Drosophila melanogaster

65 known processes

CG40351 (Dmel_CG40351)

CG40351 gene product from transcript CG40351-RF

(Aliases: Dmel\CG40351,aaf45425 Dm,CG17395,CG17396)

CG40351 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage morphogenesis GO:0035107 397 0.141
negative regulation of gene expression GO:0010629 387 0.122
positive regulation of macromolecule metabolic process GO:0010604 405 0.091
negative regulation of rna metabolic process GO:0051253 251 0.082
protein modification process GO:0036211 438 0.080
chromosome organization GO:0051276 360 0.077
regulation of gene expression epigenetic GO:0040029 128 0.069
positive regulation of response to stimulus GO:0048584 323 0.069
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.066
post embryonic appendage morphogenesis GO:0035120 385 0.066
appendage development GO:0048736 401 0.065
positive regulation of cell communication GO:0010647 250 0.062
positive regulation of signaling GO:0023056 243 0.062
cellular protein modification process GO:0006464 438 0.061
chromatin organization GO:0006325 207 0.060
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.060
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.059
chromatin modification GO:0016568 147 0.058
negative regulation of cellular metabolic process GO:0031324 382 0.056
imaginal disc derived appendage morphogenesis GO:0035114 395 0.054
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.052
negative regulation of signal transduction GO:0009968 206 0.052
organic acid metabolic process GO:0006082 103 0.051
imaginal disc derived wing morphogenesis GO:0007476 337 0.050
negative regulation of nucleic acid templated transcription GO:1903507 240 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.049
negative regulation of transcription dna templated GO:0045892 237 0.048
wing disc morphogenesis GO:0007472 344 0.048
posttranscriptional gene silencing GO:0016441 46 0.048
negative regulation of biosynthetic process GO:0009890 277 0.047
positive regulation of cellular biosynthetic process GO:0031328 316 0.046
organelle fission GO:0048285 340 0.046
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.045
negative regulation of signaling GO:0023057 219 0.043
organonitrogen compound metabolic process GO:1901564 318 0.043
organic substance catabolic process GO:1901575 308 0.042
negative regulation of rna biosynthetic process GO:1902679 240 0.040
intracellular signal transduction GO:0035556 300 0.039
cell motility GO:0048870 251 0.039
heterocycle catabolic process GO:0046700 166 0.039
transcription from rna polymerase ii promoter GO:0006366 368 0.038
cellular amino acid metabolic process GO:0006520 61 0.038
negative regulation of response to stimulus GO:0048585 258 0.038
localization of cell GO:0051674 257 0.038
imaginal disc derived appendage development GO:0048737 399 0.037
chromatin silencing GO:0006342 76 0.036
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.036
positive regulation of nucleic acid templated transcription GO:1903508 266 0.036
positive regulation of transcription dna templated GO:0045893 266 0.036
cell adhesion GO:0007155 136 0.035
negative regulation of cell cycle process GO:0010948 109 0.034
carboxylic acid metabolic process GO:0019752 92 0.034
negative regulation of cellular biosynthetic process GO:0031327 277 0.033
positive regulation of signal transduction GO:0009967 223 0.033
salivary gland morphogenesis GO:0007435 145 0.033
oxoacid metabolic process GO:0043436 103 0.033
small molecule metabolic process GO:0044281 305 0.033
negative regulation of gene expression epigenetic GO:0045814 77 0.032
mitotic spindle organization GO:0007052 220 0.031
protein complex biogenesis GO:0070271 201 0.031
protein localization GO:0008104 284 0.031
lateral inhibition GO:0046331 206 0.031
salivary gland development GO:0007431 162 0.031
homeostatic process GO:0042592 199 0.031
positive regulation of rna metabolic process GO:0051254 271 0.030
negative regulation of cell communication GO:0010648 223 0.030
positive regulation of gene expression GO:0010628 290 0.029
phosphorylation GO:0016310 294 0.029
catabolic process GO:0009056 409 0.029
body morphogenesis GO:0010171 2 0.029
purine ribonucleoside catabolic process GO:0046130 112 0.029
cell cell signaling involved in cell fate commitment GO:0045168 210 0.029
exocrine system development GO:0035272 162 0.028
establishment of localization in cell GO:0051649 402 0.028
dna metabolic process GO:0006259 227 0.028
phagocytosis GO:0006909 215 0.027
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.027
gene silencing GO:0016458 138 0.027
regulation of cellular amino acid metabolic process GO:0006521 0 0.026
cellular response to abiotic stimulus GO:0071214 58 0.026
covalent chromatin modification GO:0016569 106 0.026
purine ribonucleoside metabolic process GO:0046128 127 0.026
regulation of organelle organization GO:0033043 196 0.026
response to other organism GO:0051707 293 0.026
nuclear division GO:0000280 332 0.026
cell death GO:0008219 279 0.025
response to abiotic stimulus GO:0009628 341 0.025
negative regulation of cell cycle GO:0045786 116 0.025
cellular catabolic process GO:0044248 372 0.025
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.025
death GO:0016265 284 0.025
regulation of localization GO:0032879 275 0.024
epithelial cell migration GO:0010631 148 0.024
macromolecular complex assembly GO:0065003 256 0.024
actin filament based process GO:0030029 220 0.024
regulation of cellular amine metabolic process GO:0033238 3 0.024
protein modification by small protein conjugation or removal GO:0070647 106 0.024
vesicle mediated transport GO:0016192 381 0.024
nucleobase containing compound catabolic process GO:0034655 165 0.023
programmed cell death GO:0012501 257 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.023
posttranscriptional gene silencing by rna GO:0035194 45 0.023
gland development GO:0048732 191 0.023
purine containing compound metabolic process GO:0072521 155 0.023
cellular amine metabolic process GO:0044106 12 0.022
compound eye development GO:0048749 307 0.022
regionalization GO:0003002 416 0.022
cell migration GO:0016477 238 0.022
regulation of anatomical structure size GO:0090066 163 0.022
cellular macromolecule localization GO:0070727 220 0.022
endocytosis GO:0006897 310 0.022
sensory organ morphogenesis GO:0090596 260 0.022
defense response GO:0006952 300 0.022
small gtpase mediated signal transduction GO:0007264 88 0.021
response to organic substance GO:0010033 284 0.021
cellular response to dna damage stimulus GO:0006974 223 0.021
regulation of response to stress GO:0080134 200 0.021
cellular ketone metabolic process GO:0042180 24 0.021
positive regulation of biosynthetic process GO:0009891 316 0.020
histone modification GO:0016570 106 0.020
regulation of catalytic activity GO:0050790 185 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
organonitrogen compound catabolic process GO:1901565 128 0.020
chromatin assembly or disassembly GO:0006333 52 0.020
open tracheal system development GO:0007424 204 0.020
positive regulation of rna biosynthetic process GO:1902680 266 0.020
mitotic sister chromatid segregation GO:0000070 87 0.020
biological adhesion GO:0022610 138 0.020
single organism catabolic process GO:0044712 228 0.020
aromatic compound catabolic process GO:0019439 166 0.019
chromosome segregation GO:0007059 157 0.019
nuclear transport GO:0051169 72 0.019
regulation of cellular component biogenesis GO:0044087 201 0.019
positive regulation of phosphorus metabolic process GO:0010562 139 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
muscle structure development GO:0061061 224 0.019
gtp catabolic process GO:0006184 72 0.019
signal transduction by phosphorylation GO:0023014 107 0.019
salivary gland histolysis GO:0035070 88 0.019
mrna metabolic process GO:0016071 124 0.019
response to biotic stimulus GO:0009607 294 0.019
cellular nitrogen compound catabolic process GO:0044270 165 0.019
ras protein signal transduction GO:0007265 88 0.019
single organism intracellular transport GO:1902582 207 0.019
purine containing compound catabolic process GO:0072523 112 0.018
telencephalon development GO:0021537 2 0.018
protein phosphorylation GO:0006468 169 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
organic substance transport GO:0071702 257 0.018
camera type eye development GO:0043010 4 0.018
gland morphogenesis GO:0022612 145 0.018
axon development GO:0061564 297 0.018
embryo development ending in birth or egg hatching GO:0009792 152 0.018
epithelial cell differentiation GO:0030855 322 0.018
positive regulation of cellular amine metabolic process GO:0033240 0 0.018
regulation of transport GO:0051049 181 0.018
cytoplasmic transport GO:0016482 130 0.018
nucleotide metabolic process GO:0009117 161 0.018
developmental programmed cell death GO:0010623 138 0.018
g protein coupled receptor signaling pathway GO:0007186 136 0.018
response to external biotic stimulus GO:0043207 293 0.017
cellular macromolecule catabolic process GO:0044265 136 0.017
protein complex assembly GO:0006461 200 0.017
sterol homeostasis GO:0055092 4 0.017
oocyte differentiation GO:0009994 145 0.017
regulation of epithelial cell proliferation GO:0050678 4 0.017
spermatogenesis GO:0007283 200 0.017
tissue death GO:0016271 102 0.017
rna processing GO:0006396 147 0.017
nucleotide catabolic process GO:0009166 109 0.017
cellular homeostasis GO:0019725 80 0.017
proteolysis GO:0006508 192 0.016
negative regulation of cellular protein metabolic process GO:0032269 85 0.016
chemical homeostasis GO:0048878 92 0.016
purine nucleoside catabolic process GO:0006152 112 0.016
erbb signaling pathway GO:0038127 58 0.016
spindle organization GO:0007051 253 0.016
neuron recognition GO:0008038 101 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
nucleoside metabolic process GO:0009116 127 0.016
inorganic ion transmembrane transport GO:0098660 73 0.016
cellular macromolecular complex assembly GO:0034622 153 0.016
spindle elongation GO:0051231 83 0.016
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.016
macromolecule catabolic process GO:0009057 161 0.016
growth GO:0040007 359 0.016
ribonucleotide metabolic process GO:0009259 145 0.016
apoptotic process GO:0006915 159 0.016
regulation of gene silencing GO:0060968 63 0.016
forebrain development GO:0030900 2 0.016
regulation of intracellular signal transduction GO:1902531 236 0.015
ribose phosphate metabolic process GO:0019693 145 0.015
regulation of molecular function GO:0065009 217 0.015
cell cycle checkpoint GO:0000075 95 0.015
amine metabolic process GO:0009308 12 0.015
cell proliferation GO:0008283 299 0.015
ion transport GO:0006811 145 0.015
neuron projection guidance GO:0097485 241 0.015
ameboidal type cell migration GO:0001667 151 0.015
positive regulation of catalytic activity GO:0043085 118 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.015
protein deubiquitination GO:0016579 17 0.015
single organism behavior GO:0044708 391 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
regulation of ras protein signal transduction GO:0046578 93 0.015
purine nucleoside triphosphate catabolic process GO:0009146 108 0.015
digestive tract development GO:0048565 149 0.015
carbohydrate derivative metabolic process GO:1901135 217 0.015
organophosphate metabolic process GO:0019637 195 0.015
respiratory system development GO:0060541 213 0.015
glycosyl compound catabolic process GO:1901658 112 0.014
guanosine containing compound metabolic process GO:1901068 74 0.014
digestive tract morphogenesis GO:0048546 127 0.014
male gamete generation GO:0048232 201 0.014
notch signaling pathway GO:0007219 120 0.014
water homeostasis GO:0030104 3 0.014
hindbrain development GO:0030902 2 0.014
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.014
regulation of synapse structure and activity GO:0050803 128 0.014
lipid storage GO:0019915 38 0.014
regulation of small gtpase mediated signal transduction GO:0051056 93 0.014
defense response to bacterium GO:0042742 178 0.014
cellular protein localization GO:0034613 160 0.014
ribonucleoside triphosphate catabolic process GO:0009203 108 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
antimicrobial humoral response GO:0019730 99 0.014
digestive system development GO:0055123 149 0.014
guanosine containing compound catabolic process GO:1901069 74 0.014
regulation of chromosome organization GO:0033044 64 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
regulation of nervous system development GO:0051960 248 0.014
regulation of immune response GO:0050776 118 0.014
compound eye morphogenesis GO:0001745 249 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
salivary gland cell autophagic cell death GO:0035071 83 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
mrna processing GO:0006397 104 0.013
protein maturation GO:0051604 71 0.013
chromatin remodeling GO:0006338 72 0.013
regulation of erbb signaling pathway GO:1901184 42 0.013
dna packaging GO:0006323 91 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
positive regulation of molecular function GO:0044093 136 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
cellular response to radiation GO:0071478 52 0.013
organophosphate catabolic process GO:0046434 112 0.013
histolysis GO:0007559 102 0.013
cholesterol transport GO:0030301 2 0.013
synaptic transmission GO:0007268 288 0.013
dendrite morphogenesis GO:0048813 199 0.013
defense response to other organism GO:0098542 225 0.013
protein modification by small protein removal GO:0070646 28 0.013
regulation of cellular component size GO:0032535 98 0.013
cellular response to nutrient levels GO:0031669 62 0.013
response to lipopolysaccharide GO:0032496 4 0.013
imaginal disc pattern formation GO:0007447 91 0.013
negative regulation of epithelial cell proliferation GO:0050680 4 0.013
immune response activating signal transduction GO:0002757 2 0.013
organelle membrane fusion GO:0090174 16 0.013
regulation of phosphorylation GO:0042325 147 0.013
mapk cascade GO:0000165 107 0.013
ribosomal large subunit biogenesis GO:0042273 1 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.012
single organism biosynthetic process GO:0044711 206 0.012
nucleoside catabolic process GO:0009164 112 0.012
multi organism behavior GO:0051705 175 0.012
eye development GO:0001654 323 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
regulation of establishment of protein localization GO:0070201 61 0.012
regulation of hydrolase activity GO:0051336 97 0.012
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.012
proteasomal protein catabolic process GO:0010498 59 0.012
regulation of mapk cascade GO:0043408 92 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
regulation of mitotic cell cycle phase transition GO:1901990 130 0.012
protein catabolic process GO:0030163 101 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
humoral immune response GO:0006959 117 0.012
synapse assembly GO:0007416 143 0.012
taxis GO:0042330 304 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
negative regulation of erbb signaling pathway GO:1901185 29 0.012
negative regulation of cellular component organization GO:0051129 108 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
intracellular protein transport GO:0006886 104 0.012
positive regulation of cell motility GO:2000147 3 0.012
regulation of intracellular transport GO:0032386 64 0.012
regulation of cell cycle process GO:0010564 181 0.012
epithelium migration GO:0090132 148 0.012
maintenance of location GO:0051235 73 0.012
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.012
regulation of proteolysis GO:0030162 87 0.012
axonogenesis GO:0007409 290 0.012
somatic muscle development GO:0007525 66 0.012
carbohydrate metabolic process GO:0005975 82 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
immune response GO:0006955 246 0.011
protein transport GO:0015031 155 0.011
response to glucose GO:0009749 2 0.011
drinking behavior GO:0042756 2 0.011
epidermal growth factor receptor signaling pathway GO:0007173 58 0.011
cellular response to starvation GO:0009267 61 0.011
response to oxygen containing compound GO:1901700 200 0.011
rna 3 end processing GO:0031123 45 0.011
immune response regulating signaling pathway GO:0002764 2 0.011
response to monosaccharide GO:0034284 4 0.011
imaginal disc derived wing vein specification GO:0007474 48 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
wing disc pattern formation GO:0035222 66 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
sister chromatid segregation GO:0000819 92 0.011
cholesterol homeostasis GO:0042632 3 0.011
eye morphogenesis GO:0048592 260 0.011
ovarian follicle cell development GO:0030707 248 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
autophagic cell death GO:0048102 83 0.011
positive regulation of ras gtpase activity GO:0032320 36 0.011
rhythmic process GO:0048511 106 0.011
nucleoside phosphate metabolic process GO:0006753 162 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
mitotic cell cycle phase transition GO:0044772 138 0.011
regulation of cell size GO:0008361 63 0.011
protein ubiquitination GO:0016567 70 0.011
cellular response to external stimulus GO:0071496 66 0.011
cell recognition GO:0008037 102 0.011
purine nucleoside triphosphate metabolic process GO:0009144 119 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
protein processing GO:0016485 68 0.011
kidney development GO:0001822 3 0.010
rrna processing GO:0006364 3 0.010
rna splicing via transesterification reactions GO:0000375 73 0.010
mitotic nuclear division GO:0007067 213 0.010
limb development GO:0060173 1 0.010
regulation of cell projection organization GO:0031344 92 0.010
regulation of immune system process GO:0002682 176 0.010
response to radiation GO:0009314 155 0.010
protein localization to organelle GO:0033365 82 0.010
peptidyl threonine modification GO:0018210 3 0.010
purine nucleotide catabolic process GO:0006195 109 0.010
purine nucleoside metabolic process GO:0042278 127 0.010
stem cell differentiation GO:0048863 117 0.010
response to light stimulus GO:0009416 124 0.010
innate immune response GO:0045087 144 0.010

CG40351 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.046
disease of metabolism DOID:0014667 0 0.020
diabetes mellitus DOID:9351 0 0.017
type 2 diabetes mellitus DOID:9352 0 0.017
carbohydrate metabolism disease DOID:0050013 0 0.017
glucose metabolism disease DOID:4194 0 0.017
acquired metabolic disease DOID:0060158 0 0.017
sensory system disease DOID:0050155 0 0.015
nervous system disease DOID:863 0 0.015
inherited metabolic disorder DOID:655 0 0.013
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
eye and adnexa disease DOID:1492 0 0.013
eye disease DOID:5614 0 0.013
organ system cancer DOID:0050686 0 0.012
musculoskeletal system disease DOID:17 0 0.011