Drosophila melanogaster

0 known processes

mthl10 (Dmel_CG17061)

methuselah-like 10

(Aliases: mth2,anon-WO0170980.166,anon-WO0170980.167,CG17061,Dmel\CG17061)

mthl10 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
appendage morphogenesis GO:0035107 397 0.046
Fly
small molecule metabolic process GO:0044281 305 0.045
imaginal disc derived appendage morphogenesis GO:0035114 395 0.045
Fly
response to abiotic stimulus GO:0009628 341 0.044
Fly
organonitrogen compound metabolic process GO:1901564 318 0.043
lateral inhibition GO:0046331 206 0.043
cellular catabolic process GO:0044248 372 0.042
post embryonic appendage morphogenesis GO:0035120 385 0.041
Fly
appendage development GO:0048736 401 0.040
Fly
cell cell signaling involved in cell fate commitment GO:0045168 210 0.039
catabolic process GO:0009056 409 0.036
imaginal disc derived appendage development GO:0048737 399 0.035
Fly
response to light stimulus GO:0009416 124 0.035
regionalization GO:0003002 416 0.033
imaginal disc derived wing morphogenesis GO:0007476 337 0.033
Fly
wing disc morphogenesis GO:0007472 344 0.032
Fly
intracellular signal transduction GO:0035556 300 0.032
single organism behavior GO:0044708 391 0.031
protein modification process GO:0036211 438 0.030
body morphogenesis GO:0010171 2 0.028
phosphorylation GO:0016310 294 0.028
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.027
cellular protein modification process GO:0006464 438 0.026
negative regulation of cellular metabolic process GO:0031324 382 0.026
vesicle mediated transport GO:0016192 381 0.025
Fly
positive regulation of response to stimulus GO:0048584 323 0.025
regulation of catabolic process GO:0009894 170 0.024
organic substance transport GO:0071702 257 0.024
pigment metabolic process GO:0042440 84 0.024
positive regulation of cell communication GO:0010647 250 0.024
response to radiation GO:0009314 155 0.024
phagocytosis GO:0006909 215 0.024
cellular response to chemical stimulus GO:0070887 199 0.024
response to external biotic stimulus GO:0043207 293 0.024
endocytosis GO:0006897 310 0.023
response to biotic stimulus GO:0009607 294 0.023
negative regulation of biosynthetic process GO:0009890 277 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
response to organic substance GO:0010033 284 0.022
Fly
oxoacid metabolic process GO:0043436 103 0.021
response to lipopolysaccharide GO:0032496 4 0.021
regulation of localization GO:0032879 275 0.021
negative regulation of rna metabolic process GO:0051253 251 0.021
organic substance catabolic process GO:1901575 308 0.021
positive regulation of signal transduction GO:0009967 223 0.021
organelle fission GO:0048285 340 0.021
regulation of cell cycle GO:0051726 291 0.021
respiratory system development GO:0060541 213 0.021
single organism catabolic process GO:0044712 228 0.021
epithelial cell development GO:0002064 274 0.021
nuclear division GO:0000280 332 0.021
growth GO:0040007 359 0.021
positive regulation of signaling GO:0023056 243 0.020
response to organophosphorus GO:0046683 2 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
negative regulation of cellular biosynthetic process GO:0031327 277 0.020
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.020
multi organism behavior GO:0051705 175 0.020
regulation of cellular component biogenesis GO:0044087 201 0.020
negative regulation of response to stimulus GO:0048585 258 0.020
salivary gland development GO:0007431 162 0.020
regulation of mitotic cell cycle GO:0007346 190 0.020
single organism biosynthetic process GO:0044711 206 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
cell death GO:0008219 279 0.020
organic acid metabolic process GO:0006082 103 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
defense response GO:0006952 300 0.019
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.019
regulation of multicellular organismal development GO:2000026 414 0.019
cell proliferation GO:0008283 299 0.019
negative regulation of cell communication GO:0010648 223 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
response to bacterium GO:0009617 198 0.019
forebrain development GO:0030900 2 0.019
tissue morphogenesis GO:0048729 297 0.019
Fly
regulation of phosphorus metabolic process GO:0051174 210 0.019
compound eye development GO:0048749 307 0.019
response to oxygen containing compound GO:1901700 200 0.018
Fly
positive regulation of gene expression GO:0010628 290 0.018
transcription from rna polymerase ii promoter GO:0006366 368 0.018
actin filament based process GO:0030029 220 0.018
Fly
developmental maturation GO:0021700 172 0.018
protein localization GO:0008104 284 0.018
response to other organism GO:0051707 293 0.018
regulation of cellular catabolic process GO:0031329 157 0.018
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.018
adult behavior GO:0030534 137 0.018
gland morphogenesis GO:0022612 145 0.018
negative regulation of gene expression GO:0010629 387 0.018
defense response to bacterium GO:0042742 178 0.018
cell motility GO:0048870 251 0.018
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.018
negative regulation of signaling GO:0023057 219 0.017
actin cytoskeleton organization GO:0030036 206 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
epithelial cell differentiation GO:0030855 322 0.017
regulation of cell differentiation GO:0045595 302 0.017
defense response to other organism GO:0098542 225 0.017
tube development GO:0035295 244 0.017
Fly
macromolecule catabolic process GO:0009057 161 0.017
intracellular transport GO:0046907 228 0.017
morphogenesis of an epithelium GO:0002009 276 0.017
organophosphate metabolic process GO:0019637 195 0.017
open tracheal system development GO:0007424 204 0.017
neurological system process GO:0050877 358 0.017
biological adhesion GO:0022610 138 0.017
regulation of growth GO:0040008 233 0.016
rna localization GO:0006403 115 0.016
connective tissue development GO:0061448 3 0.016
death GO:0016265 284 0.016
regulation of intracellular signal transduction GO:1902531 236 0.016
negative regulation of rna biosynthetic process GO:1902679 240 0.016
chaeta development GO:0022416 97 0.016
regulation of cellular amine metabolic process GO:0033238 3 0.016
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
purine containing compound metabolic process GO:0072521 155 0.016
salivary gland morphogenesis GO:0007435 145 0.016
embryonic morphogenesis GO:0048598 206 0.016
Fly
organic cyclic compound catabolic process GO:1901361 168 0.016
developmental growth GO:0048589 280 0.016
kidney development GO:0001822 3 0.016
nucleobase containing small molecule metabolic process GO:0055086 174 0.016
negative regulation of signal transduction GO:0009968 206 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
spindle organization GO:0007051 253 0.016
mitotic nuclear division GO:0007067 213 0.016
immune system process GO:0002376 347 0.016
positive regulation of molecular function GO:0044093 136 0.015
g protein coupled receptor signaling pathway GO:0007186 136 0.015
Fly
programmed cell death GO:0012501 257 0.015
cellular macromolecule localization GO:0070727 220 0.015
l amino acid import GO:0043092 2 0.015
cell cycle phase transition GO:0044770 140 0.015
tissue death GO:0016271 102 0.015
regulation of cell cycle process GO:0010564 181 0.015
regulation of protein metabolic process GO:0051246 256 0.015
cellular macromolecule catabolic process GO:0044265 136 0.015
lipid metabolic process GO:0006629 121 0.015
exocrine system development GO:0035272 162 0.015
regulation of cellular ketone metabolic process GO:0010565 3 0.015
protein catabolic process GO:0030163 101 0.015
aromatic compound catabolic process GO:0019439 166 0.015
positive regulation of cellular catabolic process GO:0031331 95 0.015
regulation of molecular function GO:0065009 217 0.015
developmental programmed cell death GO:0010623 138 0.015
positive regulation of catabolic process GO:0009896 105 0.015
regulation of cell proliferation GO:0042127 163 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
positive regulation of macromolecule metabolic process GO:0010604 405 0.015
ras protein signal transduction GO:0007265 88 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
organonitrogen compound catabolic process GO:1901565 128 0.014
gland development GO:0048732 191 0.014
embryonic axis specification GO:0000578 107 0.014
nucleotide metabolic process GO:0009117 161 0.014
regulation of transport GO:0051049 181 0.014
cell migration GO:0016477 238 0.014
secondary metabolic process GO:0019748 75 0.014
regulation of cell development GO:0060284 215 0.014
posttranscriptional regulation of gene expression GO:0010608 145 0.014
regulation of cellular protein metabolic process GO:0032268 243 0.014
regulation of immune system process GO:0002682 176 0.014
endomembrane system organization GO:0010256 119 0.014
positive regulation of phosphorus metabolic process GO:0010562 139 0.014
spermatogenesis GO:0007283 200 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
single organism intracellular transport GO:1902582 207 0.014
modification dependent protein catabolic process GO:0019941 78 0.014
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.014
rna processing GO:0006396 147 0.014
ubiquitin dependent protein catabolic process GO:0006511 78 0.014
enzyme linked receptor protein signaling pathway GO:0007167 179 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
regulation of anatomical structure size GO:0090066 163 0.014
taxis GO:0042330 304 0.014
protein phosphorylation GO:0006468 169 0.014
organelle assembly GO:0070925 198 0.014
ribonucleotide metabolic process GO:0009259 145 0.014
regulation of organelle organization GO:0033043 196 0.014
cellular protein catabolic process GO:0044257 83 0.014
heterocycle catabolic process GO:0046700 166 0.014
histolysis GO:0007559 102 0.013
localization of cell GO:0051674 257 0.013
establishment of localization in cell GO:0051649 402 0.013
Fly
cell maturation GO:0048469 144 0.013
eye development GO:0001654 323 0.013
regulation of cell death GO:0010941 173 0.013
mrna metabolic process GO:0016071 124 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
autophagic cell death GO:0048102 83 0.013
purine ribonucleotide metabolic process GO:0009150 145 0.013
regulation of response to stress GO:0080134 200 0.013
segmentation GO:0035282 207 0.013
macromolecular complex assembly GO:0065003 256 0.013
cellular amine metabolic process GO:0044106 12 0.013
cellular response to organic substance GO:0071310 132 0.013
establishment of protein localization GO:0045184 163 0.013
ion transport GO:0006811 145 0.013
dna metabolic process GO:0006259 227 0.013
positive regulation of catalytic activity GO:0043085 118 0.013
positive regulation of cellular biosynthetic process GO:0031328 316 0.013
protein transport GO:0015031 155 0.013
positive regulation of developmental process GO:0051094 143 0.013
cell adhesion GO:0007155 136 0.013
dorsal ventral pattern formation GO:0009953 133 0.013
regulation of phosphorylation GO:0042325 147 0.013
organonitrogen compound biosynthetic process GO:1901566 117 0.013
nucleoside metabolic process GO:0009116 127 0.013
purine containing compound catabolic process GO:0072523 112 0.013
positive regulation of cell motility GO:2000147 3 0.013
compound eye morphogenesis GO:0001745 249 0.013
defense response to gram negative bacterium GO:0050829 94 0.013
regulation of rna splicing GO:0043484 69 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
mitotic spindle organization GO:0007052 220 0.013
pigmentation GO:0043473 75 0.013
digestive tract development GO:0048565 149 0.013
Fly
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
blastoderm segmentation GO:0007350 159 0.012
actin filament organization GO:0007015 126 0.012
cellular response to molecule of bacterial origin GO:0071219 3 0.012
chromatin organization GO:0006325 207 0.012
axis specification GO:0009798 167 0.012
positive regulation of cell migration GO:0030335 2 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
regulation of cellular localization GO:0060341 136 0.012
cellular response to lipopolysaccharide GO:0071222 3 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
proteolysis GO:0006508 192 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
notch signaling pathway GO:0007219 120 0.012
regulation of cell cycle phase transition GO:1901987 130 0.012
cell division GO:0051301 248 0.012
response to nutrient levels GO:0031667 114 0.012
Fly
detection of stimulus GO:0051606 156 0.012
tube morphogenesis GO:0035239 191 0.012
Fly
eye morphogenesis GO:0048592 260 0.012
nucleobase containing compound catabolic process GO:0034655 165 0.012
mrna processing GO:0006397 104 0.012
telencephalon development GO:0021537 2 0.012
central nervous system development GO:0007417 201 0.012
homeostatic process GO:0042592 199 0.012
embryonic pattern specification GO:0009880 174 0.012
gene silencing GO:0016458 138 0.012
salivary gland cell autophagic cell death GO:0035071 83 0.012
mating GO:0007618 120 0.012
steroid catabolic process GO:0006706 1 0.012
single organism cellular localization GO:1902580 180 0.012
ribonucleoside catabolic process GO:0042454 112 0.012
chromosome segregation GO:0007059 157 0.012
multicellular organismal aging GO:0010259 140 0.012
Fly
ribonucleoside metabolic process GO:0009119 127 0.012
camera type eye development GO:0043010 4 0.012
regulation of developmental growth GO:0048638 174 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
response to temperature stimulus GO:0009266 106 0.012
Fly
male gamete generation GO:0048232 201 0.012
regulation of nervous system development GO:0051960 248 0.012
protein complex assembly GO:0006461 200 0.012
salivary gland histolysis GO:0035070 88 0.012
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.012
nucleoside triphosphate catabolic process GO:0009143 108 0.012
modification dependent macromolecule catabolic process GO:0043632 79 0.012
regulation of programmed cell death GO:0043067 152 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
amine metabolic process GO:0009308 12 0.012
negative regulation of growth GO:0045926 84 0.012
nucleoside triphosphate metabolic process GO:0009141 120 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
negative regulation of developmental process GO:0051093 201 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
regulation of catalytic activity GO:0050790 185 0.011
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.011
immune response GO:0006955 246 0.011
protein complex biogenesis GO:0070271 201 0.011
carbohydrate derivative catabolic process GO:1901136 118 0.011
organophosphate catabolic process GO:0046434 112 0.011
nitrogen compound transport GO:0071705 85 0.011
xenobiotic catabolic process GO:0042178 1 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
tissue migration GO:0090130 155 0.011
Fly
leg disc development GO:0035218 92 0.011
sensory organ morphogenesis GO:0090596 260 0.011
imaginal disc pattern formation GO:0007447 91 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
aging GO:0007568 143 0.011
Fly
apoptotic process GO:0006915 159 0.011
negative regulation of cellular component organization GO:0051129 108 0.011
chemotaxis GO:0006935 249 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
developmental pigmentation GO:0048066 68 0.011
purine ribonucleoside catabolic process GO:0046130 112 0.011
purine ribonucleotide catabolic process GO:0009154 109 0.011
ribonucleoside triphosphate catabolic process GO:0009203 108 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
regulation of gene expression epigenetic GO:0040029 128 0.011
phosphate ion transport GO:0006817 4 0.011
regulation of mapk cascade GO:0043408 92 0.011
positive regulation of transcription dna templated GO:0045893 266 0.011
mapk cascade GO:0000165 107 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
microtubule organizing center organization GO:0031023 168 0.011
androgen metabolic process GO:0008209 1 0.011
cell cycle checkpoint GO:0000075 95 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
epithelial cell migration GO:0010631 148 0.010
membrane organization GO:0061024 112 0.010
cellular protein localization GO:0034613 160 0.010
negative regulation of protein metabolic process GO:0051248 85 0.010
cellular lipid metabolic process GO:0044255 83 0.010
ribonucleotide catabolic process GO:0009261 109 0.010
axon development GO:0061564 297 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
leg disc morphogenesis GO:0007478 80 0.010
digestive system development GO:0055123 149 0.010
Fly
purine nucleotide catabolic process GO:0006195 109 0.010
olfactory behavior GO:0042048 97 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
ethanolamine containing compound metabolic process GO:0042439 4 0.010
nucleoside catabolic process GO:0009164 112 0.010
chromatin modification GO:0016568 147 0.010
covalent chromatin modification GO:0016569 106 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
cell projection assembly GO:0030031 94 0.010
determination of adult lifespan GO:0008340 137 0.010
Fly
meiotic cell cycle GO:0051321 171 0.010
chromosome organization GO:0051276 360 0.010
response to extracellular stimulus GO:0009991 116 0.010
Fly
establishment or maintenance of cell polarity GO:0007163 167 0.010
regulation of small gtpase mediated signal transduction GO:0051056 93 0.010
cellular response to oxygen containing compound GO:1901701 79 0.010
response to endogenous stimulus GO:0009719 119 0.010
nucleotide catabolic process GO:0009166 109 0.010
anterior posterior axis specification embryo GO:0008595 103 0.010

mthl10 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.016
disease of metabolism DOID:0014667 0 0.013
inherited metabolic disorder DOID:655 0 0.013
cardiovascular system disease DOID:1287 0 0.011