Drosophila melanogaster

78 known processes

ran (Dmel_CG1404)

CG1404 gene product from transcript CG1404-RB

(Aliases: Dmel\CG1404,ran10A,Ran,l(1)G0075,CG1404,AAF30287,dran)

ran biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
regulation of cellular component biogenesis GO:0044087 201 0.697
spindle organization GO:0007051 253 0.581
meiotic cell cycle process GO:1903046 132 0.498
chromatin organization GO:0006325 207 0.403
negative regulation of cellular component organization GO:0051129 108 0.320
dna metabolic process GO:0006259 227 0.297
embryo development ending in birth or egg hatching GO:0009792 152 0.297
eye development GO:0001654 323 0.295
protein complex biogenesis GO:0070271 201 0.284
photoreceptor cell differentiation GO:0046530 170 0.268
establishment of organelle localization GO:0051656 122 0.264
organelle fission GO:0048285 340 0.256
sex differentiation GO:0007548 81 0.248
macromolecular complex assembly GO:0065003 256 0.238
chromosome organization GO:0051276 360 0.234
mitotic spindle organization GO:0007052 220 0.214
positive regulation of peptidase activity GO:0010952 29 0.209
positive regulation of cellular component biogenesis GO:0044089 80 0.200
growth GO:0040007 359 0.194
mrna splicing via spliceosome GO:0000398 73 0.185
nuclear division GO:0000280 332 0.183
compound eye morphogenesis GO:0001745 249 0.167
cellular protein modification process GO:0006464 438 0.164
intracellular signal transduction GO:0035556 300 0.162
small molecule metabolic process GO:0044281 305 0.160
Yeast
meiotic spindle organization GO:0000212 36 0.153
regulation of mrna processing GO:0050684 71 0.152
dna conformation change GO:0071103 105 0.151
larval development GO:0002164 104 0.146
mitotic nuclear division GO:0007067 213 0.139
rna splicing GO:0008380 83 0.139
positive regulation of rna biosynthetic process GO:1902680 266 0.138
regulation of dna templated transcription elongation GO:0032784 17 0.137
oocyte axis specification GO:0007309 108 0.131
endocytosis GO:0006897 310 0.131
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.123
positive regulation of macromolecule metabolic process GO:0010604 405 0.123
establishment or maintenance of cell polarity GO:0007163 167 0.122
regulation of cell cycle phase transition GO:1901987 130 0.122
axis specification GO:0009798 167 0.119
negative regulation of response to stimulus GO:0048585 258 0.116
regulation of cell cycle process GO:0010564 181 0.113
negative regulation of gene expression GO:0010629 387 0.111
Yeast
dorsal ventral axis specification GO:0009950 66 0.111
positive regulation of cellular component organization GO:0051130 156 0.110
regulation of protein metabolic process GO:0051246 256 0.109
post embryonic appendage morphogenesis GO:0035120 385 0.108
phagocytosis GO:0006909 215 0.107
negative regulation of developmental process GO:0051093 201 0.106
mitotic cell cycle phase transition GO:0044772 138 0.105
positive regulation of catalytic activity GO:0043085 118 0.103
protein modification process GO:0036211 438 0.098
developmental maturation GO:0021700 172 0.098
positive regulation of nucleic acid templated transcription GO:1903508 266 0.096
regulation of cell cycle GO:0051726 291 0.094
regulation of cellular protein metabolic process GO:0032268 243 0.093
covalent chromatin modification GO:0016569 106 0.092
eye morphogenesis GO:0048592 260 0.089
sensory organ morphogenesis GO:0090596 260 0.088
regulation of microtubule cytoskeleton organization GO:0070507 41 0.087
positive regulation of hydrolase activity GO:0051345 78 0.085
mapk cascade GO:0000165 107 0.085
chromatin modification GO:0016568 147 0.085
protein complex assembly GO:0006461 200 0.084
female meiotic division GO:0007143 70 0.083
negative regulation of cell cycle GO:0045786 116 0.081
positive regulation of molecular function GO:0044093 136 0.081
oxoacid metabolic process GO:0043436 103 0.080
compound eye photoreceptor cell differentiation GO:0001751 140 0.078
regulation of developmental growth GO:0048638 174 0.077
regulation of apoptotic process GO:0042981 130 0.074
programmed cell death GO:0012501 257 0.073
response to organic substance GO:0010033 284 0.072
positive regulation of proteolysis GO:0045862 52 0.070
regulation of mrna metabolic process GO:1903311 72 0.068
regulation of cellular catabolic process GO:0031329 157 0.067
regulation of mitotic cell cycle GO:0007346 190 0.065
compound eye development GO:0048749 307 0.065
organic substance catabolic process GO:1901575 308 0.065
Yeast
phosphorylation GO:0016310 294 0.063
positive regulation of developmental process GO:0051094 143 0.063
response to heat GO:0009408 63 0.063
organic acid metabolic process GO:0006082 103 0.060
negative regulation of organelle organization GO:0010639 56 0.059
cell cycle phase transition GO:0044770 140 0.055
positive regulation of cell communication GO:0010647 250 0.055
appendage development GO:0048736 401 0.055
regulation of growth GO:0040008 233 0.054
regulation of organelle organization GO:0033043 196 0.054
regulation of locomotion GO:0040012 42 0.053
positive regulation of protein metabolic process GO:0051247 128 0.052
regulation of mitotic cell cycle phase transition GO:1901990 130 0.052
vesicle mediated transport GO:0016192 381 0.052
regulation of proteasomal protein catabolic process GO:0061136 39 0.051
regulation of cytoskeleton organization GO:0051493 89 0.051
regulation of cell development GO:0060284 215 0.049
cellular protein complex assembly GO:0043623 71 0.048
cellular macromolecular complex assembly GO:0034622 153 0.047
microtubule organizing center organization GO:0031023 168 0.046
homeostatic process GO:0042592 199 0.044
ovarian follicle cell development GO:0030707 248 0.044
death GO:0016265 284 0.044
gene silencing by rna GO:0031047 57 0.043
regulation of localization GO:0032879 275 0.042
spermatogenesis GO:0007283 200 0.042
regulation of programmed cell death GO:0043067 152 0.042
regulation of cell death GO:0010941 173 0.042
germ line cyst formation GO:0048134 44 0.042
regulation of mrna splicing via spliceosome GO:0048024 64 0.041
protein polymerization GO:0051258 42 0.040
organonitrogen compound biosynthetic process GO:1901566 117 0.040
small gtpase mediated signal transduction GO:0007264 88 0.040
chromatin assembly or disassembly GO:0006333 52 0.039
dorsal ventral pattern formation GO:0009953 133 0.038
regulation of rna splicing GO:0043484 69 0.038
cellular homeostasis GO:0019725 80 0.038
negative regulation of multicellular organismal process GO:0051241 142 0.037
transcription from rna polymerase ii promoter GO:0006366 368 0.037
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.036
rna splicing via transesterification reactions GO:0000375 73 0.036
pronuclear migration GO:0035046 4 0.035
regulation of neurogenesis GO:0050767 158 0.035
positive regulation of biosynthetic process GO:0009891 316 0.035
chromatin assembly GO:0031497 48 0.035
developmental growth GO:0048589 280 0.034
epithelial cell development GO:0002064 274 0.034
regulation of nervous system development GO:0051960 248 0.034
positive regulation of intracellular signal transduction GO:1902533 116 0.034
reproductive system development GO:0061458 74 0.034
positive regulation of programmed cell death GO:0043068 62 0.033
negative regulation of cell differentiation GO:0045596 143 0.033
regulation of cell proliferation GO:0042127 163 0.033
organonitrogen compound metabolic process GO:1901564 318 0.032
Yeast
regulation of response to stress GO:0080134 200 0.032
protein localization GO:0008104 284 0.032
regulation of multicellular organismal development GO:2000026 414 0.031
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.031
imaginal disc derived appendage morphogenesis GO:0035114 395 0.030
negative regulation of cell communication GO:0010648 223 0.030
eye photoreceptor cell differentiation GO:0001754 145 0.030
positive regulation of endopeptidase activity GO:0010950 26 0.030
positive regulation of cellular protein metabolic process GO:0032270 118 0.030
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.030
developmental programmed cell death GO:0010623 138 0.028
mrna metabolic process GO:0016071 124 0.028
axonogenesis GO:0007409 290 0.027
neuron projection guidance GO:0097485 241 0.027
cellular macromolecule localization GO:0070727 220 0.027
erbb signaling pathway GO:0038127 58 0.027
gene silencing GO:0016458 138 0.027
Yeast
cellular response to dna damage stimulus GO:0006974 223 0.026
positive regulation of signaling GO:0023056 243 0.026
development of primary sexual characteristics GO:0045137 50 0.026
telencephalon development GO:0021537 2 0.026
ribonucleoprotein complex assembly GO:0022618 23 0.025
negative regulation of catabolic process GO:0009895 36 0.025
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.025
epithelial cell differentiation GO:0030855 322 0.025
ribonucleoside metabolic process GO:0009119 127 0.025
Yeast
anatomical structure homeostasis GO:0060249 97 0.025
response to dsrna GO:0043331 15 0.025
meiotic cell cycle GO:0051321 171 0.024
single organism biosynthetic process GO:0044711 206 0.024
organophosphate metabolic process GO:0019637 195 0.024
Yeast
protein import GO:0017038 55 0.024
rna processing GO:0006396 147 0.023
Yeast
cellular macromolecule catabolic process GO:0044265 136 0.023
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
cell cycle g1 s phase transition GO:0044843 31 0.023
negative regulation of signal transduction GO:0009968 206 0.023
protein dna complex assembly GO:0065004 63 0.022
regulation of cellular response to stress GO:0080135 89 0.022
macromolecule catabolic process GO:0009057 161 0.022
maintenance of location GO:0051235 73 0.022
positive regulation of protein complex assembly GO:0031334 22 0.022
learning GO:0007612 75 0.022
negative regulation of proteasomal protein catabolic process GO:1901799 16 0.022
regulation of molecular function GO:0065009 217 0.022
axon development GO:0061564 297 0.021
photoreceptor cell development GO:0042461 96 0.021
negative regulation of neurotransmitter secretion GO:0046929 2 0.021
determination of adult lifespan GO:0008340 137 0.021
regulation of cell cycle g1 s phase transition GO:1902806 23 0.021
oocyte microtubule cytoskeleton polarization GO:0008103 22 0.020
regulation of catalytic activity GO:0050790 185 0.020
enzyme linked receptor protein signaling pathway GO:0007167 179 0.020
ncrna metabolic process GO:0034660 43 0.020
Yeast
positive regulation of apoptotic process GO:0043065 47 0.020
regulation of catabolic process GO:0009894 170 0.020
histone methylation GO:0016571 40 0.020
single organism behavior GO:0044708 391 0.020
sister chromatid segregation GO:0000819 92 0.019
proteolysis GO:0006508 192 0.019
mitotic sister chromatid segregation GO:0000070 87 0.019
spindle assembly involved in meiosis GO:0090306 20 0.019
positive regulation of multi organism process GO:0043902 40 0.019
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.019
response to organic cyclic compound GO:0014070 89 0.019
positive regulation of gene expression GO:0010628 290 0.019
spindle assembly involved in mitosis GO:0090307 50 0.018
nucleus organization GO:0006997 45 0.018
Yeast
positive regulation of photoreceptor cell differentiation GO:0046534 12 0.018
nucleoside triphosphate catabolic process GO:0009143 108 0.018
Yeast
imaginal disc derived wing morphogenesis GO:0007476 337 0.018
reproductive structure development GO:0048608 74 0.018
adult behavior GO:0030534 137 0.017
centrosome cycle GO:0007098 137 0.017
proteasomal protein catabolic process GO:0010498 59 0.017
cell cell signaling involved in cell fate commitment GO:0045168 210 0.017
centrosome duplication GO:0051298 121 0.017
multicellular organism growth GO:0035264 46 0.017
histone modification GO:0016570 106 0.017
negative regulation of nervous system development GO:0051961 92 0.017
nucleocytoplasmic transport GO:0006913 72 0.017
negative regulation of rna biosynthetic process GO:1902679 240 0.017
Yeast
aromatic compound catabolic process GO:0019439 166 0.017
Yeast
positive regulation of organelle organization GO:0010638 65 0.017
organelle assembly GO:0070925 198 0.016
amine metabolic process GO:0009308 12 0.016
protein phosphorylation GO:0006468 169 0.016
imaginal disc derived appendage development GO:0048737 399 0.015
cellular response to organic substance GO:0071310 132 0.015
negative regulation of cell cycle process GO:0010948 109 0.015
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.015
regulation of phosphorus metabolic process GO:0051174 210 0.015
negative regulation of cell development GO:0010721 62 0.015
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0030722 6 0.015
dna double strand break processing GO:0000729 3 0.015
ras protein signal transduction GO:0007265 88 0.014
negative regulation of cellular protein metabolic process GO:0032269 85 0.014
regulation of chromatin assembly GO:0010847 9 0.014
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.014
regulation of protein complex assembly GO:0043254 42 0.014
negative regulation of phosphorus metabolic process GO:0010563 45 0.014
negative regulation of cytoskeleton organization GO:0051494 30 0.014
neurological system process GO:0050877 358 0.014
body morphogenesis GO:0010171 2 0.014
organelle localization GO:0051640 148 0.014
regulation of photoreceptor cell differentiation GO:0046532 34 0.014
regulation of cellular amino acid metabolic process GO:0006521 0 0.014
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.013
Yeast
cell cycle arrest GO:0007050 4 0.013
response to extracellular stimulus GO:0009991 116 0.013
multi organism behavior GO:0051705 175 0.013
neuron apoptotic process GO:0051402 17 0.013
negative regulation of intrinsic apoptotic signaling pathway GO:2001243 1 0.013
ribonucleoside triphosphate metabolic process GO:0009199 119 0.013
Yeast
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.013
exocrine system development GO:0035272 162 0.013
embryonic morphogenesis GO:0048598 206 0.013
oocyte development GO:0048599 124 0.013
single organism intracellular transport GO:1902582 207 0.013
posttranscriptional regulation of gene expression GO:0010608 145 0.013
response to abiotic stimulus GO:0009628 341 0.013
regulation of hydrolase activity GO:0051336 97 0.013
regulation of organ growth GO:0046620 42 0.012
apoptotic process GO:0006915 159 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
regulation of nuclear division GO:0051783 58 0.012
regulation of proteolysis GO:0030162 87 0.012
regulation of transport GO:0051049 181 0.012
learning or memory GO:0007611 141 0.012
negative regulation of signaling GO:0023057 219 0.012
cell proliferation GO:0008283 299 0.012
brain development GO:0007420 120 0.012
cognition GO:0050890 141 0.012
detection of light stimulus involved in visual perception GO:0050908 6 0.012
mitotic spindle elongation GO:0000022 81 0.012
gland development GO:0048732 191 0.012
regulation of epithelial cell proliferation GO:0050678 4 0.012
meiotic nuclear division GO:0007126 151 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.011
stem cell differentiation GO:0048863 117 0.011
g protein coupled receptor signaling pathway GO:0007186 136 0.011
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
positive regulation of growth GO:0045927 75 0.011
rna localization GO:0006403 115 0.011
head development GO:0060322 135 0.011
regulation of response to external stimulus GO:0032101 115 0.011
regulation of protein polymerization GO:0032271 28 0.011
regulation of hemocyte proliferation GO:0035206 37 0.011
positive regulation of signal transduction GO:0009967 223 0.011
response to hormone GO:0009725 45 0.011
spindle assembly GO:0051225 80 0.011
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.011
negative regulation of response to nutrient levels GO:0032108 6 0.011
response to alcohol GO:0097305 95 0.010
positive regulation of response to stimulus GO:0048584 323 0.010
cell maturation GO:0048469 144 0.010
positive regulation of rna metabolic process GO:0051254 271 0.010
multicellular organismal reproductive behavior GO:0033057 110 0.010
regulation of endocytosis GO:0030100 37 0.010
g1 s transition of mitotic cell cycle GO:0000082 31 0.010
actin filament based process GO:0030029 220 0.010
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.010
nuclear body organization GO:0030575 6 0.010
protein maturation GO:0051604 71 0.010
negative regulation of cellular metabolic process GO:0031324 382 0.010
Yeast
lipid metabolic process GO:0006629 121 0.010
response to temperature stimulus GO:0009266 106 0.010

ran disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.019
organ system cancer DOID:0050686 0 0.014
cancer DOID:162 0 0.014
disease of cellular proliferation DOID:14566 0 0.014
neurodegenerative disease DOID:1289 0 0.011
motor neuron disease DOID:231 0 0.011
central nervous system disease DOID:331 0 0.011
amyotrophic lateral sclerosis DOID:332 0 0.011
nervous system disease DOID:863 0 0.011