Drosophila melanogaster

0 known processes

HERC2 (Dmel_CG11734)

CG11734 gene product from transcript CG11734-RC

(Aliases: CG11734,Dmel\CG11734)

HERC2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
imaginal disc derived appendage morphogenesis GO:0035114 395 0.181
post embryonic appendage morphogenesis GO:0035120 385 0.138
appendage morphogenesis GO:0035107 397 0.105
imaginal disc derived appendage development GO:0048737 399 0.104
actin filament based process GO:0030029 220 0.101
imaginal disc derived wing morphogenesis GO:0007476 337 0.096
wing disc morphogenesis GO:0007472 344 0.091
organelle localization GO:0051640 148 0.087
negative regulation of cellular metabolic process GO:0031324 382 0.085
single organism behavior GO:0044708 391 0.085
vesicle mediated transport GO:0016192 381 0.081
organophosphate metabolic process GO:0019637 195 0.079
lateral inhibition GO:0046331 206 0.077
establishment of localization in cell GO:0051649 402 0.072
synaptic transmission GO:0007268 288 0.070
regulation of multicellular organismal development GO:2000026 414 0.069
establishment of organelle localization GO:0051656 122 0.069
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.062
chromosome organization GO:0051276 360 0.061
developmental maturation GO:0021700 172 0.060
purine containing compound metabolic process GO:0072521 155 0.059
tissue morphogenesis GO:0048729 297 0.055
morphogenesis of an epithelium GO:0002009 276 0.055
negative regulation of signaling GO:0023057 219 0.054
ribonucleoside triphosphate catabolic process GO:0009203 108 0.054
nuclear division GO:0000280 332 0.051
nucleobase containing small molecule metabolic process GO:0055086 174 0.051
organonitrogen compound metabolic process GO:1901564 318 0.049
nucleoside phosphate metabolic process GO:0006753 162 0.049
organonitrogen compound biosynthetic process GO:1901566 117 0.047
small molecule metabolic process GO:0044281 305 0.047
synapse organization GO:0050808 196 0.047
catabolic process GO:0009056 409 0.046
organelle fission GO:0048285 340 0.045
response to abiotic stimulus GO:0009628 341 0.045
defense response GO:0006952 300 0.045
small gtpase mediated signal transduction GO:0007264 88 0.044
organic substance catabolic process GO:1901575 308 0.042
regulation of molecular function GO:0065009 217 0.042
compound eye development GO:0048749 307 0.041
regulation of cell differentiation GO:0045595 302 0.041
purine nucleotide metabolic process GO:0006163 146 0.041
cellular catabolic process GO:0044248 372 0.041
protein localization GO:0008104 284 0.041
negative regulation of transcription dna templated GO:0045892 237 0.040
compound eye photoreceptor cell differentiation GO:0001751 140 0.040
ribonucleotide metabolic process GO:0009259 145 0.040
ribose phosphate metabolic process GO:0019693 145 0.039
embryonic morphogenesis GO:0048598 206 0.039
actin cytoskeleton organization GO:0030036 206 0.039
actin filament organization GO:0007015 126 0.039
cell cell signaling involved in cell fate commitment GO:0045168 210 0.039
regulation of organelle organization GO:0033043 196 0.039
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.038
regionalization GO:0003002 416 0.038
nucleotide metabolic process GO:0009117 161 0.037
photoreceptor cell differentiation GO:0046530 170 0.037
positive regulation of biosynthetic process GO:0009891 316 0.037
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.037
establishment of synaptic vesicle localization GO:0097480 50 0.037
synaptic vesicle localization GO:0097479 53 0.036
regulation of phosphorus metabolic process GO:0051174 210 0.036
single organism membrane organization GO:0044802 93 0.036
gene silencing GO:0016458 138 0.036
negative regulation of cell communication GO:0010648 223 0.035
negative regulation of cellular biosynthetic process GO:0031327 277 0.035
organic substance transport GO:0071702 257 0.035
regulation of cellular component biogenesis GO:0044087 201 0.034
regulation of cytoskeleton organization GO:0051493 89 0.033
axonogenesis GO:0007409 290 0.033
homeostatic process GO:0042592 199 0.033
purine ribonucleoside catabolic process GO:0046130 112 0.033
single organism catabolic process GO:0044712 228 0.033
ion transport GO:0006811 145 0.032
eye photoreceptor cell differentiation GO:0001754 145 0.032
negative regulation of gene expression GO:0010629 387 0.032
purine ribonucleotide catabolic process GO:0009154 109 0.032
purine nucleoside catabolic process GO:0006152 112 0.032
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.032
negative regulation of biosynthetic process GO:0009890 277 0.032
appendage development GO:0048736 401 0.032
ribonucleoside catabolic process GO:0042454 112 0.031
eye development GO:0001654 323 0.031
regulation of gtpase activity GO:0043087 44 0.031
intracellular signal transduction GO:0035556 300 0.031
ras protein signal transduction GO:0007265 88 0.031
endocytosis GO:0006897 310 0.031
chromatin modification GO:0016568 147 0.031
cellular macromolecule localization GO:0070727 220 0.031
regulation of phosphate metabolic process GO:0019220 210 0.031
regulation of localization GO:0032879 275 0.031
cell maturation GO:0048469 144 0.030
regulation of catabolic process GO:0009894 170 0.030
ribonucleoside metabolic process GO:0009119 127 0.030
purine ribonucleotide metabolic process GO:0009150 145 0.030
nucleotide catabolic process GO:0009166 109 0.029
negative regulation of nucleic acid templated transcription GO:1903507 240 0.029
establishment or maintenance of cell polarity GO:0007163 167 0.028
vesicle localization GO:0051648 55 0.028
respiratory system development GO:0060541 213 0.028
transmembrane transport GO:0055085 139 0.028
single organism biosynthetic process GO:0044711 206 0.028
establishment of vesicle localization GO:0051650 51 0.028
purine nucleoside triphosphate catabolic process GO:0009146 108 0.028
macromolecular complex assembly GO:0065003 256 0.028
cellular nitrogen compound catabolic process GO:0044270 165 0.028
dendrite development GO:0016358 204 0.027
aromatic compound catabolic process GO:0019439 166 0.027
carbohydrate derivative metabolic process GO:1901135 217 0.027
nucleobase containing compound catabolic process GO:0034655 165 0.027
dna metabolic process GO:0006259 227 0.027
Human
enzyme linked receptor protein signaling pathway GO:0007167 179 0.027
transcription from rna polymerase ii promoter GO:0006366 368 0.027
purine nucleoside metabolic process GO:0042278 127 0.027
negative regulation of rna biosynthetic process GO:1902679 240 0.026
positive regulation of signaling GO:0023056 243 0.026
spindle organization GO:0007051 253 0.026
positive regulation of nucleoside metabolic process GO:0045979 47 0.026
secretion GO:0046903 109 0.026
meiotic cell cycle GO:0051321 171 0.026
regulation of cellular localization GO:0060341 136 0.026
regulation of gene expression epigenetic GO:0040029 128 0.026
negative regulation of response to stimulus GO:0048585 258 0.026
mitotic nuclear division GO:0007067 213 0.026
segmentation GO:0035282 207 0.025
immune response GO:0006955 246 0.025
mitotic spindle organization GO:0007052 220 0.025
regulation of cell development GO:0060284 215 0.025
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.025
regulation of intracellular signal transduction GO:1902531 236 0.025
negative regulation of signal transduction GO:0009968 206 0.025
defense response to bacterium GO:0042742 178 0.024
intracellular transport GO:0046907 228 0.024
membrane organization GO:0061024 112 0.024
chemosensory behavior GO:0007635 106 0.024
digestive tract development GO:0048565 149 0.024
ribonucleotide catabolic process GO:0009261 109 0.024
purine nucleotide catabolic process GO:0006195 109 0.023
muscle structure development GO:0061061 224 0.023
regulation of small gtpase mediated signal transduction GO:0051056 93 0.023
negative regulation of rna metabolic process GO:0051253 251 0.023
regulation of neurogenesis GO:0050767 158 0.023
positive regulation of hydrolase activity GO:0051345 78 0.023
locomotory behavior GO:0007626 176 0.023
oocyte differentiation GO:0009994 145 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
protein modification process GO:0036211 438 0.023
Human
nitrogen compound transport GO:0071705 85 0.023
response to other organism GO:0051707 293 0.023
organic cyclic compound catabolic process GO:1901361 168 0.022
regulation of catalytic activity GO:0050790 185 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
purine containing compound catabolic process GO:0072523 112 0.022
cell motility GO:0048870 251 0.022
central nervous system development GO:0007417 201 0.022
phosphorylation GO:0016310 294 0.022
positive regulation of transcription dna templated GO:0045893 266 0.022
ion transmembrane transport GO:0034220 122 0.022
digestive system development GO:0055123 149 0.022
secretion by cell GO:0032940 101 0.022
regulation of ras protein signal transduction GO:0046578 93 0.022
nucleoside metabolic process GO:0009116 127 0.022
digestive tract morphogenesis GO:0048546 127 0.022
positive regulation of cellular biosynthetic process GO:0031328 316 0.022
ribonucleoside triphosphate metabolic process GO:0009199 119 0.022
sensory organ morphogenesis GO:0090596 260 0.022
chromatin remodeling GO:0006338 72 0.022
salivary gland morphogenesis GO:0007435 145 0.022
cellular protein modification process GO:0006464 438 0.021
Human
positive regulation of gtp catabolic process GO:0033126 43 0.021
cell division GO:0051301 248 0.021
compound eye morphogenesis GO:0001745 249 0.021
nucleoside catabolic process GO:0009164 112 0.021
cell adhesion GO:0007155 136 0.021
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.021
eye morphogenesis GO:0048592 260 0.021
glycosyl compound catabolic process GO:1901658 112 0.021
positive regulation of cell communication GO:0010647 250 0.021
organophosphate catabolic process GO:0046434 112 0.021
open tracheal system development GO:0007424 204 0.021
chromatin organization GO:0006325 207 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
regulation of anatomical structure morphogenesis GO:0022603 242 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.021
positive regulation of cellular catabolic process GO:0031331 95 0.020
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.020
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
brain development GO:0007420 120 0.020
male gamete generation GO:0048232 201 0.020
tripartite regional subdivision GO:0007351 103 0.020
axon development GO:0061564 297 0.020
response to external biotic stimulus GO:0043207 293 0.020
phagocytosis GO:0006909 215 0.020
glycosyl compound metabolic process GO:1901657 127 0.020
gtp catabolic process GO:0006184 72 0.020
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.019
cellular homeostasis GO:0019725 80 0.019
dendrite morphogenesis GO:0048813 199 0.019
positive regulation of multicellular organismal process GO:0051240 143 0.019
oocyte development GO:0048599 124 0.019
regulation of nervous system development GO:0051960 248 0.019
purine nucleoside triphosphate metabolic process GO:0009144 119 0.019
nucleoside triphosphate catabolic process GO:0009143 108 0.019
cell proliferation GO:0008283 299 0.019
rna localization GO:0006403 115 0.019
epithelial cell development GO:0002064 274 0.019
protein complex biogenesis GO:0070271 201 0.019
stem cell differentiation GO:0048863 117 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
Human
negative regulation of multicellular organismal process GO:0051241 142 0.019
morphogenesis of a polarized epithelium GO:0001738 93 0.019
taxis GO:0042330 304 0.019
positive regulation of rna biosynthetic process GO:1902680 266 0.018
chromatin silencing GO:0006342 76 0.018
regulation of immune system process GO:0002682 176 0.018
blastoderm segmentation GO:0007350 159 0.018
single organism intracellular transport GO:1902582 207 0.018
organonitrogen compound catabolic process GO:1901565 128 0.018
cell death GO:0008219 279 0.018
positive regulation of catabolic process GO:0009896 105 0.018
axon guidance GO:0007411 233 0.018
ameboidal type cell migration GO:0001667 151 0.018
peptide metabolic process GO:0006518 80 0.018
cell projection assembly GO:0030031 94 0.018
regulation of nucleotide metabolic process GO:0006140 62 0.018
embryonic pattern specification GO:0009880 174 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
developmental growth GO:0048589 280 0.018
tube morphogenesis GO:0035239 191 0.018
negative regulation of organelle organization GO:0010639 56 0.018
gland development GO:0048732 191 0.017
response to oxygen containing compound GO:1901700 200 0.017
olfactory behavior GO:0042048 97 0.017
sensory perception GO:0007600 196 0.017
positive regulation of cellular component organization GO:0051130 156 0.017
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.017
regulation of transport GO:0051049 181 0.017
negative regulation of developmental process GO:0051093 201 0.017
g protein coupled receptor signaling pathway GO:0007186 136 0.017
single organism cellular localization GO:1902580 180 0.017
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.017
regulation of cell morphogenesis GO:0022604 163 0.017
chromosome segregation GO:0007059 157 0.017
body morphogenesis GO:0010171 2 0.017
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.017
regulation of synaptic transmission GO:0050804 69 0.017
heterocycle catabolic process GO:0046700 166 0.016
regulation of cellular catabolic process GO:0031329 157 0.016
notch signaling pathway GO:0007219 120 0.016
response to organic substance GO:0010033 284 0.016
gastrulation GO:0007369 70 0.016
regulation of gtp catabolic process GO:0033124 44 0.016
tissue migration GO:0090130 155 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
positive regulation of gtpase activity GO:0043547 43 0.016
defense response to other organism GO:0098542 225 0.016
detection of stimulus GO:0051606 156 0.016
regulation of hydrolase activity GO:0051336 97 0.015
chemotaxis GO:0006935 249 0.015
oocyte construction GO:0007308 112 0.015
anterior posterior axis specification embryo GO:0008595 103 0.015
regulation of anatomical structure size GO:0090066 163 0.015
regulation of purine nucleotide metabolic process GO:1900542 62 0.015
epithelium migration GO:0090132 148 0.015
embryonic axis specification GO:0000578 107 0.015
learning GO:0007612 75 0.015
exocytosis GO:0006887 28 0.015
positive regulation of molecular function GO:0044093 136 0.015
nucleoside triphosphate metabolic process GO:0009141 120 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
guanosine containing compound catabolic process GO:1901069 74 0.015
immune system process GO:0002376 347 0.014
protein phosphorylation GO:0006468 169 0.014
regulation of neuron projection development GO:0010975 69 0.014
forebrain development GO:0030900 2 0.014
regulation of programmed cell death GO:0043067 152 0.014
humoral immune response GO:0006959 117 0.014
regulation of neuron differentiation GO:0045664 103 0.014
metal ion transport GO:0030001 74 0.014
positive regulation of nucleotide metabolic process GO:0045981 55 0.014
protein complex assembly GO:0006461 200 0.014
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.014
positive regulation of signal transduction GO:0009967 223 0.014
regulation of secretion by cell GO:1903530 39 0.014
meiotic nuclear division GO:0007126 151 0.014
negative regulation of insulin secretion GO:0046676 1 0.014
inorganic ion transmembrane transport GO:0098660 73 0.014
regulation of cell cycle GO:0051726 291 0.014
imaginal disc derived leg morphogenesis GO:0007480 80 0.014
regulation of multi organism process GO:0043900 131 0.014
chromatin assembly GO:0031497 48 0.014
regulation of nucleotide catabolic process GO:0030811 48 0.014
tube development GO:0035295 244 0.014
anterior posterior pattern specification GO:0009952 136 0.014
exocrine system development GO:0035272 162 0.014
regulation of growth GO:0040008 233 0.014
cellular response to chemical stimulus GO:0070887 199 0.014
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.014
establishment of planar polarity GO:0001736 87 0.014
localization of cell GO:0051674 257 0.014
epithelial cell differentiation GO:0030855 322 0.014
heart development GO:0007507 82 0.014
biological adhesion GO:0022610 138 0.014
leg disc morphogenesis GO:0007478 80 0.014
growth GO:0040007 359 0.013
leg disc development GO:0035218 92 0.013
positive regulation of cellular component biogenesis GO:0044089 80 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
regulation of synapse organization GO:0050807 110 0.013
centrosome organization GO:0051297 163 0.013
cellular protein localization GO:0034613 160 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
establishment of tissue polarity GO:0007164 87 0.013
regulation of ras gtpase activity GO:0032318 38 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
death GO:0016265 284 0.013
camera type eye development GO:0043010 4 0.013
innate immune response GO:0045087 144 0.013
response to biotic stimulus GO:0009607 294 0.013
reproductive behavior GO:0019098 122 0.013
negative regulation of peptide hormone secretion GO:0090278 1 0.013
sister chromatid segregation GO:0000819 92 0.013
mapk cascade GO:0000165 107 0.013
rho protein signal transduction GO:0007266 14 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
gtp metabolic process GO:0046039 72 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
salivary gland development GO:0007431 162 0.012
response to heat GO:0009408 63 0.012
anterior posterior axis specification GO:0009948 109 0.012
rrna processing GO:0006364 3 0.012
dna packaging GO:0006323 91 0.012
pole plasm assembly GO:0007315 61 0.012
photoreceptor cell fate commitment GO:0046552 41 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
regulation of cell cycle process GO:0010564 181 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
microtubule based transport GO:0010970 42 0.012
antimicrobial humoral response GO:0019730 99 0.012
endomembrane system organization GO:0010256 119 0.012
regulation of nucleoside metabolic process GO:0009118 50 0.012
cellular amide metabolic process GO:0043603 80 0.012
cellular protein complex disassembly GO:0043624 35 0.012
programmed cell death GO:0012501 257 0.012
amine metabolic process GO:0009308 12 0.012
response to wounding GO:0009611 94 0.012
cyclic purine nucleotide metabolic process GO:0052652 25 0.012
inorganic cation transmembrane transport GO:0098662 61 0.012
intracellular mrna localization GO:0008298 66 0.012
protein modification by small protein conjugation GO:0032446 79 0.012
Human
circulatory system development GO:0072359 82 0.012
regulation of response to stress GO:0080134 200 0.012
retina development in camera type eye GO:0060041 4 0.012
microtubule polymerization or depolymerization GO:0031109 39 0.012
neurological system process GO:0050877 358 0.012
eye photoreceptor cell fate commitment GO:0042706 37 0.012
positive regulation of macromolecule metabolic process GO:0010604 405 0.011
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
skin development GO:0043588 65 0.011
protein ubiquitination GO:0016567 70 0.011
Human
mrna metabolic process GO:0016071 124 0.011
negative regulation of phosphate metabolic process GO:0045936 45 0.011
peripheral nervous system development GO:0007422 52 0.011
columnar cuboidal epithelial cell development GO:0002066 249 0.011
positive regulation of gene expression GO:0010628 290 0.011
apoptotic process GO:0006915 159 0.011
oocyte anterior posterior axis specification GO:0007314 72 0.011
regulation of cell projection organization GO:0031344 92 0.011
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.011
carbohydrate derivative biosynthetic process GO:1901137 85 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
regulation of purine nucleotide catabolic process GO:0033121 48 0.011
autophagic cell death GO:0048102 83 0.011
photoreceptor cell development GO:0042461 96 0.011
convergent extension GO:0060026 2 0.011
neurotransmitter secretion GO:0007269 35 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.011
ovarian follicle cell development GO:0030707 248 0.011
establishment of protein localization GO:0045184 163 0.011
negative regulation of cell cycle process GO:0010948 109 0.011
signal release GO:0023061 49 0.011
imaginal disc pattern formation GO:0007447 91 0.011
rna processing GO:0006396 147 0.011
cognition GO:0050890 141 0.011
macromolecule catabolic process GO:0009057 161 0.011
protein transport GO:0015031 155 0.010
muscle organ development GO:0007517 127 0.010
spermatogenesis GO:0007283 200 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
maternal determination of anterior posterior axis embryo GO:0008358 74 0.010
positive regulation of ras gtpase activity GO:0032320 36 0.010
response to bacterium GO:0009617 198 0.010
regulation of neurotransmitter levels GO:0001505 38 0.010
positive regulation of phosphate metabolic process GO:0045937 139 0.010
metal ion homeostasis GO:0055065 44 0.010
negative regulation of peptide secretion GO:0002792 1 0.010
divalent inorganic cation homeostasis GO:0072507 29 0.010
ribonucleotide biosynthetic process GO:0009260 28 0.010
positive regulation of cell migration GO:0030335 2 0.010
compound eye photoreceptor fate commitment GO:0001752 36 0.010

HERC2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.069
nervous system disease DOID:863 0 0.036
cardiovascular system disease DOID:1287 0 0.025
sensory system disease DOID:0050155 0 0.015
disease of metabolism DOID:0014667 0 0.011
central nervous system disease DOID:331 0 0.011