Drosophila melanogaster

28 known processes

Pcmt (Dmel_CG2152)

Protein-L-isoaspartate (D-aspartate) O-methyltransferase

(Aliases: Pimt,pcmt,PIMT,CG2152,Dmel\CG2152,dPIMT)

Pcmt biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
determination of adult lifespan GO:0008340 137 0.134
aging GO:0007568 143 0.119
cellular catabolic process GO:0044248 372 0.106
organic substance catabolic process GO:1901575 308 0.083
regulation of protein metabolic process GO:0051246 256 0.079
multicellular organismal aging GO:0010259 140 0.078
response to oxygen containing compound GO:1901700 200 0.075
negative regulation of cell communication GO:0010648 223 0.073
catabolic process GO:0009056 409 0.070
single organism catabolic process GO:0044712 228 0.070
defense response to other organism GO:0098542 225 0.065
response to nitrogen compound GO:1901698 90 0.062
organonitrogen compound metabolic process GO:1901564 318 0.062
defense response GO:0006952 300 0.058
small molecule metabolic process GO:0044281 305 0.055
response to biotic stimulus GO:0009607 294 0.052
defense response to bacterium GO:0042742 178 0.052
enzyme linked receptor protein signaling pathway GO:0007167 179 0.051
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.050
appendage morphogenesis GO:0035107 397 0.049
negative regulation of growth GO:0045926 84 0.049
negative regulation of signaling GO:0023057 219 0.047
negative regulation of response to stimulus GO:0048585 258 0.045
response to endogenous stimulus GO:0009719 119 0.044
response to organic substance GO:0010033 284 0.044
oxidation reduction process GO:0055114 123 0.040
negative regulation of signal transduction GO:0009968 206 0.040
appendage development GO:0048736 401 0.039
response to reactive oxygen species GO:0000302 24 0.038
response to external biotic stimulus GO:0043207 293 0.037
cellular protein modification process GO:0006464 438 0.037
cellular response to peptide hormone stimulus GO:0071375 28 0.037
endocytosis GO:0006897 310 0.036
imaginal disc derived appendage development GO:0048737 399 0.036
regulation of growth GO:0040008 233 0.036
macromolecule catabolic process GO:0009057 161 0.036
response to nutrient levels GO:0031667 114 0.035
positive regulation of signaling GO:0023056 243 0.035
positive regulation of signal transduction GO:0009967 223 0.035
negative regulation of cellular metabolic process GO:0031324 382 0.035
wing disc morphogenesis GO:0007472 344 0.034
imaginal disc derived appendage morphogenesis GO:0035114 395 0.034
negative regulation of developmental process GO:0051093 201 0.033
post embryonic appendage morphogenesis GO:0035120 385 0.032
growth GO:0040007 359 0.032
carbohydrate derivative metabolic process GO:1901135 217 0.032
regulation of cellular catabolic process GO:0031329 157 0.031
cellular macromolecule catabolic process GO:0044265 136 0.031
regionalization GO:0003002 416 0.031
single organism cellular localization GO:1902580 180 0.031
proteolysis GO:0006508 192 0.030
regulation of catabolic process GO:0009894 170 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
regulation of cell death GO:0010941 173 0.029
ribonucleoside metabolic process GO:0009119 127 0.029
nucleotide metabolic process GO:0009117 161 0.029
response to other organism GO:0051707 293 0.028
protein catabolic process GO:0030163 101 0.028
response to bacterium GO:0009617 198 0.028
columnar cuboidal epithelial cell development GO:0002066 249 0.028
phagocytosis GO:0006909 215 0.027
negative regulation of nucleic acid templated transcription GO:1903507 240 0.027
regulation of multicellular organismal development GO:2000026 414 0.027
nucleobase containing small molecule metabolic process GO:0055086 174 0.027
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.026
regulation of developmental growth GO:0048638 174 0.026
cellular response to extracellular stimulus GO:0031668 64 0.025
positive regulation of macromolecule metabolic process GO:0010604 405 0.025
regulation of cellular protein metabolic process GO:0032268 243 0.025
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
response to organonitrogen compound GO:0010243 75 0.024
positive regulation of cell communication GO:0010647 250 0.024
negative regulation of intracellular signal transduction GO:1902532 57 0.023
positive regulation of response to stimulus GO:0048584 323 0.023
purine containing compound metabolic process GO:0072521 155 0.023
nucleoside phosphate metabolic process GO:0006753 162 0.023
epithelial cell development GO:0002064 274 0.023
protein modification process GO:0036211 438 0.023
vesicle mediated transport GO:0016192 381 0.022
nucleoside metabolic process GO:0009116 127 0.022
cell death GO:0008219 279 0.022
carbohydrate derivative catabolic process GO:1901136 118 0.022
organophosphate metabolic process GO:0019637 195 0.022
nicotinamide nucleotide metabolic process GO:0046496 2 0.022
organonitrogen compound catabolic process GO:1901565 128 0.021
phosphorylation GO:0016310 294 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
response to hydrogen peroxide GO:0042542 11 0.021
nucleoside triphosphate metabolic process GO:0009141 120 0.021
cellular response to dna damage stimulus GO:0006974 223 0.021
aromatic compound catabolic process GO:0019439 166 0.021
energy derivation by oxidation of organic compounds GO:0015980 32 0.021
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.021
negative regulation of protein metabolic process GO:0051248 85 0.021
establishment of localization in cell GO:0051649 402 0.020
programmed cell death GO:0012501 257 0.020
regulation of programmed cell death GO:0043067 152 0.020
regulation of cell cycle GO:0051726 291 0.020
cellular response to nitrogen compound GO:1901699 51 0.020
cellular response to insulin stimulus GO:0032869 28 0.020
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.020
intracellular signal transduction GO:0035556 300 0.019
embryonic pattern specification GO:0009880 174 0.019
oxoacid metabolic process GO:0043436 103 0.019
respiratory system development GO:0060541 213 0.019
immune system process GO:0002376 347 0.019
regulation of intracellular signal transduction GO:1902531 236 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
negative regulation of gene expression GO:0010629 387 0.019
death GO:0016265 284 0.019
single organism biosynthetic process GO:0044711 206 0.019
actin cytoskeleton organization GO:0030036 206 0.019
regulation of response to stress GO:0080134 200 0.019
heterocycle catabolic process GO:0046700 166 0.019
regulation of apoptotic process GO:0042981 130 0.019
organelle fission GO:0048285 340 0.018
purine nucleoside metabolic process GO:0042278 127 0.018
cellular amino acid metabolic process GO:0006520 61 0.018
posttranscriptional regulation of gene expression GO:0010608 145 0.018
response to extracellular stimulus GO:0009991 116 0.018
regulation of proteolysis GO:0030162 87 0.018
ovarian follicle cell development GO:0030707 248 0.018
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.018
regulation of nervous system development GO:0051960 248 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
regulation of cell differentiation GO:0045595 302 0.018
gland development GO:0048732 191 0.018
ribonucleotide metabolic process GO:0009259 145 0.018
immune response regulating signaling pathway GO:0002764 2 0.018
meiotic cell cycle GO:0051321 171 0.018
cellular response to organic substance GO:0071310 132 0.018
regulation of cellular component biogenesis GO:0044087 201 0.018
cellular protein catabolic process GO:0044257 83 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.017
negative regulation of cellular biosynthetic process GO:0031327 277 0.017
centrosome cycle GO:0007098 137 0.017
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.017
carboxylic acid metabolic process GO:0019752 92 0.017
response to abiotic stimulus GO:0009628 341 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
positive regulation of cellular biosynthetic process GO:0031328 316 0.017
macromolecular complex assembly GO:0065003 256 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
immune response GO:0006955 246 0.017
positive regulation of protein metabolic process GO:0051247 128 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
regulation of insulin receptor signaling pathway GO:0046626 17 0.017
response to insulin GO:0032868 29 0.016
protein complex assembly GO:0006461 200 0.016
glycosyl compound metabolic process GO:1901657 127 0.016
epithelial cell migration GO:0010631 148 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.016
regulation of translation GO:0006417 56 0.016
organic substance transport GO:0071702 257 0.016
cellular protein complex assembly GO:0043623 71 0.016
autophagy GO:0006914 108 0.016
purine ribonucleotide metabolic process GO:0009150 145 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
ribose phosphate metabolic process GO:0019693 145 0.016
protein complex biogenesis GO:0070271 201 0.015
cellular amine metabolic process GO:0044106 12 0.015
regulation of molecular function GO:0065009 217 0.015
protein maturation GO:0051604 71 0.015
carbohydrate metabolic process GO:0005975 82 0.015
response to lipopolysaccharide GO:0032496 4 0.015
cellular response to endogenous stimulus GO:0071495 80 0.015
cell growth GO:0016049 108 0.015
protein modification by small protein conjugation or removal GO:0070647 106 0.015
response to hormone GO:0009725 45 0.015
purine nucleoside triphosphate metabolic process GO:0009144 119 0.015
negative regulation of biosynthetic process GO:0009890 277 0.015
homeostatic process GO:0042592 199 0.015
organelle localization GO:0051640 148 0.015
nucleoside catabolic process GO:0009164 112 0.014
endomembrane system organization GO:0010256 119 0.014
pyridine containing compound metabolic process GO:0072524 3 0.014
purine nucleoside triphosphate catabolic process GO:0009146 108 0.014
amine metabolic process GO:0009308 12 0.014
regulation of mitotic cell cycle GO:0007346 190 0.014
generation of precursor metabolites and energy GO:0006091 42 0.014
spindle organization GO:0007051 253 0.014
nitrogen compound transport GO:0071705 85 0.014
chromosome organization GO:0051276 360 0.014
chemotaxis GO:0006935 249 0.014
cellular response to starvation GO:0009267 61 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
intracellular transport GO:0046907 228 0.014
cell cycle phase transition GO:0044770 140 0.013
regulation of catalytic activity GO:0050790 185 0.013
cellular response to oxygen containing compound GO:1901701 79 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
mitochondrion organization GO:0007005 65 0.013
response to organic cyclic compound GO:0014070 89 0.013
immune response activating signal transduction GO:0002757 2 0.013
hormone catabolic process GO:0042447 3 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
negative regulation of multicellular organismal process GO:0051241 142 0.013
nuclear division GO:0000280 332 0.013
response to oxidative stress GO:0006979 86 0.013
nucleobase containing compound catabolic process GO:0034655 165 0.013
purine ribonucleoside catabolic process GO:0046130 112 0.013
purine nucleoside catabolic process GO:0006152 112 0.013
cellular response to reactive oxygen species GO:0034614 14 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
feeding behavior GO:0007631 50 0.013
negative regulation of cell death GO:0060548 81 0.012
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.012
protein phosphorylation GO:0006468 169 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
hydrogen peroxide catabolic process GO:0042744 6 0.012
positive regulation of catabolic process GO:0009896 105 0.012
organic acid metabolic process GO:0006082 103 0.012
cell motility GO:0048870 251 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
spinal cord development GO:0021510 1 0.012
cell migration GO:0016477 238 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
lipid homeostasis GO:0055088 33 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
cellular response to external stimulus GO:0071496 66 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
morphogenesis of an epithelium GO:0002009 276 0.012
regulation of immune response GO:0050776 118 0.012
developmental growth GO:0048589 280 0.011
sensory organ morphogenesis GO:0090596 260 0.011
axis specification GO:0009798 167 0.011
nucleotide catabolic process GO:0009166 109 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
proteasomal protein catabolic process GO:0010498 59 0.011
gtp catabolic process GO:0006184 72 0.011
cation transport GO:0006812 110 0.011
protein modification by small protein conjugation GO:0032446 79 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
regulation of cell cycle phase transition GO:1901987 130 0.011
compound eye development GO:0048749 307 0.011
forebrain development GO:0030900 2 0.011
locomotory behavior GO:0007626 176 0.011
response to radiation GO:0009314 155 0.011
modification dependent protein catabolic process GO:0019941 78 0.011
regulation of phosphorylation GO:0042325 147 0.011
camera type eye development GO:0043010 4 0.011
regulation of cellular amine metabolic process GO:0033238 3 0.011
protein processing GO:0016485 68 0.011
tripartite regional subdivision GO:0007351 103 0.011
response to ionizing radiation GO:0010212 32 0.011
positive regulation of developmental process GO:0051094 143 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
regulation of cellular response to insulin stimulus GO:1900076 17 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
mitotic dna integrity checkpoint GO:0044774 75 0.011
ribonucleoside catabolic process GO:0042454 112 0.011
purine containing compound catabolic process GO:0072523 112 0.011
cellular protein localization GO:0034613 160 0.011
cellular response to oxidative stress GO:0034599 28 0.011
gtp metabolic process GO:0046039 72 0.011
microtubule organizing center organization GO:0031023 168 0.010
single organism intracellular transport GO:1902582 207 0.010
insulin receptor signaling pathway GO:0008286 25 0.010
mitotic spindle organization GO:0007052 220 0.010
eye development GO:0001654 323 0.010
organophosphate catabolic process GO:0046434 112 0.010
cytoplasmic transport GO:0016482 130 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
positive regulation of hydrolase activity GO:0051345 78 0.010
negative regulation of programmed cell death GO:0043069 72 0.010
regulation of innate immune response GO:0045088 71 0.010
cellular macromolecule localization GO:0070727 220 0.010
regulation of ras protein signal transduction GO:0046578 93 0.010
cellular response to hydrogen peroxide GO:0070301 7 0.010
regulation of protein modification process GO:0031399 112 0.010
regulation of immune system process GO:0002682 176 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
cellular response to peptide GO:1901653 28 0.010

Pcmt disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.011
nervous system disease DOID:863 0 0.011
disease of metabolism DOID:0014667 0 0.010