Drosophila melanogaster

106 known processes

TfIIFalpha (Dmel_CG10281)

Transcription factor IIFalpha

(Aliases: TFIIFalpha,RAP74,Dmel\CG10281,CG10281,TfIIF,TFIIF,154355_at,F5a,DmTFIIF,TFIIF-L)

TfIIFalpha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell cycle GO:0051726 291 0.201
regulation of cell proliferation GO:0042127 163 0.131
embryo development ending in birth or egg hatching GO:0009792 152 0.122
Worm
macromolecular complex assembly GO:0065003 256 0.113
g2 dna damage checkpoint GO:0031572 69 0.112
regulation of cell cycle process GO:0010564 181 0.112
cell motility GO:0048870 251 0.109
negative regulation of cell cycle phase transition GO:1901988 103 0.107
regulation of cell morphogenesis GO:0022604 163 0.105
regulation of cellular protein metabolic process GO:0032268 243 0.104
regulation of protein metabolic process GO:0051246 256 0.097
positive regulation of macromolecule metabolic process GO:0010604 405 0.094
negative regulation of cellular biosynthetic process GO:0031327 277 0.092
establishment of localization in cell GO:0051649 402 0.092
negative regulation of biosynthetic process GO:0009890 277 0.088
cellular protein modification process GO:0006464 438 0.086
mitotic dna damage checkpoint GO:0044773 74 0.085
negative regulation of signal transduction GO:0009968 206 0.082
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.082
regulation of cell differentiation GO:0045595 302 0.081
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.080
positive regulation of multicellular organismal process GO:0051240 143 0.079
phosphorylation GO:0016310 294 0.077
epithelial cell development GO:0002064 274 0.077
negative regulation of rna metabolic process GO:0051253 251 0.075
intracellular signal transduction GO:0035556 300 0.073
cell division GO:0051301 248 0.071
positive regulation of gene expression GO:0010628 290 0.069
ameboidal type cell migration GO:0001667 151 0.069
enzyme linked receptor protein signaling pathway GO:0007167 179 0.067
regulation of cell shape GO:0008360 113 0.067
regulation of phosphate metabolic process GO:0019220 210 0.066
posttranscriptional regulation of gene expression GO:0010608 145 0.065
regulation of anatomical structure morphogenesis GO:0022603 242 0.063
negative regulation of cellular metabolic process GO:0031324 382 0.062
epithelial cell differentiation GO:0030855 322 0.061
regulation of multicellular organismal development GO:2000026 414 0.060
respiratory system development GO:0060541 213 0.060
dna damage checkpoint GO:0000077 78 0.058
cell cycle checkpoint GO:0000075 95 0.058
small molecule metabolic process GO:0044281 305 0.057
protein modification process GO:0036211 438 0.055
negative regulation of gene expression GO:0010629 387 0.054
rna processing GO:0006396 147 0.054
cell cycle phase transition GO:0044770 140 0.052
developmental maturation GO:0021700 172 0.051
organic substance transport GO:0071702 257 0.050
immune effector process GO:0002252 98 0.050
organonitrogen compound metabolic process GO:1901564 318 0.048
mitotic g2 dna damage checkpoint GO:0007095 69 0.047
intracellular transport GO:0046907 228 0.047
vesicle mediated transport GO:0016192 381 0.047
Worm
positive regulation of response to stimulus GO:0048584 323 0.046
oocyte differentiation GO:0009994 145 0.045
endocytosis GO:0006897 310 0.045
Worm
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.045
mitotic dna integrity checkpoint GO:0044774 75 0.045
cellular macromolecular complex assembly GO:0034622 153 0.044
negative regulation of response to stimulus GO:0048585 258 0.044
positive regulation of transcription dna templated GO:0045893 266 0.044
protein phosphorylation GO:0006468 169 0.043
stem cell differentiation GO:0048863 117 0.042
positive regulation of rna metabolic process GO:0051254 271 0.042
mrna processing GO:0006397 104 0.042
regulation of phosphorus metabolic process GO:0051174 210 0.041
regulation of phosphorylation GO:0042325 147 0.041
multi organism behavior GO:0051705 175 0.041
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.041
larval development GO:0002164 104 0.041
body morphogenesis GO:0010171 2 0.041
negative regulation of developmental process GO:0051093 201 0.041
appendage development GO:0048736 401 0.041
mrna metabolic process GO:0016071 124 0.041
protein complex biogenesis GO:0070271 201 0.040
transcription from rna polymerase ii promoter GO:0006366 368 0.040
cellular response to chemical stimulus GO:0070887 199 0.040
posttranscriptional gene silencing GO:0016441 46 0.039
negative regulation of cell cycle process GO:0010948 109 0.039
cellular response to dna damage stimulus GO:0006974 223 0.038
negative regulation of cell communication GO:0010648 223 0.038
negative regulation of multicellular organismal process GO:0051241 142 0.038
tube morphogenesis GO:0035239 191 0.038
catabolic process GO:0009056 409 0.037
positive regulation of cellular protein metabolic process GO:0032270 118 0.037
neurological system process GO:0050877 358 0.036
response to organic substance GO:0010033 284 0.036
molting cycle GO:0042303 56 0.036
nuclear pore organization GO:0006999 1 0.036
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.036
nuclear division GO:0000280 332 0.035
regulation of transport GO:0051049 181 0.034
cellular response to organic substance GO:0071310 132 0.034
response to organic cyclic compound GO:0014070 89 0.034
response to biotic stimulus GO:0009607 294 0.033
regulation of intracellular signal transduction GO:1902531 236 0.033
negative regulation of cellular protein metabolic process GO:0032269 85 0.033
positive regulation of nucleic acid templated transcription GO:1903508 266 0.032
actin filament based process GO:0030029 220 0.032
signal transduction by phosphorylation GO:0023014 107 0.032
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
cell migration GO:0016477 238 0.032
single organism cellular localization GO:1902580 180 0.032
negative regulation of signaling GO:0023057 219 0.031
positive regulation of protein metabolic process GO:0051247 128 0.031
regulation of response to external stimulus GO:0032101 115 0.031
cell proliferation GO:0008283 299 0.031
regulation of multi organism process GO:0043900 131 0.030
post embryonic appendage morphogenesis GO:0035120 385 0.030
protein targeting to nucleus GO:0044744 51 0.029
positive regulation of cellular component biogenesis GO:0044089 80 0.029
positive regulation of signaling GO:0023056 243 0.029
response to other organism GO:0051707 293 0.029
jak stat cascade GO:0007259 49 0.028
positive regulation of cellular biosynthetic process GO:0031328 316 0.028
positive regulation of developmental process GO:0051094 143 0.028
small gtpase mediated signal transduction GO:0007264 88 0.028
reproductive system development GO:0061458 74 0.028
Worm
positive regulation of biosynthetic process GO:0009891 316 0.027
single organism biosynthetic process GO:0044711 206 0.027
columnar cuboidal epithelial cell development GO:0002066 249 0.027
homeostatic process GO:0042592 199 0.027
ovarian follicle cell development GO:0030707 248 0.027
defense response GO:0006952 300 0.027
mitotic cell cycle checkpoint GO:0007093 88 0.027
regulation of cell cycle phase transition GO:1901987 130 0.026
response to external biotic stimulus GO:0043207 293 0.026
negative regulation of cell proliferation GO:0008285 69 0.026
embryonic development via the syncytial blastoderm GO:0001700 148 0.026
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.025
dna integrity checkpoint GO:0031570 81 0.024
imaginal disc derived appendage morphogenesis GO:0035114 395 0.024
glycosyl compound catabolic process GO:1901658 112 0.024
regulation of localization GO:0032879 275 0.024
negative regulation of rna biosynthetic process GO:1902679 240 0.024
regulation of transferase activity GO:0051338 58 0.024
immune system process GO:0002376 347 0.023
positive regulation of cellular component organization GO:0051130 156 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
regulation of programmed cell death GO:0043067 152 0.023
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.023
positive regulation of signal transduction GO:0009967 223 0.022
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.022
mitotic nuclear division GO:0007067 213 0.022
nucleoside triphosphate metabolic process GO:0009141 120 0.022
cell adhesion GO:0007155 136 0.022
response to endogenous stimulus GO:0009719 119 0.022
negative regulation of nucleic acid templated transcription GO:1903507 240 0.022
ras protein signal transduction GO:0007265 88 0.021
rna localization GO:0006403 115 0.021
regulation of organelle organization GO:0033043 196 0.021
organelle fission GO:0048285 340 0.021
cellular amino acid metabolic process GO:0006520 61 0.021
protein localization GO:0008104 284 0.021
regulation of immune system process GO:0002682 176 0.020
nitrogen compound transport GO:0071705 85 0.020
regulation of protein modification process GO:0031399 112 0.020
rna splicing via transesterification reactions GO:0000375 73 0.020
imaginal disc derived wing morphogenesis GO:0007476 337 0.020
appendage morphogenesis GO:0035107 397 0.020
morphogenesis of an epithelium GO:0002009 276 0.019
guanosine containing compound metabolic process GO:1901068 74 0.019
negative regulation of cell differentiation GO:0045596 143 0.019
programmed cell death GO:0012501 257 0.019
phagocytosis GO:0006909 215 0.019
chromosome localization GO:0050000 20 0.019
spindle organization GO:0007051 253 0.018
wing disc morphogenesis GO:0007472 344 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.018
protein localization to organelle GO:0033365 82 0.018
mitotic spindle organization GO:0007052 220 0.018
negative regulation of protein metabolic process GO:0051248 85 0.018
response to nitrogen compound GO:1901698 90 0.018
nuclear transcribed mrna catabolic process GO:0000956 24 0.018
negative regulation of phosphate metabolic process GO:0045936 45 0.017
regulation of response to biotic stimulus GO:0002831 63 0.017
tissue morphogenesis GO:0048729 297 0.017
response to bacterium GO:0009617 198 0.017
regulation of cell death GO:0010941 173 0.017
localization of cell GO:0051674 257 0.017
camera type eye development GO:0043010 4 0.017
response to temperature stimulus GO:0009266 106 0.017
regulation of meiosis GO:0040020 3 0.017
regionalization GO:0003002 416 0.017
ribonucleoprotein complex subunit organization GO:0071826 28 0.016
gene silencing GO:0016458 138 0.016
reproductive structure development GO:0048608 74 0.016
Worm
locomotory behavior GO:0007626 176 0.016
regulation of catalytic activity GO:0050790 185 0.016
cell maturation GO:0048469 144 0.016
actin cytoskeleton organization GO:0030036 206 0.016
positive regulation of protein import into nucleus GO:0042307 21 0.016
oocyte axis specification GO:0007309 108 0.016
oxoacid metabolic process GO:0043436 103 0.016
regulation of protein phosphorylation GO:0001932 64 0.016
positive regulation of phosphorus metabolic process GO:0010562 139 0.016
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.016
imaginal disc derived appendage development GO:0048737 399 0.016
cellular protein localization GO:0034613 160 0.016
single organism catabolic process GO:0044712 228 0.016
circulatory system process GO:0003013 37 0.015
organic cyclic compound catabolic process GO:1901361 168 0.015
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.015
rna splicing GO:0008380 83 0.015
nucleotide metabolic process GO:0009117 161 0.015
dephosphorylation GO:0016311 51 0.015
cell cycle g1 s phase transition GO:0044843 31 0.015
regulation of production of molecular mediator of immune response GO:0002700 44 0.015
meiotic cell cycle GO:0051321 171 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
organic substance catabolic process GO:1901575 308 0.015
negative regulation of transcription dna templated GO:0045892 237 0.015
mitotic g2 m transition checkpoint GO:0044818 70 0.015
secretion by cell GO:0032940 101 0.015
tube development GO:0035295 244 0.015
positive regulation of immune response GO:0050778 63 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
histone mrna metabolic process GO:0008334 8 0.014
developmental growth GO:0048589 280 0.014
positive regulation of mapk cascade GO:0043410 63 0.014
cytoplasmic transport GO:0016482 130 0.014
positive regulation of cell communication GO:0010647 250 0.014
biological adhesion GO:0022610 138 0.014
positive regulation of response to external stimulus GO:0032103 44 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
posttranscriptional gene silencing by rna GO:0035194 45 0.014
regulation of mapk cascade GO:0043408 92 0.014
negative regulation of programmed cell death GO:0043069 72 0.014
protein transport GO:0015031 155 0.014
regulation of cellular amine metabolic process GO:0033238 3 0.014
mitotic cell cycle phase transition GO:0044772 138 0.014
axon development GO:0061564 297 0.014
inositol lipid mediated signaling GO:0048017 4 0.013
regulation of molecular function GO:0065009 217 0.013
regulation of response to stress GO:0080134 200 0.013
regulation of humoral immune response GO:0002920 51 0.013
mrna splicing via spliceosome GO:0000398 73 0.013
embryonic pattern specification GO:0009880 174 0.013
response to oxygen containing compound GO:1901700 200 0.013
positive regulation of intracellular signal transduction GO:1902533 116 0.013
chromatin modification GO:0016568 147 0.013
covalent chromatin modification GO:0016569 106 0.012
mapk cascade GO:0000165 107 0.012
organic acid metabolic process GO:0006082 103 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
establishment of protein localization to organelle GO:0072594 62 0.012
establishment of protein localization GO:0045184 163 0.012
response to dsrna GO:0043331 15 0.012
regulation of kinase activity GO:0043549 53 0.012
tissue migration GO:0090130 155 0.012
positive regulation of immune system process GO:0002684 68 0.012
gene silencing by rna GO:0031047 57 0.012
blastoderm segmentation GO:0007350 159 0.012
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
response to abiotic stimulus GO:0009628 341 0.012
regulation of immune effector process GO:0002697 52 0.012
eggshell formation GO:0030703 105 0.011
negative regulation of cell cycle GO:0045786 116 0.011
epithelial tube morphogenesis GO:0060562 88 0.011
negative regulation of cell death GO:0060548 81 0.011
chorion containing eggshell formation GO:0007304 105 0.011
gonad development GO:0008406 50 0.011
Worm
growth GO:0040007 359 0.011
positive regulation of humoral immune response GO:0002922 28 0.011
maintenance of location GO:0051235 73 0.011
response to heat GO:0009408 63 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
cellular macromolecule localization GO:0070727 220 0.011
positive regulation of erk1 and erk2 cascade GO:0070374 36 0.011
anatomical structure homeostasis GO:0060249 97 0.011
gland development GO:0048732 191 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
single organism nuclear import GO:1902593 51 0.011
organophosphate metabolic process GO:0019637 195 0.011
oocyte construction GO:0007308 112 0.011
protein import GO:0017038 55 0.011
regulation of erk1 and erk2 cascade GO:0070372 39 0.011
response to wounding GO:0009611 94 0.010
regulation of growth GO:0040008 233 0.010
positive regulation of protein modification process GO:0031401 58 0.010
production of molecular mediator of immune response GO:0002440 46 0.010
nucleoside phosphate catabolic process GO:1901292 110 0.010
cellular catabolic process GO:0044248 372 0.010
translation GO:0006412 69 0.010
embryonic morphogenesis GO:0048598 206 0.010
central nervous system development GO:0007417 201 0.010
regulation of mitotic cell cycle phase transition GO:1901990 130 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
nucleobase containing compound transport GO:0015931 56 0.010
macromolecule catabolic process GO:0009057 161 0.010

TfIIFalpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.014