Drosophila melanogaster

45 known processes

nvd (Dmel_CG40050)

neverland

(Aliases: CG40050,Dmel\CG40050,nvd-Dm)

nvd biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
steroid biosynthetic process GO:0006694 16 0.103
organic hydroxy compound metabolic process GO:1901615 83 0.096
small molecule metabolic process GO:0044281 305 0.093
organic hydroxy compound biosynthetic process GO:1901617 21 0.088
cellular ketone metabolic process GO:0042180 24 0.076
small molecule biosynthetic process GO:0044283 37 0.069
hormone biosynthetic process GO:0042446 20 0.062
rhythmic behavior GO:0007622 76 0.054
imaginal disc derived appendage morphogenesis GO:0035114 395 0.048
appendage development GO:0048736 401 0.048
lipid metabolic process GO:0006629 121 0.047
death GO:0016265 284 0.045
protein hydroxylation GO:0018126 1 0.043
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.040
post embryonic appendage morphogenesis GO:0035120 385 0.040
molting cycle chitin based cuticle GO:0007591 56 0.040
cell death GO:0008219 279 0.039
alcohol metabolic process GO:0006066 25 0.039
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.039
vesicle mediated transport GO:0016192 381 0.039
eye development GO:0001654 323 0.038
endocytosis GO:0006897 310 0.037
single organism behavior GO:0044708 391 0.037
eye morphogenesis GO:0048592 260 0.037
cellular amino acid metabolic process GO:0006520 61 0.036
appendage morphogenesis GO:0035107 397 0.036
compound eye morphogenesis GO:0001745 249 0.036
peptidyl proline hydroxylation GO:0019511 1 0.035
positive regulation of response to stimulus GO:0048584 323 0.034
g2 dna damage checkpoint GO:0031572 69 0.034
cellular protein modification process GO:0006464 438 0.033
ecdysteroid biosynthetic process GO:0045456 15 0.033
body morphogenesis GO:0010171 2 0.033
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.033
imaginal disc derived appendage development GO:0048737 399 0.032
protein localization GO:0008104 284 0.032
regulation of cell cycle process GO:0010564 181 0.032
regulation of cellular amino acid metabolic process GO:0006521 0 0.031
chaeta development GO:0022416 97 0.031
sterol metabolic process GO:0016125 12 0.031
cellular response to dna damage stimulus GO:0006974 223 0.031
negative regulation of nucleic acid templated transcription GO:1903507 240 0.031
protein modification process GO:0036211 438 0.030
compound eye development GO:0048749 307 0.030
imaginal disc derived wing morphogenesis GO:0007476 337 0.029
sterol homeostasis GO:0055092 4 0.029
oxoacid metabolic process GO:0043436 103 0.029
dna integrity checkpoint GO:0031570 81 0.029
peptidyl proline modification GO:0018208 3 0.029
alcohol biosynthetic process GO:0046165 14 0.028
homeostatic process GO:0042592 199 0.028
mitotic g2 m transition checkpoint GO:0044818 70 0.028
ecdysone biosynthetic process GO:0006697 9 0.027
negative regulation of cellular biosynthetic process GO:0031327 277 0.027
negative regulation of transcription dna templated GO:0045892 237 0.026
organic acid metabolic process GO:0006082 103 0.026
defense response GO:0006952 300 0.026
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.026
sensory perception of chemical stimulus GO:0007606 116 0.026
regulation of protein metabolic process GO:0051246 256 0.025
leg disc development GO:0035218 92 0.025
negative regulation of growth GO:0045926 84 0.025
regulation of cell death GO:0010941 173 0.025
regulation of multicellular organismal development GO:2000026 414 0.025
sensory organ morphogenesis GO:0090596 260 0.024
intracellular signal transduction GO:0035556 300 0.024
humoral immune response GO:0006959 117 0.024
regulation of cellular protein metabolic process GO:0032268 243 0.024
mitotic g2 dna damage checkpoint GO:0007095 69 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.023
organonitrogen compound metabolic process GO:1901564 318 0.023
chromosome organization GO:0051276 360 0.023
regulation of intracellular signal transduction GO:1902531 236 0.023
carboxylic acid metabolic process GO:0019752 92 0.023
organelle assembly GO:0070925 198 0.023
cellular amine metabolic process GO:0044106 12 0.023
negative regulation of gene expression GO:0010629 387 0.023
amine metabolic process GO:0009308 12 0.022
positive regulation of signaling GO:0023056 243 0.022
negative regulation of biosynthetic process GO:0009890 277 0.022
regulation of growth GO:0040008 233 0.022
organic substance transport GO:0071702 257 0.022
regionalization GO:0003002 416 0.022
transition metal ion transport GO:0000041 16 0.022
phosphorylation GO:0016310 294 0.022
organic substance catabolic process GO:1901575 308 0.022
establishment of localization in cell GO:0051649 402 0.022
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.022
imaginal disc pattern formation GO:0007447 91 0.022
immune system process GO:0002376 347 0.021
proteolysis GO:0006508 192 0.021
hormone metabolic process GO:0042445 33 0.021
lipid biosynthetic process GO:0008610 46 0.021
wing disc morphogenesis GO:0007472 344 0.021
negative regulation of cell cycle phase transition GO:1901988 103 0.021
cholesterol homeostasis GO:0042632 3 0.021
segmentation GO:0035282 207 0.021
innate immune response GO:0045087 144 0.021
morphogenesis of an epithelium GO:0002009 276 0.021
regulation of programmed cell death GO:0043067 152 0.020
gland development GO:0048732 191 0.020
salivary gland development GO:0007431 162 0.020
establishment or maintenance of cell polarity GO:0007163 167 0.020
extracellular structure organization GO:0043062 46 0.020
ion transport GO:0006811 145 0.020
immune response GO:0006955 246 0.019
epithelial cell development GO:0002064 274 0.019
regulation of apoptotic process GO:0042981 130 0.019
phagocytosis GO:0006909 215 0.019
developmental growth GO:0048589 280 0.018
single organism intracellular transport GO:1902582 207 0.018
regulation of cell cycle GO:0051726 291 0.018
muscle attachment GO:0016203 36 0.018
programmed cell death GO:0012501 257 0.018
macromolecular complex assembly GO:0065003 256 0.018
regulation of cellular amine metabolic process GO:0033238 3 0.018
regulation of catalytic activity GO:0050790 185 0.018
endomembrane system organization GO:0010256 119 0.018
regulation of protein modification process GO:0031399 112 0.017
response to abiotic stimulus GO:0009628 341 0.017
regulation of cell development GO:0060284 215 0.017
camera type eye morphogenesis GO:0048593 2 0.017
cell cycle phase transition GO:0044770 140 0.017
cellular macromolecule localization GO:0070727 220 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
ecdysone metabolic process GO:0008205 11 0.017
dendrite morphogenesis GO:0048813 199 0.017
cell migration GO:0016477 238 0.017
dna damage checkpoint GO:0000077 78 0.017
intracellular transport GO:0046907 228 0.017
male gamete generation GO:0048232 201 0.017
mapk cascade GO:0000165 107 0.017
regulation of cell cycle phase transition GO:1901987 130 0.017
regulation of cellular ketone metabolic process GO:0010565 3 0.017
epithelial cell differentiation GO:0030855 322 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
imaginal disc derived leg morphogenesis GO:0007480 80 0.016
mrna processing GO:0006397 104 0.016
regulation of molecular function GO:0065009 217 0.016
positive regulation of macromolecule metabolic process GO:0010604 405 0.016
tissue morphogenesis GO:0048729 297 0.016
transcription from rna polymerase ii promoter GO:0006366 368 0.016
spermatogenesis GO:0007283 200 0.016
embryonic pattern specification GO:0009880 174 0.016
columnar cuboidal epithelial cell development GO:0002066 249 0.016
cellular protein localization GO:0034613 160 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
salivary gland morphogenesis GO:0007435 145 0.016
mitotic dna damage checkpoint GO:0044773 74 0.016
salivary gland cell autophagic cell death GO:0035071 83 0.016
regulation of localization GO:0032879 275 0.016
negative regulation of signal transduction GO:0009968 206 0.016
muscle organ development GO:0007517 127 0.016
camera type eye development GO:0043010 4 0.015
negative regulation of cell communication GO:0010648 223 0.015
cell cycle checkpoint GO:0000075 95 0.015
central nervous system development GO:0007417 201 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
morphogenesis of a polarized epithelium GO:0001738 93 0.015
synaptic vesicle transport GO:0048489 50 0.015
cellularization GO:0007349 90 0.015
cell proliferation GO:0008283 299 0.015
positive regulation of cellular amine metabolic process GO:0033240 0 0.015
regulation of transport GO:0051049 181 0.015
response to organic substance GO:0010033 284 0.015
tube morphogenesis GO:0035239 191 0.015
establishment of protein localization GO:0045184 163 0.015
exocrine system development GO:0035272 162 0.015
cholesterol transport GO:0030301 2 0.015
regulation of establishment of planar polarity GO:0090175 22 0.015
locomotory behavior GO:0007626 176 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
cytoplasmic transport GO:0016482 130 0.015
retina development in camera type eye GO:0060041 4 0.015
regulation of synapse structure and activity GO:0050803 128 0.014
tissue death GO:0016271 102 0.014
protein complex biogenesis GO:0070271 201 0.014
cation transport GO:0006812 110 0.014
positive regulation of phosphate metabolic process GO:0045937 139 0.014
protein ubiquitination GO:0016567 70 0.014
pigmentation GO:0043473 75 0.014
protein maturation GO:0051604 71 0.014
developmental pigmentation GO:0048066 68 0.014
mrna metabolic process GO:0016071 124 0.014
ameboidal type cell migration GO:0001667 151 0.014
detection of stimulus GO:0051606 156 0.014
sterol biosynthetic process GO:0016126 9 0.014
regulation of cell proliferation GO:0042127 163 0.014
detection of stimulus involved in sensory perception GO:0050906 92 0.014
notch signaling pathway GO:0007219 120 0.014
microtubule organizing center organization GO:0031023 168 0.014
response to lipopolysaccharide GO:0032496 4 0.014
positive regulation of biosynthetic process GO:0009891 316 0.014
regulation of catabolic process GO:0009894 170 0.014
protein transport GO:0015031 155 0.014
taxis GO:0042330 304 0.014
connective tissue development GO:0061448 3 0.014
positive regulation of cell communication GO:0010647 250 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
purine nucleotide metabolic process GO:0006163 146 0.014
protein catabolic process GO:0030163 101 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
mitotic cell cycle checkpoint GO:0007093 88 0.013
negative regulation of protein metabolic process GO:0051248 85 0.013
leg disc morphogenesis GO:0007478 80 0.013
nuclear division GO:0000280 332 0.013
cellular macromolecule catabolic process GO:0044265 136 0.013
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.013
cell adhesion GO:0007155 136 0.013
single organism catabolic process GO:0044712 228 0.013
response to external biotic stimulus GO:0043207 293 0.013
neurological system process GO:0050877 358 0.013
catabolic process GO:0009056 409 0.013
mushroom body development GO:0016319 70 0.013
tissue migration GO:0090130 155 0.013
positive regulation of nucleic acid templated transcription GO:1903508 266 0.013
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.013
peptidyl amino acid modification GO:0018193 105 0.013
ethanolamine containing compound metabolic process GO:0042439 4 0.013
regulation of cell differentiation GO:0045595 302 0.013
blastoderm segmentation GO:0007350 159 0.013
gastrulation GO:0007369 70 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
response to oxygen containing compound GO:1901700 200 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.013
neuromuscular junction development GO:0007528 149 0.013
protein modification by small protein conjugation or removal GO:0070647 106 0.013
regulation of synapse assembly GO:0051963 94 0.012
regulation of nervous system development GO:0051960 248 0.012
histolysis GO:0007559 102 0.012
actin filament based process GO:0030029 220 0.012
axonogenesis GO:0007409 290 0.012
developmental programmed cell death GO:0010623 138 0.012
cellular catabolic process GO:0044248 372 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
dendrite development GO:0016358 204 0.012
heterocycle catabolic process GO:0046700 166 0.012
single organismal cell cell adhesion GO:0016337 45 0.012
multicellular organismal aging GO:0010259 140 0.012
growth GO:0040007 359 0.012
protein complex assembly GO:0006461 200 0.012
regulation of organelle organization GO:0033043 196 0.012
positive regulation of catabolic process GO:0009896 105 0.012
steroid catabolic process GO:0006706 1 0.012
salivary gland histolysis GO:0035070 88 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
ovarian follicle cell development GO:0030707 248 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
respiratory system development GO:0060541 213 0.011
wound healing GO:0042060 75 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
metal ion homeostasis GO:0055065 44 0.011
positive regulation of signal transduction GO:0009967 223 0.011
open tracheal system development GO:0007424 204 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
nucleus organization GO:0006997 45 0.011
chromatin organization GO:0006325 207 0.011
locomotor rhythm GO:0045475 56 0.011
response to toxic substance GO:0009636 22 0.011
apoptotic process GO:0006915 159 0.011
positive regulation of multicellular organismal process GO:0051240 143 0.011
response to biotic stimulus GO:0009607 294 0.011
transition metal ion homeostasis GO:0055076 17 0.011
extracellular matrix constituent secretion GO:0070278 4 0.011
establishment of tissue polarity GO:0007164 87 0.011
establishment of organelle localization GO:0051656 122 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
limb development GO:0060173 1 0.011
negative regulation of mitotic cell cycle GO:0045930 109 0.011
regulation of phosphate metabolic process GO:0019220 210 0.011
spindle organization GO:0007051 253 0.011
response to other organism GO:0051707 293 0.011
regulation of translation GO:0006417 56 0.011
protein localization to nucleus GO:0034504 55 0.011
cellular nitrogen compound catabolic process GO:0044270 165 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
negative regulation of rna metabolic process GO:0051253 251 0.011
mitotic nuclear division GO:0007067 213 0.011
gland morphogenesis GO:0022612 145 0.011
biological adhesion GO:0022610 138 0.011
positive regulation of cell motility GO:2000147 3 0.011
positive regulation of rna biosynthetic process GO:1902680 266 0.011
regulation of phosphorus metabolic process GO:0051174 210 0.011
long term memory GO:0007616 62 0.011
ras protein signal transduction GO:0007265 88 0.011
tube development GO:0035295 244 0.011
response to organophosphorus GO:0046683 2 0.011
wnt signaling pathway GO:0016055 98 0.010
asymmetric cell division GO:0008356 37 0.010
regulation of hormone levels GO:0010817 40 0.010
mitotic spindle organization GO:0007052 220 0.010
single organism cellular localization GO:1902580 180 0.010
synaptic transmission GO:0007268 288 0.010
regulation of developmental growth GO:0048638 174 0.010
circadian behavior GO:0048512 76 0.010
hindbrain development GO:0030902 2 0.010
cellular response to molecule of bacterial origin GO:0071219 3 0.010
chemosensory behavior GO:0007635 106 0.010
regulation of cell shape GO:0008360 113 0.010
cilium assembly GO:0042384 38 0.010
aromatic compound catabolic process GO:0019439 166 0.010
cellular homeostasis GO:0019725 80 0.010
metal ion transport GO:0030001 74 0.010
positive regulation of phosphorus metabolic process GO:0010562 139 0.010
axis specification GO:0009798 167 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
negative regulation of cell proliferation GO:0008285 69 0.010
synaptic growth at neuromuscular junction GO:0051124 119 0.010
regulation of immune system process GO:0002682 176 0.010
golgi organization GO:0007030 66 0.010
autophagic cell death GO:0048102 83 0.010
purine containing compound metabolic process GO:0072521 155 0.010
negative regulation of cell death GO:0060548 81 0.010
single organism biosynthetic process GO:0044711 206 0.010
protein modification by small protein conjugation GO:0032446 79 0.010
organelle fission GO:0048285 340 0.010
androgen metabolic process GO:0008209 1 0.010

nvd disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.024
disease of metabolism DOID:0014667 0 0.016
nervous system disease DOID:863 0 0.014
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
organ system cancer DOID:0050686 0 0.013
inherited metabolic disorder DOID:655 0 0.012
sensory system disease DOID:0050155 0 0.011
acquired metabolic disease DOID:0060158 0 0.010