Drosophila melanogaster

180 known processes

tup (Dmel_CG10619)

tailup

(Aliases: Tup,Isl,Dmel\CG10619,l(2)37Aa,CG10619,isl,islet,l(2)E41)

tup biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
motor neuron axon guidance GO:0008045 58 0.999
dendrite guidance GO:0070983 21 0.997
tissue morphogenesis GO:0048729 297 0.975
embryonic morphogenesis GO:0048598 206 0.963
negative regulation of transcription dna templated GO:0045892 237 0.956
Mouse Fly
torso signaling pathway GO:0008293 21 0.956
neuron projection guidance GO:0097485 241 0.934
negative regulation of developmental process GO:0051093 201 0.900
Mouse
axonogenesis GO:0007409 290 0.879
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.875
Mouse Fly
imaginal disc derived leg morphogenesis GO:0007480 80 0.860
Fly
regulation of nervous system development GO:0051960 248 0.857
Mouse
segmentation GO:0035282 207 0.853
amnioserosa maintenance GO:0046665 5 0.846
synapse organization GO:0050808 196 0.841
terminal region determination GO:0007362 25 0.838
negative regulation of rna biosynthetic process GO:1902679 240 0.820
Mouse Fly
embryonic development via the syncytial blastoderm GO:0001700 148 0.819
morphogenesis of an epithelium GO:0002009 276 0.813
regulation of cell differentiation GO:0045595 302 0.793
Mouse
dorsal ventral pattern formation GO:0009953 133 0.784
Fly
imaginal disc derived leg segmentation GO:0036011 26 0.782
Fly
leg disc morphogenesis GO:0007478 80 0.780
Fly
regulation of dendrite morphogenesis GO:0048814 28 0.779
embryo development ending in birth or egg hatching GO:0009792 152 0.766
regionalization GO:0003002 416 0.753
zygotic determination of anterior posterior axis embryo GO:0007354 27 0.743
chemotaxis GO:0006935 249 0.722
tube development GO:0035295 244 0.686
Worm
axon development GO:0061564 297 0.679
axon guidance GO:0007411 233 0.679
regulation of neuron projection development GO:0010975 69 0.670
taxis GO:0042330 304 0.668
synapse assembly GO:0007416 143 0.667
brain development GO:0007420 120 0.666
Mouse
stem cell maintenance GO:0019827 67 0.661
positive regulation of rna biosynthetic process GO:1902680 266 0.654
muscle cell fate commitment GO:0042693 14 0.653
morphogenesis of embryonic epithelium GO:0016331 94 0.638
anterior posterior pattern specification GO:0009952 136 0.637
chaeta development GO:0022416 97 0.628
blastoderm segmentation GO:0007350 159 0.621
developmental growth GO:0048589 280 0.617
Zebrafish
negative regulation of cell differentiation GO:0045596 143 0.594
Mouse
cardiac cell fate determination GO:0060913 3 0.585
Human Mouse
multi multicellular organism process GO:0044706 123 0.581
ameboidal type cell migration GO:0001667 151 0.571
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.560
dendrite morphogenesis GO:0048813 199 0.550
heart morphogenesis GO:0003007 32 0.534
Human Mouse
negative regulation of gene expression GO:0010629 387 0.514
Mouse Fly
digestive tract development GO:0048565 149 0.513
Worm
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.508
Mouse
negative regulation of nucleic acid templated transcription GO:1903507 240 0.507
Mouse Fly
developmental growth involved in morphogenesis GO:0060560 65 0.504
Zebrafish
leg disc development GO:0035218 92 0.496
Fly
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.496
cell fate determination GO:0001709 91 0.463
urogenital system development GO:0001655 72 0.452
cell motility GO:0048870 251 0.446
Mouse
regulation of synapse assembly GO:0051963 94 0.442
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.435
regulation of organ morphogenesis GO:2000027 78 0.432
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.429
Mouse
lymph gland development GO:0048542 28 0.429
appendage development GO:0048736 401 0.419
Fly
epithelial cell differentiation GO:0030855 322 0.399
Zebrafish
kidney development GO:0001822 3 0.390
nephron development GO:0072006 3 0.387
dendrite development GO:0016358 204 0.383
imaginal disc derived appendage development GO:0048737 399 0.381
Fly
circulatory system development GO:0072359 82 0.379
post embryonic appendage morphogenesis GO:0035120 385 0.377
Fly
chaeta morphogenesis GO:0008407 42 0.374
compound eye development GO:0048749 307 0.368
Fly
regulation of anatomical structure size GO:0090066 163 0.366
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.364
Mouse Fly
reproductive behavior GO:0019098 122 0.359
somatic muscle development GO:0007525 66 0.357
Fly
cardioblast cell fate determination GO:0007510 3 0.339
dorsal closure GO:0007391 79 0.339
appendage segmentation GO:0035285 26 0.339
Fly
sensory organ morphogenesis GO:0090596 260 0.336
multicellular organismal reproductive behavior GO:0033057 110 0.331
regulation of multicellular organismal development GO:2000026 414 0.330
Mouse
gastrulation GO:0007369 70 0.325
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.306
eye morphogenesis GO:0048592 260 0.304
post embryonic hemopoiesis GO:0035166 17 0.297
positive regulation of growth GO:0045927 75 0.287
imaginal disc pattern formation GO:0007447 91 0.286
Fly
negative regulation of rna metabolic process GO:0051253 251 0.279
Mouse Fly
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.266
regulation of axonogenesis GO:0050770 32 0.258
appendage morphogenesis GO:0035107 397 0.250
Fly
wing disc morphogenesis GO:0007472 344 0.248
heart development GO:0007507 82 0.246
axis specification GO:0009798 167 0.242
nephron epithelium development GO:0072009 3 0.242
nephron tubule morphogenesis GO:0072078 3 0.241
homeostatic process GO:0042592 199 0.236
positive regulation of multicellular organismal process GO:0051240 143 0.235
Mouse
cell migration GO:0016477 238 0.235
Mouse
nephron morphogenesis GO:0072028 3 0.233
regulation of cell development GO:0060284 215 0.230
Mouse
wing disc pattern formation GO:0035222 66 0.228
Fly
muscle structure development GO:0061061 224 0.227
hemocyte differentiation GO:0042386 38 0.223
positive regulation of developmental growth GO:0048639 62 0.222
positive regulation of nucleic acid templated transcription GO:1903508 266 0.218
leg disc proximal distal pattern formation GO:0007479 9 0.217
Fly
kidney epithelium development GO:0072073 3 0.216
synaptic target recognition GO:0008039 45 0.216
neuron recognition GO:0008038 101 0.215
cardiovascular system development GO:0072358 82 0.215
embryonic pattern specification GO:0009880 174 0.209
larval development GO:0002164 104 0.206
Worm Fly
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.205
Mouse Fly
retinal ganglion cell axon guidance GO:0031290 12 0.202
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.200
hindbrain development GO:0030902 2 0.199
imaginal disc derived appendage morphogenesis GO:0035114 395 0.198
Fly
photoreceptor cell axon guidance GO:0072499 23 0.198
reproductive structure development GO:0048608 74 0.198
Worm
regulation of dendrite development GO:0050773 37 0.190
imaginal disc derived wing morphogenesis GO:0007476 337 0.188
cardiocyte differentiation GO:0035051 29 0.183
Human Zebrafish Mouse
regulation of cell morphogenesis GO:0022604 163 0.181
positive regulation of axonogenesis GO:0050772 2 0.179
synaptic growth at neuromuscular junction GO:0051124 119 0.179
cell fate specification GO:0001708 71 0.176
negative regulation of cellular biosynthetic process GO:0031327 277 0.170
Mouse Fly
negative regulation of nervous system development GO:0051961 92 0.169
Mouse
nephron epithelium morphogenesis GO:0072088 3 0.168
positive regulation of rna metabolic process GO:0051254 271 0.167
stem cell differentiation GO:0048863 117 0.166
Mouse
formation of primary germ layer GO:0001704 24 0.162
spinal cord development GO:0021510 1 0.162
Zebrafish Mouse
mushroom body development GO:0016319 70 0.160
epithelial cell development GO:0002064 274 0.158
Zebrafish
regulation of developmental growth GO:0048638 174 0.157
anatomical structure homeostasis GO:0060249 97 0.154
larval lymph gland hemopoiesis GO:0035167 17 0.153
stem cell development GO:0048864 79 0.151
Mouse
eye development GO:0001654 323 0.145
Fly
regulation of r7 cell differentiation GO:0045676 15 0.143
head development GO:0060322 135 0.140
Mouse Worm
connective tissue development GO:0061448 3 0.136
renal tubule development GO:0061326 64 0.135
multi organism reproductive behavior GO:0044705 121 0.133
digestive system development GO:0055123 149 0.128
Zebrafish Worm
body morphogenesis GO:0010171 2 0.128
Worm
telencephalon development GO:0021537 2 0.125
regulation of growth GO:0040008 233 0.120
determination of dorsal ventral asymmetry GO:0048262 3 0.119
nephron tubule development GO:0072080 3 0.117
regulation of epithelial cell differentiation GO:0030856 4 0.116
kidney morphogenesis GO:0060993 3 0.116
cell recognition GO:0008037 102 0.115
gland development GO:0048732 191 0.111
regulation of synapse organization GO:0050807 110 0.110
negative regulation of growth GO:0045926 84 0.108
regulation of neuron differentiation GO:0045664 103 0.107
Mouse
wing disc dorsal ventral pattern formation GO:0048190 47 0.107
Fly
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.102
growth GO:0040007 359 0.102
Zebrafish
regulation of cellular component biogenesis GO:0044087 201 0.102
positive regulation of cell differentiation GO:0045597 64 0.101
forebrain development GO:0030900 2 0.100
Mouse
regulation of apoptotic process GO:0042981 130 0.099
Mouse
negative regulation of biosynthetic process GO:0009890 277 0.098
Mouse Fly
muscle organ development GO:0007517 127 0.097
Mouse Fly
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.092
single organism behavior GO:0044708 391 0.092
tripartite regional subdivision GO:0007351 103 0.089
muscle cell differentiation GO:0042692 103 0.086
positive regulation of cellular component biogenesis GO:0044089 80 0.084
positive regulation of cell communication GO:0010647 250 0.083
Mouse Rat
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.082
Fly
renal system development GO:0072001 72 0.081
cell proliferation GO:0008283 299 0.078
Mouse
retina development in camera type eye GO:0060041 4 0.075
morphogenesis of a branching epithelium GO:0061138 45 0.075
notum cell fate specification GO:0035310 5 0.074
muscle tissue morphogenesis GO:0060415 2 0.073
Mouse
positive regulation of nervous system development GO:0051962 69 0.072
central nervous system neuron differentiation GO:0021953 8 0.072
Zebrafish Mouse
formation of anatomical boundary GO:0048859 37 0.071
germ line stem cell maintenance GO:0030718 50 0.069
regulation of antimicrobial humoral response GO:0002759 50 0.069
endocrine system development GO:0035270 5 0.067
Zebrafish Mouse
cell fate commitment involved in pattern specification GO:0060581 31 0.067
positive regulation of response to stimulus GO:0048584 323 0.066
Mouse
germ band shortening GO:0007390 19 0.066
organ growth GO:0035265 56 0.065
regulation of response to stress GO:0080134 200 0.065
Mouse
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.064
positive regulation of signaling GO:0023056 243 0.064
Mouse Rat
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.063
negative regulation of developmental growth GO:0048640 64 0.063
dorsal ventral axon guidance GO:0033563 2 0.062
cell fate specification involved in pattern specification GO:0060573 8 0.062
cellular response to hormone stimulus GO:0032870 44 0.062
Rat
periodic partitioning GO:0007365 29 0.061
neuroblast differentiation GO:0014016 29 0.060
digestive tract morphogenesis GO:0048546 127 0.059
positive regulation of biosynthetic process GO:0009891 316 0.059
regulation of cell cycle GO:0051726 291 0.059
Fly
regulation of axon extension involved in axon guidance GO:0048841 4 0.059
regulation of synapse structure and activity GO:0050803 128 0.059
neuron migration GO:0001764 5 0.058
tube morphogenesis GO:0035239 191 0.058
embryonic hemopoiesis GO:0035162 26 0.057
response to wounding GO:0009611 94 0.057
Mouse Rat
embryonic epithelial tube formation GO:0001838 6 0.056
determination of ventral identity GO:0048264 1 0.055
sex differentiation GO:0007548 81 0.055
Worm
axonal fasciculation GO:0007413 12 0.053
cell division GO:0051301 248 0.053
morphogenesis of a branching structure GO:0001763 45 0.052
neuroblast development GO:0014019 13 0.051
regulation of cell death GO:0010941 173 0.051
Mouse
blood circulation GO:0008015 26 0.051
Zebrafish
anterior posterior axis specification GO:0009948 109 0.051
regulation of epithelial cell proliferation GO:0050678 4 0.051
eye antennal disc development GO:0035214 60 0.050
segment specification GO:0007379 33 0.050
reproductive system development GO:0061458 74 0.049
Worm
positive regulation of synapse assembly GO:0051965 29 0.048
mesoderm morphogenesis GO:0048332 22 0.048
negative regulation of cellular metabolic process GO:0031324 382 0.048
Mouse Fly
adipose tissue development GO:0060612 2 0.046
regulation of cell size GO:0008361 63 0.046
positive regulation of axon extension GO:0045773 2 0.043
embryonic heart tube development GO:0035050 22 0.043
enzyme linked receptor protein signaling pathway GO:0007167 179 0.043
positive regulation of cellular biosynthetic process GO:0031328 316 0.043
cardioblast differentiation GO:0010002 20 0.042
Mouse
regulation of programmed cell death GO:0043067 152 0.042
Mouse
regulation of hemocyte differentiation GO:0045610 22 0.041
neuron death GO:0070997 27 0.041
Mouse
immune system process GO:0002376 347 0.041
regulation of neurogenesis GO:0050767 158 0.041
Mouse
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.041
Mouse Fly
neuron projection extension GO:1990138 32 0.040
Zebrafish
epithelial tube morphogenesis GO:0060562 88 0.040
branching morphogenesis of an epithelial tube GO:0048754 45 0.040
regulation of cellular component size GO:0032535 98 0.040
apoptotic process involved in morphogenesis GO:0060561 3 0.039
positive regulation of cellular component organization GO:0051130 156 0.039
positive regulation of developmental process GO:0051094 143 0.039
Mouse
feeding behavior GO:0007631 50 0.039
determination of muscle attachment site GO:0016204 7 0.039
negative regulation of multicellular organismal process GO:0051241 142 0.038
Mouse
positive regulation of gene expression GO:0010628 290 0.038
exocrine system development GO:0035272 162 0.037
Zebrafish
phagocytosis GO:0006909 215 0.037
positive regulation of macromolecule metabolic process GO:0010604 405 0.037
cell death GO:0008219 279 0.037
Mouse
central nervous system development GO:0007417 201 0.037
Zebrafish Mouse
meiotic nuclear division GO:0007126 151 0.036
neuron fate commitment GO:0048663 50 0.035
Zebrafish Mouse
positive regulation of synaptic growth at neuromuscular junction GO:0045887 26 0.035
cellular macromolecule localization GO:0070727 220 0.034
hematopoietic progenitor cell differentiation GO:0002244 1 0.034
multicellular organismal homeostasis GO:0048871 41 0.033
immune response GO:0006955 246 0.032
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.032
regulation of cellular response to stress GO:0080135 89 0.032
respiratory system development GO:0060541 213 0.032
development of primary sexual characteristics GO:0045137 50 0.032
Worm
compound eye morphogenesis GO:0001745 249 0.032
columnar cuboidal epithelial cell development GO:0002066 249 0.032
Zebrafish
embryonic axis specification GO:0000578 107 0.032
histolysis GO:0007559 102 0.031
Fly
endocytosis GO:0006897 310 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.031
Zebrafish
neural retina development GO:0003407 4 0.031
peptidyl lysine acetylation GO:0018394 39 0.030
epithelial tube formation GO:0072175 7 0.030
production of molecular mediator of immune response GO:0002440 46 0.030
somatic stem cell maintenance GO:0035019 14 0.029
single organismal cell cell adhesion GO:0016337 45 0.029
cardioblast cell fate commitment GO:0042684 14 0.029
regulation of protein complex assembly GO:0043254 42 0.029
regulation of cellular amide metabolic process GO:0034248 39 0.029
positive regulation of signal transduction GO:0009967 223 0.029
Mouse
gland morphogenesis GO:0022612 145 0.028
limb morphogenesis GO:0035108 1 0.028
regulation of heart morphogenesis GO:2000826 3 0.028
Mouse
protein ubiquitination GO:0016567 70 0.028
regulation of actin filament based process GO:0032970 42 0.027
mesenchymal cell development GO:0014031 1 0.027
Mouse
development of primary male sexual characteristics GO:0046546 9 0.027
heart process GO:0003015 37 0.027
Zebrafish
muscle attachment GO:0016203 36 0.026
anterior head development GO:0097065 3 0.026
dendrite self avoidance GO:0070593 8 0.026
tissue homeostasis GO:0001894 36 0.026
peripheral nervous system development GO:0007422 52 0.026
Zebrafish Mouse
cellular amide metabolic process GO:0043603 80 0.026
single organism cellular localization GO:1902580 180 0.025
cellular macromolecular complex assembly GO:0034622 153 0.025
positive regulation of cell development GO:0010720 61 0.025
circadian rhythm GO:0007623 105 0.025
negative regulation of synapse assembly GO:0051964 39 0.025
protein transport GO:0015031 155 0.025
formation of organ boundary GO:0010160 30 0.025
notch signaling pathway GO:0007219 120 0.025
death GO:0016265 284 0.024
Mouse Fly
wound healing GO:0042060 75 0.024
modification dependent protein catabolic process GO:0019941 78 0.024
negative regulation of neurogenesis GO:0050768 53 0.024
Mouse
localization of cell GO:0051674 257 0.024
Mouse
establishment of protein localization GO:0045184 163 0.024
establishment of localization in cell GO:0051649 402 0.024
Rat
dorsal ventral axis specification GO:0009950 66 0.023
meiotic cell cycle GO:0051321 171 0.023
negative regulation of cell cycle GO:0045786 116 0.023
regulation of humoral immune response GO:0002920 51 0.023
negative regulation of cellular component organization GO:0051129 108 0.023
peptide biosynthetic process GO:0043043 42 0.023
regulation of behavior GO:0050795 75 0.023
regulation of epithelial cell migration open tracheal system GO:2000274 11 0.023
histone acetylation GO:0016573 38 0.023
chromosome organization GO:0051276 360 0.022
regulation of production of molecular mediator of immune response GO:0002700 44 0.022
regulation of axon guidance GO:1902667 10 0.022
regulation of sequence specific dna binding transcription factor activity GO:0051090 12 0.022
lamellipodium assembly GO:0030032 21 0.022
outflow tract morphogenesis GO:0003151 4 0.021
Mouse
posttranscriptional regulation of gene expression GO:0010608 145 0.021
gonad development GO:0008406 50 0.021
Worm
peptide metabolic process GO:0006518 80 0.021
ectodermal placode formation GO:0060788 4 0.021
positive regulation of cell morphogenesis involved in differentiation GO:0010770 12 0.021
nephron tubule formation GO:0072079 3 0.021
camera type eye development GO:0043010 4 0.021
immune response regulating signaling pathway GO:0002764 2 0.020
camera type eye morphogenesis GO:0048593 2 0.020
negative regulation of molecular function GO:0044092 51 0.020
developmental maturation GO:0021700 172 0.020
positive regulation of cell migration GO:0030335 2 0.019
cell adhesion GO:0007155 136 0.019
protein acylation GO:0043543 42 0.019
regulation of response to external stimulus GO:0032101 115 0.019
Mouse
aging GO:0007568 143 0.019
histone modification GO:0016570 106 0.018
negative regulation of wnt signaling pathway GO:0030178 28 0.018
Mouse
protein targeting GO:0006605 64 0.018
negative regulation of signal transduction GO:0009968 206 0.018
Mouse Rat
tube fusion GO:0035146 17 0.018
central nervous system segmentation GO:0035283 5 0.018
cellular catabolic process GO:0044248 372 0.018
regulation of axon extension GO:0030516 8 0.017
internal protein amino acid acetylation GO:0006475 38 0.017
anterior posterior axis specification embryo GO:0008595 103 0.017
striated muscle cell differentiation GO:0051146 90 0.017
Zebrafish
regulation of organelle organization GO:0033043 196 0.017
larval somatic muscle development GO:0007526 19 0.016
Fly
cell cell adhesion GO:0098609 26 0.016
ras protein signal transduction GO:0007265 88 0.016
negative regulation of neuron apoptotic process GO:0043524 14 0.016
Mouse
pigmentation GO:0043473 75 0.016
regulation of cell matrix adhesion GO:0001952 1 0.016
regulation of photoreceptor cell differentiation GO:0046532 34 0.016
dephosphorylation GO:0016311 51 0.016
gastrulation with mouth forming first GO:0001703 36 0.016
bmp signaling pathway GO:0030509 27 0.015
specification of organ identity GO:0010092 3 0.015
Human
amide biosynthetic process GO:0043604 42 0.015
substrate dependent cell migration GO:0006929 3 0.015
salivary gland development GO:0007431 162 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
regulation of antimicrobial peptide production GO:0002784 44 0.015
syncytium formation by plasma membrane fusion GO:0000768 43 0.015
tissue death GO:0016271 102 0.015
Fly
heart formation GO:0060914 6 0.015
Human Mouse
stress activated protein kinase signaling cascade GO:0031098 55 0.015
response to lithium ion GO:0010226 1 0.015
regulation of intracellular signal transduction GO:1902531 236 0.015
Mouse
protein localization GO:0008104 284 0.015
anterior commissure morphogenesis GO:0021960 2 0.015
regulation of embryonic development GO:0045995 68 0.014
protein acetylation GO:0006473 39 0.014
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.014
cellular protein complex assembly GO:0043623 71 0.014
negative regulation of cell death GO:0060548 81 0.014
Mouse
germ line stem cell division GO:0042078 25 0.014
negative regulation of apoptotic process GO:0043066 63 0.014
Mouse
central nervous system projection neuron axonogenesis GO:0021952 6 0.014
sensory perception of smell GO:0007608 80 0.014
response to hormone GO:0009725 45 0.014
Rat
immune effector process GO:0002252 98 0.013
establishment of body hair planar orientation GO:0048105 1 0.013
gliogenesis GO:0042063 80 0.013
protein complex biogenesis GO:0070271 201 0.013
neuron fate specification GO:0048665 12 0.013
Zebrafish Mouse
leg disc pattern formation GO:0035223 11 0.013
Fly
regulation of response to biotic stimulus GO:0002831 63 0.013
myotube differentiation GO:0014902 46 0.013
limb development GO:0060173 1 0.013
semaphorin plexin signaling pathway GO:0071526 4 0.013
chromatin organization GO:0006325 207 0.013
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.013
ubiquitin dependent protein catabolic process GO:0006511 78 0.013
axon extension GO:0048675 32 0.013
Zebrafish
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.012
proximal distal pattern formation imaginal disc GO:0007449 11 0.012
Fly
female sex differentiation GO:0046660 20 0.012
regulation of cytoskeleton organization GO:0051493 89 0.012
trunk segmentation GO:0035290 8 0.012
positive regulation of cell motility GO:2000147 3 0.012
cell fate commitment involved in formation of primary germ layer GO:0060795 10 0.012
wnt signaling pathway GO:0016055 98 0.012
Mouse
regulation of cell proliferation GO:0042127 163 0.012
Mouse
locomotory behavior GO:0007626 176 0.012
positive regulation of molecular function GO:0044093 136 0.012
Mouse
cellular component assembly involved in morphogenesis GO:0010927 151 0.012
internal peptidyl lysine acetylation GO:0018393 38 0.012
regulation of cell projection organization GO:0031344 92 0.012
imaginal disc derived wing hair organization GO:0035317 45 0.012
negative regulation of epithelial cell proliferation GO:0050680 4 0.011
skin development GO:0043588 65 0.011
regulation of locomotion GO:0040012 42 0.011
axon midline choice point recognition GO:0016199 26 0.011
protein localization to nucleus GO:0034504 55 0.011
female genitalia development GO:0030540 6 0.011
organ formation GO:0048645 39 0.011
Human Mouse
convergent extension GO:0060026 2 0.011
proximal distal pattern formation GO:0009954 15 0.011
Fly
apoptotic process involved in development GO:1902742 20 0.011
neuroblast fate commitment GO:0014017 19 0.011
regulation of protein deacetylation GO:0090311 2 0.011
organic substance transport GO:0071702 257 0.011
Rat
cellular response to oxygen containing compound GO:1901701 79 0.011
neuromuscular junction development GO:0007528 149 0.011
positive regulation of cell proliferation GO:0008284 47 0.011
Mouse
chitin based cuticle sclerotization GO:0007593 19 0.011
eggshell formation GO:0030703 105 0.011
male courtship behavior GO:0008049 63 0.011
intracellular protein transport GO:0006886 104 0.011
antimicrobial peptide biosynthetic process GO:0002777 38 0.011
embryonic organ development GO:0048568 50 0.011
positive regulation of response to external stimulus GO:0032103 44 0.011
actin filament polymerization GO:0030041 27 0.011
single organism cell adhesion GO:0098602 47 0.011
multi organism behavior GO:0051705 175 0.011
regulation of imaginal disc derived wing size GO:0044719 20 0.011
developmental cell growth GO:0048588 52 0.010
Zebrafish
response to organic substance GO:0010033 284 0.010
Rat
negative regulation of transforming growth factor beta receptor signaling pathway GO:0030512 4 0.010
response to endogenous stimulus GO:0009719 119 0.010
Rat
negative regulation of neuron differentiation GO:0045665 16 0.010
Mouse
immune system development GO:0002520 57 0.010
vesicle mediated transport GO:0016192 381 0.010
polarized epithelial cell differentiation GO:0030859 10 0.010
regulation of notch signaling pathway GO:0008593 100 0.010
negative regulation of axon extension GO:0030517 3 0.010
positive regulation of axon guidance GO:1902669 1 0.010
sleep GO:0030431 49 0.010
g1 s transition of mitotic cell cycle GO:0000082 31 0.010
enteroendocrine cell differentiation GO:0035883 1 0.010
Zebrafish
myoblast fusion GO:0007520 43 0.010
dendritic spine development GO:0060996 4 0.010
aggressive behavior GO:0002118 63 0.010
positive regulation of translation GO:0045727 12 0.010

tup disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.262
congenital heart disease DOID:1682 0 0.141
tetralogy of fallot DOID:6419 0 0.141
heart disease DOID:114 0 0.141
cardiovascular system disease DOID:1287 0 0.141
nervous system disease DOID:863 0 0.032
immune system disease DOID:2914 0 0.011
sensory system disease DOID:0050155 0 0.011
eye and adnexa disease DOID:1492 0 0.011
auditory system disease DOID:2742 0 0.011
autosomal dominant nonsyndromic deafness DOID:0050564 0 0.011
nonsyndromic deafness DOID:0050563 0 0.011