Drosophila melanogaster

56 known processes

siz (Dmel_CG32434)

schizo

(Aliases: Dmel\CG32434,CG12981,Loner,loner,CG10577,CG32434,CG12980)

siz biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
aggressive behavior GO:0002118 63 0.849
myoblast fusion GO:0007520 43 0.803
syncytium formation by plasma membrane fusion GO:0000768 43 0.676
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.664
myotube differentiation GO:0014902 46 0.663
syncytium formation GO:0006949 43 0.530
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.513
striated muscle cell differentiation GO:0051146 90 0.474
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.349
eye development GO:0001654 323 0.343
respiratory system development GO:0060541 213 0.322
muscle cell differentiation GO:0042692 103 0.276
positive regulation of ras gtpase activity GO:0032320 36 0.249
axon development GO:0061564 297 0.234
cell migration GO:0016477 238 0.227
regulation of cell development GO:0060284 215 0.226
response to organic substance GO:0010033 284 0.224
epithelial cell differentiation GO:0030855 322 0.212
imaginal disc derived appendage development GO:0048737 399 0.210
small gtpase mediated signal transduction GO:0007264 88 0.195
compound eye morphogenesis GO:0001745 249 0.193
head development GO:0060322 135 0.179
axonogenesis GO:0007409 290 0.171
single organism catabolic process GO:0044712 228 0.166
response to gravity GO:0009629 26 0.159
regulation of cellular catabolic process GO:0031329 157 0.157
cell motility GO:0048870 251 0.153
ribose phosphate metabolic process GO:0019693 145 0.153
cellular protein modification process GO:0006464 438 0.149
regulation of catabolic process GO:0009894 170 0.149
ventral cord development GO:0007419 16 0.147
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.147
ras protein signal transduction GO:0007265 88 0.144
purine nucleotide metabolic process GO:0006163 146 0.143
single organism behavior GO:0044708 391 0.143
ribonucleoside triphosphate catabolic process GO:0009203 108 0.139
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.135
cellular catabolic process GO:0044248 372 0.133
protein modification process GO:0036211 438 0.130
open tracheal system development GO:0007424 204 0.128
multi organism behavior GO:0051705 175 0.126
gtp catabolic process GO:0006184 72 0.126
sensory organ morphogenesis GO:0090596 260 0.122
response to oxygen containing compound GO:1901700 200 0.120
positive regulation of gtpase activity GO:0043547 43 0.117
positive regulation of nucleoside metabolic process GO:0045979 47 0.116
positive regulation of gtp catabolic process GO:0033126 43 0.115
organonitrogen compound metabolic process GO:1901564 318 0.114
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.111
positive regulation of biosynthetic process GO:0009891 316 0.111
guanosine containing compound catabolic process GO:1901069 74 0.111
purine nucleotide catabolic process GO:0006195 109 0.111
localization of cell GO:0051674 257 0.110
skin development GO:0043588 65 0.107
positive regulation of cellular biosynthetic process GO:0031328 316 0.106
morphogenesis of an epithelium GO:0002009 276 0.104
positive regulation of catalytic activity GO:0043085 118 0.103
central nervous system development GO:0007417 201 0.100
positive regulation of nucleotide metabolic process GO:0045981 55 0.100
taxis GO:0042330 304 0.098
nucleoside phosphate metabolic process GO:0006753 162 0.095
activation of ras gtpase activity GO:0032856 6 0.094
regulation of molecular function GO:0065009 217 0.093
response to abiotic stimulus GO:0009628 341 0.093
regulation of intracellular signal transduction GO:1902531 236 0.092
regulation of nucleotide catabolic process GO:0030811 48 0.092
positive regulation of gene expression GO:0010628 290 0.091
substrate adhesion dependent cell spreading GO:0034446 2 0.089
apoptotic process GO:0006915 159 0.089
morphogenesis of embryonic epithelium GO:0016331 94 0.088
muscle structure development GO:0061061 224 0.088
regulation of ras gtpase activity GO:0032318 38 0.088
regulation of nucleoside metabolic process GO:0009118 50 0.087
positive regulation of nucleic acid templated transcription GO:1903508 266 0.086
positive regulation of phosphate metabolic process GO:0045937 139 0.085
ribonucleoside triphosphate metabolic process GO:0009199 119 0.085
heterocycle catabolic process GO:0046700 166 0.084
behavioral response to ethanol GO:0048149 49 0.082
gliogenesis GO:0042063 80 0.082
forebrain development GO:0030900 2 0.081
regulation of small gtpase mediated signal transduction GO:0051056 93 0.081
regulation of gtpase activity GO:0043087 44 0.081
intracellular signal transduction GO:0035556 300 0.081
axon guidance GO:0007411 233 0.080
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.077
positive regulation of response to stimulus GO:0048584 323 0.077
ribonucleotide metabolic process GO:0009259 145 0.077
glycosyl compound metabolic process GO:1901657 127 0.077
positive regulation of molecular function GO:0044093 136 0.075
epidermis development GO:0008544 65 0.075
positive regulation of phosphorus metabolic process GO:0010562 139 0.074
purine ribonucleotide metabolic process GO:0009150 145 0.074
positive regulation of macromolecule metabolic process GO:0010604 405 0.074
positive regulation of hydrolase activity GO:0051345 78 0.074
purine containing compound metabolic process GO:0072521 155 0.073
programmed cell death GO:0012501 257 0.073
ribonucleoside metabolic process GO:0009119 127 0.072
brain development GO:0007420 120 0.072
regulation of organelle organization GO:0033043 196 0.072
cellular response to dna damage stimulus GO:0006974 223 0.071
regulation of multicellular organismal development GO:2000026 414 0.070
leg disc development GO:0035218 92 0.070
nucleotide metabolic process GO:0009117 161 0.069
organophosphate metabolic process GO:0019637 195 0.069
purine ribonucleoside metabolic process GO:0046128 127 0.069
cell death GO:0008219 279 0.068
regulation of cell differentiation GO:0045595 302 0.068
negative regulation of response to stimulus GO:0048585 258 0.068
catabolic process GO:0009056 409 0.066
ribonucleoside catabolic process GO:0042454 112 0.066
purine ribonucleotide catabolic process GO:0009154 109 0.065
somatic muscle development GO:0007525 66 0.065
nucleoside phosphate catabolic process GO:1901292 110 0.064
regulation of purine nucleotide catabolic process GO:0033121 48 0.064
positive regulation of cellular catabolic process GO:0031331 95 0.063
gtp metabolic process GO:0046039 72 0.063
appendage development GO:0048736 401 0.063
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.062
positive regulation of catabolic process GO:0009896 105 0.062
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.062
inter male aggressive behavior GO:0002121 60 0.062
actin filament based process GO:0030029 220 0.062
purine nucleoside metabolic process GO:0042278 127 0.061
immune system process GO:0002376 347 0.060
biological adhesion GO:0022610 138 0.060
regulation of apoptotic process GO:0042981 130 0.060
regulation of nucleotide metabolic process GO:0006140 62 0.059
rho protein signal transduction GO:0007266 14 0.058
chemotaxis GO:0006935 249 0.058
regulation of cell death GO:0010941 173 0.058
nucleobase containing small molecule metabolic process GO:0055086 174 0.057
organic substance catabolic process GO:1901575 308 0.057
regulation of rho gtpase activity GO:0032319 20 0.055
positive regulation of transcription dna templated GO:0045893 266 0.055
purine nucleoside triphosphate metabolic process GO:0009144 119 0.055
organonitrogen compound catabolic process GO:1901565 128 0.054
regulation of programmed cell death GO:0043067 152 0.054
positive regulation of developmental process GO:0051094 143 0.054
negative regulation of multicellular organismal process GO:0051241 142 0.053
glial cell migration GO:0008347 31 0.053
regulation of gtp catabolic process GO:0033124 44 0.052
ovarian follicle cell development GO:0030707 248 0.052
negative regulation of cellular component organization GO:0051129 108 0.051
tissue morphogenesis GO:0048729 297 0.051
eye morphogenesis GO:0048592 260 0.050
establishment of tissue polarity GO:0007164 87 0.049
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.048
regulation of purine nucleotide metabolic process GO:1900542 62 0.048
regulation of phosphate metabolic process GO:0019220 210 0.048
regulation of neuron differentiation GO:0045664 103 0.048
purine nucleoside triphosphate catabolic process GO:0009146 108 0.048
ribonucleotide catabolic process GO:0009261 109 0.047
transcription from rna polymerase ii promoter GO:0006366 368 0.047
gland development GO:0048732 191 0.047
nucleoside triphosphate catabolic process GO:0009143 108 0.047
negative regulation of gene expression GO:0010629 387 0.046
glycosyl compound catabolic process GO:1901658 112 0.046
epidermal cell differentiation GO:0009913 51 0.046
death GO:0016265 284 0.046
negative regulation of cell communication GO:0010648 223 0.045
response to nitrogen compound GO:1901698 90 0.045
carbohydrate derivative catabolic process GO:1901136 118 0.045
positive regulation of signal transduction GO:0009967 223 0.045
vesicle mediated transport GO:0016192 381 0.044
purine containing compound catabolic process GO:0072523 112 0.044
positive regulation of programmed cell death GO:0043068 62 0.044
negative regulation of programmed cell death GO:0043069 72 0.044
epithelial cell development GO:0002064 274 0.044
cellular response to chemical stimulus GO:0070887 199 0.043
response to oxidative stress GO:0006979 86 0.043
regulation of catalytic activity GO:0050790 185 0.043
regulation of phosphorus metabolic process GO:0051174 210 0.043
associative learning GO:0008306 65 0.042
regulation of ras protein signal transduction GO:0046578 93 0.041
purine nucleoside catabolic process GO:0006152 112 0.041
small molecule metabolic process GO:0044281 305 0.041
regulation of neurogenesis GO:0050767 158 0.041
establishment or maintenance of cell polarity GO:0007163 167 0.040
regulation of response to stress GO:0080134 200 0.040
regulation of hydrolase activity GO:0051336 97 0.040
cell adhesion GO:0007155 136 0.040
regulation of localization GO:0032879 275 0.040
photoreceptor cell axon guidance GO:0072499 23 0.039
purine ribonucleoside catabolic process GO:0046130 112 0.039
cellular response to oxygen containing compound GO:1901701 79 0.039
locomotory behavior GO:0007626 176 0.038
post embryonic appendage morphogenesis GO:0035120 385 0.038
positive regulation of cell development GO:0010720 61 0.037
positive regulation of rna biosynthetic process GO:1902680 266 0.037
negative regulation of rna biosynthetic process GO:1902679 240 0.037
positive regulation of rna metabolic process GO:0051254 271 0.037
imaginal disc derived leg morphogenesis GO:0007480 80 0.037
organophosphate catabolic process GO:0046434 112 0.037
organic cyclic compound catabolic process GO:1901361 168 0.036
regulation of behavior GO:0050795 75 0.036
guanosine containing compound metabolic process GO:1901068 74 0.036
nucleoside triphosphate metabolic process GO:0009141 120 0.036
response to ethanol GO:0045471 59 0.036
columnar cuboidal epithelial cell development GO:0002066 249 0.036
positive regulation of multicellular organismal process GO:0051240 143 0.036
telencephalon development GO:0021537 2 0.035
phosphorylation GO:0016310 294 0.035
dorsal closure GO:0007391 79 0.035
response to alcohol GO:0097305 95 0.034
homeostatic process GO:0042592 199 0.034
protein localization GO:0008104 284 0.034
olfactory behavior GO:0042048 97 0.034
negative regulation of biosynthetic process GO:0009890 277 0.034
negative regulation of cellular metabolic process GO:0031324 382 0.034
oxoacid metabolic process GO:0043436 103 0.033
leg disc morphogenesis GO:0007478 80 0.033
aromatic compound catabolic process GO:0019439 166 0.033
regulation of cell morphogenesis GO:0022604 163 0.033
renal system development GO:0072001 72 0.033
phagocytosis GO:0006909 215 0.033
nucleoside metabolic process GO:0009116 127 0.031
cell cycle phase transition GO:0044770 140 0.031
nucleotide catabolic process GO:0009166 109 0.031
response to nutrient levels GO:0031667 114 0.030
protein modification by small protein conjugation or removal GO:0070647 106 0.030
posttranscriptional regulation of gene expression GO:0010608 145 0.030
proteolysis GO:0006508 192 0.030
axon midline choice point recognition GO:0016199 26 0.029
positive regulation of nucleotide catabolic process GO:0030813 46 0.029
neurological system process GO:0050877 358 0.029
single organism biosynthetic process GO:0044711 206 0.029
positive regulation of cell communication GO:0010647 250 0.028
drinking behavior GO:0042756 2 0.028
tube development GO:0035295 244 0.028
positive regulation of protein metabolic process GO:0051247 128 0.028
developmental growth GO:0048589 280 0.028
regionalization GO:0003002 416 0.027
regulation of nervous system development GO:0051960 248 0.027
response to temperature stimulus GO:0009266 106 0.027
regulation of cellular component size GO:0032535 98 0.027
compound eye development GO:0048749 307 0.026
carboxylic acid metabolic process GO:0019752 92 0.026
growth GO:0040007 359 0.026
neuron fate commitment GO:0048663 50 0.026
eggshell formation GO:0030703 105 0.026
nucleoside catabolic process GO:0009164 112 0.026
regulation of protein metabolic process GO:0051246 256 0.026
negative regulation of developmental process GO:0051093 201 0.025
embryo development ending in birth or egg hatching GO:0009792 152 0.025
imaginal disc derived appendage morphogenesis GO:0035114 395 0.025
regulation of immune system process GO:0002682 176 0.025
negative regulation of cellular biosynthetic process GO:0031327 277 0.025
neuron projection guidance GO:0097485 241 0.024
organic substance transport GO:0071702 257 0.024
immune response regulating signaling pathway GO:0002764 2 0.024
carbohydrate derivative metabolic process GO:1901135 217 0.024
learning GO:0007612 75 0.024
lipid metabolic process GO:0006629 121 0.024
wing disc morphogenesis GO:0007472 344 0.023
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.023
regulation of growth GO:0040008 233 0.023
neuron recognition GO:0008038 101 0.023
compound eye photoreceptor cell differentiation GO:0001751 140 0.023
positive regulation of cellular protein metabolic process GO:0032270 118 0.022
positive regulation of rho gtpase activity GO:0032321 19 0.022
endocytosis GO:0006897 310 0.021
regulation of cytoskeleton organization GO:0051493 89 0.021
cellular response to organic substance GO:0071310 132 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
anatomical structure homeostasis GO:0060249 97 0.020
chromosome organization GO:0051276 360 0.020
regulation of cell shape GO:0008360 113 0.020
negative regulation of signaling GO:0023057 219 0.020
organelle localization GO:0051640 148 0.020
establishment of planar polarity GO:0001736 87 0.020
protein phosphorylation GO:0006468 169 0.020
organic hydroxy compound metabolic process GO:1901615 83 0.020
spermatogenesis GO:0007283 200 0.019
gene silencing GO:0016458 138 0.019
regulation of cell cycle GO:0051726 291 0.019
modification dependent protein catabolic process GO:0019941 78 0.019
male gamete generation GO:0048232 201 0.019
cellular component assembly involved in morphogenesis GO:0010927 151 0.019
salivary gland morphogenesis GO:0007435 145 0.019
positive regulation of cell differentiation GO:0045597 64 0.019
negative regulation of cell death GO:0060548 81 0.019
response to organonitrogen compound GO:0010243 75 0.019
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.018
hindbrain development GO:0030902 2 0.018
dna metabolic process GO:0006259 227 0.018
cell proliferation GO:0008283 299 0.018
regulation of anatomical structure size GO:0090066 163 0.018
developmental programmed cell death GO:0010623 138 0.017
cell fate specification GO:0001708 71 0.017
notch signaling pathway GO:0007219 120 0.017
negative regulation of axon extension GO:0030517 3 0.017
negative regulation of signal transduction GO:0009968 206 0.017
response to lipopolysaccharide GO:0032496 4 0.017
actin cytoskeleton organization GO:0030036 206 0.017
negative regulation of nucleic acid templated transcription GO:1903507 240 0.017
regulation of proteolysis GO:0030162 87 0.017
morphogenesis of a polarized epithelium GO:0001738 93 0.017
positive regulation of intracellular signal transduction GO:1902533 116 0.017
adult behavior GO:0030534 137 0.017
negative regulation of cell differentiation GO:0045596 143 0.017
positive regulation of cell death GO:0010942 69 0.017
organic acid metabolic process GO:0006082 103 0.017
response to hypoxia GO:0001666 53 0.017
response to hydrogen peroxide GO:0042542 11 0.017
antimicrobial humoral response GO:0019730 99 0.016
macromolecular complex assembly GO:0065003 256 0.016
protein modification by small protein conjugation GO:0032446 79 0.016
stem cell differentiation GO:0048863 117 0.016
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.016
spiracle morphogenesis open tracheal system GO:0035277 22 0.016
lipid storage GO:0019915 38 0.016
actin filament organization GO:0007015 126 0.015
nuclear division GO:0000280 332 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
immune system development GO:0002520 57 0.015
transmembrane transport GO:0055085 139 0.015
hematopoietic or lymphoid organ development GO:0048534 57 0.015
segmentation GO:0035282 207 0.015
single organism cell adhesion GO:0098602 47 0.015
negative regulation of neuron differentiation GO:0045665 16 0.015
dorsal appendage formation GO:0046843 47 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
regulation of phosphorylation GO:0042325 147 0.015
organelle fission GO:0048285 340 0.015
embryonic morphogenesis GO:0048598 206 0.015
epithelial tube morphogenesis GO:0060562 88 0.014
compound eye photoreceptor development GO:0042051 78 0.014
regulation of cell projection organization GO:0031344 92 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
cellular response to nitrogen compound GO:1901699 51 0.014
lamellipodium assembly GO:0030032 21 0.014
mushroom body development GO:0016319 70 0.014
response to extracellular stimulus GO:0009991 116 0.014
positive regulation of lipid metabolic process GO:0045834 4 0.014
maintenance of location GO:0051235 73 0.013
embryonic pattern specification GO:0009880 174 0.013
synapse assembly GO:0007416 143 0.013
chaeta development GO:0022416 97 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
regulation of mitotic cell cycle GO:0007346 190 0.013
cellular nitrogen compound catabolic process GO:0044270 165 0.013
regulation of response to external stimulus GO:0032101 115 0.013
response to starvation GO:0042594 97 0.013
regulation of lipid metabolic process GO:0019216 15 0.012
negative regulation of neurogenesis GO:0050768 53 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
mitotic cell cycle phase transition GO:0044772 138 0.012
positive regulation of cell substrate adhesion GO:0010811 1 0.012
neuroblast proliferation GO:0007405 74 0.012
cell cell signaling involved in cell fate commitment GO:0045168 210 0.012
sensory perception of pain GO:0019233 4 0.012
chemosensory behavior GO:0007635 106 0.012
regulation of endocytosis GO:0030100 37 0.012
response to radiation GO:0009314 155 0.012
regulation of membrane potential GO:0042391 35 0.012
membrane organization GO:0061024 112 0.012
positive regulation of cell growth GO:0030307 19 0.012
regulation of cell cycle process GO:0010564 181 0.012
positive regulation of apoptotic process GO:0043065 47 0.011
determination of adult lifespan GO:0008340 137 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
embryonic development via the syncytial blastoderm GO:0001700 148 0.011
salivary gland development GO:0007431 162 0.011
response to inorganic substance GO:0010035 44 0.011
digestive system development GO:0055123 149 0.011
autophagy GO:0006914 108 0.011
appendage morphogenesis GO:0035107 397 0.011
regulation of rho protein signal transduction GO:0035023 20 0.011
photoreceptor cell fate commitment GO:0046552 41 0.011
kidney development GO:0001822 3 0.011
camera type eye development GO:0043010 4 0.010
cellular amine metabolic process GO:0044106 12 0.010
cellular macromolecular complex assembly GO:0034622 153 0.010
protein complex biogenesis GO:0070271 201 0.010
rac protein signal transduction GO:0016601 3 0.010
synaptic transmission GO:0007268 288 0.010
cellular amino acid metabolic process GO:0006520 61 0.010
morphogenesis of a branching structure GO:0001763 45 0.010
establishment of organelle localization GO:0051656 122 0.010
organelle assembly GO:0070925 198 0.010
negative regulation of growth GO:0045926 84 0.010
positive regulation of immune system process GO:0002684 68 0.010
aging GO:0007568 143 0.010
eggshell chorion assembly GO:0007306 66 0.010
nephron tubule development GO:0072080 3 0.010
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.010
chemical homeostasis GO:0048878 92 0.010
limb development GO:0060173 1 0.010

siz disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.060
urinary system disease DOID:18 0 0.021
nervous system disease DOID:863 0 0.011
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011