Drosophila melanogaster

61 known processes

Nup50 (Dmel_CG2158)

Nucleoporin 50

(Aliases: CG2158,Dmel\CG2158)

Nup50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic cell cycle phase transition GO:0044772 138 0.837
regulation of cell cycle GO:0051726 291 0.779
mitotic spindle organization GO:0007052 220 0.701
mitotic dna integrity checkpoint GO:0044774 75 0.560
mitotic cell cycle checkpoint GO:0007093 88 0.549
embryo development ending in birth or egg hatching GO:0009792 152 0.528
cellular protein modification process GO:0006464 438 0.447
negative regulation of mitotic cell cycle GO:0045930 109 0.410
cell cycle checkpoint GO:0000075 95 0.376
negative regulation of cell cycle phase transition GO:1901988 103 0.341
regulation of cell cycle process GO:0010564 181 0.317
protein modification process GO:0036211 438 0.309
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.307
protein complex assembly GO:0006461 200 0.307
mitotic dna damage checkpoint GO:0044773 74 0.302
regulation of mitotic cell cycle GO:0007346 190 0.277
mrna metabolic process GO:0016071 124 0.253
regulation of mitotic cell cycle phase transition GO:1901990 130 0.232
cell cycle phase transition GO:0044770 140 0.227
regulation of cell cycle phase transition GO:1901987 130 0.216
nucleobase containing compound catabolic process GO:0034655 165 0.211
regulation of cellular protein metabolic process GO:0032268 243 0.199
nuclear division GO:0000280 332 0.195
vesicle mediated transport GO:0016192 381 0.192
macromolecular complex assembly GO:0065003 256 0.187
cell proliferation GO:0008283 299 0.176
negative regulation of cell cycle process GO:0010948 109 0.167
mitotic g2 m transition checkpoint GO:0044818 70 0.166
purine containing compound metabolic process GO:0072521 155 0.165
protein transport GO:0015031 155 0.151
enzyme linked receptor protein signaling pathway GO:0007167 179 0.146
cell division GO:0051301 248 0.143
protein deneddylation GO:0000338 8 0.140
spindle organization GO:0007051 253 0.137
mrna processing GO:0006397 104 0.135
eye development GO:0001654 323 0.134
regulation of organelle organization GO:0033043 196 0.125
regulation of protein metabolic process GO:0051246 256 0.123
cellular macromolecule localization GO:0070727 220 0.116
gonad development GO:0008406 50 0.109
dna damage checkpoint GO:0000077 78 0.106
negative regulation of cell cycle GO:0045786 116 0.103
organonitrogen compound metabolic process GO:1901564 318 0.099
reproductive system development GO:0061458 74 0.094
single organism nuclear import GO:1902593 51 0.092
negative regulation of gene expression GO:0010629 387 0.085
g2 dna damage checkpoint GO:0031572 69 0.084
apoptotic process GO:0006915 159 0.084
regulation of meiosis GO:0040020 3 0.083
centrosome cycle GO:0007098 137 0.082
protein localization GO:0008104 284 0.081
nuclear transport GO:0051169 72 0.080
response to abiotic stimulus GO:0009628 341 0.079
cell motility GO:0048870 251 0.077
positive regulation of rna biosynthetic process GO:1902680 266 0.076
mrna splicing via spliceosome GO:0000398 73 0.072
negative regulation of cellular metabolic process GO:0031324 382 0.070
regulation of cellular localization GO:0060341 136 0.068
protein localization to nucleus GO:0034504 55 0.067
cellular catabolic process GO:0044248 372 0.064
protein complex biogenesis GO:0070271 201 0.063
dna integrity checkpoint GO:0031570 81 0.062
mitotic g2 dna damage checkpoint GO:0007095 69 0.062
endocytosis GO:0006897 310 0.061
organelle fission GO:0048285 340 0.061
negative regulation of rna metabolic process GO:0051253 251 0.061
centrosome organization GO:0051297 163 0.060
intracellular transport GO:0046907 228 0.060
positive regulation of macromolecule metabolic process GO:0010604 405 0.058
intracellular protein transport GO:0006886 104 0.055
protein import into nucleus GO:0006606 51 0.054
small molecule metabolic process GO:0044281 305 0.053
rna processing GO:0006396 147 0.053
rna splicing GO:0008380 83 0.051
programmed cell death GO:0012501 257 0.050
regulation of programmed cell death GO:0043067 152 0.049
regulation of localization GO:0032879 275 0.048
ribonucleoside monophosphate metabolic process GO:0009161 51 0.046
heterocycle catabolic process GO:0046700 166 0.046
response to temperature stimulus GO:0009266 106 0.044
regulation of cell division GO:0051302 72 0.044
protein targeting to nucleus GO:0044744 51 0.043
single organism cellular localization GO:1902580 180 0.043
reproductive structure development GO:0048608 74 0.043
sex differentiation GO:0007548 81 0.043
cell migration GO:0016477 238 0.042
glycosyl compound metabolic process GO:1901657 127 0.042
growth GO:0040007 359 0.039
meiotic nuclear division GO:0007126 151 0.039
glycosyl compound catabolic process GO:1901658 112 0.038
catabolic process GO:0009056 409 0.038
carbohydrate derivative metabolic process GO:1901135 217 0.037
regulation of cell death GO:0010941 173 0.037
cellular protein localization GO:0034613 160 0.036
genitalia development GO:0048806 26 0.035
negative regulation of biosynthetic process GO:0009890 277 0.035
negative regulation of multicellular organismal process GO:0051241 142 0.034
regulation of apoptotic process GO:0042981 130 0.034
cellular nitrogen compound catabolic process GO:0044270 165 0.034
regulation of proteolysis GO:0030162 87 0.033
nuclear import GO:0051170 51 0.033
purine nucleotide metabolic process GO:0006163 146 0.032
nucleobase containing small molecule metabolic process GO:0055086 174 0.032
camera type eye development GO:0043010 4 0.032
mitotic nuclear division GO:0007067 213 0.032
cellular macromolecular complex assembly GO:0034622 153 0.031
macromolecule catabolic process GO:0009057 161 0.031
spermatogenesis GO:0007283 200 0.031
regulation of intracellular transport GO:0032386 64 0.031
ribonucleoside catabolic process GO:0042454 112 0.031
ribonucleotide metabolic process GO:0009259 145 0.030
organic substance catabolic process GO:1901575 308 0.030
response to radiation GO:0009314 155 0.030
cullin deneddylation GO:0010388 3 0.030
single organism catabolic process GO:0044712 228 0.030
positive regulation of rna metabolic process GO:0051254 271 0.029
organonitrogen compound catabolic process GO:1901565 128 0.028
establishment of protein localization to organelle GO:0072594 62 0.028
development of primary sexual characteristics GO:0045137 50 0.028
regulation of developmental growth GO:0048638 174 0.027
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.027
aging GO:0007568 143 0.027
multicellular organismal aging GO:0010259 140 0.027
regulation of cytoplasmic transport GO:1903649 47 0.026
retina development in camera type eye GO:0060041 4 0.025
peptidyl amino acid modification GO:0018193 105 0.025
immune system process GO:0002376 347 0.024
phagocytosis GO:0006909 215 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
protein targeting GO:0006605 64 0.024
intermediate filament based process GO:0045103 1 0.024
response to bacterium GO:0009617 198 0.023
establishment of protein localization GO:0045184 163 0.023
ribonucleotide catabolic process GO:0009261 109 0.023
nucleoside metabolic process GO:0009116 127 0.023
ribose phosphate metabolic process GO:0019693 145 0.023
meiotic cell cycle GO:0051321 171 0.023
establishment of localization in cell GO:0051649 402 0.022
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.022
regulation of growth GO:0040008 233 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.022
atp metabolic process GO:0046034 49 0.022
regulation of catabolic process GO:0009894 170 0.021
ovulation cycle GO:0042698 1 0.021
posttranscriptional gene silencing by rna GO:0035194 45 0.021
regulation of intracellular protein transport GO:0033157 46 0.021
regulation of rna splicing GO:0043484 69 0.021
aromatic compound catabolic process GO:0019439 166 0.020
regulation of protein transport GO:0051223 57 0.020
cytoplasmic transport GO:0016482 130 0.020
cell death GO:0008219 279 0.020
embryonic morphogenesis GO:0048598 206 0.019
proteolysis GO:0006508 192 0.019
nitrogen compound transport GO:0071705 85 0.019
negative regulation of cellular protein metabolic process GO:0032269 85 0.019
intracellular receptor signaling pathway GO:0030522 19 0.019
ribonucleoside metabolic process GO:0009119 127 0.019
purine nucleoside monophosphate metabolic process GO:0009126 50 0.019
death GO:0016265 284 0.019
response to biotic stimulus GO:0009607 294 0.018
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.018
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.018
positive regulation of nucleic acid templated transcription GO:1903508 266 0.018
regulation of mrna processing GO:0050684 71 0.017
response to other organism GO:0051707 293 0.017
purine nucleoside triphosphate catabolic process GO:0009146 108 0.017
nucleotide metabolic process GO:0009117 161 0.017
positive regulation of developmental growth GO:0048639 62 0.017
male gamete generation GO:0048232 201 0.017
regulation of nucleocytoplasmic transport GO:0046822 35 0.017
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.016
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.016
larval development GO:0002164 104 0.016
regulation of nuclear division GO:0051783 58 0.016
centrosome duplication GO:0051298 121 0.016
cellular response to nutrient GO:0031670 1 0.016
regulation of molecular function GO:0065009 217 0.016
negative regulation of signaling GO:0023057 219 0.015
negative regulation of gene expression epigenetic GO:0045814 77 0.015
regulation of ruffle assembly GO:1900027 1 0.015
negative regulation of nucleic acid templated transcription GO:1903507 240 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.015
reproductive behavior GO:0019098 122 0.015
regulation of transport GO:0051049 181 0.015
regulation of response to external stimulus GO:0032101 115 0.015
gland development GO:0048732 191 0.015
organic substance transport GO:0071702 257 0.014
protein modification by small protein conjugation or removal GO:0070647 106 0.014
nucleocytoplasmic transport GO:0006913 72 0.014
negative regulation of developmental process GO:0051093 201 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
border follicle cell delamination GO:0030709 3 0.014
response to organic substance GO:0010033 284 0.013
regulation of meiotic cell cycle GO:0051445 9 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
positive regulation of signaling GO:0023056 243 0.013
nucleoside triphosphate catabolic process GO:0009143 108 0.013
microtubule organizing center organization GO:0031023 168 0.013
nucleotide catabolic process GO:0009166 109 0.013
purine nucleoside triphosphate metabolic process GO:0009144 119 0.013
negative regulation of protein metabolic process GO:0051248 85 0.012
central nervous system development GO:0007417 201 0.012
posttranscriptional regulation of gene expression GO:0010608 145 0.012
regulation of hydrolase activity GO:0051336 97 0.012
localization of cell GO:0051674 257 0.012
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.012
regulation of mrna splicing via spliceosome GO:0048024 64 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
carbohydrate derivative catabolic process GO:1901136 118 0.012
immune system development GO:0002520 57 0.012
developmental growth GO:0048589 280 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
purine containing compound catabolic process GO:0072523 112 0.012
negative regulation of cell death GO:0060548 81 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.012
regulation of protein import into nucleus GO:0042306 28 0.011
nucleus organization GO:0006997 45 0.011
phospholipid transport GO:0015914 2 0.011
nucleoside catabolic process GO:0009164 112 0.011
protein catabolic process GO:0030163 101 0.011
rna splicing via transesterification reactions GO:0000375 73 0.011
receptor mediated endocytosis GO:0006898 21 0.011
regulation of mrna metabolic process GO:1903311 72 0.011
organonitrogen compound biosynthetic process GO:1901566 117 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
rna interference GO:0016246 27 0.011
regulation of protein localization to nucleus GO:1900180 29 0.011
positive regulation of neuron projection regeneration GO:0070572 3 0.011
negative regulation of signal transduction GO:0009968 206 0.011
single organism intracellular transport GO:1902582 207 0.011
histone modification GO:0016570 106 0.010
nucleoside monophosphate metabolic process GO:0009123 52 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
peptidyl serine phosphorylation GO:0018105 7 0.010
formation of a compartment boundary GO:0060288 4 0.010
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.010
protein maturation GO:0051604 71 0.010

Nup50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.018