Drosophila melanogaster

121 known processes

lmg (Dmel_CG34440)

lemming

(Aliases: Dmel_CG18042,Dmel\CG34440,Apc11,CG18042,l(2)03424,CG34440,Dromel_CG18042_FBtr0079695_lmg_uORF)

lmg biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cell development GO:0060284 215 0.424
regulation of neuron projection development GO:0010975 69 0.405
telencephalon development GO:0021537 2 0.396
regulation of neuron differentiation GO:0045664 103 0.368
regulation of neurogenesis GO:0050767 158 0.353
regulation of photoreceptor cell differentiation GO:0046532 34 0.345
cellular response to extracellular stimulus GO:0031668 64 0.276
regulation of endopeptidase activity GO:0052548 36 0.257
positive regulation of endopeptidase activity GO:0010950 26 0.251
regulation of gene expression epigenetic GO:0040029 128 0.246
regulation of nervous system development GO:0051960 248 0.237
regulation of multicellular organismal development GO:2000026 414 0.226
positive regulation of multicellular organismal process GO:0051240 143 0.217
positive regulation of nervous system development GO:0051962 69 0.203
internal protein amino acid acetylation GO:0006475 38 0.185
eye photoreceptor cell differentiation GO:0001754 145 0.184
meiotic cell cycle GO:0051321 171 0.160
negative regulation of response to stimulus GO:0048585 258 0.150
head development GO:0060322 135 0.147
posttranscriptional gene silencing by rna GO:0035194 45 0.145
regulation of protein metabolic process GO:0051246 256 0.143
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.141
regulation of anatomical structure morphogenesis GO:0022603 242 0.136
positive regulation of peptidase activity GO:0010952 29 0.132
positive regulation of proteolysis GO:0045862 52 0.131
synapse assembly GO:0007416 143 0.129
gene silencing GO:0016458 138 0.128
dendrite development GO:0016358 204 0.126
negative regulation of nervous system development GO:0051961 92 0.121
exocrine system development GO:0035272 162 0.118
negative regulation of neurogenesis GO:0050768 53 0.115
photoreceptor cell differentiation GO:0046530 170 0.114
central nervous system development GO:0007417 201 0.113
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.112
gene silencing by rna GO:0031047 57 0.108
positive regulation of cell development GO:0010720 61 0.107
positive regulation of signal transduction GO:0009967 223 0.105
response to ionizing radiation GO:0010212 32 0.104
r7 cell differentiation GO:0045466 43 0.100
neuroblast proliferation GO:0007405 74 0.098
positive regulation of autophagy GO:0010508 21 0.094
regulation of phosphorylation GO:0042325 147 0.091
protein complex biogenesis GO:0070271 201 0.087
phosphorylation GO:0016310 294 0.087
chromosome organization GO:0051276 360 0.086
transcription from rna polymerase ii promoter GO:0006366 368 0.086
regulation of cellular protein metabolic process GO:0032268 243 0.084
salivary gland development GO:0007431 162 0.084
cell death GO:0008219 279 0.081
imaginal disc growth GO:0007446 37 0.081
defense response GO:0006952 300 0.080
appendage morphogenesis GO:0035107 397 0.078
brain development GO:0007420 120 0.076
positive regulation of cell communication GO:0010647 250 0.075
enzyme linked receptor protein signaling pathway GO:0007167 179 0.072
regulation of cysteine type endopeptidase activity GO:2000116 27 0.072
determination of adult lifespan GO:0008340 137 0.071
pigment metabolic process GO:0042440 84 0.071
cellular component assembly involved in morphogenesis GO:0010927 151 0.071
synapse organization GO:0050808 196 0.070
salivary gland morphogenesis GO:0007435 145 0.069
dendrite morphogenesis GO:0048813 199 0.069
regulation of cell differentiation GO:0045595 302 0.069
chromatin modification GO:0016568 147 0.067
negative regulation of signal transduction GO:0009968 206 0.066
regulation of cellular response to stress GO:0080135 89 0.066
protein phosphorylation GO:0006468 169 0.064
regulation of peptidase activity GO:0052547 39 0.063
response to wounding GO:0009611 94 0.063
death GO:0016265 284 0.062
regulation of organ morphogenesis GO:2000027 78 0.062
oxoacid metabolic process GO:0043436 103 0.062
forebrain development GO:0030900 2 0.062
cellular response to chemical stimulus GO:0070887 199 0.061
positive regulation of protein metabolic process GO:0051247 128 0.061
spindle organization GO:0007051 253 0.061
positive regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043280 23 0.061
regulation of cellular component biogenesis GO:0044087 201 0.061
regulation of hydrolase activity GO:0051336 97 0.061
positive regulation of phosphorus metabolic process GO:0010562 139 0.060
histolysis GO:0007559 102 0.059
taxis GO:0042330 304 0.058
meiotic nuclear division GO:0007126 151 0.057
autophagic cell death GO:0048102 83 0.055
multicellular organismal aging GO:0010259 140 0.054
cell growth GO:0016049 108 0.053
dna metabolic process GO:0006259 227 0.053
cellular ketone metabolic process GO:0042180 24 0.052
posttranscriptional gene silencing GO:0016441 46 0.051
protein acylation GO:0043543 42 0.049
regionalization GO:0003002 416 0.049
positive regulation of developmental process GO:0051094 143 0.048
protein acetylation GO:0006473 39 0.048
autophagy GO:0006914 108 0.047
lateral inhibition GO:0046331 206 0.047
female meiosis chromosome segregation GO:0016321 33 0.047
salivary gland cell autophagic cell death GO:0035071 83 0.046
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.045
response to organic substance GO:0010033 284 0.045
catabolic process GO:0009056 409 0.045
negative regulation of multicellular organismal process GO:0051241 142 0.045
body morphogenesis GO:0010171 2 0.044
leg disc development GO:0035218 92 0.044
mushroom body development GO:0016319 70 0.044
amine metabolic process GO:0009308 12 0.044
defense response to other organism GO:0098542 225 0.043
gland development GO:0048732 191 0.043
positive regulation of rna biosynthetic process GO:1902680 266 0.043
nuclear division GO:0000280 332 0.042
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.042
regulation of cell cycle phase transition GO:1901987 130 0.042
positive regulation of cellular biosynthetic process GO:0031328 316 0.041
cellular macromolecule catabolic process GO:0044265 136 0.041
translation GO:0006412 69 0.041
regulation of organelle organization GO:0033043 196 0.041
regulation of proteolysis GO:0030162 87 0.041
regulation of phosphorus metabolic process GO:0051174 210 0.040
regulation of cellular catabolic process GO:0031329 157 0.040
posttranscriptional regulation of gene expression GO:0010608 145 0.040
positive regulation of mitotic cell cycle GO:0045931 34 0.039
regulation of catabolic process GO:0009894 170 0.038
regulation of cell projection organization GO:0031344 92 0.038
regulation of response to stress GO:0080134 200 0.038
positive regulation of molecular function GO:0044093 136 0.038
regulation of cellular ketone metabolic process GO:0010565 3 0.038
regulation of cellular amino acid metabolic process GO:0006521 0 0.038
cellular response to sterol depletion GO:0071501 3 0.038
cellular amino acid metabolic process GO:0006520 61 0.037
stem cell division GO:0017145 69 0.037
programmed cell death GO:0012501 257 0.036
border follicle cell migration GO:0007298 113 0.036
negative regulation of cell development GO:0010721 62 0.036
regulation of cellular amine metabolic process GO:0033238 3 0.036
positive regulation of neurogenesis GO:0050769 41 0.036
extrinsic apoptotic signaling pathway GO:0097191 1 0.036
negative regulation of transcription dna templated GO:0045892 237 0.036
imaginal disc derived wing morphogenesis GO:0007476 337 0.035
localization of cell GO:0051674 257 0.035
cell cell signaling involved in cell fate commitment GO:0045168 210 0.035
positive regulation of intracellular signal transduction GO:1902533 116 0.035
positive regulation of response to stimulus GO:0048584 323 0.035
positive regulation of cellular component organization GO:0051130 156 0.034
endomitotic cell cycle GO:0007113 7 0.034
covalent chromatin modification GO:0016569 106 0.034
aging GO:0007568 143 0.034
wound healing GO:0042060 75 0.033
negative regulation of neuron apoptotic process GO:0043524 14 0.033
regulation of cysteine type endopeptidase activity involved in apoptotic process GO:0043281 25 0.033
outflow tract morphogenesis GO:0003151 4 0.033
organelle assembly GO:0070925 198 0.033
zymogen activation GO:0031638 20 0.033
intracellular signal transduction GO:0035556 300 0.033
cellular macromolecular complex assembly GO:0034622 153 0.032
negative regulation of signaling GO:0023057 219 0.032
positive regulation of macroautophagy GO:0016239 8 0.032
proteolysis GO:0006508 192 0.032
protein complex assembly GO:0006461 200 0.032
eye morphogenesis GO:0048592 260 0.032
compound eye morphogenesis GO:0001745 249 0.032
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.031
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.031
negative regulation of cell communication GO:0010648 223 0.031
negative regulation of developmental process GO:0051093 201 0.031
regulation of mitotic cell cycle GO:0007346 190 0.030
negative regulation of g1 s transition of mitotic cell cycle GO:2000134 13 0.030
cell cycle checkpoint GO:0000075 95 0.030
apoptotic process GO:0006915 159 0.030
cellular response to external stimulus GO:0071496 66 0.030
negative regulation of neuron death GO:1901215 18 0.030
gonad morphogenesis GO:0035262 7 0.029
macromolecular complex assembly GO:0065003 256 0.029
meiotic spindle organization GO:0000212 36 0.029
muscle cell development GO:0055001 50 0.029
regulation of chromosome organization GO:0033044 64 0.028
wing disc morphogenesis GO:0007472 344 0.028
female meiotic division GO:0007143 70 0.028
cellular protein modification process GO:0006464 438 0.028
modification dependent protein catabolic process GO:0019941 78 0.028
hippo signaling GO:0035329 20 0.028
regulation of mitotic cell cycle phase transition GO:1901990 130 0.027
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.027
positive regulation of phosphorylation GO:0042327 87 0.027
organophosphate biosynthetic process GO:0090407 46 0.027
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.027
male gamete generation GO:0048232 201 0.027
eye antennal disc development GO:0035214 60 0.027
imaginal disc derived leg morphogenesis GO:0007480 80 0.027
response to alcohol GO:0097305 95 0.027
regulation of epithelial cell differentiation GO:0030856 4 0.027
organelle fission GO:0048285 340 0.027
regulation of mapk cascade GO:0043408 92 0.027
negative regulation of apoptotic process GO:0043066 63 0.026
regulation of protein modification process GO:0031399 112 0.026
chitin based cuticle sclerotization GO:0007593 19 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
activation of cysteine type endopeptidase activity GO:0097202 17 0.026
epiboly GO:0090504 2 0.026
chromatin silencing GO:0006342 76 0.026
leg disc morphogenesis GO:0007478 80 0.026
response to x ray GO:0010165 8 0.026
positive regulation of signaling GO:0023056 243 0.025
negative regulation of kinase activity GO:0033673 16 0.025
positive regulation of cellular protein metabolic process GO:0032270 118 0.025
regulation of cytoskeleton organization GO:0051493 89 0.025
positive regulation of hydrolase activity GO:0051345 78 0.025
pigmentation GO:0043473 75 0.025
cellular amine metabolic process GO:0044106 12 0.025
positive regulation of apoptotic signaling pathway GO:2001235 4 0.025
photoreceptor cell development GO:0042461 96 0.024
positive regulation of cellular amine metabolic process GO:0033240 0 0.024
phagocytosis GO:0006909 215 0.024
negative regulation of programmed cell death GO:0043069 72 0.024
positive regulation of r7 cell differentiation GO:0045678 7 0.024
negative regulation of cellular component organization GO:0051129 108 0.024
regulation of axonogenesis GO:0050770 32 0.024
macromolecule catabolic process GO:0009057 161 0.024
innate immune response GO:0045087 144 0.024
response to external biotic stimulus GO:0043207 293 0.024
single organism biosynthetic process GO:0044711 206 0.024
protein processing GO:0016485 68 0.023
mitotic cell cycle embryonic GO:0045448 38 0.023
cuticle development GO:0042335 86 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
regulation of cell cycle process GO:0010564 181 0.023
sensory organ morphogenesis GO:0090596 260 0.023
cellular response to organic substance GO:0071310 132 0.023
positive regulation of response to extracellular stimulus GO:0032106 8 0.023
glial cell differentiation GO:0010001 35 0.022
positive regulation of transcription dna templated GO:0045893 266 0.022
regulation of sister chromatid segregation GO:0033045 28 0.022
dorsal ventral axis specification GO:0009950 66 0.022
regulation of programmed cell death GO:0043067 152 0.022
organ growth GO:0035265 56 0.022
regulation of protein acetylation GO:1901983 7 0.021
histoblast morphogenesis GO:0007488 9 0.021
developmental pigmentation GO:0048066 68 0.021
molting cycle chitin based cuticle GO:0007591 56 0.021
response to oxygen containing compound GO:1901700 200 0.021
synaptic growth at neuromuscular junction GO:0051124 119 0.021
lipid biosynthetic process GO:0008610 46 0.021
protein polymerization GO:0051258 42 0.021
response to hexose GO:0009746 3 0.021
organic acid metabolic process GO:0006082 103 0.021
gland morphogenesis GO:0022612 145 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
er nucleus signaling pathway GO:0006984 9 0.021
tissue death GO:0016271 102 0.021
positive regulation of organ growth GO:0046622 12 0.020
mitotic sister chromatid separation GO:0051306 30 0.020
negative regulation of cell differentiation GO:0045596 143 0.020
post embryonic appendage morphogenesis GO:0035120 385 0.020
response to other organism GO:0051707 293 0.020
small molecule metabolic process GO:0044281 305 0.020
endocytosis GO:0006897 310 0.020
response to organic cyclic compound GO:0014070 89 0.020
regulation of intracellular signal transduction GO:1902531 236 0.020
cell division GO:0051301 248 0.020
positive regulation of metaphase anaphase transition of cell cycle GO:1902101 10 0.020
mitotic cell cycle checkpoint GO:0007093 88 0.020
positive regulation of nucleic acid templated transcription GO:1903508 266 0.020
digestive tract morphogenesis GO:0048546 127 0.019
regulation of catalytic activity GO:0050790 185 0.019
regulation of imaginal disc growth GO:0045570 26 0.019
regulation of stem cell proliferation GO:0072091 40 0.019
cellular lipid metabolic process GO:0044255 83 0.019
actomyosin structure organization GO:0031032 56 0.019
nucleoside phosphate metabolic process GO:0006753 162 0.019
cellular response to dna damage stimulus GO:0006974 223 0.019
asymmetric stem cell division GO:0098722 49 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
regulation of autophagy GO:0010506 62 0.019
circadian rhythm GO:0007623 105 0.019
protein localization GO:0008104 284 0.019
neuronal stem cell division GO:0036445 35 0.019
melanin metabolic process GO:0006582 47 0.019
positive regulation of rna metabolic process GO:0051254 271 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
negative regulation of catalytic activity GO:0043086 42 0.018
necrotic cell death GO:0070265 1 0.018
apoptotic signaling pathway GO:0097190 27 0.018
positive regulation of chromosome segregation GO:0051984 10 0.018
positive regulation of cellular component biogenesis GO:0044089 80 0.018
epithelial cell development GO:0002064 274 0.018
regulation of neuron death GO:1901214 26 0.018
positive regulation of cell differentiation GO:0045597 64 0.018
epidermal growth factor receptor signaling pathway GO:0007173 58 0.018
immune response GO:0006955 246 0.018
response to biotic stimulus GO:0009607 294 0.018
eye photoreceptor cell development GO:0042462 81 0.018
positive regulation of protein binding GO:0032092 1 0.018
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.018
axonogenesis GO:0007409 290 0.017
stem cell proliferation GO:0072089 88 0.017
mitochondrion organization GO:0007005 65 0.017
positive regulation of response to external stimulus GO:0032103 44 0.017
cuticle pigmentation GO:0048067 22 0.017
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.017
erbb signaling pathway GO:0038127 58 0.017
protein maturation GO:0051604 71 0.017
wnt signaling pathway GO:0016055 98 0.017
negative regulation of phosphorylation GO:0042326 35 0.017
positive regulation of gene expression epigenetic GO:0045815 16 0.017
regulation of organ growth GO:0046620 42 0.017
negative regulation of gene expression epigenetic GO:0045814 77 0.017
cell motility GO:0048870 251 0.017
regulation of cell death GO:0010941 173 0.017
organonitrogen compound metabolic process GO:1901564 318 0.016
regulation of erbb signaling pathway GO:1901184 42 0.016
positive regulation of cell cycle GO:0045787 43 0.016
purine nucleotide metabolic process GO:0006163 146 0.016
positive regulation of protein modification process GO:0031401 58 0.016
positive regulation of catalytic activity GO:0043085 118 0.016
salivary gland histolysis GO:0035070 88 0.016
protein modification process GO:0036211 438 0.016
mitotic nuclear division GO:0007067 213 0.016
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.016
gene silencing by mirna GO:0035195 22 0.016
response to abiotic stimulus GO:0009628 341 0.016
peptidyl lysine acetylation GO:0018394 39 0.016
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.016
nephron tubule development GO:0072080 3 0.016
actin cytoskeleton organization GO:0030036 206 0.016
positive regulation of mapk cascade GO:0043410 63 0.016
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.015
vesicle mediated transport GO:0016192 381 0.015
regulation of chromatin organization GO:1902275 32 0.015
mitotic cell cycle phase transition GO:0044772 138 0.015
spermatogenesis GO:0007283 200 0.015
activation of cysteine type endopeptidase activity involved in apoptotic process GO:0006919 16 0.015
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.015
regulation of mitotic sister chromatid separation GO:0010965 28 0.015
regulation of cell cycle GO:0051726 291 0.015
meiotic cell cycle process GO:1903046 132 0.015
positive regulation of developmental growth GO:0048639 62 0.015
response to ecdysone GO:0035075 34 0.015
regulation of cell morphogenesis GO:0022604 163 0.015
negative regulation of cell death GO:0060548 81 0.015
r7 cell development GO:0045467 14 0.015
protein localization to chromatin GO:0071168 3 0.015
epiboly involved in wound healing GO:0090505 2 0.015
dopamine biosynthetic process GO:0042416 3 0.015
positive regulation of neuron differentiation GO:0045666 26 0.015
purine ribonucleotide catabolic process GO:0009154 109 0.015
endosomal transport GO:0016197 44 0.015
organic hydroxy compound metabolic process GO:1901615 83 0.015
negative regulation of phosphate metabolic process GO:0045936 45 0.014
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.014
circulatory system development GO:0072359 82 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
stem cell differentiation GO:0048863 117 0.014
hematopoietic progenitor cell differentiation GO:0002244 1 0.014
cellular protein catabolic process GO:0044257 83 0.014
positive regulation of protein phosphorylation GO:0001934 34 0.014
centrosome duplication GO:0051298 121 0.014
cellular catabolic process GO:0044248 372 0.014
meiosis i GO:0007127 59 0.014
developmental maturation GO:0021700 172 0.014
response to ketone GO:1901654 34 0.013
regulation of localization GO:0032879 275 0.013
regulation of synapse structure and activity GO:0050803 128 0.013
centrosome organization GO:0051297 163 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
positive regulation of macromolecule metabolic process GO:0010604 405 0.013
eye development GO:0001654 323 0.013
cell adhesion GO:0007155 136 0.013
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.013
stem cell development GO:0048864 79 0.013
regulation of gene silencing by mirna GO:0060964 8 0.013
regulation of translation GO:0006417 56 0.013
molting cycle process GO:0022404 29 0.013
compound eye development GO:0048749 307 0.012
response to endoplasmic reticulum stress GO:0034976 28 0.012
regulation of gene silencing GO:0060968 63 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
positive regulation of programmed cell death GO:0043068 62 0.012
neuron death GO:0070997 27 0.012
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.012
negative regulation of photoreceptor cell differentiation GO:0046533 8 0.012
regulation of molecular function GO:0065009 217 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
regulation of defense response GO:0031347 102 0.012
organic substance catabolic process GO:1901575 308 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
anatomical structure homeostasis GO:0060249 97 0.012
positive regulation of cell adhesion GO:0045785 10 0.012
striated muscle cell development GO:0055002 50 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
response to transforming growth factor beta GO:0071559 18 0.011
negative regulation of fibroblast growth factor receptor signaling pathway GO:0040037 2 0.011
biological adhesion GO:0022610 138 0.011
morphogenesis of an epithelium GO:0002009 276 0.011
regulation of response to external stimulus GO:0032101 115 0.011
compound eye photoreceptor development GO:0042051 78 0.011
regulation of protein kinase activity GO:0045859 51 0.011
neuroblast division GO:0055057 35 0.011
hematopoietic or lymphoid organ development GO:0048534 57 0.011
nucleobase containing compound catabolic process GO:0034655 165 0.011
regulation of cuticle pigmentation GO:0048079 16 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
regulation of actin cytoskeleton organization GO:0032956 42 0.011
regulation of wnt signaling pathway GO:0030111 68 0.011
molting cycle GO:0042303 56 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
nucleotide metabolic process GO:0009117 161 0.011
positive regulation of organelle organization GO:0010638 65 0.011
negative regulation of phosphorus metabolic process GO:0010563 45 0.011
tube morphogenesis GO:0035239 191 0.011
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.011
positive regulation of axonogenesis GO:0050772 2 0.011
regulation of protein serine threonine kinase activity GO:0071900 25 0.011
negative regulation of neural precursor cell proliferation GO:2000178 27 0.011
regulation of hippo signaling GO:0035330 14 0.010
peptidyl amino acid modification GO:0018193 105 0.010
skin development GO:0043588 65 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
organic cyclic compound catabolic process GO:1901361 168 0.010
nephron epithelium morphogenesis GO:0072088 3 0.010
developmental programmed cell death GO:0010623 138 0.010
developmental growth GO:0048589 280 0.010

lmg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.040
disease of cellular proliferation DOID:14566 0 0.040
organ system cancer DOID:0050686 0 0.040