Drosophila melanogaster

71 known processes

gw (Dmel_CG31992)

gawky

(Aliases: GW182,CG31992,CG9905,Dmel\CG31992,anon-EST:Posey205,dGW182,CG11484)

gw biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
circadian rhythm GO:0007623 105 0.886
locomotory behavior GO:0007626 176 0.665
locomotor rhythm GO:0045475 56 0.631
rhythmic process GO:0048511 106 0.565
single organism behavior GO:0044708 391 0.446
negative regulation of multicellular organismal process GO:0051241 142 0.352
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.332
negative regulation of gene expression GO:0010629 387 0.331
dendrite development GO:0016358 204 0.323
negative regulation of cellular metabolic process GO:0031324 382 0.260
regulation of neurogenesis GO:0050767 158 0.245
cell cycle checkpoint GO:0000075 95 0.234
circadian behavior GO:0048512 76 0.221
enzyme linked receptor protein signaling pathway GO:0007167 179 0.210
negative regulation of signal transduction GO:0009968 206 0.190
learning or memory GO:0007611 141 0.183
posttranscriptional regulation of gene expression GO:0010608 145 0.179
positive regulation of transcription dna templated GO:0045893 266 0.173
positive regulation of cellular biosynthetic process GO:0031328 316 0.171
negative regulation of signaling GO:0023057 219 0.168
mrna processing GO:0006397 104 0.155
regulation of anatomical structure morphogenesis GO:0022603 242 0.155
immune system process GO:0002376 347 0.147
cellular response to organic substance GO:0071310 132 0.141
regulation of cell cycle phase transition GO:1901987 130 0.141
cellular protein modification process GO:0006464 438 0.139
mitotic cell cycle checkpoint GO:0007093 88 0.132
rna catabolic process GO:0006401 37 0.118
negative regulation of cellular protein metabolic process GO:0032269 85 0.113
transcription from rna polymerase ii promoter GO:0006366 368 0.109
macromolecular complex assembly GO:0065003 256 0.103
positive regulation of biosynthetic process GO:0009891 316 0.093
protein modification process GO:0036211 438 0.089
neurological system process GO:0050877 358 0.084
immune response GO:0006955 246 0.083
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.081
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.079
cellular response to dna damage stimulus GO:0006974 223 0.079
negative regulation of cell communication GO:0010648 223 0.073
ncrna metabolic process GO:0034660 43 0.073
organic substance catabolic process GO:1901575 308 0.071
central nervous system development GO:0007417 201 0.069
cellular macromolecule catabolic process GO:0044265 136 0.069
rhythmic behavior GO:0007622 76 0.068
purine containing compound metabolic process GO:0072521 155 0.068
cellular macromolecule localization GO:0070727 220 0.067
dendrite morphogenesis GO:0048813 199 0.065
negative regulation of rna biosynthetic process GO:1902679 240 0.065
catabolic process GO:0009056 409 0.064
cellular nitrogen compound catabolic process GO:0044270 165 0.062
eye morphogenesis GO:0048592 260 0.061
gene silencing by mirna GO:0035195 22 0.059
adult locomotory behavior GO:0008344 76 0.056
translation GO:0006412 69 0.055
regulation of growth GO:0040008 233 0.054
spindle organization GO:0007051 253 0.054
regulation of nervous system development GO:0051960 248 0.053
organelle fission GO:0048285 340 0.053
adult behavior GO:0030534 137 0.052
protein catabolic process GO:0030163 101 0.049
mrna metabolic process GO:0016071 124 0.049
innate immune response GO:0045087 144 0.047
cellular protein localization GO:0034613 160 0.047
negative regulation of protein metabolic process GO:0051248 85 0.047
small molecule metabolic process GO:0044281 305 0.047
regulation of neuron differentiation GO:0045664 103 0.046
defense response GO:0006952 300 0.046
positive regulation of rna biosynthetic process GO:1902680 266 0.045
regulation of cellular protein metabolic process GO:0032268 243 0.045
regulation of cell proliferation GO:0042127 163 0.045
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.044
cellular catabolic process GO:0044248 372 0.043
cytoplasmic transport GO:0016482 130 0.043
cellular response to endogenous stimulus GO:0071495 80 0.042
head development GO:0060322 135 0.041
negative regulation of rna metabolic process GO:0051253 251 0.040
inter male aggressive behavior GO:0002121 60 0.039
cellular response to organonitrogen compound GO:0071417 36 0.038
dna integrity checkpoint GO:0031570 81 0.037
protein ubiquitination GO:0016567 70 0.037
ubiquitin dependent protein catabolic process GO:0006511 78 0.037
body morphogenesis GO:0010171 2 0.037
regulation of developmental growth GO:0048638 174 0.037
eye photoreceptor cell differentiation GO:0001754 145 0.036
imaginal disc derived appendage development GO:0048737 399 0.036
chaeta development GO:0022416 97 0.036
negative regulation of cellular biosynthetic process GO:0031327 277 0.035
taxis GO:0042330 304 0.035
positive regulation of gene expression GO:0010628 290 0.033
regulation of mitotic cell cycle GO:0007346 190 0.033
protein complex assembly GO:0006461 200 0.033
protein modification by small protein conjugation or removal GO:0070647 106 0.033
modification dependent macromolecule catabolic process GO:0043632 79 0.032
response to organic substance GO:0010033 284 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.032
regulation of translation GO:0006417 56 0.031
purine ribonucleoside metabolic process GO:0046128 127 0.031
developmental growth GO:0048589 280 0.030
protein complex biogenesis GO:0070271 201 0.030
macromolecule catabolic process GO:0009057 161 0.029
organic substance transport GO:0071702 257 0.029
g2 dna damage checkpoint GO:0031572 69 0.029
cell cycle phase transition GO:0044770 140 0.029
nuclear division GO:0000280 332 0.029
regulation of response to stress GO:0080134 200 0.028
positive regulation of protein metabolic process GO:0051247 128 0.028
cell proliferation GO:0008283 299 0.028
compound eye morphogenesis GO:0001745 249 0.028
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
cellular protein catabolic process GO:0044257 83 0.027
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.027
regulation of hemocyte proliferation GO:0035206 37 0.027
regulation of behavior GO:0050795 75 0.027
nucleoside phosphate catabolic process GO:1901292 110 0.026
compound eye development GO:0048749 307 0.026
death GO:0016265 284 0.026
negative regulation of response to stimulus GO:0048585 258 0.025
organelle inheritance GO:0048308 2 0.025
nucleobase containing compound catabolic process GO:0034655 165 0.025
positive regulation of multicellular organism growth GO:0040018 21 0.024
regulation of cell cycle GO:0051726 291 0.024
synaptic transmission GO:0007268 288 0.024
regulation of catalytic activity GO:0050790 185 0.024
regulation of organ morphogenesis GO:2000027 78 0.024
regulation of defense response GO:0031347 102 0.024
dna metabolic process GO:0006259 227 0.024
appendage morphogenesis GO:0035107 397 0.024
wnt signaling pathway GO:0016055 98 0.024
regulation of multicellular organismal development GO:2000026 414 0.023
regulation of cell division GO:0051302 72 0.023
positive regulation of rna metabolic process GO:0051254 271 0.023
gonad development GO:0008406 50 0.023
positive regulation of nucleic acid templated transcription GO:1903508 266 0.022
negative regulation of developmental growth GO:0048640 64 0.022
organophosphate metabolic process GO:0019637 195 0.022
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.021
morphogenesis of a branching structure GO:0001763 45 0.021
purine ribonucleotide metabolic process GO:0009150 145 0.021
negative regulation of biosynthetic process GO:0009890 277 0.021
gene silencing GO:0016458 138 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
protein localization GO:0008104 284 0.021
positive regulation of response to stimulus GO:0048584 323 0.020
regulation of cellular component size GO:0032535 98 0.020
negative regulation of cell cycle phase transition GO:1901988 103 0.020
regulation of hydrolase activity GO:0051336 97 0.019
regulation of proteolysis GO:0030162 87 0.019
endocytosis GO:0006897 310 0.019
cellular response to chemical stimulus GO:0070887 199 0.019
regulation of protein metabolic process GO:0051246 256 0.018
organic cyclic compound catabolic process GO:1901361 168 0.018
cognition GO:0050890 141 0.018
metal ion transport GO:0030001 74 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
regulation of protein catabolic process GO:0042176 55 0.018
stem cell division GO:0017145 69 0.018
establishment of protein localization GO:0045184 163 0.018
actin cytoskeleton organization GO:0030036 206 0.018
regulation of molecular function GO:0065009 217 0.018
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
positive regulation of growth GO:0045927 75 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
negative regulation of developmental process GO:0051093 201 0.017
humoral immune response GO:0006959 117 0.017
chromatin modification GO:0016568 147 0.017
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.017
growth GO:0040007 359 0.017
response to endogenous stimulus GO:0009719 119 0.017
response to wounding GO:0009611 94 0.017
protein transport GO:0015031 155 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.016
long term memory GO:0007616 62 0.016
carbohydrate derivative metabolic process GO:1901135 217 0.016
negative regulation of cellular component organization GO:0051129 108 0.016
mrna catabolic process GO:0006402 33 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
chemosensory behavior GO:0007635 106 0.016
mitotic nuclear division GO:0007067 213 0.016
negative regulation of nervous system development GO:0051961 92 0.016
positive regulation of immune system process GO:0002684 68 0.015
hematopoietic stem cell differentiation GO:0060218 1 0.015
signal transduction in response to dna damage GO:0042770 3 0.015
dephosphorylation GO:0016311 51 0.015
heterocycle catabolic process GO:0046700 166 0.015
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.015
regulation of immune system process GO:0002682 176 0.015
ribonucleoprotein complex subunit organization GO:0071826 28 0.015
purine nucleotide catabolic process GO:0006195 109 0.015
purine containing compound catabolic process GO:0072523 112 0.014
ribonucleoprotein complex assembly GO:0022618 23 0.014
phosphorylation GO:0016310 294 0.014
negative regulation of cell death GO:0060548 81 0.014
response to external biotic stimulus GO:0043207 293 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
larval development GO:0002164 104 0.013
modification dependent protein catabolic process GO:0019941 78 0.013
axon guidance GO:0007411 233 0.013
purine nucleoside metabolic process GO:0042278 127 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
regulation of cellular protein catabolic process GO:1903362 44 0.013
wound healing GO:0042060 75 0.013
cellular response to abiotic stimulus GO:0071214 58 0.013
chromatin organization GO:0006325 207 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
positive regulation of developmental growth GO:0048639 62 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
defense response to bacterium GO:0042742 178 0.013
regulation of cell cycle process GO:0010564 181 0.013
ribonucleoprotein complex biogenesis GO:0022613 31 0.013
cell death GO:0008219 279 0.013
phagocytosis GO:0006909 215 0.013
chromosome organization GO:0051276 360 0.013
proteasomal protein catabolic process GO:0010498 59 0.013
protein modification by small protein conjugation GO:0032446 79 0.012
protein localization to organelle GO:0033365 82 0.012
response to nitrogen compound GO:1901698 90 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
purine nucleoside catabolic process GO:0006152 112 0.012
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.012
protein acylation GO:0043543 42 0.012
cell division GO:0051301 248 0.012
brain development GO:0007420 120 0.012
prostaglandin biosynthetic process GO:0001516 1 0.012
positive regulation of cellular component organization GO:0051130 156 0.012
negative regulation of molecular function GO:0044092 51 0.012
chemotaxis GO:0006935 249 0.012
nucleocytoplasmic transport GO:0006913 72 0.012
regulation of lipid transport GO:0032368 3 0.012
protein phosphorylation GO:0006468 169 0.012
multicellular organism growth GO:0035264 46 0.012
monovalent inorganic cation transport GO:0015672 40 0.011
positive regulation of cell development GO:0010720 61 0.011
vesicle mediated transport GO:0016192 381 0.011
rna processing GO:0006396 147 0.011
regulation of organelle organization GO:0033043 196 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
negative regulation of organelle organization GO:0010639 56 0.011
positive regulation of developmental process GO:0051094 143 0.011
neuron death GO:0070997 27 0.011
aromatic compound catabolic process GO:0019439 166 0.011
regulation of circadian rhythm GO:0042752 49 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
establishment of protein localization to organelle GO:0072594 62 0.010
regulation of glial cell proliferation GO:0060251 11 0.010
negative regulation of translation GO:0017148 28 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010

gw disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
nervous system disease DOID:863 0 0.022
benign neoplasm DOID:0060072 0 0.010
disease of cellular proliferation DOID:14566 0 0.010