Drosophila melanogaster

0 known processes

Mlh1 (Dmel_CG11482)

CG11482 gene product from transcript CG11482-RA

(Aliases: Dmel\CG11482,CG11482,dmlh1,dmlh-1)

Mlh1 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna metabolic process GO:0006259 227 0.765
Mouse
dna repair GO:0006281 54 0.550
Mouse
cellular response to dna damage stimulus GO:0006974 223 0.283
Mouse
protein complex biogenesis GO:0070271 201 0.132
Mouse
dna replication GO:0006260 48 0.128
chromatin assembly GO:0031497 48 0.100
double strand break repair GO:0006302 26 0.092
Mouse
protein complex assembly GO:0006461 200 0.082
Mouse
cellular protein modification process GO:0006464 438 0.080
macromolecular complex assembly GO:0065003 256 0.077
Mouse
dna recombination GO:0006310 32 0.074
Mouse
sister chromatid segregation GO:0000819 92 0.074
telomere organization GO:0032200 21 0.067
meiosis i GO:0007127 59 0.058
Mouse
chromosome segregation GO:0007059 157 0.054
Mouse
dna biosynthetic process GO:0071897 24 0.051
regulation of cell cycle GO:0051726 291 0.049
dna packaging GO:0006323 91 0.048
protein modification process GO:0036211 438 0.048
organic substance catabolic process GO:1901575 308 0.044
Mouse
chromosome organization GO:0051276 360 0.038
Mouse
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.035
cellular macromolecule catabolic process GO:0044265 136 0.034
Mouse
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.033
regulation of mitotic cell cycle GO:0007346 190 0.032
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.031
nuclear division GO:0000280 332 0.030
Mouse
positive regulation of gene expression GO:0010628 290 0.030
tube development GO:0035295 244 0.030
chromatin modification GO:0016568 147 0.029
positive regulation of cellular biosynthetic process GO:0031328 316 0.029
mitotic nuclear division GO:0007067 213 0.028
response to fungus GO:0009620 50 0.027
mitotic sister chromatid segregation GO:0000070 87 0.027
catabolic process GO:0009056 409 0.027
Mouse
positive regulation of biosynthetic process GO:0009891 316 0.026
establishment of organelle localization GO:0051656 122 0.025
Mouse
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.024
Mouse
positive regulation of cellular component organization GO:0051130 156 0.024
chromatin organization GO:0006325 207 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
purine nucleoside metabolic process GO:0042278 127 0.023
cellular component assembly involved in morphogenesis GO:0010927 151 0.023
purine containing compound catabolic process GO:0072523 112 0.023
negative regulation of signaling GO:0023057 219 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.021
regulation of molecular function GO:0065009 217 0.021
tube morphogenesis GO:0035239 191 0.021
cellular macromolecule localization GO:0070727 220 0.021
cellular nitrogen compound catabolic process GO:0044270 165 0.020
Mouse
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
compound eye development GO:0048749 307 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
heterocycle catabolic process GO:0046700 166 0.020
Mouse
aromatic compound catabolic process GO:0019439 166 0.020
Mouse
positive regulation of macromolecule metabolic process GO:0010604 405 0.020
double strand break repair via nonhomologous end joining GO:0006303 5 0.020
Mouse
mitotic spindle elongation GO:0000022 81 0.020
regulation of cellular protein metabolic process GO:0032268 243 0.019
morphogenesis of an epithelium GO:0002009 276 0.019
growth GO:0040007 359 0.019
single organism membrane organization GO:0044802 93 0.019
organelle assembly GO:0070925 198 0.019
Mouse
response to biotic stimulus GO:0009607 294 0.019
actin cytoskeleton organization GO:0030036 206 0.019
cellular response to endogenous stimulus GO:0071495 80 0.019
cardiovascular system development GO:0072358 82 0.019
notch signaling pathway GO:0007219 120 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.019
Mouse
ribonucleoside metabolic process GO:0009119 127 0.019
regionalization GO:0003002 416 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.018
endocytosis GO:0006897 310 0.018
cellular amine metabolic process GO:0044106 12 0.018
organonitrogen compound metabolic process GO:1901564 318 0.018
positive regulation of transcription dna templated GO:0045893 266 0.018
mitotic spindle organization GO:0007052 220 0.018
nucleoside monophosphate metabolic process GO:0009123 52 0.018
regulation of dna metabolic process GO:0051052 34 0.018
Mouse
regulation of organelle organization GO:0033043 196 0.017
meiotic chromosome segregation GO:0045132 59 0.017
Mouse
immune system process GO:0002376 347 0.017
Mouse
cell division GO:0051301 248 0.017
telomere maintenance GO:0000723 21 0.017
anatomical structure homeostasis GO:0060249 97 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
enzyme linked receptor protein signaling pathway GO:0007167 179 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
homeostatic process GO:0042592 199 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
embryo development ending in birth or egg hatching GO:0009792 152 0.015
meiotic cell cycle process GO:1903046 132 0.015
Mouse
vesicle mediated transport GO:0016192 381 0.014
death GO:0016265 284 0.014
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.014
Mouse
dna integrity checkpoint GO:0031570 81 0.014
imaginal disc derived appendage development GO:0048737 399 0.014
camera type eye development GO:0043010 4 0.014
peptidyl amino acid modification GO:0018193 105 0.014
gland morphogenesis GO:0022612 145 0.014
carbohydrate derivative metabolic process GO:1901135 217 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
Mouse
nucleoside phosphate metabolic process GO:0006753 162 0.014
positive regulation of rna metabolic process GO:0051254 271 0.014
membrane organization GO:0061024 112 0.014
protein localization GO:0008104 284 0.014
post embryonic appendage morphogenesis GO:0035120 385 0.014
purine ribonucleoside metabolic process GO:0046128 127 0.014
nucleoside triphosphate catabolic process GO:0009143 108 0.013
cell proliferation GO:0008283 299 0.013
actin filament based process GO:0030029 220 0.013
negative regulation of cell communication GO:0010648 223 0.013
cellular ketone metabolic process GO:0042180 24 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
organelle fission GO:0048285 340 0.013
Mouse
regulation of cell differentiation GO:0045595 302 0.013
negative regulation of nucleic acid templated transcription GO:1903507 240 0.013
regulation of actin cytoskeleton organization GO:0032956 42 0.013
aging GO:0007568 143 0.013
cellular catabolic process GO:0044248 372 0.013
Mouse
endomembrane system organization GO:0010256 119 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
nucleus organization GO:0006997 45 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
phagocytosis GO:0006909 215 0.012
amine metabolic process GO:0009308 12 0.012
mitotic dna integrity checkpoint GO:0044774 75 0.012
mitotic dna damage checkpoint GO:0044773 74 0.012
circulatory system development GO:0072359 82 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
negative regulation of response to stimulus GO:0048585 258 0.012
oxoacid metabolic process GO:0043436 103 0.012
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
dna conformation change GO:0071103 105 0.012
positive regulation of molecular function GO:0044093 136 0.012
protein phosphorylation GO:0006468 169 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
meiotic nuclear division GO:0007126 151 0.011
Mouse
nucleoside catabolic process GO:0009164 112 0.011
chromatin remodeling GO:0006338 72 0.011
small molecule metabolic process GO:0044281 305 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
phosphorylation GO:0016310 294 0.011
single organism cellular localization GO:1902580 180 0.011
ameboidal type cell migration GO:0001667 151 0.011
cellular response to organic substance GO:0071310 132 0.011
macromolecule catabolic process GO:0009057 161 0.011
Mouse
cell fate determination GO:0001709 91 0.011
regulation of notch signaling pathway GO:0008593 100 0.011
recombinational repair GO:0000725 13 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
negative regulation of gene expression epigenetic GO:0045814 77 0.011
nucleotide catabolic process GO:0009166 109 0.010
establishment of protein localization GO:0045184 163 0.010
cellular protein complex assembly GO:0043623 71 0.010
Mouse
rhabdomere development GO:0042052 38 0.010
positive regulation of cellular amine metabolic process GO:0033240 0 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
response to oxygen containing compound GO:1901700 200 0.010
body morphogenesis GO:0010171 2 0.010

Mlh1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018