Drosophila melanogaster

193 known processes

Vps25 (Dmel_CG14750)

Vacuolar protein sorting 25

(Aliases: CG14750,Dmel\CG14750,l(2)44Db,VPS25,dVps25,l(2)k08904,vps25,ESCRT-I,ESCRT-II)

Vps25 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
germarium derived female germ line cyst formation GO:0030727 42 0.996
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathway GO:0043162 8 0.995
germarium derived egg chamber formation GO:0007293 101 0.993
endosome transport via multivesicular body sorting pathway GO:0032509 12 0.991
female germ line cyst formation GO:0048135 42 0.989
germ line cyst formation GO:0048134 44 0.954
ovarian follicle cell development GO:0030707 248 0.947
ovarian follicle cell stalk formation GO:0030713 17 0.941
regulation of notch signaling pathway GO:0008593 100 0.861
single organism membrane fusion GO:0044801 42 0.798
regulation of epidermal growth factor receptor signaling pathway GO:0042058 42 0.778
regulation of erbb signaling pathway GO:1901184 42 0.769
membrane organization GO:0061024 112 0.674
endosomal transport GO:0016197 44 0.621
cell proliferation GO:0008283 299 0.543
columnar cuboidal epithelial cell development GO:0002066 249 0.526
positive regulation of cellular component organization GO:0051130 156 0.510
erbb signaling pathway GO:0038127 58 0.447
morphogenesis of follicular epithelium GO:0016333 36 0.439
epithelial cell differentiation GO:0030855 322 0.433
protein modification by small protein conjugation or removal GO:0070647 106 0.423
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.415
regionalization GO:0003002 416 0.389
ubiquitin dependent protein catabolic process GO:0006511 78 0.384
protein catabolic process GO:0030163 101 0.377
single organism cellular localization GO:1902580 180 0.369
Yeast
negative regulation of erbb signaling pathway GO:1901185 29 0.331
regulation of immune response GO:0050776 118 0.317
regulation of apoptotic process GO:0042981 130 0.316
protein ubiquitination GO:0016567 70 0.307
cell death GO:0008219 279 0.301
modification dependent protein catabolic process GO:0019941 78 0.291
blastoderm segmentation GO:0007350 159 0.278
notch signaling pathway GO:0007219 120 0.278
immune system process GO:0002376 347 0.255
enzyme linked receptor protein signaling pathway GO:0007167 179 0.253
negative regulation of signal transduction GO:0009968 206 0.230
vesicle mediated transport GO:0016192 381 0.229
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.226
oocyte development GO:0048599 124 0.225
membrane budding GO:0006900 4 0.223
regulation of response to stress GO:0080134 200 0.215
axis specification GO:0009798 167 0.188
negative regulation of response to stimulus GO:0048585 258 0.187
regulation of cell cycle phase transition GO:1901987 130 0.184
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.184
single organism membrane organization GO:0044802 93 0.181
regulation of cell proliferation GO:0042127 163 0.177
compound eye development GO:0048749 307 0.177
autophagy GO:0006914 108 0.176
purine ribonucleoside metabolic process GO:0046128 127 0.160
death GO:0016265 284 0.158
vacuolar transport GO:0007034 13 0.154
Yeast
response to extracellular stimulus GO:0009991 116 0.154
cytoplasmic transport GO:0016482 130 0.139
Yeast
glycosyl compound metabolic process GO:1901657 127 0.139
nucleoside metabolic process GO:0009116 127 0.139
organelle membrane fusion GO:0090174 16 0.138
negative regulation of gene expression GO:0010629 387 0.135
Yeast
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.135
Yeast
developmental maturation GO:0021700 172 0.133
reproductive structure development GO:0048608 74 0.130
epidermal growth factor receptor signaling pathway GO:0007173 58 0.127
cellular macromolecule localization GO:0070727 220 0.126
Yeast
cellular macromolecule catabolic process GO:0044265 136 0.126
regulation of cellular catabolic process GO:0031329 157 0.121
anterior posterior pattern specification GO:0009952 136 0.120
regulation of cell cycle GO:0051726 291 0.118
positive regulation of macromolecule metabolic process GO:0010604 405 0.114
vesicle organization GO:0016050 44 0.114
morphogenesis of an epithelium GO:0002009 276 0.113
organelle fusion GO:0048284 46 0.113
positive regulation of response to stimulus GO:0048584 323 0.112
cellular protein catabolic process GO:0044257 83 0.111
segmentation GO:0035282 207 0.110
modification dependent macromolecule catabolic process GO:0043632 79 0.109
regulation of innate immune response GO:0045088 71 0.108
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.108
aging GO:0007568 143 0.107
multicellular organismal aging GO:0010259 140 0.106
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.106
intracellular transport GO:0046907 228 0.103
regulation of cell death GO:0010941 173 0.102
organelle assembly GO:0070925 198 0.101
organic substance catabolic process GO:1901575 308 0.098
oocyte construction GO:0007308 112 0.098
single organism membrane budding GO:1902591 2 0.097
protein modification by small protein conjugation GO:0032446 79 0.094
regulation of programmed cell death GO:0043067 152 0.091
negative regulation of cell communication GO:0010648 223 0.090
protein modification process GO:0036211 438 0.089
epithelial cell development GO:0002064 274 0.089
programmed cell death GO:0012501 257 0.086
small molecule metabolic process GO:0044281 305 0.083
cell cycle phase transition GO:0044770 140 0.083
endocytosis GO:0006897 310 0.082
endomembrane system organization GO:0010256 119 0.082
establishment or maintenance of cell polarity GO:0007163 167 0.081
protein localization GO:0008104 284 0.080
negative regulation of epithelial cell proliferation GO:0050680 4 0.080
negative regulation of signaling GO:0023057 219 0.078
determination of adult lifespan GO:0008340 137 0.077
regulation of multi organism process GO:0043900 131 0.076
reproductive system development GO:0061458 74 0.074
molting cycle GO:0042303 56 0.074
sex differentiation GO:0007548 81 0.074
embryo development ending in birth or egg hatching GO:0009792 152 0.069
ribonucleoside triphosphate metabolic process GO:0009199 119 0.065
macromolecule catabolic process GO:0009057 161 0.062
cell motility GO:0048870 251 0.062
apoptotic process GO:0006915 159 0.061
endosomal vesicle fusion GO:0034058 4 0.060
protein complex biogenesis GO:0070271 201 0.059
cellular protein localization GO:0034613 160 0.058
Yeast
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.058
Yeast
photoreceptor cell differentiation GO:0046530 170 0.058
purine nucleoside metabolic process GO:0042278 127 0.057
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.055
body morphogenesis GO:0010171 2 0.055
establishment of localization in cell GO:0051649 402 0.054
protein complex assembly GO:0006461 200 0.053
positive regulation of cellular biosynthetic process GO:0031328 316 0.052
catabolic process GO:0009056 409 0.050
transcription from rna polymerase ii promoter GO:0006366 368 0.050
Yeast
regulation of organelle organization GO:0033043 196 0.050
regulation of epithelial cell proliferation GO:0050678 4 0.050
response to nutrient levels GO:0031667 114 0.049
carbohydrate derivative metabolic process GO:1901135 217 0.048
positive regulation of cellular protein metabolic process GO:0032270 118 0.048
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.047
regulation of phosphate metabolic process GO:0019220 210 0.046
macromolecular complex assembly GO:0065003 256 0.045
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.045
proteolysis GO:0006508 192 0.045
regulation of mitotic cell cycle GO:0007346 190 0.044
nucleoside phosphate metabolic process GO:0006753 162 0.044
anterior posterior axis specification GO:0009948 109 0.044
purine nucleoside triphosphate metabolic process GO:0009144 119 0.044
cellularization GO:0007349 90 0.044
protein transport GO:0015031 155 0.043
cell adhesion GO:0007155 136 0.043
cellular catabolic process GO:0044248 372 0.043
negative regulation of biosynthetic process GO:0009890 277 0.042
Yeast
cell division GO:0051301 248 0.042
carbohydrate derivative biosynthetic process GO:1901137 85 0.040
phosphorylation GO:0016310 294 0.040
regulation of molecular function GO:0065009 217 0.039
regulation of cellular protein metabolic process GO:0032268 243 0.039
positive regulation of biosynthetic process GO:0009891 316 0.039
single organism intracellular transport GO:1902582 207 0.038
axon development GO:0061564 297 0.038
mrna processing GO:0006397 104 0.038
regulation of cell shape GO:0008360 113 0.037
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.037
Yeast
negative regulation of cell proliferation GO:0008285 69 0.035
regulation of anatomical structure morphogenesis GO:0022603 242 0.035
regulation of cell cycle process GO:0010564 181 0.035
oocyte differentiation GO:0009994 145 0.034
purine ribonucleotide metabolic process GO:0009150 145 0.034
response to starvation GO:0042594 97 0.034
cellular protein modification process GO:0006464 438 0.034
pole plasm oskar mrna localization GO:0045451 46 0.034
cellular protein complex assembly GO:0043623 71 0.034
development of primary sexual characteristics GO:0045137 50 0.034
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.034
Yeast
negative regulation of apoptotic process GO:0043066 63 0.033
germarium derived oocyte differentiation GO:0030706 29 0.033
protein secretion GO:0009306 45 0.033
axonogenesis GO:0007409 290 0.033
negative regulation of cellular metabolic process GO:0031324 382 0.032
Yeast
purine containing compound metabolic process GO:0072521 155 0.032
regulation of protein metabolic process GO:0051246 256 0.032
defense response GO:0006952 300 0.031
positive regulation of cell communication GO:0010647 250 0.031
autophagic vacuole fusion GO:0000046 15 0.031
cellular ketone metabolic process GO:0042180 24 0.031
regulation of localization GO:0032879 275 0.031
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.031
positive regulation of rna biosynthetic process GO:1902680 266 0.031
immune response GO:0006955 246 0.031
eye development GO:0001654 323 0.030
ribose phosphate metabolic process GO:0019693 145 0.030
embryonic pattern specification GO:0009880 174 0.030
cuticle development GO:0042335 86 0.029
regulation of immune system process GO:0002682 176 0.029
positive regulation of signal transduction GO:0009967 223 0.029
negative regulation of mitotic cell cycle GO:0045930 109 0.029
regulation of phosphorus metabolic process GO:0051174 210 0.029
negative regulation of notch signaling pathway GO:0045746 41 0.029
single organism catabolic process GO:0044712 228 0.028
oocyte axis specification GO:0007309 108 0.028
oocyte anterior posterior axis specification GO:0007314 72 0.028
homeostatic process GO:0042592 199 0.027
compound eye morphogenesis GO:0001745 249 0.027
regulation of microtubule based process GO:0032886 49 0.027
regulation of cellular localization GO:0060341 136 0.027
germarium derived oocyte fate determination GO:0007294 26 0.026
response to bacterium GO:0009617 198 0.026
positive regulation of immune response GO:0050778 63 0.026
defense response to gram negative bacterium GO:0050829 94 0.026
camera type eye development GO:0043010 4 0.025
organonitrogen compound metabolic process GO:1901564 318 0.025
smoothened signaling pathway GO:0007224 49 0.025
positive regulation of signaling GO:0023056 243 0.025
cell projection assembly GO:0030031 94 0.025
regulation of dna templated transcription elongation GO:0032784 17 0.025
early endosome to late endosome transport GO:0045022 3 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.024
notch receptor processing GO:0007220 13 0.024
male gamete generation GO:0048232 201 0.024
regulation of intracellular signal transduction GO:1902531 236 0.024
intracellular mrna localization involved in pattern specification process GO:0060810 56 0.024
defense response to bacterium GO:0042742 178 0.024
positive regulation of apoptotic process GO:0043065 47 0.024
positive regulation of cell death GO:0010942 69 0.024
mitotic cell cycle phase transition GO:0044772 138 0.023
purine containing compound catabolic process GO:0072523 112 0.023
protein localization to organelle GO:0033365 82 0.023
Yeast
regulation of symbiosis encompassing mutualism through parasitism GO:0043903 15 0.023
regulation of protein modification process GO:0031399 112 0.023
mrna splicing via spliceosome GO:0000398 73 0.023
regulation of cell differentiation GO:0045595 302 0.022
eye morphogenesis GO:0048592 260 0.022
positive regulation of transcription dna templated GO:0045893 266 0.022
regulation of protein ubiquitination GO:0031396 22 0.022
regulation of cellular component size GO:0032535 98 0.022
organophosphate metabolic process GO:0019637 195 0.022
oocyte microtubule cytoskeleton organization GO:0016325 35 0.021
imaginal disc pattern formation GO:0007447 91 0.021
cell maturation GO:0048469 144 0.021
regulation of autophagy GO:0010506 62 0.021
innate immune response GO:0045087 144 0.021
regulation of catalytic activity GO:0050790 185 0.021
dna templated transcription elongation GO:0006354 18 0.021
ribonucleotide metabolic process GO:0009259 145 0.021
anatomical structure homeostasis GO:0060249 97 0.020
cation transport GO:0006812 110 0.020
regulation of protein modification by small protein conjugation or removal GO:1903320 25 0.020
proteasomal protein catabolic process GO:0010498 59 0.020
retina development in camera type eye GO:0060041 4 0.020
regulation of catabolic process GO:0009894 170 0.020
asymmetric protein localization GO:0008105 33 0.020
cellular response to extracellular stimulus GO:0031668 64 0.020
cellular macromolecular complex assembly GO:0034622 153 0.020
protein localization to membrane GO:0072657 19 0.020
instar larval development GO:0002168 55 0.019
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.019
negative regulation of programmed cell death GO:0043069 72 0.019
positive regulation of organelle organization GO:0010638 65 0.019
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.019
larval development GO:0002164 104 0.018
growth GO:0040007 359 0.018
embryonic hemopoiesis GO:0035162 26 0.018
membrane fusion GO:0061025 42 0.018
positive regulation of programmed cell death GO:0043068 62 0.018
cellular response to starvation GO:0009267 61 0.017
dendrite morphogenesis GO:0048813 199 0.017
lipid metabolic process GO:0006629 121 0.017
cellular response to dna damage stimulus GO:0006974 223 0.017
atp metabolic process GO:0046034 49 0.017
regulation of nervous system development GO:0051960 248 0.017
embryonic morphogenesis GO:0048598 206 0.017
establishment of protein localization to organelle GO:0072594 62 0.017
Yeast
cellular response to nutrient levels GO:0031669 62 0.017
negative regulation of cell death GO:0060548 81 0.017
compound eye photoreceptor cell differentiation GO:0001751 140 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
positive regulation of molecular function GO:0044093 136 0.017
regulation of cell morphogenesis GO:0022604 163 0.016
negative regulation of molecular function GO:0044092 51 0.016
chemotaxis GO:0006935 249 0.016
ribonucleoside metabolic process GO:0009119 127 0.016
ribonucleoside triphosphate catabolic process GO:0009203 108 0.016
ion transport GO:0006811 145 0.015
ovarian follicle cell migration GO:0007297 121 0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.015
cellular response to external stimulus GO:0071496 66 0.015
response to organic substance GO:0010033 284 0.015
gonad development GO:0008406 50 0.015
positive regulation of rna metabolic process GO:0051254 271 0.015
autophagic vacuole assembly GO:0000045 2 0.014
tripartite regional subdivision GO:0007351 103 0.014
positive regulation of gene expression GO:0010628 290 0.014
positive regulation of protein metabolic process GO:0051247 128 0.014
positive regulation of protein modification process GO:0031401 58 0.014
pole plasm rna localization GO:0007316 52 0.014
negative regulation of growth GO:0045926 84 0.014
cell growth GO:0016049 108 0.013
mitotic nuclear division GO:0007067 213 0.013
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
response to organic cyclic compound GO:0014070 89 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
positive regulation of phosphate metabolic process GO:0045937 139 0.013
maintenance of cell polarity GO:0030011 18 0.013
regulation of proteolysis GO:0030162 87 0.013
regulation of neuron differentiation GO:0045664 103 0.013
interspecies interaction between organisms GO:0044419 16 0.013
positive regulation of phosphorus metabolic process GO:0010562 139 0.013
eye photoreceptor cell differentiation GO:0001754 145 0.013
phagocytosis GO:0006909 215 0.012
regulation of cellular component biogenesis GO:0044087 201 0.012
guanosine containing compound catabolic process GO:1901069 74 0.012
production of small rna involved in gene silencing by rna GO:0070918 15 0.012
appendage development GO:0048736 401 0.012
ncrna metabolic process GO:0034660 43 0.012
purine nucleotide metabolic process GO:0006163 146 0.012
regulation of anatomical structure size GO:0090066 163 0.012
wing disc morphogenesis GO:0007472 344 0.012
negative regulation of multicellular organismal process GO:0051241 142 0.012
membrane protein proteolysis GO:0033619 6 0.012
intracellular protein transport GO:0006886 104 0.012
Yeast
organelle fission GO:0048285 340 0.012
scf dependent proteasomal ubiquitin dependent protein catabolic process GO:0031146 1 0.012
nucleoside monophosphate metabolic process GO:0009123 52 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.012
rna processing GO:0006396 147 0.011
symbiosis encompassing mutualism through parasitism GO:0044403 16 0.011
defense response to other organism GO:0098542 225 0.011
histone modification GO:0016570 106 0.011
oocyte fate determination GO:0030716 27 0.011
imaginal disc derived appendage development GO:0048737 399 0.011
mapk cascade GO:0000165 107 0.011
regulation of phosphorylation GO:0042325 147 0.011
tissue morphogenesis GO:0048729 297 0.011
positive regulation of nucleic acid templated transcription GO:1903508 266 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
mitotic cytokinesis GO:0000281 50 0.011
cell migration GO:0016477 238 0.011
regulation of cell development GO:0060284 215 0.011
establishment of protein localization GO:0045184 163 0.011
peptidyl lysine modification GO:0018205 57 0.011
maintenance of location GO:0051235 73 0.011
organophosphate catabolic process GO:0046434 112 0.011
nucleoside triphosphate metabolic process GO:0009141 120 0.011
endosome organization GO:0007032 9 0.011
signal transduction by phosphorylation GO:0023014 107 0.011
dsrna fragmentation GO:0031050 15 0.010
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.010
post embryonic appendage morphogenesis GO:0035120 385 0.010
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
organonitrogen compound biosynthetic process GO:1901566 117 0.010

Vps25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012