Drosophila melanogaster

83 known processes

SuUR (Dmel_CG7869)

Suppressor of Under-Replication

(Aliases: su(UR)ES,SUUR,SU(UR),Su(UR)ES,Su(UR),CG7869,Dromel_CG7869_FBtr0076203_suur_mORF,Dmel\CG7869)

SuUR biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
gene silencing GO:0016458 138 0.934
negative regulation of cellular biosynthetic process GO:0031327 277 0.907
regulation of gene expression epigenetic GO:0040029 128 0.900
heterochromatin organization GO:0070828 25 0.890
chromosome organization GO:0051276 360 0.835
chromatin silencing GO:0006342 76 0.780
dna conformation change GO:0071103 105 0.738
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.682
negative regulation of rna biosynthetic process GO:1902679 240 0.682
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.668
negative regulation of transcription dna templated GO:0045892 237 0.660
dna metabolic process GO:0006259 227 0.642
negative regulation of biosynthetic process GO:0009890 277 0.615
histone acetylation GO:0016573 38 0.572
negative regulation of gene expression epigenetic GO:0045814 77 0.566
positive regulation of biosynthetic process GO:0009891 316 0.555
positive regulation of cellular biosynthetic process GO:0031328 316 0.540
negative regulation of gene expression GO:0010629 387 0.523
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.501
heterochromatin organization involved in chromatin silencing GO:0070868 9 0.494
dna packaging GO:0006323 91 0.466
covalent chromatin modification GO:0016569 106 0.464
negative regulation of nucleic acid templated transcription GO:1903507 240 0.449
transcription from rna polymerase ii promoter GO:0006366 368 0.428
posttranscriptional gene silencing by rna GO:0035194 45 0.422
negative regulation of rna metabolic process GO:0051253 251 0.393
mitotic dna damage checkpoint GO:0044773 74 0.375
protein acetylation GO:0006473 39 0.350
learning GO:0007612 75 0.314
organelle fission GO:0048285 340 0.308
protein dna complex assembly GO:0065004 63 0.305
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.290
regulation of gene silencing GO:0060968 63 0.286
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.285
meiotic cell cycle process GO:1903046 132 0.273
cellular response to radiation GO:0071478 52 0.269
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.267
protein dna complex subunit organization GO:0071824 86 0.238
nuclear division GO:0000280 332 0.237
chromatin assembly GO:0031497 48 0.229
chromatin remodeling GO:0006338 72 0.196
positive regulation of gene expression GO:0010628 290 0.195
positive regulation of transcription dna templated GO:0045893 266 0.193
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.189
positive regulation of rna metabolic process GO:0051254 271 0.189
positive regulation of response to stimulus GO:0048584 323 0.189
chromatin organization GO:0006325 207 0.187
g2 dna damage checkpoint GO:0031572 69 0.179
mitotic g2 m transition checkpoint GO:0044818 70 0.178
induction of programmed cell death by ecdysone GO:0035078 12 0.168
internal peptidyl lysine acetylation GO:0018393 38 0.156
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.156
macromolecular complex assembly GO:0065003 256 0.155
negative regulation of cellular metabolic process GO:0031324 382 0.150
epithelial cell differentiation GO:0030855 322 0.140
dendrite development GO:0016358 204 0.133
cellular response to extracellular stimulus GO:0031668 64 0.126
positive regulation of macromolecule metabolic process GO:0010604 405 0.124
digestive system development GO:0055123 149 0.121
positive regulation of nucleic acid templated transcription GO:1903508 266 0.120
growth GO:0040007 359 0.118
regulation of nurse cell apoptotic process GO:0045477 9 0.115
nucleosome organization GO:0034728 59 0.115
peptidyl lysine acetylation GO:0018394 39 0.113
internal protein amino acid acetylation GO:0006475 38 0.112
cellular response to unfolded protein GO:0034620 9 0.111
macroautophagy GO:0016236 42 0.109
histone modification GO:0016570 106 0.101
cell cycle checkpoint GO:0000075 95 0.101
chromatin modification GO:0016568 147 0.099
muscle structure development GO:0061061 224 0.087
negative regulation of cell communication GO:0010648 223 0.086
protein acylation GO:0043543 42 0.084
cell cycle dna replication GO:0044786 23 0.084
cellular response to dna damage stimulus GO:0006974 223 0.083
regulation of protein metabolic process GO:0051246 256 0.081
protein modification process GO:0036211 438 0.080
associative learning GO:0008306 65 0.079
embryo development ending in birth or egg hatching GO:0009792 152 0.079
negative regulation of signal transduction GO:0009968 206 0.076
cell proliferation GO:0008283 299 0.073
body morphogenesis GO:0010171 2 0.071
regulation of developmental growth GO:0048638 174 0.071
regulation of transcription by chromatin organization GO:0034401 3 0.071
response to sterol GO:0036314 34 0.070
regulation of cellular amino acid metabolic process GO:0006521 0 0.070
gland development GO:0048732 191 0.070
regulation of chromatin silencing GO:0031935 36 0.069
chromosome condensation GO:0030261 41 0.068
eggshell chorion gene amplification GO:0007307 9 0.067
positive regulation of developmental growth GO:0048639 62 0.067
male meiosis GO:0007140 52 0.066
digestive tract development GO:0048565 149 0.064
exocrine system development GO:0035272 162 0.064
mitotic g2 dna damage checkpoint GO:0007095 69 0.063
positive regulation of growth GO:0045927 75 0.063
positive regulation of rna biosynthetic process GO:1902680 266 0.061
regulation of peptidyl lysine acetylation GO:2000756 7 0.059
posttranscriptional regulation of gene expression GO:0010608 145 0.058
gene silencing by rna GO:0031047 57 0.057
tube morphogenesis GO:0035239 191 0.055
negative regulation of response to stimulus GO:0048585 258 0.055
regulation of organelle organization GO:0033043 196 0.054
positive regulation of autophagy GO:0010508 21 0.052
response to other organism GO:0051707 293 0.052
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.051
intracellular signal transduction GO:0035556 300 0.050
regulation of cellular protein metabolic process GO:0032268 243 0.050
positive regulation of developmental process GO:0051094 143 0.050
regulation of cellular ketone metabolic process GO:0010565 3 0.050
induction of programmed cell death by hormones GO:0035081 12 0.050
catabolic process GO:0009056 409 0.050
establishment of localization in cell GO:0051649 402 0.049
hormone catabolic process GO:0042447 3 0.049
regulation of growth GO:0040008 233 0.048
post embryonic appendage morphogenesis GO:0035120 385 0.048
response to oxygen containing compound GO:1901700 200 0.047
mitotic chromosome condensation GO:0007076 22 0.046
dna damage checkpoint GO:0000077 78 0.046
meiotic chromosome segregation GO:0045132 59 0.046
negative regulation of cell differentiation GO:0045596 143 0.045
response to abiotic stimulus GO:0009628 341 0.045
central nervous system development GO:0007417 201 0.045
negative regulation of developmental growth GO:0048640 64 0.045
negative regulation of signaling GO:0023057 219 0.044
dendrite morphogenesis GO:0048813 199 0.044
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.043
dna replication GO:0006260 48 0.042
cellular macromolecule catabolic process GO:0044265 136 0.042
digestive tract morphogenesis GO:0048546 127 0.041
gastrulation GO:0007369 70 0.041
male gamete generation GO:0048232 201 0.040
carboxylic acid metabolic process GO:0019752 92 0.039
cellular catabolic process GO:0044248 372 0.039
columnar cuboidal epithelial cell development GO:0002066 249 0.038
posttranscriptional gene silencing GO:0016441 46 0.037
response to external biotic stimulus GO:0043207 293 0.037
negative regulation of cell cycle process GO:0010948 109 0.037
induction of programmed cell death GO:0012502 12 0.036
ecdysone receptor mediated signaling pathway GO:0035076 11 0.036
response to radiation GO:0009314 155 0.036
larval development GO:0002164 104 0.036
cellular response to external stimulus GO:0071496 66 0.036
negative regulation of developmental process GO:0051093 201 0.035
ncrna metabolic process GO:0034660 43 0.035
ecdysone mediated induction of salivary gland cell autophagic cell death GO:0035072 12 0.033
positive regulation of histone acetylation GO:0035066 3 0.033
positive regulation of signal transduction GO:0009967 223 0.033
learning or memory GO:0007611 141 0.033
regulation of tube diameter GO:0035296 14 0.033
cellular macromolecular complex assembly GO:0034622 153 0.032
protein catabolic process GO:0030163 101 0.032
dna integrity checkpoint GO:0031570 81 0.031
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.031
regulation of response to gamma radiation GO:2001228 4 0.031
forebrain development GO:0030900 2 0.031
regulation of autophagy GO:0010506 62 0.031
response to biotic stimulus GO:0009607 294 0.031
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.030
nucleosome positioning GO:0016584 3 0.030
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.030
regionalization GO:0003002 416 0.029
protein complex assembly GO:0006461 200 0.029
rna processing GO:0006396 147 0.028
camera type eye development GO:0043010 4 0.028
mesodermal cell migration GO:0008078 7 0.028
response to starvation GO:0042594 97 0.028
imaginal disc derived wing morphogenesis GO:0007476 337 0.028
proteolysis GO:0006508 192 0.028
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
response to alcohol GO:0097305 95 0.027
regulation of immune system process GO:0002682 176 0.027
larval midgut histolysis GO:0035069 22 0.026
regulation of histone acetylation GO:0035065 7 0.026
limb development GO:0060173 1 0.026
meiotic cell cycle GO:0051321 171 0.026
chromatin assembly or disassembly GO:0006333 52 0.026
atp dependent chromatin remodeling GO:0043044 22 0.025
defense response to other organism GO:0098542 225 0.025
nucleosome mobilization GO:0042766 9 0.025
response to organic substance GO:0010033 284 0.025
macromolecule catabolic process GO:0009057 161 0.025
developmental programmed cell death GO:0010623 138 0.025
positive regulation of defense response GO:0031349 59 0.025
imaginal disc growth GO:0007446 37 0.025
autophagy GO:0006914 108 0.025
positive regulation of multicellular organismal process GO:0051240 143 0.024
positive regulation of cell cycle GO:0045787 43 0.024
defense response GO:0006952 300 0.024
production of small rna involved in gene silencing by rna GO:0070918 15 0.024
determination of adult lifespan GO:0008340 137 0.024
positive regulation of immune response GO:0050778 63 0.024
single organism biosynthetic process GO:0044711 206 0.024
histolysis GO:0007559 102 0.024
regulation of cysteine type endopeptidase activity GO:2000116 27 0.024
cell cycle phase transition GO:0044770 140 0.024
regulation of multicellular organism growth GO:0040014 40 0.023
aging GO:0007568 143 0.023
cellular protein catabolic process GO:0044257 83 0.022
cognition GO:0050890 141 0.022
response to ketone GO:1901654 34 0.022
regulation of programmed cell death GO:0043067 152 0.022
histone h3 k9 acetylation GO:0043970 3 0.022
gland morphogenesis GO:0022612 145 0.022
regulation of organ growth GO:0046620 42 0.021
regulation of cellular amine metabolic process GO:0033238 3 0.021
appendage morphogenesis GO:0035107 397 0.021
response to extracellular stimulus GO:0009991 116 0.021
negative regulation of homeostatic process GO:0032845 2 0.021
single organism behavior GO:0044708 391 0.021
positive regulation of signaling GO:0023056 243 0.021
negative regulation of nervous system development GO:0051961 92 0.021
limb morphogenesis GO:0035108 1 0.021
ribonucleoprotein complex biogenesis GO:0022613 31 0.021
axonogenesis GO:0007409 290 0.021
organic acid metabolic process GO:0006082 103 0.021
oxidation reduction process GO:0055114 123 0.020
oxoacid metabolic process GO:0043436 103 0.020
appendage development GO:0048736 401 0.020
gastrulation with mouth forming first GO:0001703 36 0.020
wing disc morphogenesis GO:0007472 344 0.020
positive regulation of cellular component organization GO:0051130 156 0.020
cellular response to light stimulus GO:0071482 37 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
negative regulation of mitotic cell cycle GO:0045930 109 0.020
negative regulation of cellular component organization GO:0051129 108 0.020
spermatogenesis GO:0007283 200 0.020
axon guidance GO:0007411 233 0.020
multicellular organismal aging GO:0010259 140 0.020
regulation of dna metabolic process GO:0051052 34 0.020
organelle assembly GO:0070925 198 0.019
regulation of heterochromatin assembly GO:0031445 8 0.019
regulation of cell fate specification GO:0042659 27 0.019
response to ecdysone GO:0035075 34 0.019
tissue death GO:0016271 102 0.019
regulation of phosphatase activity GO:0010921 3 0.018
cell recognition GO:0008037 102 0.018
rna interference GO:0016246 27 0.018
negative regulation of neurogenesis GO:0050768 53 0.018
regulation of mitosis GO:0007088 56 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
histone exchange GO:0043486 21 0.018
cellular protein modification process GO:0006464 438 0.017
cellular response to reactive oxygen species GO:0034614 14 0.017
histone h4 k20 methylation GO:0034770 4 0.017
translation GO:0006412 69 0.017
salivary gland histolysis GO:0035070 88 0.017
cellular respiration GO:0045333 26 0.017
insulin receptor signaling pathway GO:0008286 25 0.017
protein complex biogenesis GO:0070271 201 0.017
response to ionizing radiation GO:0010212 32 0.017
female meiosis chromosome segregation GO:0016321 33 0.017
notch signaling pathway GO:0007219 120 0.017
cellular response to chemical stimulus GO:0070887 199 0.017
estrogen metabolic process GO:0008210 1 0.016
regulation of mitotic cell cycle GO:0007346 190 0.016
mating GO:0007618 120 0.016
axon development GO:0061564 297 0.016
transmembrane transport GO:0055085 139 0.016
positive regulation of cellular protein metabolic process GO:0032270 118 0.016
regulation of chromatin modification GO:1903308 28 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
regulation of cellular component biogenesis GO:0044087 201 0.016
response to lipopolysaccharide GO:0032496 4 0.016
imaginal disc derived appendage morphogenesis GO:0035114 395 0.016
oocyte maturation GO:0001556 3 0.016
positive regulation of cellular amine metabolic process GO:0033240 0 0.016
metal ion homeostasis GO:0055065 44 0.016
positive regulation of cell communication GO:0010647 250 0.016
pole cell formation GO:0007279 19 0.015
sex differentiation GO:0007548 81 0.015
fatty acid beta oxidation GO:0006635 6 0.015
ribonucleoside monophosphate catabolic process GO:0009158 39 0.015
heterocycle catabolic process GO:0046700 166 0.015
regulation of translation GO:0006417 56 0.015
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
purine nucleoside monophosphate metabolic process GO:0009126 50 0.015
larval midgut cell programmed cell death GO:0035096 19 0.015
regulation of cell differentiation GO:0045595 302 0.015
modification dependent protein catabolic process GO:0019941 78 0.015
cation homeostasis GO:0055080 51 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
regulation of localization GO:0032879 275 0.014
apoptotic process involved in development GO:1902742 20 0.014
regulation of sequestering of calcium ion GO:0051282 3 0.014
regulation of response to dna damage stimulus GO:2001020 23 0.014
male pronucleus assembly GO:0035039 6 0.014
positive regulation of organelle organization GO:0010638 65 0.014
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.014
branching morphogenesis of an epithelial tube GO:0048754 45 0.014
regulation of proteolysis GO:0030162 87 0.014
response to organic cyclic compound GO:0014070 89 0.014
mrna metabolic process GO:0016071 124 0.013
inositol lipid mediated signaling GO:0048017 4 0.013
sterol homeostasis GO:0055092 4 0.013
regulation of cell cycle GO:0051726 291 0.013
adult behavior GO:0030534 137 0.013
mitotic sister chromatid segregation GO:0000070 87 0.013
regulation of multi organism process GO:0043900 131 0.013
salivary gland morphogenesis GO:0007435 145 0.013
intracellular transport GO:0046907 228 0.013
hindbrain development GO:0030902 2 0.013
regulation of chromosome organization GO:0033044 64 0.013
tube development GO:0035295 244 0.013
histone h2a acetylation GO:0043968 1 0.013
anterior posterior pattern specification GO:0009952 136 0.013
developmental growth involved in morphogenesis GO:0060560 65 0.012
peptidyl lysine modification GO:0018205 57 0.012
regulation of photoreceptor cell differentiation GO:0046532 34 0.012
regulation of gliogenesis GO:0014013 11 0.012
organelle fusion GO:0048284 46 0.012
developmental growth GO:0048589 280 0.012
response to nutrient levels GO:0031667 114 0.012
mitotic nuclear division GO:0007067 213 0.012
meiosis i GO:0007127 59 0.012
sulfur compound metabolic process GO:0006790 59 0.012
single organism carbohydrate metabolic process GO:0044723 72 0.012
telencephalon development GO:0021537 2 0.012
camera type eye morphogenesis GO:0048593 2 0.012
neuron recognition GO:0008038 101 0.012
positive regulation of innate immune response GO:0045089 38 0.012
protein localization GO:0008104 284 0.012
histone h3 acetylation GO:0043966 11 0.012
phosphatidylinositol mediated signaling GO:0048015 4 0.012
negative regulation of cell cycle phase transition GO:1901988 103 0.011
targeting of mrna for destruction involved in rna interference GO:0030423 4 0.011
defense response to bacterium GO:0042742 178 0.011
dna methylation or demethylation GO:0044728 4 0.011
regulation of chromatin assembly GO:0010847 9 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
dna methylation GO:0006306 4 0.011
skin development GO:0043588 65 0.011
regulation of cell proliferation GO:0042127 163 0.011
olfactory learning GO:0008355 56 0.011
regulation of nuclear division GO:0051783 58 0.011
negative regulation of small gtpase mediated signal transduction GO:0051058 13 0.011
epithelial cell development GO:0002064 274 0.011
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
organ growth GO:0035265 56 0.011
dna endoreduplication GO:0042023 22 0.011
salivary gland cell autophagic cell death GO:0035071 83 0.011
brain development GO:0007420 120 0.011
meiotic nuclear division GO:0007126 151 0.011
chemosensory behavior GO:0007635 106 0.011
tricarboxylic acid metabolic process GO:0072350 1 0.011
citrate metabolic process GO:0006101 0 0.011
cytoplasmic transport GO:0016482 130 0.010
chromosome segregation GO:0007059 157 0.010
release of sequestered calcium ion into cytosol GO:0051209 1 0.010
response to topologically incorrect protein GO:0035966 10 0.010
dna amplification GO:0006277 11 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
dna templated transcription initiation GO:0006352 25 0.010
immune response GO:0006955 246 0.010
aromatic compound catabolic process GO:0019439 166 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
gene silencing by mirna GO:0035195 22 0.010
programmed cell death GO:0012501 257 0.010
taxis GO:0042330 304 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010

SuUR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024