Drosophila melanogaster

123 known processes

RecQ5 (Dmel_CG4879)

homolog of RecQ

(Aliases: Q1,Dm RECQ5/QE,dmRecQ5b,DmRECQ5,DQ1,anon-EST:Posey293,CG4879,RECQ5,RECQ5/QE,Dmel\CG4879,RECQE,Dq1)

RecQ5 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
dna recombination GO:0006310 32 0.957
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.944
dna repair GO:0006281 54 0.937
dna metabolic process GO:0006259 227 0.935
reciprocal meiotic recombination GO:0007131 19 0.920
recombinational repair GO:0000725 13 0.918
double strand break repair via homologous recombination GO:0000724 13 0.864
dna geometric change GO:0032392 16 0.821
double strand break repair GO:0006302 26 0.743
meiotic cell cycle GO:0051321 171 0.707
cellular response to dna damage stimulus GO:0006974 223 0.694
dna duplex unwinding GO:0032508 16 0.689
dna synthesis involved in dna repair GO:0000731 5 0.652
dna double strand break processing GO:0000729 3 0.648
meiotic cell cycle process GO:1903046 132 0.638
translesion synthesis GO:0019985 2 0.555
female meiosis chromosome segregation GO:0016321 33 0.517
meiotic chromosome segregation GO:0045132 59 0.509
regulation of dna recombination GO:0000018 4 0.503
nuclear division GO:0000280 332 0.498
female meiotic division GO:0007143 70 0.489
developmental growth GO:0048589 280 0.472
growth GO:0040007 359 0.459
postreplication repair GO:0006301 2 0.415
mitotic g2 dna damage checkpoint GO:0007095 69 0.405
negative regulation of cell cycle phase transition GO:1901988 103 0.347
meiosis i GO:0007127 59 0.324
nucleotide excision repair GO:0006289 8 0.320
double strand break repair via nonhomologous end joining GO:0006303 5 0.309
dna damage checkpoint GO:0000077 78 0.297
dna conformation change GO:0071103 105 0.293
mitotic dna damage checkpoint GO:0044773 74 0.292
cellular response to abiotic stimulus GO:0071214 58 0.291
response to light stimulus GO:0009416 124 0.291
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.259
Human
mitotic cell cycle phase transition GO:0044772 138 0.259
mitotic dna integrity checkpoint GO:0044774 75 0.257
regulation of developmental growth GO:0048638 174 0.234
g2 dna damage checkpoint GO:0031572 69 0.233
cell division GO:0051301 248 0.230
non recombinational repair GO:0000726 7 0.220
male gamete generation GO:0048232 201 0.219
nucleotide metabolic process GO:0009117 161 0.217
negative regulation of rna biosynthetic process GO:1902679 240 0.211
Human
chromosome organization GO:0051276 360 0.172
chromosome separation GO:0051304 42 0.171
Human
response to abiotic stimulus GO:0009628 341 0.165
meiotic nuclear division GO:0007126 151 0.163
reciprocal dna recombination GO:0035825 19 0.159
telomere maintenance via recombination GO:0000722 1 0.152
ribonucleoside triphosphate catabolic process GO:0009203 108 0.152
mitotic g2 m transition checkpoint GO:0044818 70 0.151
regulation of cell cycle GO:0051726 291 0.135
regulation of cell cycle process GO:0010564 181 0.135
response to alkaloid GO:0043279 26 0.134
atp metabolic process GO:0046034 49 0.133
negative regulation of cell cycle process GO:0010948 109 0.132
multicellular organism growth GO:0035264 46 0.131
chromatin organization GO:0006325 207 0.125
gene silencing GO:0016458 138 0.123
aging GO:0007568 143 0.123
Worm
carbohydrate derivative metabolic process GO:1901135 217 0.119
negative regulation of mitotic cell cycle GO:0045930 109 0.115
ribonucleoside monophosphate metabolic process GO:0009161 51 0.114
regulation of cell death GO:0010941 173 0.111
purine nucleotide metabolic process GO:0006163 146 0.109
intracellular signal transduction GO:0035556 300 0.108
organelle fission GO:0048285 340 0.108
nucleobase containing compound catabolic process GO:0034655 165 0.101
vesicle mediated transport GO:0016192 381 0.100
regulation of nuclear division GO:0051783 58 0.100
negative regulation of developmental process GO:0051093 201 0.097
negative regulation of developmental growth GO:0048640 64 0.093
ribonucleoside metabolic process GO:0009119 127 0.091
regulation of intracellular signal transduction GO:1902531 236 0.090
cellular response to radiation GO:0071478 52 0.089
chromatin modification GO:0016568 147 0.087
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.083
Human
eye morphogenesis GO:0048592 260 0.082
nucleoside monophosphate metabolic process GO:0009123 52 0.080
chromosome segregation GO:0007059 157 0.080
regulation of cell cycle phase transition GO:1901987 130 0.080
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.079
death GO:0016265 284 0.078
atp catabolic process GO:0006200 38 0.078
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.076
nucleoside triphosphate catabolic process GO:0009143 108 0.074
regulation of dna metabolic process GO:0051052 34 0.072
mitotic cell cycle checkpoint GO:0007093 88 0.072
regulation of meiosis GO:0040020 3 0.072
ribonucleoside triphosphate metabolic process GO:0009199 119 0.071
negative regulation of cell cycle GO:0045786 116 0.071
homeostatic process GO:0042592 199 0.069
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.068
organonitrogen compound metabolic process GO:1901564 318 0.067
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.067
Human
endocytosis GO:0006897 310 0.067
single organism catabolic process GO:0044712 228 0.066
compound eye development GO:0048749 307 0.065
cell proliferation GO:0008283 299 0.064
organic substance catabolic process GO:1901575 308 0.064
rna splicing GO:0008380 83 0.062
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.062
dna biosynthetic process GO:0071897 24 0.061
positive regulation of developmental process GO:0051094 143 0.060
regulation of mitotic cell cycle phase transition GO:1901990 130 0.059
negative regulation of growth GO:0045926 84 0.059
regulation of cellular response to stress GO:0080135 89 0.058
nucleotide catabolic process GO:0009166 109 0.057
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.057
Human
apoptotic process GO:0006915 159 0.057
organonitrogen compound catabolic process GO:1901565 128 0.055
response to oxidative stress GO:0006979 86 0.054
heterocycle catabolic process GO:0046700 166 0.054
purine ribonucleoside metabolic process GO:0046128 127 0.053
response to uv GO:0009411 24 0.053
regulation of organelle organization GO:0033043 196 0.053
purine ribonucleoside catabolic process GO:0046130 112 0.053
sex differentiation GO:0007548 81 0.053
mitotic sister chromatid segregation GO:0000070 87 0.052
eye development GO:0001654 323 0.050
regulation of multicellular organism growth GO:0040014 40 0.050
response to purine containing compound GO:0014074 12 0.050
cellular catabolic process GO:0044248 372 0.049
cell death GO:0008219 279 0.049
signal transduction in response to dna damage GO:0042770 3 0.049
purine ribonucleotide metabolic process GO:0009150 145 0.047
dna replication GO:0006260 48 0.046
Human
cellular response to ionizing radiation GO:0071479 15 0.046
ribose phosphate metabolic process GO:0019693 145 0.045
response to organic substance GO:0010033 284 0.044
negative regulation of rna metabolic process GO:0051253 251 0.044
Human
cellular response to gamma radiation GO:0071480 10 0.044
regulation of hydrolase activity GO:0051336 97 0.044
negative regulation of response to stimulus GO:0048585 258 0.044
ribonucleoside monophosphate catabolic process GO:0009158 39 0.044
carbohydrate derivative catabolic process GO:1901136 118 0.042
regulation of double strand break repair GO:2000779 3 0.042
telomere capping GO:0016233 11 0.041
larval development GO:0002164 104 0.041
sensory organ morphogenesis GO:0090596 260 0.040
embryo development ending in birth or egg hatching GO:0009792 152 0.040
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.040
positive regulation of hydrolase activity GO:0051345 78 0.040
multicellular organismal aging GO:0010259 140 0.040
Worm
response to organic cyclic compound GO:0014070 89 0.040
ribonucleoside catabolic process GO:0042454 112 0.040
negative regulation of cellular metabolic process GO:0031324 382 0.040
Human
spermatogenesis GO:0007283 200 0.039
cellular response to chemical stimulus GO:0070887 199 0.039
nucleobase containing small molecule metabolic process GO:0055086 174 0.039
appendage morphogenesis GO:0035107 397 0.039
dna dependent dna replication GO:0006261 17 0.038
negative regulation of cell cycle g2 m phase transition GO:1902750 8 0.038
covalent chromatin modification GO:0016569 106 0.037
regulation of programmed cell death GO:0043067 152 0.037
negative regulation of cell communication GO:0010648 223 0.037
immune response GO:0006955 246 0.036
programmed cell death GO:0012501 257 0.036
purine nucleotide catabolic process GO:0006195 109 0.035
regulation of response to stress GO:0080134 200 0.035
positive regulation of phosphorus metabolic process GO:0010562 139 0.035
single organism biosynthetic process GO:0044711 206 0.035
positive regulation of programmed cell death GO:0043068 62 0.034
small gtpase mediated signal transduction GO:0007264 88 0.033
stress activated protein kinase signaling cascade GO:0031098 55 0.033
response to ionizing radiation GO:0010212 32 0.033
cellular nitrogen compound catabolic process GO:0044270 165 0.032
nucleoside catabolic process GO:0009164 112 0.032
cellular protein modification process GO:0006464 438 0.032
regulation of cell division GO:0051302 72 0.031
organophosphate metabolic process GO:0019637 195 0.031
purine nucleoside catabolic process GO:0006152 112 0.031
germarium derived egg chamber formation GO:0007293 101 0.031
mitotic nuclear division GO:0007067 213 0.031
response to radiation GO:0009314 155 0.030
purine nucleoside triphosphate metabolic process GO:0009144 119 0.030
regulation of small gtpase mediated signal transduction GO:0051056 93 0.030
cell cycle phase transition GO:0044770 140 0.029
central nervous system development GO:0007417 201 0.029
histone modification GO:0016570 106 0.029
regulation of dna repair GO:0006282 5 0.029
post embryonic appendage morphogenesis GO:0035120 385 0.029
telomere organization GO:0032200 21 0.028
nucleoside triphosphate metabolic process GO:0009141 120 0.028
dorsal ventral axis specification GO:0009950 66 0.027
ribonucleotide metabolic process GO:0009259 145 0.027
brain development GO:0007420 120 0.027
purine ribonucleotide catabolic process GO:0009154 109 0.027
positive regulation of endopeptidase activity GO:0010950 26 0.027
purine nucleoside monophosphate catabolic process GO:0009128 38 0.027
regulation of phosphate metabolic process GO:0019220 210 0.027
regionalization GO:0003002 416 0.026
positive regulation of molecular function GO:0044093 136 0.026
cellular macromolecule catabolic process GO:0044265 136 0.026
regulation of cytoskeleton organization GO:0051493 89 0.026
organic cyclic compound catabolic process GO:1901361 168 0.025
nucleoside phosphate metabolic process GO:0006753 162 0.025
regulation of cell size GO:0008361 63 0.025
positive regulation of apoptotic process GO:0043065 47 0.025
chromatin silencing GO:0006342 76 0.025
positive regulation of multicellular organismal process GO:0051240 143 0.025
response to organonitrogen compound GO:0010243 75 0.025
negative regulation of nucleic acid templated transcription GO:1903507 240 0.025
Human
glycosyl compound catabolic process GO:1901658 112 0.024
imaginal disc derived appendage development GO:0048737 399 0.024
imaginal disc derived wing morphogenesis GO:0007476 337 0.024
reproductive structure development GO:0048608 74 0.023
purine nucleoside monophosphate metabolic process GO:0009126 50 0.023
regulation of growth GO:0040008 233 0.023
single organism intracellular transport GO:1902582 207 0.022
negative regulation of signal transduction GO:0009968 206 0.022
immune system process GO:0002376 347 0.022
cell aging GO:0007569 2 0.022
dna integrity checkpoint GO:0031570 81 0.022
centrosome duplication GO:0051298 121 0.021
positive regulation of cell death GO:0010942 69 0.021
regulation of phosphorus metabolic process GO:0051174 210 0.021
protein complex assembly GO:0006461 200 0.021
response to nitrogen compound GO:1901698 90 0.021
protein modification process GO:0036211 438 0.021
response to gamma radiation GO:0010332 17 0.019
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.019
ion transport GO:0006811 145 0.019
dendrite development GO:0016358 204 0.019
jnk cascade GO:0007254 50 0.019
regulation of nucleoside metabolic process GO:0009118 50 0.019
organophosphate catabolic process GO:0046434 112 0.018
cellular response to organic substance GO:0071310 132 0.018
positive regulation of catalytic activity GO:0043085 118 0.018
macromolecular complex assembly GO:0065003 256 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
negative regulation of signaling GO:0023057 219 0.018
response to external biotic stimulus GO:0043207 293 0.018
nuclear transport GO:0051169 72 0.017
immune response activating signal transduction GO:0002757 2 0.017
gtp catabolic process GO:0006184 72 0.017
germarium derived oocyte fate determination GO:0007294 26 0.017
compound eye morphogenesis GO:0001745 249 0.017
regulation of cell proliferation GO:0042127 163 0.016
centrosome cycle GO:0007098 137 0.016
proteolysis GO:0006508 192 0.016
purine containing compound catabolic process GO:0072523 112 0.016
cell cycle checkpoint GO:0000075 95 0.016
sister chromatid segregation GO:0000819 92 0.016
wing disc morphogenesis GO:0007472 344 0.016
macromolecule catabolic process GO:0009057 161 0.016
anatomical structure homeostasis GO:0060249 97 0.015
regulation of apoptotic process GO:0042981 130 0.015
response to biotic stimulus GO:0009607 294 0.015
muscle structure development GO:0061061 224 0.015
locomotory behavior GO:0007626 176 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
single organism membrane organization GO:0044802 93 0.014
positive regulation of immune system process GO:0002684 68 0.014
negative regulation of transcription dna templated GO:0045892 237 0.014
Human
alternative mrna splicing via spliceosome GO:0000380 60 0.014
aggressive behavior GO:0002118 63 0.014
negative regulation of cell differentiation GO:0045596 143 0.014
nucleoside phosphate catabolic process GO:1901292 110 0.014
monocarboxylic acid transport GO:0015718 3 0.013
sensory perception of pain GO:0019233 4 0.013
cellular macromolecular complex assembly GO:0034622 153 0.013
nucleoside monophosphate catabolic process GO:0009125 39 0.013
protein complex biogenesis GO:0070271 201 0.013
oocyte dorsal ventral axis specification GO:0007310 34 0.013
regulation of rna splicing GO:0043484 69 0.013
nucleoside metabolic process GO:0009116 127 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
Human
protein localization GO:0008104 284 0.013
regulation of purine nucleotide catabolic process GO:0033121 48 0.013
purine nucleoside triphosphate catabolic process GO:0009146 108 0.013
mushroom body development GO:0016319 70 0.013
defense response GO:0006952 300 0.012
establishment of tissue polarity GO:0007164 87 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
regulation of mitotic cell cycle GO:0007346 190 0.012
syncytium formation GO:0006949 43 0.012
establishment of ommatidial planar polarity GO:0042067 49 0.011
purine containing compound metabolic process GO:0072521 155 0.011
ras protein signal transduction GO:0007265 88 0.011
positive regulation of growth GO:0045927 75 0.011
regulation of purine nucleotide metabolic process GO:1900542 62 0.011
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.011
small molecule metabolic process GO:0044281 305 0.011
regulation of cell differentiation GO:0045595 302 0.011
dna amplification GO:0006277 11 0.011
positive regulation of gene expression GO:0010628 290 0.011
regulation of stress activated protein kinase signaling cascade GO:0070302 42 0.011
intra s dna damage checkpoint GO:0031573 2 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
gonad development GO:0008406 50 0.011
positive regulation of cellular biosynthetic process GO:0031328 316 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
positive regulation of signaling GO:0023056 243 0.010
forebrain development GO:0030900 2 0.010
development of primary sexual characteristics GO:0045137 50 0.010
developmental growth involved in morphogenesis GO:0060560 65 0.010
negative regulation of nervous system development GO:0051961 92 0.010

RecQ5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
organ system cancer DOID:0050686 0 0.032
disease of cellular proliferation DOID:14566 0 0.032
cancer DOID:162 0 0.032
disease of anatomical entity DOID:7 0 0.021
musculoskeletal system cancer DOID:0060100 0 0.021
thoracic cancer DOID:5093 0 0.015
disease of metabolism DOID:0014667 0 0.013