Drosophila melanogaster

0 known processes

Nhe1 (Dmel_CG12178)

Na[+]/H[+] hydrogen exchanger 1

(Aliases: nhe1,CG12178,Dmel\CG12178,NHE1,DmNHE1)

Nhe1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
establishment of localization in cell GO:0051649 402 0.073
organonitrogen compound metabolic process GO:1901564 318 0.061
detection of stimulus GO:0051606 156 0.058
catabolic process GO:0009056 409 0.056
small molecule metabolic process GO:0044281 305 0.041
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.039
single organism intracellular transport GO:1902582 207 0.037
regulation of transport GO:0051049 181 0.036
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.035
cellular component assembly involved in morphogenesis GO:0010927 151 0.033
protein modification process GO:0036211 438 0.031
positive regulation of biosynthetic process GO:0009891 316 0.031
neurological system process GO:0050877 358 0.031
organic substance catabolic process GO:1901575 308 0.030
cellular catabolic process GO:0044248 372 0.030
response to organic substance GO:0010033 284 0.030
regulation of localization GO:0032879 275 0.030
positive regulation of signaling GO:0023056 243 0.030
protein localization GO:0008104 284 0.030
synaptic transmission GO:0007268 288 0.029
single organism catabolic process GO:0044712 228 0.029
organelle assembly GO:0070925 198 0.029
oxoacid metabolic process GO:0043436 103 0.029
carbohydrate derivative metabolic process GO:1901135 217 0.028
single organism membrane fusion GO:0044801 42 0.028
organic substance transport GO:0071702 257 0.027
positive regulation of cell communication GO:0010647 250 0.027
response to abiotic stimulus GO:0009628 341 0.027
male gamete generation GO:0048232 201 0.026
single organism biosynthetic process GO:0044711 206 0.026
skin development GO:0043588 65 0.026
response to nutrient levels GO:0031667 114 0.025
positive regulation of cellular biosynthetic process GO:0031328 316 0.025
respiratory system development GO:0060541 213 0.025
homeostatic process GO:0042592 199 0.025
Mouse
endomembrane system organization GO:0010256 119 0.025
response to starvation GO:0042594 97 0.024
nucleobase containing small molecule metabolic process GO:0055086 174 0.024
regulation of molecular function GO:0065009 217 0.024
regulation of catalytic activity GO:0050790 185 0.024
limb development GO:0060173 1 0.023
regionalization GO:0003002 416 0.023
forebrain development GO:0030900 2 0.023
chromosome organization GO:0051276 360 0.023
response to extracellular stimulus GO:0009991 116 0.023
metal ion transport GO:0030001 74 0.022
Mouse
organophosphate metabolic process GO:0019637 195 0.022
regulation of phosphorus metabolic process GO:0051174 210 0.022
nucleoside phosphate metabolic process GO:0006753 162 0.022
proteolysis GO:0006508 192 0.022
nucleobase containing compound catabolic process GO:0034655 165 0.022
intracellular transport GO:0046907 228 0.022
cellular protein modification process GO:0006464 438 0.022
vesicle mediated transport GO:0016192 381 0.022
epithelial cell differentiation GO:0030855 322 0.022
epithelial cell development GO:0002064 274 0.021
organelle fusion GO:0048284 46 0.021
membrane fusion GO:0061025 42 0.021
positive regulation of catalytic activity GO:0043085 118 0.021
regulation of cellular component biogenesis GO:0044087 201 0.021
cilium assembly GO:0042384 38 0.021
appendage development GO:0048736 401 0.021
organic acid metabolic process GO:0006082 103 0.021
spindle organization GO:0007051 253 0.021
cell proliferation GO:0008283 299 0.021
central nervous system development GO:0007417 201 0.020
single organism membrane organization GO:0044802 93 0.020
golgi organization GO:0007030 66 0.020
small gtpase mediated signal transduction GO:0007264 88 0.020
organophosphate catabolic process GO:0046434 112 0.020
connective tissue development GO:0061448 3 0.020
cellular amino acid metabolic process GO:0006520 61 0.020
kidney development GO:0001822 3 0.019
limb morphogenesis GO:0035108 1 0.019
ovarian follicle cell development GO:0030707 248 0.019
single organism behavior GO:0044708 391 0.019
ion transport GO:0006811 145 0.018
Mouse
positive regulation of signal transduction GO:0009967 223 0.018
endocytosis GO:0006897 310 0.018
aromatic compound catabolic process GO:0019439 166 0.018
positive regulation of response to stimulus GO:0048584 323 0.018
appendage morphogenesis GO:0035107 397 0.018
secretion GO:0046903 109 0.018
protein complex biogenesis GO:0070271 201 0.018
regulation of cell development GO:0060284 215 0.018
protein transport GO:0015031 155 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
carbohydrate derivative biosynthetic process GO:1901137 85 0.018
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
purine containing compound metabolic process GO:0072521 155 0.017
locomotory behavior GO:0007626 176 0.017
cellular nitrogen compound catabolic process GO:0044270 165 0.017
positive regulation of transport GO:0051050 92 0.017
regulation of cell differentiation GO:0045595 302 0.017
positive regulation of phosphorus metabolic process GO:0010562 139 0.017
cellularization GO:0007349 90 0.017
regulation of cellular localization GO:0060341 136 0.017
single organism carbohydrate metabolic process GO:0044723 72 0.017
heterocycle catabolic process GO:0046700 166 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
cellular response to organic substance GO:0071310 132 0.017
telencephalon development GO:0021537 2 0.016
ras protein signal transduction GO:0007265 88 0.016
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.016
cell motility GO:0048870 251 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
nucleoside phosphate catabolic process GO:1901292 110 0.016
endosomal transport GO:0016197 44 0.016
regulation of multicellular organismal development GO:2000026 414 0.016
memory GO:0007613 94 0.016
carbohydrate metabolic process GO:0005975 82 0.016
adult behavior GO:0030534 137 0.016
tube morphogenesis GO:0035239 191 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
embryonic morphogenesis GO:0048598 206 0.016
regulation of nervous system development GO:0051960 248 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
organelle fission GO:0048285 340 0.016
developmental maturation GO:0021700 172 0.016
response to biotic stimulus GO:0009607 294 0.016
cellular response to chemical stimulus GO:0070887 199 0.016
response to glucose GO:0009749 2 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.015
regulation of epithelial cell proliferation GO:0050678 4 0.015
regulation of phosphate metabolic process GO:0019220 210 0.015
response to endoplasmic reticulum stress GO:0034976 28 0.015
carbohydrate derivative catabolic process GO:1901136 118 0.015
steroid catabolic process GO:0006706 1 0.015
secretion by cell GO:0032940 101 0.015
organonitrogen compound catabolic process GO:1901565 128 0.015
cell projection assembly GO:0030031 94 0.015
intracellular signal transduction GO:0035556 300 0.015
spermatogenesis GO:0007283 200 0.015
response to oxygen containing compound GO:1901700 200 0.015
detection of chemical stimulus GO:0009593 93 0.015
phagocytosis GO:0006909 215 0.015
ribonucleoside catabolic process GO:0042454 112 0.015
cellular response to dna damage stimulus GO:0006974 223 0.015
peptide metabolic process GO:0006518 80 0.015
defense response to other organism GO:0098542 225 0.015
segmentation GO:0035282 207 0.015
dorsal ventral pattern formation GO:0009953 133 0.015
positive regulation of gene expression GO:0010628 290 0.015
membrane organization GO:0061024 112 0.015
nuclear division GO:0000280 332 0.015
ameboidal type cell migration GO:0001667 151 0.015
organonitrogen compound biosynthetic process GO:1901566 117 0.014
regulation of catabolic process GO:0009894 170 0.014
positive regulation of cell motility GO:2000147 3 0.014
immune system process GO:0002376 347 0.014
nephron development GO:0072006 3 0.014
organelle localization GO:0051640 148 0.014
response to oxidative stress GO:0006979 86 0.014
spermatid development GO:0007286 98 0.014
defense response to gram negative bacterium GO:0050829 94 0.014
regulation of programmed cell death GO:0043067 152 0.014
regulation of vesicle mediated transport GO:0060627 59 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
positive regulation of macromolecule metabolic process GO:0010604 405 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
death GO:0016265 284 0.014
positive regulation of molecular function GO:0044093 136 0.014
purine containing compound catabolic process GO:0072523 112 0.014
body morphogenesis GO:0010171 2 0.014
wing disc morphogenesis GO:0007472 344 0.014
localization of cell GO:0051674 257 0.014
response to lipopolysaccharide GO:0032496 4 0.014
positive regulation of cell migration GO:0030335 2 0.014
cellular macromolecule localization GO:0070727 220 0.014
ribose phosphate metabolic process GO:0019693 145 0.014
regulation of response to stress GO:0080134 200 0.014
cytoplasmic transport GO:0016482 130 0.014
lipid metabolic process GO:0006629 121 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.013
inorganic ion transmembrane transport GO:0098660 73 0.013
Mouse
purine nucleoside catabolic process GO:0006152 112 0.013
phosphate ion transport GO:0006817 4 0.013
macromolecule catabolic process GO:0009057 161 0.013
transmembrane transport GO:0055085 139 0.013
Mouse
positive regulation of phosphate metabolic process GO:0045937 139 0.013
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.013
dna metabolic process GO:0006259 227 0.013
regulation of cell death GO:0010941 173 0.013
establishment of protein localization GO:0045184 163 0.013
behavioral response to ethanol GO:0048149 49 0.013
notch signaling pathway GO:0007219 120 0.013
cell fate determination GO:0001709 91 0.013
mitotic spindle organization GO:0007052 220 0.013
response to external biotic stimulus GO:0043207 293 0.013
smoothened signaling pathway GO:0007224 49 0.013
epithelium migration GO:0090132 148 0.013
autophagy GO:0006914 108 0.013
amine metabolic process GO:0009308 12 0.013
gland development GO:0048732 191 0.013
tripartite regional subdivision GO:0007351 103 0.013
vesicle organization GO:0016050 44 0.013
positive regulation of rna biosynthetic process GO:1902680 266 0.012
establishment of organelle localization GO:0051656 122 0.012
regulation of epithelial cell differentiation GO:0030856 4 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
divalent metal ion transport GO:0070838 26 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
immune response GO:0006955 246 0.012
cell migration GO:0016477 238 0.012
response to light stimulus GO:0009416 124 0.012
regulation of cell cycle GO:0051726 291 0.012
positive regulation of hydrolase activity GO:0051345 78 0.012
negative regulation of developmental process GO:0051093 201 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.012
nucleoside catabolic process GO:0009164 112 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
cholesterol transport GO:0030301 2 0.012
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
response to monosaccharide GO:0034284 4 0.012
chaeta development GO:0022416 97 0.012
glycoprotein metabolic process GO:0009100 41 0.012
blastoderm segmentation GO:0007350 159 0.012
microtubule based movement GO:0007018 51 0.012
regulation of hydrolase activity GO:0051336 97 0.012
ribonucleoside metabolic process GO:0009119 127 0.012
response to hexose GO:0009746 3 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
protein phosphorylation GO:0006468 169 0.012
sensory organ morphogenesis GO:0090596 260 0.012
neuromuscular synaptic transmission GO:0007274 67 0.011
nucleotide metabolic process GO:0009117 161 0.011
regulation of phosphorylation GO:0042325 147 0.011
sensory perception GO:0007600 196 0.011
cellular amine metabolic process GO:0044106 12 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
brain development GO:0007420 120 0.011
response to radiation GO:0009314 155 0.011
regulation of intracellular signal transduction GO:1902531 236 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
purine nucleoside metabolic process GO:0042278 127 0.011
ribonucleotide metabolic process GO:0009259 145 0.011
cation transport GO:0006812 110 0.011
Mouse
columnar cuboidal epithelial cell development GO:0002066 249 0.011
nucleotide catabolic process GO:0009166 109 0.011
regulation of cell proliferation GO:0042127 163 0.011
cilium morphogenesis GO:0060271 39 0.011
regulation of lipid transport GO:0032368 3 0.011
rna localization GO:0006403 115 0.011
benzene containing compound metabolic process GO:0042537 3 0.011
cellular amide metabolic process GO:0043603 80 0.011
store operated calcium entry GO:0002115 3 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
negative regulation of cell communication GO:0010648 223 0.011
tissue migration GO:0090130 155 0.011
actin filament based process GO:0030029 220 0.011
glycosyl compound metabolic process GO:1901657 127 0.011
apoptotic process GO:0006915 159 0.011
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.011
chemical homeostasis GO:0048878 92 0.011
Mouse
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
kidney epithelium development GO:0072073 3 0.011
response to other organism GO:0051707 293 0.010
negative regulation of epithelial cell proliferation GO:0050680 4 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010
nephron epithelium development GO:0072009 3 0.010
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
response to alcohol GO:0097305 95 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
negative regulation of multicellular organismal process GO:0051241 142 0.010
chromosome segregation GO:0007059 157 0.010
multi organism behavior GO:0051705 175 0.010
regulation of immune response GO:0050776 118 0.010
intracellular protein transport GO:0006886 104 0.010
negative regulation of gene expression GO:0010629 387 0.010
protein complex assembly GO:0006461 200 0.010
detection of light stimulus GO:0009583 58 0.010
response to bacterium GO:0009617 198 0.010
response to organophosphorus GO:0046683 2 0.010
pigmentation GO:0043473 75 0.010

Nhe1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of metabolism DOID:0014667 0 0.043
disease of anatomical entity DOID:7 0 0.041
inherited metabolic disorder DOID:655 0 0.032
musculoskeletal system disease DOID:17 0 0.015
nervous system disease DOID:863 0 0.015
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
sensory system disease DOID:0050155 0 0.010
central nervous system disease DOID:331 0 0.010