Drosophila melanogaster

88 known processes

pdm2 (Dmel_CG12287)

POU domain protein 2

(Aliases: CG15487,CG15486,dPOU-28,Pdm2,Dmel\CG12287,dim,dOct2,CG12287,Oct2,Pdm,Pdm-2,Oct-2,pdm,miti,dpou28,dPOU28,pdm-2,dPOU28/pdm-2)

pdm2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.871
Human Fly
stem cell differentiation GO:0048863 117 0.863
negative regulation of transcription dna templated GO:0045892 237 0.852
Human
negative regulation of nucleic acid templated transcription GO:1903507 240 0.850
Human Fly
negative regulation of rna biosynthetic process GO:1902679 240 0.829
Human Fly
tissue morphogenesis GO:0048729 297 0.819
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.779
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.758
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.756
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.749
positive regulation of rna metabolic process GO:0051254 271 0.748
regulation of multicellular organismal development GO:2000026 414 0.738
Fly
multi organism behavior GO:0051705 175 0.729
positive regulation of macromolecule metabolic process GO:0010604 405 0.726
transcription from rna polymerase ii promoter GO:0006366 368 0.716
negative regulation of cellular biosynthetic process GO:0031327 277 0.709
Human Fly
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.632
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.627
Human Fly
regionalization GO:0003002 416 0.600
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.595
positive regulation of rna biosynthetic process GO:1902680 266 0.574
positive regulation of biosynthetic process GO:0009891 316 0.547
positive regulation of gene expression GO:0010628 290 0.535
axon development GO:0061564 297 0.533
Fly
blastoderm segmentation GO:0007350 159 0.529
dendrite morphogenesis GO:0048813 199 0.528
Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.501
Human Fly
negative regulation of rna metabolic process GO:0051253 251 0.491
Human Fly
morphogenesis of an epithelium GO:0002009 276 0.474
Mouse
embryonic pattern specification GO:0009880 174 0.448
negative regulation of gene expression GO:0010629 387 0.446
Human
axonogenesis GO:0007409 290 0.428
Fly
reproductive behavior GO:0019098 122 0.417
appendage development GO:0048736 401 0.408
negative regulation of biosynthetic process GO:0009890 277 0.400
Human Fly
circulatory system development GO:0072359 82 0.399
positive regulation of cellular biosynthetic process GO:0031328 316 0.397
heart development GO:0007507 82 0.395
neuroblast differentiation GO:0014016 29 0.383
negative regulation of cellular metabolic process GO:0031324 382 0.378
Human Fly
negative regulation of developmental process GO:0051093 201 0.350
Worm
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.331
Human
myoblast proliferation GO:0051450 3 0.320
regulation of nervous system development GO:0051960 248 0.319
Fly
regulation of cell fate commitment GO:0010453 29 0.312
eye antennal disc morphogenesis GO:0007455 34 0.298
locomotory behavior GO:0007626 176 0.292
Fly
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.284
chromatin modification GO:0016568 147 0.283
multi multicellular organism process GO:0044706 123 0.271
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.265
neuron recognition GO:0008038 101 0.250
Fly
cell migration GO:0016477 238 0.233
Worm
negative regulation of multicellular organismal process GO:0051241 142 0.222
Worm
localization of cell GO:0051674 257 0.221
Worm
multicellular organismal reproductive behavior GO:0033057 110 0.219
cardiovascular system development GO:0072358 82 0.219
brain development GO:0007420 120 0.215
Fly
negative regulation of cell differentiation GO:0045596 143 0.213
Worm
neural precursor cell proliferation GO:0061351 75 0.205
synaptic transmission GO:0007268 288 0.204
embryonic morphogenesis GO:0048598 206 0.201
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.199
leg disc development GO:0035218 92 0.198
dendrite guidance GO:0070983 21 0.196
Fly
stem cell development GO:0048864 79 0.192
neuron projection guidance GO:0097485 241 0.191
Fly
chromatin organization GO:0006325 207 0.191
taxis GO:0042330 304 0.184
Fly
body morphogenesis GO:0010171 2 0.183
growth GO:0040007 359 0.182
dendrite development GO:0016358 204 0.180
Fly
neuron fate commitment GO:0048663 50 0.178
tube development GO:0035295 244 0.176
motor neuron axon guidance GO:0008045 58 0.174
Fly
multi organism reproductive behavior GO:0044705 121 0.172
central nervous system development GO:0007417 201 0.172
epithelial cell differentiation GO:0030855 322 0.170
Mouse
negative regulation of growth GO:0045926 84 0.155
negative regulation of nervous system development GO:0051961 92 0.153
regulation of protein metabolic process GO:0051246 256 0.147
histone methylation GO:0016571 40 0.145
establishment of localization in cell GO:0051649 402 0.145
Mouse
regulation of synapse structure and activity GO:0050803 128 0.143
cell junction assembly GO:0034329 42 0.143
neuroblast development GO:0014019 13 0.140
segmentation GO:0035282 207 0.137
Fly
tube morphogenesis GO:0035239 191 0.136
cell fate determination GO:0001709 91 0.133
regulation of synaptic activity GO:0060025 9 0.127
positive regulation of multicellular organismal process GO:0051240 143 0.123
axon midline choice point recognition GO:0016199 26 0.122
muscle organ development GO:0007517 127 0.122
response to alcohol GO:0097305 95 0.118
skeletal muscle organ development GO:0060538 48 0.116
covalent chromatin modification GO:0016569 106 0.115
neuroblast fate commitment GO:0014017 19 0.113
camera type eye development GO:0043010 4 0.112
Mouse
camera type eye morphogenesis GO:0048593 2 0.110
Mouse
positive regulation of developmental process GO:0051094 143 0.108
epithelial tube morphogenesis GO:0060562 88 0.108
connective tissue development GO:0061448 3 0.106
cell proliferation GO:0008283 299 0.105
negative regulation of cell communication GO:0010648 223 0.104
digestive tract morphogenesis GO:0048546 127 0.103
establishment or maintenance of cell polarity GO:0007163 167 0.103
gastrulation GO:0007369 70 0.103
muscle structure development GO:0061061 224 0.103
compound eye development GO:0048749 307 0.102
regulation of neurogenesis GO:0050767 158 0.101
Fly
ameboidal type cell migration GO:0001667 151 0.101
head development GO:0060322 135 0.100
Fly
exocrine system development GO:0035272 162 0.099
positive regulation of cell proliferation GO:0008284 47 0.097
imaginal disc derived appendage morphogenesis GO:0035114 395 0.097
renal tubule development GO:0061326 64 0.096
regulation of cell cycle GO:0051726 291 0.094
regulation of cell development GO:0060284 215 0.094
Worm Fly
neuron fate determination GO:0048664 1 0.094
kidney epithelium development GO:0072073 3 0.093
regulation of cell proliferation GO:0042127 163 0.091
cell cell signaling involved in cell fate commitment GO:0045168 210 0.090
Mouse
cell junction organization GO:0034330 57 0.088
morphogenesis of a polarized epithelium GO:0001738 93 0.088
chromatin remodeling GO:0006338 72 0.088
embryonic axis specification GO:0000578 107 0.087
epidermis development GO:0008544 65 0.087
Mouse Rat Worm
histone modification GO:0016570 106 0.085
mating behavior GO:0007617 106 0.085
compound eye photoreceptor cell differentiation GO:0001751 140 0.085
axon choice point recognition GO:0016198 26 0.084
salivary gland development GO:0007431 162 0.083
chromosome organization GO:0051276 360 0.082
regulation of molecular function GO:0065009 217 0.081
cell cycle dna replication GO:0044786 23 0.081
male mating behavior GO:0060179 70 0.079
single organism biosynthetic process GO:0044711 206 0.079
regulation of neuron differentiation GO:0045664 103 0.079
Fly
developmental growth GO:0048589 280 0.078
mesenchymal cell differentiation GO:0048762 1 0.078
cell death GO:0008219 279 0.078
single organism behavior GO:0044708 391 0.077
Fly
intracellular signal transduction GO:0035556 300 0.076
regulation of phosphate metabolic process GO:0019220 210 0.076
cardiac cell fate commitment GO:0060911 17 0.076
post embryonic appendage morphogenesis GO:0035120 385 0.075
limb morphogenesis GO:0035108 1 0.075
kidney development GO:0001822 3 0.075
regulation of cell differentiation GO:0045595 302 0.074
Worm Fly
cell recognition GO:0008037 102 0.074
Fly
heart morphogenesis GO:0003007 32 0.074
renal system development GO:0072001 72 0.072
digestive system development GO:0055123 149 0.072
neuroepithelial cell differentiation GO:0060563 6 0.070
catabolic process GO:0009056 409 0.069
gland development GO:0048732 191 0.069
hindgut development GO:0061525 58 0.068
positive regulation of neurogenesis GO:0050769 41 0.067
regulation of stem cell proliferation GO:0072091 40 0.067
eye antennal disc development GO:0035214 60 0.066
regulation of histone modification GO:0031056 20 0.065
negative regulation of neurogenesis GO:0050768 53 0.065
organonitrogen compound metabolic process GO:1901564 318 0.064
Fly
embryonic hindgut morphogenesis GO:0048619 48 0.064
regulation of phosphorus metabolic process GO:0051174 210 0.063
anterior posterior axis specification GO:0009948 109 0.063
response to ecdysone GO:0035075 34 0.063
malpighian tubule morphogenesis GO:0007443 44 0.063
cellular protein modification process GO:0006464 438 0.062
cell motility GO:0048870 251 0.061
Worm
forebrain development GO:0030900 2 0.061
gliogenesis GO:0042063 80 0.061
imaginal disc derived appendage development GO:0048737 399 0.060
renal tubule morphogenesis GO:0061333 44 0.060
regulation of chromatin organization GO:1902275 32 0.060
dorsal ventral pattern formation GO:0009953 133 0.059
regulation of programmed cell death GO:0043067 152 0.058
spinal cord development GO:0021510 1 0.058
organic substance catabolic process GO:1901575 308 0.058
developmental maturation GO:0021700 172 0.058
Mouse Worm
death GO:0016265 284 0.057
salivary gland morphogenesis GO:0007435 145 0.057
neuroblast fate determination GO:0007400 12 0.057
regulation of chromosome organization GO:0033044 64 0.057
male gamete generation GO:0048232 201 0.057
positive regulation of cell communication GO:0010647 250 0.056
periodic partitioning GO:0007365 29 0.056
regulation of cell death GO:0010941 173 0.056
response to biotic stimulus GO:0009607 294 0.055
Fly
positive regulation of signaling GO:0023056 243 0.054
negative regulation of response to stimulus GO:0048585 258 0.054
reproductive structure development GO:0048608 74 0.053
cardioblast cell fate commitment GO:0042684 14 0.053
eye photoreceptor cell differentiation GO:0001754 145 0.053
eye photoreceptor cell fate commitment GO:0042706 37 0.053
positive regulation of neuron differentiation GO:0045666 26 0.052
regulation of intracellular signal transduction GO:1902531 236 0.052
regulation of chromatin modification GO:1903308 28 0.052
stem cell division GO:0017145 69 0.051
response to organic substance GO:0010033 284 0.051
regulation of anatomical structure morphogenesis GO:0022603 242 0.051
Fly
digestive tract development GO:0048565 149 0.050
urogenital system development GO:0001655 72 0.049
skeletal muscle tissue development GO:0007519 13 0.049
stem cell proliferation GO:0072089 88 0.049
compound eye morphogenesis GO:0001745 249 0.048
hindgut morphogenesis GO:0007442 58 0.047
lateral inhibition GO:0046331 206 0.047
aggressive behavior GO:0002118 63 0.047
carbohydrate derivative metabolic process GO:1901135 217 0.046
regulation of cellular protein metabolic process GO:0032268 243 0.046
regulation of synaptic transmission GO:0050804 69 0.046
purine containing compound metabolic process GO:0072521 155 0.045
negative regulation of programmed cell death GO:0043069 72 0.045
axon guidance GO:0007411 233 0.045
Fly
small molecule metabolic process GO:0044281 305 0.045
retina development in camera type eye GO:0060041 4 0.045
negative regulation of signaling GO:0023057 219 0.045
positive regulation of protein metabolic process GO:0051247 128 0.044
positive regulation of phosphorus metabolic process GO:0010562 139 0.044
embryonic epithelial tube formation GO:0001838 6 0.044
axis specification GO:0009798 167 0.043
organ formation GO:0048645 39 0.043
regulation of apoptotic process GO:0042981 130 0.043
embryonic heart tube development GO:0035050 22 0.042
skin development GO:0043588 65 0.042
Mouse Rat Worm
nucleoside phosphate metabolic process GO:0006753 162 0.042
positive regulation of nervous system development GO:0051962 69 0.042
regulation of small gtpase mediated signal transduction GO:0051056 93 0.041
telencephalon development GO:0021537 2 0.041
compound eye photoreceptor fate commitment GO:0001752 36 0.041
regulation of embryonic cell shape GO:0016476 30 0.040
development of primary sexual characteristics GO:0045137 50 0.040
antennal development GO:0007469 25 0.040
positive regulation of cellular protein metabolic process GO:0032270 118 0.039
negative regulation of cell death GO:0060548 81 0.039
cell growth GO:0016049 108 0.039
cognition GO:0050890 141 0.039
limb development GO:0060173 1 0.039
protein alkylation GO:0008213 43 0.038
tissue death GO:0016271 102 0.038
ribonucleoside triphosphate catabolic process GO:0009203 108 0.038
epithelial cell development GO:0002064 274 0.038
cardiac cell fate determination GO:0060913 3 0.038
meiotic cell cycle GO:0051321 171 0.038
cardioblast differentiation GO:0010002 20 0.037
regulation of localization GO:0032879 275 0.037
cellular catabolic process GO:0044248 372 0.037
positive regulation of cellular component organization GO:0051130 156 0.036
anterior posterior pattern specification GO:0009952 136 0.036
learning GO:0007612 75 0.036
programmed cell death GO:0012501 257 0.036
learning or memory GO:0007611 141 0.035
muscle tissue morphogenesis GO:0060415 2 0.035
nucleobase containing small molecule metabolic process GO:0055086 174 0.035
nephron development GO:0072006 3 0.034
response to wounding GO:0009611 94 0.034
Mouse
regulation of cellular amino acid metabolic process GO:0006521 0 0.034
cellular response to organic substance GO:0071310 132 0.034
actin filament based movement GO:0030048 26 0.034
outflow tract morphogenesis GO:0003151 4 0.034
appendage morphogenesis GO:0035107 397 0.033
neuroblast proliferation GO:0007405 74 0.033
regulation of cellular amine metabolic process GO:0033238 3 0.032
cellular amino acid metabolic process GO:0006520 61 0.032
glial cell differentiation GO:0010001 35 0.032
regulation of purine nucleotide metabolic process GO:1900542 62 0.032
positive regulation of programmed cell death GO:0043068 62 0.032
meiotic nuclear division GO:0007126 151 0.032
regulation of antimicrobial humoral response GO:0002759 50 0.032
Fly
regulation of response to stress GO:0080134 200 0.031
positive regulation of response to stimulus GO:0048584 323 0.031
Fly
regulation of embryonic development GO:0045995 68 0.031
gonad development GO:0008406 50 0.031
positive regulation of cell development GO:0010720 61 0.031
mating GO:0007618 120 0.031
negative regulation of cell cycle GO:0045786 116 0.030
chaeta development GO:0022416 97 0.030
retina morphogenesis in camera type eye GO:0060042 2 0.030
nephron tubule development GO:0072080 3 0.030
spermatogenesis GO:0007283 200 0.030
imaginal disc derived leg morphogenesis GO:0007480 80 0.030
muscle tissue development GO:0060537 30 0.030
nuclear division GO:0000280 332 0.030
cell maturation GO:0048469 144 0.030
Mouse Worm
regulation of phosphorylation GO:0042325 147 0.030
wound healing GO:0042060 75 0.029
Mouse
response to oxygen containing compound GO:1901700 200 0.029
defense response GO:0006952 300 0.029
wing disc morphogenesis GO:0007472 344 0.029
nephron epithelium development GO:0072009 3 0.029
cardiocyte differentiation GO:0035051 29 0.029
negative regulation of apoptotic process GO:0043066 63 0.029
regulation of mitotic cell cycle GO:0007346 190 0.029
positive regulation of cellular amine metabolic process GO:0033240 0 0.028
ion transport GO:0006811 145 0.028
eye development GO:0001654 323 0.028
Mouse
negative regulation of developmental growth GO:0048640 64 0.028
ribose phosphate metabolic process GO:0019693 145 0.028
photoreceptor cell fate commitment GO:0046552 41 0.028
central nervous system neuron differentiation GO:0021953 8 0.028
response to sterol GO:0036314 34 0.028
purine ribonucleotide metabolic process GO:0009150 145 0.028
organelle fission GO:0048285 340 0.027
sensory perception of salty taste GO:0050914 3 0.027
synaptic target recognition GO:0008039 45 0.027
Fly
positive regulation of phosphate metabolic process GO:0045937 139 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
negative regulation of cellular component organization GO:0051129 108 0.027
long term memory GO:0007616 62 0.027
negative regulation of signal transduction GO:0009968 206 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.026
photoreceptor cell differentiation GO:0046530 170 0.026
vesicle mediated transport GO:0016192 381 0.026
stem cell fate commitment GO:0048865 25 0.026
regulation of cell shape GO:0008360 113 0.026
methylation GO:0032259 47 0.025
regulation of transcription regulatory region dna binding GO:2000677 3 0.025
small gtpase mediated signal transduction GO:0007264 88 0.025
regulation of epithelial cell differentiation GO:0030856 4 0.025
positive regulation of cell differentiation GO:0045597 64 0.025
anterior posterior axis specification embryo GO:0008595 103 0.025
ventral cord development GO:0007419 16 0.025
kidney morphogenesis GO:0060993 3 0.025
endocytosis GO:0006897 310 0.025
protein localization GO:0008104 284 0.024
Mouse
dna endoreduplication GO:0042023 22 0.024
segment polarity determination GO:0007367 25 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
protein modification process GO:0036211 438 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.024
memory GO:0007613 94 0.024
establishment of planar polarity GO:0001736 87 0.024
regulation of multi organism process GO:0043900 131 0.024
Human Worm Fly
heart formation GO:0060914 6 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
histolysis GO:0007559 102 0.023
regulation of cell fate specification GO:0042659 27 0.023
imaginal disc derived wing morphogenesis GO:0007476 337 0.023
cell division GO:0051301 248 0.023
pigment cell differentiation GO:0050931 3 0.022
actin mediated cell contraction GO:0070252 21 0.022
carbohydrate derivative biosynthetic process GO:1901137 85 0.022
apical constriction GO:0003383 18 0.022
gland morphogenesis GO:0022612 145 0.022
chromosome segregation GO:0007059 157 0.021
carboxylic acid metabolic process GO:0019752 92 0.021
ovarian follicle cell development GO:0030707 248 0.021
phosphorylation GO:0016310 294 0.021
neuron remodeling GO:0016322 29 0.021
antimicrobial humoral response GO:0019730 99 0.021
Fly
establishment of ommatidial planar polarity GO:0042067 49 0.021
regulation of notch signaling pathway GO:0008593 100 0.021
notch signaling pathway GO:0007219 120 0.021
asymmetric neuroblast division GO:0055059 33 0.021
stem cell maintenance GO:0019827 67 0.021
regulation of protein modification process GO:0031399 112 0.021
dna metabolic process GO:0006259 227 0.021
cell migration involved in gastrulation GO:0042074 9 0.021
posttranscriptional gene silencing by rna GO:0035194 45 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.021
heterocycle catabolic process GO:0046700 166 0.020
tripartite regional subdivision GO:0007351 103 0.020
neuron maturation GO:0042551 31 0.020
segment specification GO:0007379 33 0.020
aromatic compound catabolic process GO:0019439 166 0.020
inositol lipid mediated signaling GO:0048017 4 0.020
gene silencing GO:0016458 138 0.020
salt aversion GO:0035199 3 0.020
posttranscriptional regulation of gene expression GO:0010608 145 0.020
nucleobase containing compound catabolic process GO:0034655 165 0.020
macromolecule methylation GO:0043414 45 0.020
respiratory system development GO:0060541 213 0.020
Mouse
regulation of gtp catabolic process GO:0033124 44 0.019
salivary gland histolysis GO:0035070 88 0.019
acetylcholine metabolic process GO:0008291 2 0.019
regulation of cellular localization GO:0060341 136 0.019
behavioral response to ethanol GO:0048149 49 0.019
positive regulation of nucleoside metabolic process GO:0045979 47 0.019
amine metabolic process GO:0009308 12 0.019
regulation of neuroblast proliferation GO:1902692 34 0.019
malpighian tubule development GO:0072002 64 0.019
macromolecule catabolic process GO:0009057 161 0.019
salivary gland cell autophagic cell death GO:0035071 83 0.019
organelle assembly GO:0070925 198 0.018
developmental programmed cell death GO:0010623 138 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
striated muscle tissue development GO:0014706 27 0.018
organophosphate metabolic process GO:0019637 195 0.018
negative regulation of cell fate commitment GO:0010454 17 0.018
mesoderm development GO:0007498 78 0.018
negative regulation of cellular protein metabolic process GO:0032269 85 0.018
imaginal disc pattern formation GO:0007447 91 0.018
pigmentation GO:0043473 75 0.018
protein methylation GO:0006479 43 0.018
glial cell development GO:0021782 27 0.017
regulation of catabolic process GO:0009894 170 0.017
adult behavior GO:0030534 137 0.017
Fly
ectodermal placode morphogenesis GO:0071697 4 0.017
Mouse
purine nucleoside catabolic process GO:0006152 112 0.017
response to other organism GO:0051707 293 0.017
Fly
ribonucleotide catabolic process GO:0009261 109 0.017
male courtship behavior GO:0008049 63 0.017
intracellular mrna localization GO:0008298 66 0.017
nephron morphogenesis GO:0072028 3 0.017
mesenchymal cell development GO:0014031 1 0.017
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.017
sensory organ morphogenesis GO:0090596 260 0.016
Mouse
embryo development ending in birth or egg hatching GO:0009792 152 0.016
Worm
asymmetric stem cell division GO:0098722 49 0.016
positive regulation of protein modification process GO:0031401 58 0.016
negative regulation of organelle organization GO:0010639 56 0.016
oviposition GO:0018991 19 0.016
somatic muscle development GO:0007525 66 0.016
regulation of cell projection organization GO:0031344 92 0.016
Fly
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.016
apoptotic process GO:0006915 159 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
negative regulation of molecular function GO:0044092 51 0.016
positive regulation of organelle organization GO:0010638 65 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
courtship behavior GO:0007619 68 0.016
single organism catabolic process GO:0044712 228 0.016
ras protein signal transduction GO:0007265 88 0.016
response to external biotic stimulus GO:0043207 293 0.016
Fly
positive regulation of cell migration GO:0030335 2 0.016
sex determination GO:0007530 18 0.016
regulation of response to biotic stimulus GO:0002831 63 0.016
Fly
rhythmic behavior GO:0007622 76 0.016
catecholamine biosynthetic process GO:0042423 3 0.016
cellular macromolecule localization GO:0070727 220 0.015
regulation of immune system process GO:0002682 176 0.015
Fly
regulation of organelle organization GO:0033043 196 0.015
regulation of catalytic activity GO:0050790 185 0.015
rna localization GO:0006403 115 0.015
immune response activating signal transduction GO:0002757 2 0.015
regulation of nucleotide metabolic process GO:0006140 62 0.015
response to bacterium GO:0009617 198 0.015
cellular response to mechanical stimulus GO:0071260 2 0.015
eye morphogenesis GO:0048592 260 0.015
Mouse
response to lipid GO:0033993 38 0.015
convergent extension GO:0060026 2 0.014
regulation of organ morphogenesis GO:2000027 78 0.014
positive regulation of cell death GO:0010942 69 0.014
nephron tubule morphogenesis GO:0072078 3 0.014
sex differentiation GO:0007548 81 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
negative regulation of epithelial cell proliferation GO:0050680 4 0.014
non sensory hair organization GO:0035316 47 0.014
head segmentation GO:0035287 13 0.014
neuron fate specification GO:0048665 12 0.014
nitrogen compound transport GO:0071705 85 0.014
regulation of cell cycle process GO:0010564 181 0.014
extrinsic apoptotic signaling pathway GO:0097191 1 0.014
response to organic cyclic compound GO:0014070 89 0.014
regulation of neural precursor cell proliferation GO:2000177 35 0.014
wing disc pattern formation GO:0035222 66 0.014
developmental pigmentation GO:0048066 68 0.014
hindbrain development GO:0030902 2 0.014
vitamin metabolic process GO:0006766 2 0.014
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.014
response to ketone GO:1901654 34 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
negative regulation of synapse assembly GO:0051964 39 0.013
single organism cellular localization GO:1902580 180 0.013
positive regulation of hydrolase activity GO:0051345 78 0.013
regulation of transport GO:0051049 181 0.013
autophagic cell death GO:0048102 83 0.013
induction of programmed cell death by hormones GO:0035081 12 0.013
establishment of organelle localization GO:0051656 122 0.013
positive regulation of molecular function GO:0044093 136 0.013
musculoskeletal movement GO:0050881 3 0.013
response to organophosphorus GO:0046683 2 0.013
secretion GO:0046903 109 0.013
Mouse
regulation of response to external stimulus GO:0032101 115 0.013
Fly
negative regulation of protein metabolic process GO:0051248 85 0.013
establishment of tissue polarity GO:0007164 87 0.013
regeneration GO:0031099 16 0.013
positive regulation of nucleotide metabolic process GO:0045981 55 0.013
negative regulation of cell proliferation GO:0008285 69 0.013
nucleoside metabolic process GO:0009116 127 0.013
nucleoside catabolic process GO:0009164 112 0.013
negative regulation of intracellular signal transduction GO:1902532 57 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.012
homeostatic process GO:0042592 199 0.012
positive regulation of cell motility GO:2000147 3 0.012
negative regulation of neuron differentiation GO:0045665 16 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012

pdm2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
waardenburg s syndrome DOID:9258 0 0.141
cancer DOID:162 0 0.113
disease of cellular proliferation DOID:14566 0 0.113
organ system cancer DOID:0050686 0 0.113
musculoskeletal system cancer DOID:0060100 0 0.034
disease of anatomical entity DOID:7 0 0.016