145 0.061
organonitrogen compound metabolic process GO:1901564 318 0.061
regulation of phosphate metabolic process GO:0019220 210 0.061
multicellular organismal aging GO:0010259 140 0.061
cell division GO:0051301 248 0.061
negative regulation of signaling GO:0023057 219 0.061
regulation of cellular catabolic process GO:0031329 157 0.060
activation of innate immune response GO:0002218 4 0.060
regulation of cysteine type endopeptidase activity GO:2000116 27 0.060
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.058
meiotic nuclear division GO:0007126 151 0.058
response to oxygen radical GO:0000305 3 0.057
positive regulation of molecular function GO:0044093 136 0.057
defense response to fungus GO:0050832 48 0.057
macroautophagy GO:0016236 42 0.057
positive regulation of autophagy GO:0010508 21 0.057
cell cycle phase transition GO:0044770 140 0.057
positive regulation of phosphate metabolic process GO:0045937 139 0.057
mitotic dna damage checkpoint GO:0044773 74 0.056
regulation of antibacterial peptide production GO:0002786 22 0.054
chromosome condensation GO:0030261 41 0.053
positive regulation of catabolic process GO:0009896 105 0.053
epithelial cell differentiation GO:0030855 322 0.053
positive regulation of transcription dna templated GO:0045893 266 0.052
cognition GO:0050890 141 0.052
mitotic sister chromatid separation GO:0051306 30 0.051
regulation of innate immune response GO:0045088 71 0.051
positive regulation of antimicrobial peptide biosynthetic process GO:0002807 26 0.051
positive regulation of defense response GO:0031349 59 0.050
dendrite morphogenesis GO:0048813 199 0.050
ectopic germ cell programmed cell death GO:0035234 8 0.050
metaphase plate congression GO:0051310 19 0.050
response to toxic substance GO:0009636 22 0.050
regulation of peptidase activity GO:0052547 39 0.050
regulation of cellular response to stress GO:0080135 89 0.049
neuron projection guidance GO:0097485 241 0.049
regulation of antibacterial peptide biosynthetic process GO:0002808 22 0.048
chromosome localization GO:0050000 20 0.048
phagocytosis GO:0006909 215 0.048
cell migration GO:0016477 238 0.047
cell motility GO:0048870 251 0.047
defense response to gram positive bacterium GO:0050830 41 0.047
chromatin remodeling GO:0006338 72 0.047
regulation of localization GO:0032879 275 0.047
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.046
retinal cell programmed cell death GO:0046666 25 0.046
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.046
epithelial cell development GO:0002064 274 0.045
regulation of phosphorylation GO:0042325 147 0.045
negative regulation of cell death GO:0060548 81 0.045
chromatin silencing GO:0006342 76 0.045
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.045
neuron maturation GO:0042551 31 0.044
regulation of endopeptidase activity GO:0052548 36 0.044
positive regulation of cell communication GO:0010647 250 0.044
single organism catabolic process GO:0044712 228 0.044
ovarian follicle cell development GO:0030707 248 0.043
detection of abiotic stimulus GO:0009582 66 0.043
transcription from rna polymerase ii promoter GO:0006366 368 0.043
dorsal ventral pattern formation GO:0009953 133 0.043
cell maturation GO:0048469 144 0.042
cellular response to organic substance GO:0071310 132 0.042
apoptotic process GO:0006915 159 0.042
chromatin assembly or disassembly GO:0006333 52 0.042
cell death GO:0008219 279 0.042
posttranscriptional gene silencing by rna GO:0035194 45 0.040
retina development in camera type eye GO:0060041 4 0.040
mitotic dna integrity checkpoint GO:0044774 75 0.040
protein catabolic process GO:0030163 101 0.040
oocyte fate determination GO:0030716 27 0.040
mitotic cell cycle embryonic GO:0045448 38 0.040
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.039
regulation of mitotic cell cycle phase transition GO:1901990 130 0.039
chromosome separation GO:0051304 42 0.039
positive regulation of rna metabolic process GO:0051254 271 0.039
oocyte differentiation GO:0009994 145 0.039
response to oxygen containing compound GO:1901700 200 0.038
regulation of nuclear division GO:0051783 58 0.038
cell proliferation GO:0008283 299 0.038
positive regulation of immune response GO:0050778 63 0.038
nucleotide metabolic process GO:0009117 161 0.038
programmed cell death GO:0012501 257 0.037
wing disc morphogenesis GO:0007472 344 0.037
embryonic morphogenesis GO:0048598 206 0.037
cellular response to extracellular stimulus GO:0031668 64 0.037
proteasomal protein catabolic process GO:0010498 59 0.037
respiratory system development GO:0060541 213 0.036
regulation of transport GO:0051049 181 0.036
anatomical structure homeostasis GO:0060249 97 0.036
peptide metabolic process GO:0006518 80 0.036
antibacterial peptide production GO:0002778 22 0.035
response to nutrient levels GO:0031667 114 0.035
localization of cell GO:0051674 257 0.035
cellular response to external stimulus GO:0071496 66 0.035
regulation of mitosis GO:0007088 56 0.034
germ cell migration GO:0008354 43 0.034
positive regulation of transport GO:0051050 92 0.034
regulation of mapk cascade GO:0043408 92 0.034
regulation of proteolysis GO:0030162 87 0.034
regulation of multicellular organism growth GO:0040014 40 0.034
regulation of wnt signaling pathway GO:0030111 68 0.034
metaphase anaphase transition of cell cycle GO:0044784 28 0.034
post embryonic appendage morphogenesis GO:0035120 385 0.034
regulation of developmental growth GO:0048638 174 0.033
purine nucleoside metabolic process GO:0042278 127 0.033
antifungal peptide biosynthetic process GO:0002783 5 0.032
pole cell development GO:0007277 26 0.032
negative regulation of gene expression GO:0010629 387 0.032
regulation of cellular component size GO:0032535 98 0.031
cell fate determination GO:0001709 91 0.031
neural retina development GO:0003407 4 0.031
regulation of protein phosphorylation GO:0001932 64 0.031
biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0002812 14 0.031
negative regulation of cell cycle GO:0045786 116 0.031
gastrulation GO:0007369 70 0.030
negative regulation of cell division GO:0051782 17 0.030
axon development GO:0061564 297 0.030
regulation of defense response to fungus GO:1900150 6 0.030
positive regulation of antimicrobial peptide production GO:0002225 28 0.030
organic substance catabolic process GO:1901575 308 0.030
positive regulation of mapk cascade GO:0043410 63 0.030
positive regulation of defense response to bacterium GO:1900426 23 0.030
small molecule metabolic process GO:0044281 305 0.030
multicellular organismal reproductive behavior GO:0033057 110 0.029
negative regulation of cell differentiation GO:0045596 143 0.029
phosphorylation GO:0016310 294 0.029
asymmetric protein localization GO:0008105 33 0.028
tissue morphogenesis GO:0048729 297 0.028
regulation of cell cycle process GO:0010564 181 0.028
peptide biosynthetic process GO:0043043 42 0.028
cellular response to nutrient levels GO:0031669 62 0.028
regulation of immune system process GO:0002682 176 0.028
positive regulation of cellular catabolic process GO:0031331 95 0.028
digestive tract morphogenesis GO:0048546 127 0.027
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.027
single organism biosynthetic process GO:0044711 206 0.027
secondary metabolic process GO:0019748 75 0.026
regulation of mitotic sister chromatid segregation GO:0033047 28 0.026
mitotic cell cycle phase transition GO:0044772 138 0.026
germarium derived oocyte fate determination GO:0007294 26 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
imaginal disc derived appendage development GO:0048737 399 0.026
regulation of immune effector process GO:0002697 52 0.026
imaginal disc derived wing morphogenesis GO:0007476 337 0.026
regulation of phosphorus metabolic process GO:0051174 210 0.026
regulation of mitotic cell cycle GO:0007346 190 0.026
proteolysis GO:0006508 192 0.025
positive regulation of multi organism process GO:0043902 40 0.025
maintenance of gastrointestinal epithelium GO:0030277 3 0.025
positive regulation of response to biotic stimulus GO:0002833 31 0.025
stress activated mapk cascade GO:0051403 52 0.025
positive regulation of biosynthetic process of antibacterial peptides active against gram negative bacteria GO:0006964 12 0.025
central nervous system development GO:0007417 201 0.025
gene silencing GO:0016458 138 0.025
cellular response to abiotic stimulus GO:0071214 58 0.025
detection of light stimulus GO:0009583 58 0.025
multi multicellular organism process GO:0044706 123 0.024
amide biosynthetic process GO:0043604 42 0.024
centrosome organization GO:0051297 163 0.024
peptidoglycan recognition protein signaling pathway GO:0061057 16 0.024
vesicle localization GO:0051648 55 0.024
cell type specific apoptotic process GO:0097285 38 0.024
establishment of chromosome localization GO:0051303 20 0.024
microtubule organizing center organization GO:0031023 168 0.024
intracellular protein transport GO:0006886 104 0.024
regulation of cell division GO:0051302 72 0.023
cytoskeleton dependent intracellular transport GO:0030705 44 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.023
response to superoxide GO:0000303 3 0.023
limb development GO:0060173 1 0.023
negative regulation of innate immune response GO:0045824 30 0.023
actin filament organization GO:0007015 126 0.022
positive regulation of signal transduction GO:0009967 223 0.022
ribonucleoside triphosphate metabolic process GO:0009199 119 0.022
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.022
catabolic process GO:0009056 409 0.022
neurological system process GO:0050877 358 0.022
positive regulation of apoptotic signaling pathway GO:2001235 4 0.022
telomere maintenance GO:0000723 21 0.022
ras protein signal transduction GO:0007265 88 0.022
positive regulation of signaling GO:0023056 243 0.021
purine nucleoside catabolic process GO:0006152 112 0.021
gastrulation with mouth forming first GO:0001703 36 0.021
response to alkaloid GO:0043279 26 0.021
purine nucleotide catabolic process GO:0006195 109 0.021
aging GO:0007568 143 0.021
head development GO:0060322 135 0.021
positive regulation of cellular component biogenesis GO:0044089 80 0.021
cellular catabolic process GO:0044248 372 0.021
developmental programmed cell death GO:0010623 138 0.021
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.020
cellular protein localization GO:0034613 160 0.020
apoptotic signaling pathway GO:0097190 27 0.020
cation transport GO:0006812 110 0.020
negative regulation of cellular component organization GO:0051129 108 0.020
chromatin assembly GO:0031497 48 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
carboxylic acid metabolic process GO:0019752 92 0.020
regulation of metaphase anaphase transition of cell cycle GO:1902099 26 0.020
reproductive structure development GO:0048608 74 0.020
regulation of transcription by chromatin organization GO:0034401 3 0.019
purine ribonucleoside catabolic process GO:0046130 112 0.019
covalent chromatin modification GO:0016569 106 0.019
regulation of proteasomal protein catabolic process GO:0061136 39 0.019
oxidation reduction process GO:0055114 123 0.019
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.019
carboxylic acid transport GO:0046942 18 0.019
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.019
regulation of anatomical structure size GO:0090066 163 0.019
amino acid transport GO:0006865 12 0.019
axonogenesis GO:0007409 290 0.018
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.018
response to dsrna GO:0043331 15 0.018
stem cell proliferation GO:0072089 88 0.018
negative regulation of stem cell proliferation GO:2000647 30 0.018
open tracheal system development GO:0007424 204 0.018
zymogen activation GO:0031638 20 0.018
response to lipopolysaccharide GO:0032496 4 0.018
organophosphate metabolic process GO:0019637 195 0.018
telomere organization GO:0032200 21 0.018
cellular response to molecule of bacterial origin GO:0071219 3 0.018
regulation of cell proliferation GO:0042127 163 0.018
regulation of neuron death GO:1901214 26 0.018
aromatic compound catabolic process GO:0019439 166 0.018
proton transport GO:0015992 7 0.018
cellular response to organic cyclic compound GO:0071407 32 0.018
generation of precursor metabolites and energy GO:0006091 42 0.017
regulation of defense response to bacterium GO:1900424 30 0.017
negative regulation of cell communication GO:0010648 223 0.017
purine ribonucleoside metabolic process GO:0046128 127 0.017
sensory perception of taste GO:0050909 25 0.017
positive regulation of innate immune response GO:0045089 38 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
ventral furrow formation GO:0007370 17 0.017
multi organism behavior GO:0051705 175 0.017
protein targeting GO:0006605 64 0.016
positive regulation of cellular amide metabolic process GO:0034250 26 0.016
jnk cascade GO:0007254 50 0.016
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
stem cell differentiation GO:0048863 117 0.016
mitotic chromosome condensation GO:0007076 22 0.016
cellular amide metabolic process GO:0043603 80 0.016
cytoplasmic transport GO:0016482 130 0.016
heterocycle catabolic process GO:0046700 166 0.016
camera type eye morphogenesis GO:0048593 2 0.016
stem cell maintenance GO:0019827 67 0.016
limb morphogenesis GO:0035108 1 0.016
peripheral nervous system development GO:0007422 52 0.016
tor signaling GO:0031929 32 0.016
organic cyclic compound catabolic process GO:1901361 168 0.016
antibacterial peptide biosynthetic process GO:0002780 22 0.016
mapk cascade GO:0000165 107 0.015
heterochromatin assembly GO:0031507 13 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
positive regulation of cellular component organization GO:0051130 156 0.015
detection of stimulus GO:0051606 156 0.015
protein complex assembly GO:0006461 200 0.015
negative regulation of apoptotic process GO:0043066 63 0.015
cellularization GO:0007349 90 0.015
pole cell formation GO:0007279 19 0.015
salivary gland cell autophagic cell death GO:0035071 83 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
endocytic recycling GO:0032456 13 0.015
cellular macromolecule localization GO:0070727 220 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
negative regulation of chromosome organization GO:2001251 19 0.015
translation GO:0006412 69 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
homeostatic process GO:0042592 199 0.015
protein maturation GO:0051604 71 0.014
positive regulation of multicellular organismal process GO:0051240 143 0.014
rhythmic process GO:0048511 106 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
regulation of protein modification process GO:0031399 112 0.014
regulation of programmed cell death GO:0043067 152 0.014
striated muscle cell differentiation GO:0051146 90 0.014
eggshell chorion assembly GO:0007306 66 0.014
regulation of cytoskeleton organization GO:0051493 89 0.014
necrotic cell death GO:0070265 1 0.014
regulation of establishment of protein localization GO:0070201 61 0.014
columnar cuboidal epithelial cell development GO:0002066 249 0.014
negative regulation of response to external stimulus GO:0032102 22 0.014
negative regulation of dna metabolic process GO:0051053 12 0.014
asymmetric stem cell division GO:0098722 49 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
negative regulation of chromosome segregation GO:0051985 14 0.014
organophosphate catabolic process GO:0046434 112 0.014
regulation of intracellular transport GO:0032386 64 0.014
positive regulation of immune system process GO:0002684 68 0.013
protein phosphorylation GO:0006468 169 0.013
regulation of cell differentiation GO:0045595 302 0.013
melanization defense response GO:0035006 45 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
positive regulation of jun kinase activity GO:0043507 4 0.013
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
determination of adult lifespan GO:0008340 137 0.013
positive regulation of tor signaling GO:0032008 13 0.013
meiotic cell cycle process GO:1903046 132 0.013
neuron death GO:0070997 27 0.013
hemolymph coagulation GO:0042381 10 0.013
appendage morphogenesis GO:0035107 397 0.013
sex differentiation GO:0007548 81 0.013
positive regulation of nf kappab import into nucleus GO:0042346 1 0.013
positive regulation of protein phosphorylation GO:0001934 34 0.013
transmembrane transport GO:0055085 139 0.012
positive regulation of apoptotic process GO:0043065 47 0.012
chaeta morphogenesis GO:0008407 42 0.012
establishment or maintenance of cell polarity GO:0007163 167 0.012
regulation of protein catabolic process GO:0042176 55 0.012
cell growth GO:0016049 108 0.012
response to nitrogen compound GO:1901698 90 0.012
stem cell development GO:0048864 79 0.012
digestive system development GO:0055123 149 0.012
response to oxygen levels GO:0070482 59 0.012
lipopolysaccharide mediated signaling pathway GO:0031663 1 0.012
positive regulation of cell death GO:0010942 69 0.012
cellular response to arsenic containing substance GO:0071243 6 0.012
ribonucleotide catabolic process GO:0009261 109 0.012
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
circadian rhythm GO:0007623 105 0.012
dna repair GO:0006281 54 0.012
cellular protein complex disassembly GO:0043624 35 0.012
meiotic sister chromatid segregation GO:0045144 6 0.012
rrna processing GO:0006364 3 0.011

AGO2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.050
disease of cellular proliferation DOID:14566 0 0.050
organ system cancer DOID:0050686 0 0.050