Drosophila melanogaster

45 known processes

Eip63E (Dmel_CG10579)

Ecdysone-induced protein 63E

(Aliases: Dmel\CG10579,CG10579,cdc2-63E,PFTAIRE,L63)

Eip63E biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.815
negative regulation of rna metabolic process GO:0051253 251 0.795
nucleobase containing compound catabolic process GO:0034655 165 0.702
growth GO:0040007 359 0.652
heterocycle catabolic process GO:0046700 166 0.645
dna damage checkpoint GO:0000077 78 0.575
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.500
chromosome organization GO:0051276 360 0.487
single organism catabolic process GO:0044712 228 0.476
nucleoside triphosphate catabolic process GO:0009143 108 0.436
negative regulation of biosynthetic process GO:0009890 277 0.433
transcription from rna polymerase ii promoter GO:0006366 368 0.432
cell cycle dna replication GO:0044786 23 0.428
aromatic compound catabolic process GO:0019439 166 0.411
negative regulation of cellular metabolic process GO:0031324 382 0.394
ribonucleoside triphosphate catabolic process GO:0009203 108 0.384
positive regulation of gene expression GO:0010628 290 0.375
nucleoside metabolic process GO:0009116 127 0.371
positive regulation of nucleic acid templated transcription GO:1903508 266 0.370
positive regulation of transcription dna templated GO:0045893 266 0.365
cellular nitrogen compound catabolic process GO:0044270 165 0.361
dna metabolic process GO:0006259 227 0.359
appendage morphogenesis GO:0035107 397 0.353
purine nucleoside triphosphate catabolic process GO:0009146 108 0.328
positive regulation of biosynthetic process GO:0009891 316 0.317
positive regulation of rna metabolic process GO:0051254 271 0.315
purine nucleoside catabolic process GO:0006152 112 0.308
positive regulation of cellular biosynthetic process GO:0031328 316 0.297
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.284
organic substance catabolic process GO:1901575 308 0.283
negative regulation of rna biosynthetic process GO:1902679 240 0.281
small gtpase mediated signal transduction GO:0007264 88 0.275
positive regulation of rna biosynthetic process GO:1902680 266 0.267
negative regulation of response to stimulus GO:0048585 258 0.263
regulation of multicellular organism growth GO:0040014 40 0.261
positive regulation of multicellular organismal process GO:0051240 143 0.256
nucleoside catabolic process GO:0009164 112 0.249
negative regulation of nucleic acid templated transcription GO:1903507 240 0.248
cellular response to abiotic stimulus GO:0071214 58 0.247
nucleotide catabolic process GO:0009166 109 0.235
negative regulation of signal transduction GO:0009968 206 0.231
regulation of developmental growth GO:0048638 174 0.225
ribonucleoside triphosphate metabolic process GO:0009199 119 0.224
protein complex biogenesis GO:0070271 201 0.223
chromatin organization GO:0006325 207 0.219
ribonucleoside metabolic process GO:0009119 127 0.216
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.216
imaginal disc derived appendage development GO:0048737 399 0.214
multicellular organism growth GO:0035264 46 0.204
negative regulation of signaling GO:0023057 219 0.201
organic cyclic compound catabolic process GO:1901361 168 0.197
dna integrity checkpoint GO:0031570 81 0.191
positive regulation of signaling GO:0023056 243 0.190
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.190
purine containing compound catabolic process GO:0072523 112 0.188
organonitrogen compound catabolic process GO:1901565 128 0.185
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.183
developmental growth GO:0048589 280 0.180
positive regulation of signal transduction GO:0009967 223 0.177
purine ribonucleoside metabolic process GO:0046128 127 0.176
guanosine containing compound metabolic process GO:1901068 74 0.174
purine nucleotide catabolic process GO:0006195 109 0.172
negative regulation of cellular biosynthetic process GO:0031327 277 0.172
negative regulation of gene expression GO:0010629 387 0.161
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.159
regulation of growth GO:0040008 233 0.157
ras protein signal transduction GO:0007265 88 0.156
purine nucleoside triphosphate metabolic process GO:0009144 119 0.156
catabolic process GO:0009056 409 0.155
ribonucleoside catabolic process GO:0042454 112 0.152
purine nucleotide metabolic process GO:0006163 146 0.152
ribonucleotide metabolic process GO:0009259 145 0.151
regulation of cell death GO:0010941 173 0.147
negative regulation of transcription dna templated GO:0045892 237 0.143
mitochondrion organization GO:0007005 65 0.142
purine ribonucleoside catabolic process GO:0046130 112 0.140
purine nucleoside metabolic process GO:0042278 127 0.138
positive regulation of developmental growth GO:0048639 62 0.136
cellular catabolic process GO:0044248 372 0.136
mitotic dna damage checkpoint GO:0044773 74 0.135
cellular response to radiation GO:0071478 52 0.135
response to extracellular stimulus GO:0009991 116 0.134
glycosyl compound catabolic process GO:1901658 112 0.132
regulation of small gtpase mediated signal transduction GO:0051056 93 0.132
appendage development GO:0048736 401 0.131
glycosyl compound metabolic process GO:1901657 127 0.130
positive regulation of cell communication GO:0010647 250 0.127
gtp metabolic process GO:0046039 72 0.126
regulation of ras protein signal transduction GO:0046578 93 0.124
leg disc development GO:0035218 92 0.124
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.123
nucleobase containing small molecule metabolic process GO:0055086 174 0.121
covalent chromatin modification GO:0016569 106 0.121
death GO:0016265 284 0.120
gtp catabolic process GO:0006184 72 0.120
post embryonic appendage morphogenesis GO:0035120 385 0.120
guanosine containing compound catabolic process GO:1901069 74 0.118
posttranscriptional gene silencing by rna GO:0035194 45 0.118
mitotic g2 m transition checkpoint GO:0044818 70 0.117
establishment of localization in cell GO:0051649 402 0.115
small molecule metabolic process GO:0044281 305 0.113
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.112
intracellular signal transduction GO:0035556 300 0.110
regulation of dna metabolic process GO:0051052 34 0.110
regulation of cell proliferation GO:0042127 163 0.110
nucleoside phosphate catabolic process GO:1901292 110 0.107
negative regulation of cell cycle GO:0045786 116 0.104
meiotic cell cycle process GO:1903046 132 0.100
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.098
segmentation GO:0035282 207 0.098
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.097
intracellular transport GO:0046907 228 0.096
nucleotide metabolic process GO:0009117 161 0.090
regulation of intracellular signal transduction GO:1902531 236 0.088
purine ribonucleotide catabolic process GO:0009154 109 0.086
cellular macromolecule catabolic process GO:0044265 136 0.086
purine ribonucleotide metabolic process GO:0009150 145 0.085
nucleoside phosphate metabolic process GO:0006753 162 0.082
dna replication GO:0006260 48 0.078
positive regulation of macromolecule metabolic process GO:0010604 405 0.076
cell cycle checkpoint GO:0000075 95 0.075
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.073
pigmentation GO:0043473 75 0.073
nuclear division GO:0000280 332 0.072
ribose phosphate metabolic process GO:0019693 145 0.072
positive regulation of growth GO:0045927 75 0.071
cellular response to chemical stimulus GO:0070887 199 0.071
organophosphate catabolic process GO:0046434 112 0.069
regulation of programmed cell death GO:0043067 152 0.068
positive regulation of developmental process GO:0051094 143 0.067
actin filament based process GO:0030029 220 0.067
nucleoside triphosphate metabolic process GO:0009141 120 0.067
carbohydrate derivative metabolic process GO:1901135 217 0.066
positive regulation of multicellular organism growth GO:0040018 21 0.065
response to organic substance GO:0010033 284 0.063
regulation of multicellular organismal development GO:2000026 414 0.063
syncytium formation GO:0006949 43 0.062
carbohydrate derivative catabolic process GO:1901136 118 0.059
regulation of neural precursor cell proliferation GO:2000177 35 0.059
tube morphogenesis GO:0035239 191 0.058
cell proliferation GO:0008283 299 0.058
response to nutrient levels GO:0031667 114 0.057
organophosphate metabolic process GO:0019637 195 0.056
glycerolipid metabolic process GO:0046486 34 0.056
positive regulation of cell proliferation GO:0008284 47 0.055
regulation of purine nucleotide catabolic process GO:0033121 48 0.055
regulation of immune system process GO:0002682 176 0.054
immune response GO:0006955 246 0.054
heterochromatin organization GO:0070828 25 0.052
positive regulation of response to stimulus GO:0048584 323 0.052
regulation of gene expression epigenetic GO:0040029 128 0.051
body morphogenesis GO:0010171 2 0.050
mitotic g2 dna damage checkpoint GO:0007095 69 0.050
dna conformation change GO:0071103 105 0.049
single organism biosynthetic process GO:0044711 206 0.049
cell aging GO:0007569 2 0.047
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.047
chromatin modification GO:0016568 147 0.047
response to oxygen levels GO:0070482 59 0.045
establishment or maintenance of cell polarity GO:0007163 167 0.045
lipid catabolic process GO:0016042 21 0.041
immune response regulating signaling pathway GO:0002764 2 0.041
positive regulation of phosphorus metabolic process GO:0010562 139 0.041
blastoderm segmentation GO:0007350 159 0.041
cellular response to sterol depletion GO:0071501 3 0.041
negative regulation of cell cycle process GO:0010948 109 0.041
regulation of phosphorylation GO:0042325 147 0.040
posttranscriptional regulation of gene expression GO:0010608 145 0.039
actin cytoskeleton organization GO:0030036 206 0.038
positive regulation of phosphate metabolic process GO:0045937 139 0.038
cell death GO:0008219 279 0.037
regulation of localization GO:0032879 275 0.036
posttranscriptional gene silencing GO:0016441 46 0.036
organic acid metabolic process GO:0006082 103 0.036
organonitrogen compound metabolic process GO:1901564 318 0.035
eggshell chorion assembly GO:0007306 66 0.035
regulation of catabolic process GO:0009894 170 0.035
leg disc morphogenesis GO:0007478 80 0.035
regulation of cellular protein metabolic process GO:0032268 243 0.035
regulation of nucleotide catabolic process GO:0030811 48 0.034
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090101 18 0.034
rac protein signal transduction GO:0016601 3 0.034
mitotic dna integrity checkpoint GO:0044774 75 0.033
immune response activating signal transduction GO:0002757 2 0.033
programmed cell death GO:0012501 257 0.033
negative regulation of cell communication GO:0010648 223 0.032
steroid biosynthetic process GO:0006694 16 0.032
response to oxygen containing compound GO:1901700 200 0.032
gene silencing GO:0016458 138 0.032
pupal development GO:0035209 11 0.031
response to temperature stimulus GO:0009266 106 0.031
purine containing compound metabolic process GO:0072521 155 0.031
myoblast fusion GO:0007520 43 0.031
response to organonitrogen compound GO:0010243 75 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.030
negative regulation of cellular protein metabolic process GO:0032269 85 0.030
negative regulation of apoptotic process GO:0043066 63 0.029
larval development GO:0002164 104 0.029
regulation of mitotic cell cycle phase transition GO:1901990 130 0.029
regulation of ras gtpase activity GO:0032318 38 0.029
positive regulation of cellular catabolic process GO:0031331 95 0.028
ribonucleoside monophosphate catabolic process GO:0009158 39 0.028
negative regulation of ras protein signal transduction GO:0046580 13 0.028
regulation of catalytic activity GO:0050790 185 0.027
spindle organization GO:0007051 253 0.027
imaginal disc derived leg morphogenesis GO:0007480 80 0.027
immune system process GO:0002376 347 0.026
determination of dorsal ventral asymmetry GO:0048262 3 0.026
chromatin silencing GO:0006342 76 0.025
mitotic cell cycle checkpoint GO:0007093 88 0.025
mitotic nuclear division GO:0007067 213 0.025
retinal cell programmed cell death GO:0046666 25 0.025
macromolecule catabolic process GO:0009057 161 0.024
ribonucleoprotein complex subunit organization GO:0071826 28 0.024
regulation of cellular catabolic process GO:0031329 157 0.024
wing disc morphogenesis GO:0007472 344 0.024
anatomical structure homeostasis GO:0060249 97 0.024
phagocytosis GO:0006909 215 0.024
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.023
wnt signaling pathway GO:0016055 98 0.023
Human
cellular carbohydrate metabolic process GO:0044262 22 0.023
positive regulation of nucleotide metabolic process GO:0045981 55 0.022
response to abiotic stimulus GO:0009628 341 0.022
regulation of response to dna damage stimulus GO:2001020 23 0.022
jak stat cascade GO:0007259 49 0.021
response to organic cyclic compound GO:0014070 89 0.021
cellular response to dna damage stimulus GO:0006974 223 0.021
regulation of mitotic cell cycle GO:0007346 190 0.021
positive regulation of cell motility GO:2000147 3 0.021
rna processing GO:0006396 147 0.021
establishment of cell polarity GO:0030010 40 0.021
notch signaling pathway GO:0007219 120 0.021
regulation of protein phosphorylation GO:0001932 64 0.021
nuclear dna replication GO:0033260 1 0.021
hemocyte differentiation GO:0042386 38 0.020
positive regulation of cell size GO:0045793 21 0.020
oxoacid metabolic process GO:0043436 103 0.020
macroautophagy GO:0016236 42 0.020
positive regulation of intracellular signal transduction GO:1902533 116 0.019
generation of precursor metabolites and energy GO:0006091 42 0.019
histone h4 acetylation GO:0043967 13 0.019
single organism intracellular transport GO:1902582 207 0.019
aging GO:0007568 143 0.019
tube development GO:0035295 244 0.019
regulation of gtp catabolic process GO:0033124 44 0.019
pronuclear migration GO:0035046 4 0.019
positive regulation of cell migration GO:0030335 2 0.019
regulation of cellular response to stress GO:0080135 89 0.019
response to decreased oxygen levels GO:0036293 58 0.019
endomitotic cell cycle GO:0007113 7 0.019
nucleocytoplasmic transport GO:0006913 72 0.019
protein phosphorylation GO:0006468 169 0.019
retina development in camera type eye GO:0060041 4 0.018
regulation of gtpase activity GO:0043087 44 0.018
protein catabolic process GO:0030163 101 0.018
phosphorylation GO:0016310 294 0.018
cellular protein modification process GO:0006464 438 0.018
deactivation of rhodopsin mediated signaling GO:0016059 17 0.018
regulation of apoptotic process GO:0042981 130 0.018
meiosis i GO:0007127 59 0.018
er nucleus signaling pathway GO:0006984 9 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
inositol lipid mediated signaling GO:0048017 4 0.017
regulation of notch signaling pathway GO:0008593 100 0.017
regulation of nervous system development GO:0051960 248 0.017
regulation of immune response GO:0050776 118 0.017
regulation of defense response GO:0031347 102 0.017
ribonucleotide catabolic process GO:0009261 109 0.017
histone modification GO:0016570 106 0.017
mushroom body development GO:0016319 70 0.016
cellular response to extracellular stimulus GO:0031668 64 0.016
forebrain development GO:0030900 2 0.016
fertilization GO:0009566 26 0.016
negative regulation of cell cycle phase transition GO:1901988 103 0.016
protein targeting to nucleus GO:0044744 51 0.016
homeostatic process GO:0042592 199 0.016
vesicle mediated transport GO:0016192 381 0.016
regulation of nucleotide metabolic process GO:0006140 62 0.016
positive regulation of protein phosphorylation GO:0001934 34 0.016
organelle assembly GO:0070925 198 0.016
regulation of cell cycle GO:0051726 291 0.016
rna 3 end processing GO:0031123 45 0.016
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.016
neuromuscular junction development GO:0007528 149 0.015
activation of innate immune response GO:0002218 4 0.015
regulation of heterochromatin assembly GO:0031445 8 0.015
regulation of sister chromatid cohesion GO:0007063 2 0.015
regulation of proteolysis GO:0030162 87 0.015
cellular response to external stimulus GO:0071496 66 0.015
purine nucleoside monophosphate catabolic process GO:0009128 38 0.015
regulation of cellular component movement GO:0051270 42 0.015
negative regulation of immune system process GO:0002683 50 0.015
nucleobase containing compound transport GO:0015931 56 0.015
negative regulation of gene expression epigenetic GO:0045814 77 0.015
actin filament organization GO:0007015 126 0.014
ameboidal type cell migration GO:0001667 151 0.014
lamellipodium organization GO:0097581 21 0.014
gene silencing by rna GO:0031047 57 0.014
response to monosaccharide GO:0034284 4 0.014
regulation of protein metabolic process GO:0051246 256 0.014
positive regulation of protein complex assembly GO:0031334 22 0.014
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
establishment of organelle localization GO:0051656 122 0.014
developmental pigmentation GO:0048066 68 0.014
response to alcohol GO:0097305 95 0.014
cellular amino acid metabolic process GO:0006520 61 0.014
positive regulation of nurse cell apoptotic process GO:0045850 5 0.014
negative regulation of intracellular signal transduction GO:1902532 57 0.014
regulation of hydrolase activity GO:0051336 97 0.014
meiotic cell cycle GO:0051321 171 0.013
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
regulation of cellular amino acid metabolic process GO:0006521 0 0.013
apoptotic process GO:0006915 159 0.013
regulation of hemocyte differentiation GO:0045610 22 0.013
muscle structure development GO:0061061 224 0.013
synaptic growth at neuromuscular junction GO:0051124 119 0.013
ecdysone receptor mediated signaling pathway GO:0035076 11 0.013
regulation of cell motility GO:2000145 23 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
positive regulation of phosphorylation GO:0042327 87 0.013
actin filament polymerization GO:0030041 27 0.012
regulation of transport GO:0051049 181 0.012
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.012
regulation of organelle organization GO:0033043 196 0.012
organelle fusion GO:0048284 46 0.012
glandular epithelial cell differentiation GO:0002067 1 0.012
developmental programmed cell death GO:0010623 138 0.012
cognition GO:0050890 141 0.012
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.012
regulation of cellular localization GO:0060341 136 0.012
endocytosis GO:0006897 310 0.012
myotube cell development GO:0014904 3 0.012
myotube differentiation GO:0014902 46 0.012
regulation of cell differentiation GO:0045595 302 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
regulation of protein modification process GO:0031399 112 0.012
regulation of rac protein signal transduction GO:0035020 3 0.012
cellular response to starvation GO:0009267 61 0.012
salivary gland histolysis GO:0035070 88 0.012
chromatin assembly GO:0031497 48 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
cellular ketone metabolic process GO:0042180 24 0.011
regulation of neuron differentiation GO:0045664 103 0.011
regulation of cellular component biogenesis GO:0044087 201 0.011
chorion containing eggshell pattern formation GO:0030381 11 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
positive regulation of lipid catabolic process GO:0050996 1 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
regulation of nucleoside metabolic process GO:0009118 50 0.011
positive regulation of feeding behavior GO:2000253 8 0.011
positive regulation of cell development GO:0010720 61 0.011
innate immune response GO:0045087 144 0.011
regulation of phosphatase activity GO:0010921 3 0.011
rho protein signal transduction GO:0007266 14 0.011
mitotic sister chromatid segregation GO:0000070 87 0.011
regulation of molecular function GO:0065009 217 0.011
locomotory behavior GO:0007626 176 0.011
salivary gland development GO:0007431 162 0.011
compound eye retinal cell programmed cell death GO:0046667 23 0.011
cellular response to nutrient levels GO:0031669 62 0.011
camera type eye morphogenesis GO:0048593 2 0.011
cell cycle arrest GO:0007050 4 0.011
camera type eye development GO:0043010 4 0.011
neutral lipid metabolic process GO:0006638 12 0.011
immune system development GO:0002520 57 0.011
positive regulation of gtp catabolic process GO:0033126 43 0.011
atp catabolic process GO:0006200 38 0.011
response to lipid GO:0033993 38 0.011
cytoplasmic transport GO:0016482 130 0.011
chromosome segregation GO:0007059 157 0.011
imaginal disc derived wing morphogenesis GO:0007476 337 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
skeletal muscle fiber development GO:0048741 3 0.010
positive regulation of cell death GO:0010942 69 0.010
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
nucleoside monophosphate catabolic process GO:0009125 39 0.010
regulation of transferase activity GO:0051338 58 0.010
nucleosome mobilization GO:0042766 9 0.010
nuclear transport GO:0051169 72 0.010
nuclear import GO:0051170 51 0.010
development of primary sexual characteristics GO:0045137 50 0.010
meiotic nuclear division GO:0007126 151 0.010
gland development GO:0048732 191 0.010

Eip63E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
cancer DOID:162 0 0.015
disease of cellular proliferation DOID:14566 0 0.015
organ system cancer DOID:0050686 0 0.015