Drosophila melanogaster

47 known processes

mus101 (Dmel_CG11156)

mutagen-sensitive 101

(Aliases: CG11156,mus(1)101,Mus101,mus-101,fs(1)K451,anon-WO0148202.1,DmMus101,mus 101,Dmel\CG11156)

mus101 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.996
non recombinational repair GO:0000726 7 0.987
double strand break repair via nonhomologous end joining GO:0006303 5 0.986
dna conformation change GO:0071103 105 0.984
dna repair GO:0006281 54 0.979
dna geometric change GO:0032392 16 0.973
double strand break repair GO:0006302 26 0.948
reciprocal meiotic recombination GO:0007131 19 0.946
dna double strand break processing GO:0000729 3 0.943
recombinational repair GO:0000725 13 0.926
dna synthesis involved in dna repair GO:0000731 5 0.922
dna duplex unwinding GO:0032508 16 0.917
mitotic g2 dna damage checkpoint GO:0007095 69 0.886
mitotic dna damage checkpoint GO:0044773 74 0.859
telomere maintenance GO:0000723 21 0.851
dna recombination GO:0006310 32 0.848
double strand break repair via homologous recombination GO:0000724 13 0.841
translesion synthesis GO:0019985 2 0.819
meiotic chromosome segregation GO:0045132 59 0.788
cellular response to dna damage stimulus GO:0006974 223 0.766
dna metabolic process GO:0006259 227 0.702
Worm
cell cycle dna replication GO:0044786 23 0.659
mitotic g2 m transition checkpoint GO:0044818 70 0.657
chromosome organization GO:0051276 360 0.657
nuclear dna replication GO:0033260 1 0.654
telomere organization GO:0032200 21 0.651
dna replication GO:0006260 48 0.598
Worm
g2 dna damage checkpoint GO:0031572 69 0.596
reciprocal dna recombination GO:0035825 19 0.593
telomere maintenance via recombination GO:0000722 1 0.588
polarity specification of dorsal ventral axis GO:0009951 6 0.569
female meiosis chromosome segregation GO:0016321 33 0.563
nucleotide excision repair GO:0006289 8 0.559
mitotic recombination GO:0006312 2 0.510
postreplication repair GO:0006301 2 0.508
dna biosynthetic process GO:0071897 24 0.454
dna packaging GO:0006323 91 0.441
dna damage checkpoint GO:0000077 78 0.403
single organism biosynthetic process GO:0044711 206 0.401
negative regulation of g2 m transition of mitotic cell cycle GO:0010972 8 0.367
response to ionizing radiation GO:0010212 32 0.343
Human
cellular nitrogen compound catabolic process GO:0044270 165 0.333
chromosome segregation GO:0007059 157 0.331
eye development GO:0001654 323 0.296
mitotic dna integrity checkpoint GO:0044774 75 0.283
negative regulation of cell cycle process GO:0010948 109 0.276
chromosome condensation GO:0030261 41 0.272
cellular response to ionizing radiation GO:0071479 15 0.263
dna amplification GO:0006277 11 0.233
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.233
response to abiotic stimulus GO:0009628 341 0.231
Human
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.227
nucleobase containing compound catabolic process GO:0034655 165 0.218
response to radiation GO:0009314 155 0.211
Human
dna dependent dna replication GO:0006261 17 0.201
aromatic compound catabolic process GO:0019439 166 0.194
protein dna complex assembly GO:0065004 63 0.184
heterocycle catabolic process GO:0046700 166 0.179
dna replication initiation GO:0006270 6 0.176
meiotic chromosome separation GO:0051307 8 0.168
mitotic cell cycle checkpoint GO:0007093 88 0.167
organelle fission GO:0048285 340 0.164
cellular response to radiation GO:0071478 52 0.162
chorion containing eggshell formation GO:0007304 105 0.160
negative regulation of cell cycle phase transition GO:1901988 103 0.154
organelle assembly GO:0070925 198 0.152
signal transduction in response to dna damage GO:0042770 3 0.148
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.148
transposition rna mediated GO:0032197 3 0.139
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.137
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.133
purine nucleoside metabolic process GO:0042278 127 0.129
regulation of dna repair GO:0006282 5 0.128
meiosis i GO:0007127 59 0.125
organic substance catabolic process GO:1901575 308 0.124
cell cycle checkpoint GO:0000075 95 0.124
single organism catabolic process GO:0044712 228 0.118
ribonucleoside monophosphate catabolic process GO:0009158 39 0.117
regulation of mitotic cell cycle phase transition GO:1901990 130 0.116
protein dna complex subunit organization GO:0071824 86 0.112
cellular catabolic process GO:0044248 372 0.111
chromosome separation GO:0051304 42 0.109
ribonucleoside monophosphate metabolic process GO:0009161 51 0.107
nucleoside triphosphate catabolic process GO:0009143 108 0.104
purine nucleotide catabolic process GO:0006195 109 0.103
dna integrity checkpoint GO:0031570 81 0.103
macromolecular complex assembly GO:0065003 256 0.101
gene silencing GO:0016458 138 0.099
anatomical structure homeostasis GO:0060249 97 0.098
ribonucleotide catabolic process GO:0009261 109 0.089
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.089
eggshell chorion gene amplification GO:0007307 9 0.089
regulation of gene silencing GO:0060968 63 0.089
negative regulation of cellular biosynthetic process GO:0031327 277 0.089
regulation of double strand break repair GO:2000779 3 0.086
karyosome formation GO:0030717 22 0.085
organic cyclic compound catabolic process GO:1901361 168 0.084
nucleosome mobilization GO:0042766 9 0.084
meiotic cell cycle process GO:1903046 132 0.083
nucleoside phosphate metabolic process GO:0006753 162 0.083
cell proliferation GO:0008283 299 0.083
Worm
cellular macromolecule catabolic process GO:0044265 136 0.081
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.080
purine nucleoside monophosphate catabolic process GO:0009128 38 0.078
nucleoside triphosphate metabolic process GO:0009141 120 0.078
negative regulation of cell cycle GO:0045786 116 0.077
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.077
purine containing compound metabolic process GO:0072521 155 0.074
atp metabolic process GO:0046034 49 0.072
ribose phosphate metabolic process GO:0019693 145 0.070
oocyte fate determination GO:0030716 27 0.068
purine ribonucleoside metabolic process GO:0046128 127 0.067
transcription from rna polymerase ii promoter GO:0006366 368 0.065
ribonucleoside triphosphate catabolic process GO:0009203 108 0.065
organophosphate metabolic process GO:0019637 195 0.065
germarium derived oocyte fate determination GO:0007294 26 0.064
regulation of cell cycle GO:0051726 291 0.063
female meiotic division GO:0007143 70 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.062
regulation of dna recombination GO:0000018 4 0.061
glycosyl compound metabolic process GO:1901657 127 0.060
nuclear division GO:0000280 332 0.060
cell cycle phase transition GO:0044770 140 0.058
carbohydrate derivative catabolic process GO:1901136 118 0.056
dna endoreduplication GO:0042023 22 0.056
mitotic sister chromatid separation GO:0051306 30 0.056
purine ribonucleotide catabolic process GO:0009154 109 0.055
dorsal ventral pattern formation GO:0009953 133 0.055
catabolic process GO:0009056 409 0.055
purine nucleoside triphosphate catabolic process GO:0009146 108 0.054
protein complex assembly GO:0006461 200 0.053
purine nucleotide metabolic process GO:0006163 146 0.053
macromolecule catabolic process GO:0009057 161 0.053
telomere capping GO:0016233 11 0.053
ribonucleoside catabolic process GO:0042454 112 0.052
cellular macromolecular complex assembly GO:0034622 153 0.052
purine nucleoside catabolic process GO:0006152 112 0.051
negative regulation of mitotic cell cycle GO:0045930 109 0.050
nucleotide catabolic process GO:0009166 109 0.050
chromatin assembly GO:0031497 48 0.048
mitotic chromosome condensation GO:0007076 22 0.048
regulation of transposition GO:0010528 13 0.048
negative regulation of transcription dna templated GO:0045892 237 0.048
positive regulation of cellular biosynthetic process GO:0031328 316 0.047
Worm
programmed cell death GO:0012501 257 0.046
purine ribonucleoside catabolic process GO:0046130 112 0.046
mitotic dna replication checkpoint GO:0033314 5 0.046
nucleosome organization GO:0034728 59 0.045
nucleotide metabolic process GO:0009117 161 0.045
proteolysis GO:0006508 192 0.044
sensory organ morphogenesis GO:0090596 260 0.044
endocytosis GO:0006897 310 0.044
mitotic cell cycle phase transition GO:0044772 138 0.043
cellular response to gamma radiation GO:0071480 10 0.043
response to light stimulus GO:0009416 124 0.042
regulation of cell cycle phase transition GO:1901987 130 0.041
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.041
regulation of multicellular organismal development GO:2000026 414 0.040
resolution of meiotic recombination intermediates GO:0000712 6 0.039
intracellular signal transduction GO:0035556 300 0.039
purine nucleoside triphosphate metabolic process GO:0009144 119 0.039
embryo development ending in birth or egg hatching GO:0009792 152 0.038
Worm
response to organic substance GO:0010033 284 0.038
organonitrogen compound catabolic process GO:1901565 128 0.038
cell aging GO:0007569 2 0.036
mrna metabolic process GO:0016071 124 0.036
regulation of dna metabolic process GO:0051052 34 0.036
Worm
aging GO:0007568 143 0.036
regulation of immune system process GO:0002682 176 0.036
nucleoside metabolic process GO:0009116 127 0.036
nucleoside catabolic process GO:0009164 112 0.035
nucleobase containing small molecule metabolic process GO:0055086 174 0.035
mitotic sister chromatid segregation GO:0000070 87 0.035
protein complex biogenesis GO:0070271 201 0.035
homeostatic process GO:0042592 199 0.035
small molecule metabolic process GO:0044281 305 0.035
response to nitrogen compound GO:1901698 90 0.034
chromatin silencing GO:0006342 76 0.034
cellular protein modification process GO:0006464 438 0.033
compound eye development GO:0048749 307 0.033
purine containing compound catabolic process GO:0072523 112 0.033
regulation of cellular response to stress GO:0080135 89 0.032
phosphorylation GO:0016310 294 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
eye morphogenesis GO:0048592 260 0.032
chromatin organization GO:0006325 207 0.032
nucleoside phosphate catabolic process GO:1901292 110 0.031
vesicle mediated transport GO:0016192 381 0.031
regulation of response to dna damage stimulus GO:2001020 23 0.031
cell death GO:0008219 279 0.030
meiotic cell cycle GO:0051321 171 0.030
male pronucleus assembly GO:0035039 6 0.030
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.030
carbohydrate derivative metabolic process GO:1901135 217 0.030
protein modification process GO:0036211 438 0.029
regulation of proteolysis GO:0030162 87 0.029
immune system process GO:0002376 347 0.029
regulation of dna replication GO:0006275 13 0.029
Worm
mitotic nuclear division GO:0007067 213 0.028
transposition GO:0032196 13 0.028
ribonucleoside triphosphate metabolic process GO:0009199 119 0.027
cellular response to abiotic stimulus GO:0071214 58 0.027
response to oxygen containing compound GO:1901700 200 0.027
atp catabolic process GO:0006200 38 0.027
dna catabolic process GO:0006308 16 0.027
regulation of mitotic cell cycle GO:0007346 190 0.027
determination of adult lifespan GO:0008340 137 0.027
negative regulation of cell division GO:0051782 17 0.027
apoptotic process GO:0006915 159 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
response to other organism GO:0051707 293 0.027
replication fork processing GO:0031297 0 0.026
response to extracellular stimulus GO:0009991 116 0.026
regulation of apoptotic process GO:0042981 130 0.026
dendrite development GO:0016358 204 0.026
purine ribonucleotide metabolic process GO:0009150 145 0.026
intracellular mrna localization GO:0008298 66 0.026
ribonucleoside metabolic process GO:0009119 127 0.026
response to gamma radiation GO:0010332 17 0.025
spindle elongation GO:0051231 83 0.025
purine nucleoside monophosphate metabolic process GO:0009126 50 0.025
response to x ray GO:0010165 8 0.025
regulation of catalytic activity GO:0050790 185 0.025
negative regulation of rna metabolic process GO:0051253 251 0.025
body morphogenesis GO:0010171 2 0.025
death GO:0016265 284 0.024
metaphase anaphase transition of mitotic cell cycle GO:0007091 28 0.024
regulation of protein metabolic process GO:0051246 256 0.024
regulation of meiosis GO:0040020 3 0.024
sister chromatid segregation GO:0000819 92 0.024
regulation of chromosome organization GO:0033044 64 0.024
cell type specific apoptotic process GO:0097285 38 0.024
positive regulation of rna biosynthetic process GO:1902680 266 0.023
chromatin remodeling GO:0006338 72 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
response to uv GO:0009411 24 0.023
meiotic dna double strand break processing GO:0000706 3 0.022
centrosome organization GO:0051297 163 0.022
nucleoside monophosphate metabolic process GO:0009123 52 0.022
compound eye morphogenesis GO:0001745 249 0.021
mrna catabolic process GO:0006402 33 0.021
negative regulation of gene expression epigenetic GO:0045814 77 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
positive regulation of dna endoreduplication GO:0032877 4 0.021
response to alcohol GO:0097305 95 0.021
response to oxidative stress GO:0006979 86 0.020
regulation of response to stress GO:0080134 200 0.020
mitotic spindle stabilization GO:0043148 6 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.020
immune response GO:0006955 246 0.020
response to endogenous stimulus GO:0009719 119 0.020
regulation of transposition rna mediated GO:0010525 3 0.019
regulation of notch signaling pathway GO:0008593 100 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
negative regulation of cell communication GO:0010648 223 0.019
somatic cell dna recombination GO:0016444 1 0.019
spindle assembly involved in mitosis GO:0090307 50 0.019
response to heat GO:0009408 63 0.019
response to alkaloid GO:0043279 26 0.019
regulation of immune response GO:0050776 118 0.019
protein phosphorylation GO:0006468 169 0.018
response to organonitrogen compound GO:0010243 75 0.018
regulation of mitotic recombination GO:0000019 1 0.018
response to lipopolysaccharide GO:0032496 4 0.018
regulation of programmed cell death GO:0043067 152 0.018
chromatin assembly or disassembly GO:0006333 52 0.018
multicellular organism growth GO:0035264 46 0.018
regulation of phosphate metabolic process GO:0019220 210 0.018
positive regulation of gene expression GO:0010628 290 0.018
dna replication checkpoint GO:0000076 8 0.018
negative regulation of meiotic cell cycle GO:0051447 2 0.018
positive regulation of programmed cell death GO:0043068 62 0.017
mitotic sister chromatid cohesion GO:0007064 6 0.017
regulation of cell death GO:0010941 173 0.017
histone lysine demethylation GO:0070076 6 0.017
regulation of cell division GO:0051302 72 0.017
protein maturation GO:0051604 71 0.017
response to camptothecin GO:1901563 2 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
spindle assembly GO:0051225 80 0.017
glycosyl compound catabolic process GO:1901658 112 0.017
retrograde axon cargo transport GO:0008090 9 0.017
negative regulation of gene expression GO:0010629 387 0.016
positive regulation of response to stimulus GO:0048584 323 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
Worm
polarity specification of anterior posterior axis GO:0009949 5 0.016
regulation of mitotic sister chromatid separation GO:0010965 28 0.015
eye photoreceptor cell differentiation GO:0001754 145 0.015
protein alkylation GO:0008213 43 0.015
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.015
g2 m transition of mitotic cell cycle GO:0000086 19 0.015
immune system development GO:0002520 57 0.015
respiratory system development GO:0060541 213 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
regulation of cell cycle process GO:0010564 181 0.015
organophosphate catabolic process GO:0046434 112 0.015
regulation of protein dephosphorylation GO:0035304 5 0.014
multicellular organismal aging GO:0010259 140 0.014
mitotic spindle assembly checkpoint GO:0007094 11 0.014
positive regulation of cellular protein metabolic process GO:0032270 118 0.014
regulation of dna dependent dna replication GO:0090329 6 0.014
notch signaling pathway GO:0007219 120 0.014
cell division GO:0051301 248 0.014
growth GO:0040007 359 0.014
positive regulation of molecular function GO:0044093 136 0.014
nucleoside monophosphate catabolic process GO:0009125 39 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
regulation of nucleotide catabolic process GO:0030811 48 0.014
specification of axis polarity GO:0065001 6 0.014
dna catabolic process exonucleolytic GO:0000738 8 0.014
cell cycle comprising mitosis without cytokinesis GO:0033301 25 0.013
epithelial cell differentiation GO:0030855 322 0.013
regulation of nervous system development GO:0051960 248 0.013
cellular response to organic substance GO:0071310 132 0.013
cellular response to organonitrogen compound GO:0071417 36 0.013
mitotic cell cycle embryonic GO:0045448 38 0.013
imaginal disc derived appendage morphogenesis GO:0035114 395 0.013
mrna processing GO:0006397 104 0.013
cell cycle arrest GO:0007050 4 0.013
enzyme linked receptor protein signaling pathway GO:0007167 179 0.013
endomembrane system organization GO:0010256 119 0.012
immune response regulating signaling pathway GO:0002764 2 0.012
regulation of phosphorylation GO:0042325 147 0.012
open tracheal system development GO:0007424 204 0.012
negative regulation of notch signaling pathway GO:0045746 41 0.012
cell fate determination GO:0001709 91 0.012
connective tissue development GO:0061448 3 0.012
negative regulation of rna biosynthetic process GO:1902679 240 0.012
positive regulation of g2 m transition of mitotic cell cycle GO:0010971 2 0.012
regulation of phosphatidylinositol 3 kinase activity GO:0043551 2 0.012
establishment of localization in cell GO:0051649 402 0.012
spindle organization GO:0007051 253 0.012
appendage morphogenesis GO:0035107 397 0.011
generation of precursor metabolites and energy GO:0006091 42 0.011
regulation of histone deacetylation GO:0031063 2 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.011
regulation of molecular function GO:0065009 217 0.011
negative regulation of signaling GO:0023057 219 0.011
intra s dna damage checkpoint GO:0031573 2 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
regulation of smoothened signaling pathway GO:0008589 28 0.011
positive regulation of nervous system development GO:0051962 69 0.011
distributive segregation GO:0032837 6 0.011
negative regulation of mitotic sister chromatid separation GO:2000816 13 0.011
single organism behavior GO:0044708 391 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
regulation of mitosis GO:0007088 56 0.011
regulation of defense response GO:0031347 102 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
posttranscriptional gene silencing by rna GO:0035194 45 0.011
response to nutrient levels GO:0031667 114 0.011
regulation of mitotic spindle elongation GO:0032888 1 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
regulation of double strand break repair via homologous recombination GO:0010569 2 0.010
neuron remodeling GO:0016322 29 0.010
rna catabolic process GO:0006401 37 0.010
positive regulation of cellular catabolic process GO:0031331 95 0.010
positive regulation of cell communication GO:0010647 250 0.010
larval development GO:0002164 104 0.010
atp dependent chromatin remodeling GO:0043044 22 0.010
carboxylic acid metabolic process GO:0019752 92 0.010
regulation of cellular response to oxidative stress GO:1900407 4 0.010
regulation of cellular catabolic process GO:0031329 157 0.010
heterochromatin organization GO:0070828 25 0.010
regulation of protein catabolic process GO:0042176 55 0.010

mus101 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
thoracic cancer DOID:5093 0 0.100
cancer DOID:162 0 0.100
disease of cellular proliferation DOID:14566 0 0.100
organ system cancer DOID:0050686 0 0.100
musculoskeletal system cancer DOID:0060100 0 0.074
connective tissue cancer DOID:201 0 0.074
breast cancer DOID:1612 0 0.059
disease of anatomical entity DOID:7 0 0.016
nervous system disease DOID:863 0 0.016