Drosophila melanogaster

30 known processes

Spx (Dmel_CG3780)

Spliceosomal protein on the X

(Aliases: SPX,Dmel\CG3780,CG3780,spx)

Spx biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
negative regulation of rna metabolic process GO:0051253 251 0.618
chromosome organization GO:0051276 360 0.531
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.472
Mouse
transcription from rna polymerase ii promoter GO:0006366 368 0.445
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.439
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.297
Mouse
negative regulation of cellular metabolic process GO:0031324 382 0.282
cell proliferation GO:0008283 299 0.231
negative regulation of rna biosynthetic process GO:1902679 240 0.222
developmental growth GO:0048589 280 0.207
negative regulation of nucleic acid templated transcription GO:1903507 240 0.198
positive regulation of biosynthetic process GO:0009891 316 0.196
sister chromatid segregation GO:0000819 92 0.185
regulation of cell proliferation GO:0042127 163 0.182
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.167
negative regulation of biosynthetic process GO:0009890 277 0.158
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.156
positive regulation of macromolecule metabolic process GO:0010604 405 0.155
Mouse
positive regulation of rna metabolic process GO:0051254 271 0.151
Mouse
positive regulation of transcription dna templated GO:0045893 266 0.145
intracellular transport GO:0046907 228 0.140
chromatin organization GO:0006325 207 0.140
negative regulation of transcription dna templated GO:0045892 237 0.139
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.138
positive regulation of nucleic acid templated transcription GO:1903508 266 0.137
establishment of localization in cell GO:0051649 402 0.135
endocytosis GO:0006897 310 0.133
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.125
mitotic sister chromatid segregation GO:0000070 87 0.114
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.113
positive regulation of gene expression GO:0010628 290 0.110
Mouse
negative regulation of gene expression GO:0010629 387 0.106
chromatin modification GO:0016568 147 0.096
protein localization GO:0008104 284 0.093
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.089
regulation of cell cycle g1 s phase transition GO:1902806 23 0.085
wing disc morphogenesis GO:0007472 344 0.077
negative regulation of cellular component organization GO:0051129 108 0.075
positive regulation of rna biosynthetic process GO:1902680 266 0.074
chromosome segregation GO:0007059 157 0.068
positive regulation of cellular biosynthetic process GO:0031328 316 0.059
nucleocytoplasmic transport GO:0006913 72 0.058
male gamete generation GO:0048232 201 0.057
negative regulation of cellular biosynthetic process GO:0031327 277 0.056
cellular catabolic process GO:0044248 372 0.055
post embryonic appendage morphogenesis GO:0035120 385 0.053
cellular protein localization GO:0034613 160 0.048
regulation of cell cycle GO:0051726 291 0.047
regulation of localization GO:0032879 275 0.046
rna processing GO:0006396 147 0.043
Mouse
histone modification GO:0016570 106 0.041
covalent chromatin modification GO:0016569 106 0.041
organelle localization GO:0051640 148 0.040
cellular macromolecule localization GO:0070727 220 0.040
nuclear division GO:0000280 332 0.040
regulation of organelle organization GO:0033043 196 0.039
mrna metabolic process GO:0016071 124 0.039
Mouse
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.038
positive regulation of cell proliferation GO:0008284 47 0.038
protein transport GO:0015031 155 0.038
regulation of programmed cell death GO:0043067 152 0.037
mitotic spindle organization GO:0007052 220 0.037
organelle fission GO:0048285 340 0.034
regulation of catalytic activity GO:0050790 185 0.033
centrosome duplication GO:0051298 121 0.032
anterior posterior pattern specification GO:0009952 136 0.031
programmed cell death GO:0012501 257 0.030
cellular response to chemical stimulus GO:0070887 199 0.030
nucleoside metabolic process GO:0009116 127 0.030
axon development GO:0061564 297 0.030
gene silencing GO:0016458 138 0.030
mrna processing GO:0006397 104 0.030
Mouse
regulation of catabolic process GO:0009894 170 0.030
nucleoside phosphate catabolic process GO:1901292 110 0.030
aromatic compound catabolic process GO:0019439 166 0.030
cell death GO:0008219 279 0.029
vesicle mediated transport GO:0016192 381 0.028
nucleoside triphosphate metabolic process GO:0009141 120 0.028
centrosome organization GO:0051297 163 0.028
axis specification GO:0009798 167 0.027
appendage development GO:0048736 401 0.027
imaginal disc derived appendage development GO:0048737 399 0.027
modification dependent macromolecule catabolic process GO:0043632 79 0.027
establishment of organelle localization GO:0051656 122 0.027
negative regulation of cell differentiation GO:0045596 143 0.026
regulation of chromosome organization GO:0033044 64 0.026
purine ribonucleoside catabolic process GO:0046130 112 0.025
regulation of cellular localization GO:0060341 136 0.025
mitotic nuclear division GO:0007067 213 0.025
regulation of cell development GO:0060284 215 0.025
positive regulation of intracellular signal transduction GO:1902533 116 0.024
tube development GO:0035295 244 0.024
regulation of molecular function GO:0065009 217 0.023
regulation of mrna splicing via spliceosome GO:0048024 64 0.023
Mouse
taxis GO:0042330 304 0.023
organic substance catabolic process GO:1901575 308 0.023
embryo development ending in birth or egg hatching GO:0009792 152 0.022
extracellular matrix assembly GO:0085029 13 0.022
cell division GO:0051301 248 0.022
regulation of nervous system development GO:0051960 248 0.021
anterior posterior axis specification GO:0009948 109 0.021
dendrite development GO:0016358 204 0.021
regulation of mrna metabolic process GO:1903311 72 0.021
Mouse
regulation of cellular component biogenesis GO:0044087 201 0.021
body morphogenesis GO:0010171 2 0.021
organic substance transport GO:0071702 257 0.020
mrna splicing via spliceosome GO:0000398 73 0.020
Mouse
embryonic pattern specification GO:0009880 174 0.020
purine nucleotide catabolic process GO:0006195 109 0.019
regulation of cell death GO:0010941 173 0.019
regulation of protein catabolic process GO:0042176 55 0.019
positive regulation of cellular component organization GO:0051130 156 0.019
regulation of protein metabolic process GO:0051246 256 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
regulation of neuron differentiation GO:0045664 103 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
dendrite morphogenesis GO:0048813 199 0.019
regulation of mitotic cell cycle phase transition GO:1901990 130 0.018
cell cycle g1 s phase transition GO:0044843 31 0.018
regulation of protein localization GO:0032880 76 0.018
regulation of cell differentiation GO:0045595 302 0.018
ubiquitin dependent protein catabolic process GO:0006511 78 0.018
apoptotic process GO:0006915 159 0.018
dna packaging GO:0006323 91 0.018
protein phosphorylation GO:0006468 169 0.018
regulation of g1 s transition of mitotic cell cycle GO:2000045 23 0.018
regulation of proteolysis involved in cellular protein catabolic process GO:1903050 44 0.018
regulation of multicellular organismal development GO:2000026 414 0.018
ribonucleotide catabolic process GO:0009261 109 0.018
phagocytosis GO:0006909 215 0.017
nucleotide catabolic process GO:0009166 109 0.017
cell cycle phase transition GO:0044770 140 0.017
microtubule organizing center organization GO:0031023 168 0.017
imaginal disc derived wing morphogenesis GO:0007476 337 0.017
organonitrogen compound catabolic process GO:1901565 128 0.017
regulation of dna metabolic process GO:0051052 34 0.017
regulation of cytoskeleton organization GO:0051493 89 0.017
ribonucleoside triphosphate catabolic process GO:0009203 108 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
purine nucleoside triphosphate catabolic process GO:0009146 108 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
purine ribonucleoside metabolic process GO:0046128 127 0.016
epithelial cell development GO:0002064 274 0.016
catabolic process GO:0009056 409 0.016
guanosine containing compound metabolic process GO:1901068 74 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
spermatogenesis GO:0007283 200 0.016
protein catabolic process GO:0030163 101 0.016
rna splicing via transesterification reactions GO:0000375 73 0.016
Mouse
heterocycle catabolic process GO:0046700 166 0.016
cellular response to uv GO:0034644 12 0.016
gtp metabolic process GO:0046039 72 0.016
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.015
spindle organization GO:0007051 253 0.015
regulation of gtp catabolic process GO:0033124 44 0.015
regulation of hydrolase activity GO:0051336 97 0.015
purine nucleoside metabolic process GO:0042278 127 0.015
purine nucleoside catabolic process GO:0006152 112 0.015
death GO:0016265 284 0.014
negative regulation of cell cycle process GO:0010948 109 0.014
g1 s transition of mitotic cell cycle GO:0000082 31 0.014
purine nucleoside triphosphate metabolic process GO:0009144 119 0.014
mitotic spindle elongation GO:0000022 81 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
appendage morphogenesis GO:0035107 397 0.014
cellular nitrogen compound catabolic process GO:0044270 165 0.014
cytoplasmic transport GO:0016482 130 0.014
regulation of nucleotide catabolic process GO:0030811 48 0.014
nuclear transport GO:0051169 72 0.014
mitotic cell cycle embryonic GO:0045448 38 0.013
protein modification process GO:0036211 438 0.013
negative regulation of organelle organization GO:0010639 56 0.013
columnar cuboidal epithelial cell development GO:0002066 249 0.013
mitotic cell cycle phase transition GO:0044772 138 0.013
imaginal disc derived leg morphogenesis GO:0007480 80 0.013
ribonucleoside metabolic process GO:0009119 127 0.013
regulation of gene expression epigenetic GO:0040029 128 0.013
leg disc morphogenesis GO:0007478 80 0.013
morphogenesis of an epithelium GO:0002009 276 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
purine containing compound metabolic process GO:0072521 155 0.013
purine ribonucleotide catabolic process GO:0009154 109 0.013
regulation of developmental growth GO:0048638 174 0.013
imaginal disc derived appendage morphogenesis GO:0035114 395 0.012
regulation of transport GO:0051049 181 0.012
regulation of intracellular transport GO:0032386 64 0.012
cell cycle checkpoint GO:0000075 95 0.012
macromolecular complex assembly GO:0065003 256 0.012
chromatin assembly GO:0031497 48 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
regionalization GO:0003002 416 0.012
negative regulation of cell communication GO:0010648 223 0.012
regulation of microtubule cytoskeleton organization GO:0070507 41 0.012
organophosphate catabolic process GO:0046434 112 0.012
regulation of cellular protein metabolic process GO:0032268 243 0.012
negative regulation of gene expression epigenetic GO:0045814 77 0.012
dna metabolic process GO:0006259 227 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
cellular macromolecular complex assembly GO:0034622 153 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
neuron projection guidance GO:0097485 241 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
nucleotide metabolic process GO:0009117 161 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.011
carboxylic acid metabolic process GO:0019752 92 0.011
regulation of growth GO:0040008 233 0.011
negative regulation of signal transduction GO:0009968 206 0.011
cellular protein modification process GO:0006464 438 0.011
response to extracellular stimulus GO:0009991 116 0.011
organic cyclic compound catabolic process GO:1901361 168 0.011
cellular ketone metabolic process GO:0042180 24 0.011
generation of precursor metabolites and energy GO:0006091 42 0.011
positive regulation of cell cycle process GO:0090068 28 0.011
axonogenesis GO:0007409 290 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
phosphorylation GO:0016310 294 0.010
regulation of cell cycle phase transition GO:1901987 130 0.010
negative regulation of developmental process GO:0051093 201 0.010
cellular amine metabolic process GO:0044106 12 0.010
branching involved in open tracheal system development GO:0060446 45 0.010
proteasomal protein catabolic process GO:0010498 59 0.010
establishment of protein localization GO:0045184 163 0.010
single organism biosynthetic process GO:0044711 206 0.010
cellular amino acid metabolic process GO:0006520 61 0.010

Spx disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org