Drosophila melanogaster

42 known processes

Lig4 (Dmel_CG12176)

Ligase4

(Aliases: lig4,RE37186,CG12176,Dmel\CG12176)

Lig4 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 227 0.723
dna repair GO:0006281 54 0.480
telomere organization GO:0032200 21 0.394
chromosome organization GO:0051276 360 0.268
double strand break repair via nonhomologous end joining GO:0006303 5 0.224
cellular catabolic process GO:0044248 372 0.201
purine nucleotide metabolic process GO:0006163 146 0.161
nucleobase containing compound catabolic process GO:0034655 165 0.160
nucleoside triphosphate metabolic process GO:0009141 120 0.151
double strand break repair GO:0006302 26 0.148
carbohydrate derivative metabolic process GO:1901135 217 0.133
catabolic process GO:0009056 409 0.126
purine nucleoside triphosphate metabolic process GO:0009144 119 0.124
response to abiotic stimulus GO:0009628 341 0.124
ribonucleoside triphosphate catabolic process GO:0009203 108 0.114
organophosphate metabolic process GO:0019637 195 0.109
heterocycle catabolic process GO:0046700 166 0.107
regionalization GO:0003002 416 0.097
ribonucleoside triphosphate metabolic process GO:0009199 119 0.095
nucleoside catabolic process GO:0009164 112 0.093
organic cyclic compound catabolic process GO:1901361 168 0.092
ribonucleotide metabolic process GO:0009259 145 0.091
purine containing compound metabolic process GO:0072521 155 0.091
purine nucleoside catabolic process GO:0006152 112 0.091
cellular response to dna damage stimulus GO:0006974 223 0.091
nucleoside monophosphate metabolic process GO:0009123 52 0.090
chromatin organization GO:0006325 207 0.089
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.083
negative regulation of cellular metabolic process GO:0031324 382 0.082
ribonucleoside catabolic process GO:0042454 112 0.081
glycosyl compound metabolic process GO:1901657 127 0.081
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.079
organonitrogen compound metabolic process GO:1901564 318 0.078
response to radiation GO:0009314 155 0.076
aromatic compound catabolic process GO:0019439 166 0.075
purine nucleoside monophosphate metabolic process GO:0009126 50 0.074
nucleobase containing small molecule metabolic process GO:0055086 174 0.073
nucleoside phosphate metabolic process GO:0006753 162 0.073
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.073
organic substance catabolic process GO:1901575 308 0.072
purine ribonucleoside metabolic process GO:0046128 127 0.072
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.071
nucleoside metabolic process GO:0009116 127 0.071
purine ribonucleotide metabolic process GO:0009150 145 0.070
ribonucleoside metabolic process GO:0009119 127 0.069
purine nucleotide catabolic process GO:0006195 109 0.068
purine ribonucleotide catabolic process GO:0009154 109 0.068
purine ribonucleoside catabolic process GO:0046130 112 0.066
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.066
carbohydrate derivative catabolic process GO:1901136 118 0.065
ribonucleotide catabolic process GO:0009261 109 0.064
purine containing compound catabolic process GO:0072523 112 0.062
purine nucleoside triphosphate catabolic process GO:0009146 108 0.061
cellular nitrogen compound catabolic process GO:0044270 165 0.060
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.059
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.058
nucleotide catabolic process GO:0009166 109 0.058
nucleoside triphosphate catabolic process GO:0009143 108 0.058
atp metabolic process GO:0046034 49 0.057
small molecule metabolic process GO:0044281 305 0.053
ribose phosphate metabolic process GO:0019693 145 0.051
anterior posterior pattern specification GO:0009952 136 0.050
vesicle mediated transport GO:0016192 381 0.048
mitotic g2 m transition checkpoint GO:0044818 70 0.047
purine nucleoside metabolic process GO:0042278 127 0.047
organophosphate catabolic process GO:0046434 112 0.046
nucleoside phosphate catabolic process GO:1901292 110 0.045
organonitrogen compound catabolic process GO:1901565 128 0.045
cellular component assembly involved in morphogenesis GO:0010927 151 0.045
cellular macromolecule localization GO:0070727 220 0.044
single organism biosynthetic process GO:0044711 206 0.044
ribonucleoside monophosphate metabolic process GO:0009161 51 0.040
telomere maintenance GO:0000723 21 0.039
cellular response to radiation GO:0071478 52 0.039
small gtpase mediated signal transduction GO:0007264 88 0.039
negative regulation of gene expression GO:0010629 387 0.039
negative regulation of cellular biosynthetic process GO:0031327 277 0.038
anatomical structure homeostasis GO:0060249 97 0.038
immune system process GO:0002376 347 0.036
endocytosis GO:0006897 310 0.035
regulation of intracellular signal transduction GO:1902531 236 0.035
nucleotide metabolic process GO:0009117 161 0.034
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.033
regulation of response to stress GO:0080134 200 0.033
chromatin remodeling GO:0006338 72 0.033
intracellular transport GO:0046907 228 0.032
ribonucleoside monophosphate catabolic process GO:0009158 39 0.032
cellular protein modification process GO:0006464 438 0.032
negative regulation of biosynthetic process GO:0009890 277 0.031
signal transduction by phosphorylation GO:0023014 107 0.030
purine nucleoside monophosphate catabolic process GO:0009128 38 0.030
atp catabolic process GO:0006200 38 0.029
nuclear division GO:0000280 332 0.029
ras protein signal transduction GO:0007265 88 0.028
regulation of ras protein signal transduction GO:0046578 93 0.028
anterior posterior axis specification GO:0009948 109 0.027
female meiotic division GO:0007143 70 0.027
axis specification GO:0009798 167 0.027
intracellular mrna localization GO:0008298 66 0.027
dna biosynthetic process GO:0071897 24 0.026
protein localization GO:0008104 284 0.026
regulation of phosphate metabolic process GO:0019220 210 0.026
male gamete generation GO:0048232 201 0.026
positive regulation of phosphorus metabolic process GO:0010562 139 0.025
immune response GO:0006955 246 0.025
chromosome segregation GO:0007059 157 0.025
organelle fission GO:0048285 340 0.024
response to ionizing radiation GO:0010212 32 0.024
intracellular signal transduction GO:0035556 300 0.024
macromolecular complex assembly GO:0065003 256 0.023
response to light stimulus GO:0009416 124 0.023
regulation of mitotic cell cycle GO:0007346 190 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
positive regulation of multicellular organismal process GO:0051240 143 0.023
gene silencing GO:0016458 138 0.022
defense response to other organism GO:0098542 225 0.022
regulation of cellular ketone metabolic process GO:0010565 3 0.022
regulation of localization GO:0032879 275 0.022
protein complex assembly GO:0006461 200 0.022
macromolecule catabolic process GO:0009057 161 0.022
regulation of molecular function GO:0065009 217 0.021
cellular protein localization GO:0034613 160 0.021
non recombinational repair GO:0000726 7 0.021
protein modification process GO:0036211 438 0.021
cellular macromolecule catabolic process GO:0044265 136 0.021
meiotic nuclear division GO:0007126 151 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
regulation of small gtpase mediated signal transduction GO:0051056 93 0.021
developmental maturation GO:0021700 172 0.020
proteolysis GO:0006508 192 0.020
blastoderm segmentation GO:0007350 159 0.020
dorsal ventral pattern formation GO:0009953 133 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
glycosyl compound catabolic process GO:1901658 112 0.020
regulation of gene expression epigenetic GO:0040029 128 0.019
immune system development GO:0002520 57 0.019
postreplication repair GO:0006301 2 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.019
cell cycle phase transition GO:0044770 140 0.019
oocyte differentiation GO:0009994 145 0.019
single organism catabolic process GO:0044712 228 0.019
positive regulation of molecular function GO:0044093 136 0.019
protein complex biogenesis GO:0070271 201 0.019
imaginal disc derived wing morphogenesis GO:0007476 337 0.019
cellular response to ionizing radiation GO:0071479 15 0.018
response to other organism GO:0051707 293 0.018
positive regulation of macromolecule metabolic process GO:0010604 405 0.018
negative regulation of nucleic acid templated transcription GO:1903507 240 0.018
defense response GO:0006952 300 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
forebrain development GO:0030900 2 0.018
positive regulation of apoptotic signaling pathway GO:2001235 4 0.018
nucleoside monophosphate catabolic process GO:0009125 39 0.018
response to bacterium GO:0009617 198 0.018
positive regulation of nucleotide catabolic process GO:0030813 46 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
regulation of hydrolase activity GO:0051336 97 0.017
response to organic substance GO:0010033 284 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
spermatogenesis GO:0007283 200 0.017
chromatin assembly or disassembly GO:0006333 52 0.017
appendage development GO:0048736 401 0.017
single organism cellular localization GO:1902580 180 0.017
chromatin modification GO:0016568 147 0.017
single organism intracellular transport GO:1902582 207 0.017
death GO:0016265 284 0.016
positive regulation of rna biosynthetic process GO:1902680 266 0.016
cytoplasmic transport GO:0016482 130 0.016
compound eye development GO:0048749 307 0.016
translesion synthesis GO:0019985 2 0.016
tripartite regional subdivision GO:0007351 103 0.016
meiotic cell cycle GO:0051321 171 0.016
amine metabolic process GO:0009308 12 0.016
epithelial cell differentiation GO:0030855 322 0.016
tissue migration GO:0090130 155 0.016
regulation of synapse structure and activity GO:0050803 128 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
multi organism behavior GO:0051705 175 0.016
negative regulation of transcription dna templated GO:0045892 237 0.015
segmentation GO:0035282 207 0.015
g2 dna damage checkpoint GO:0031572 69 0.015
chromatin silencing GO:0006342 76 0.015
cellular response to abiotic stimulus GO:0071214 58 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
metal ion transport GO:0030001 74 0.015
regulation of catalytic activity GO:0050790 185 0.015
homeostatic process GO:0042592 199 0.015
mitotic dna integrity checkpoint GO:0044774 75 0.015
protein transport GO:0015031 155 0.014
protein processing GO:0016485 68 0.014
protein catabolic process GO:0030163 101 0.014
neurological system process GO:0050877 358 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
taxis GO:0042330 304 0.014
response to external biotic stimulus GO:0043207 293 0.014
positive regulation of ras gtpase activity GO:0032320 36 0.014
regulation of catabolic process GO:0009894 170 0.014
ameboidal type cell migration GO:0001667 151 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
regulation of transport GO:0051049 181 0.014
meiotic cell cycle process GO:1903046 132 0.014
positive regulation of biosynthetic process GO:0009891 316 0.013
innate immune response GO:0045087 144 0.013
axonogenesis GO:0007409 290 0.013
positive regulation of cell migration GO:0030335 2 0.013
immune effector process GO:0002252 98 0.013
axon development GO:0061564 297 0.013
regulation of phosphorus metabolic process GO:0051174 210 0.013
maternal determination of anterior posterior axis embryo GO:0008358 74 0.013
response to lipopolysaccharide GO:0032496 4 0.013
hemopoiesis GO:0030097 46 0.013
mitotic g2 dna damage checkpoint GO:0007095 69 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
protein modification by small protein conjugation GO:0032446 79 0.013
cell cycle checkpoint GO:0000075 95 0.013
regulation of cell differentiation GO:0045595 302 0.013
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.013
establishment of protein localization GO:0045184 163 0.013
telencephalon development GO:0021537 2 0.013
wing disc morphogenesis GO:0007472 344 0.012
positive regulation of cellular amine metabolic process GO:0033240 0 0.012
regulation of nervous system development GO:0051960 248 0.012
response to oxygen containing compound GO:1901700 200 0.012
rna localization GO:0006403 115 0.012
regulation of cellular localization GO:0060341 136 0.012
cellular homeostasis GO:0019725 80 0.012
regulation of cell cycle GO:0051726 291 0.012
cell motility GO:0048870 251 0.012
dna damage checkpoint GO:0000077 78 0.012
regulation of dna recombination GO:0000018 4 0.012
lateral inhibition GO:0046331 206 0.012
regulation of response to external stimulus GO:0032101 115 0.012
positive regulation of developmental process GO:0051094 143 0.012
phagocytosis GO:0006909 215 0.012
eye development GO:0001654 323 0.012
regulation of chromosome organization GO:0033044 64 0.012
ocellus pigment metabolic process GO:0046158 19 0.012
embryonic axis specification GO:0000578 107 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
regulation of cellular response to stress GO:0080135 89 0.011
positive regulation of signaling GO:0023056 243 0.011
positive regulation of transport GO:0051050 92 0.011
histone modification GO:0016570 106 0.011
cellular protein complex assembly GO:0043623 71 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
appendage morphogenesis GO:0035107 397 0.011
protein dna complex subunit organization GO:0071824 86 0.011
positive regulation of catabolic process GO:0009896 105 0.011
positive regulation of catalytic activity GO:0043085 118 0.011
epithelial cell development GO:0002064 274 0.011
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.011
negative regulation of cell death GO:0060548 81 0.011
regulation of response to dna damage stimulus GO:2001020 23 0.011
dna integrity checkpoint GO:0031570 81 0.011
locomotory behavior GO:0007626 176 0.011
positive regulation of signal transduction GO:0009967 223 0.011
germarium derived egg chamber formation GO:0007293 101 0.011
regulation of ras gtpase activity GO:0032318 38 0.011
positive regulation of phosphate metabolic process GO:0045937 139 0.011
axon guidance GO:0007411 233 0.011
regulation of cellular protein metabolic process GO:0032268 243 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
body morphogenesis GO:0010171 2 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
signal transduction in response to dna damage GO:0042770 3 0.011
ovarian follicle cell development GO:0030707 248 0.011
pigment metabolic process involved in developmental pigmentation GO:0043324 33 0.011
positive regulation of cell motility GO:2000147 3 0.011
positive regulation of gene expression GO:0010628 290 0.011
reproductive system development GO:0061458 74 0.010
mapk cascade GO:0000165 107 0.010
regulation of nucleotide metabolic process GO:0006140 62 0.010
cellular amine metabolic process GO:0044106 12 0.010
negative regulation of rna metabolic process GO:0051253 251 0.010
regulation of gtp catabolic process GO:0033124 44 0.010
regulation of phosphorylation GO:0042325 147 0.010
regulation of nucleoside metabolic process GO:0009118 50 0.010
protein localization to organelle GO:0033365 82 0.010
phosphorylation GO:0016310 294 0.010
developmental growth GO:0048589 280 0.010
meiosis i GO:0007127 59 0.010

Lig4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018
disease of cellular proliferation DOID:14566 0 0.017
sensory system disease DOID:0050155 0 0.015
nervous system disease DOID:863 0 0.015
cancer DOID:162 0 0.013