Drosophila melanogaster

0 known processes

CG8449 (Dmel_CG8449)

CG8449 gene product from transcript CG8449-RA

(Aliases: Dmel\CG8449)

CG8449 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
anion homeostasis GO:0055081 3 0.127
small molecule metabolic process GO:0044281 305 0.076
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.068
organonitrogen compound metabolic process GO:1901564 318 0.058
catabolic process GO:0009056 409 0.057
post embryonic appendage morphogenesis GO:0035120 385 0.050
response to biotic stimulus GO:0009607 294 0.050
organic substance catabolic process GO:1901575 308 0.048
taxis GO:0042330 304 0.048
negative regulation of rna biosynthetic process GO:1902679 240 0.048
exocrine system development GO:0035272 162 0.047
response to organic substance GO:0010033 284 0.047
axon guidance GO:0007411 233 0.046
dendrite development GO:0016358 204 0.046
oxoacid metabolic process GO:0043436 103 0.045
cellular catabolic process GO:0044248 372 0.044
protein modification process GO:0036211 438 0.043
neutral lipid biosynthetic process GO:0046460 2 0.043
carbohydrate derivative metabolic process GO:1901135 217 0.043
neurological system process GO:0050877 358 0.043
sensory perception GO:0007600 196 0.043
organic acid metabolic process GO:0006082 103 0.043
positive regulation of signaling GO:0023056 243 0.042
regulation of localization GO:0032879 275 0.042
gland morphogenesis GO:0022612 145 0.042
ethanolamine containing compound metabolic process GO:0042439 4 0.041
negative regulation of rna metabolic process GO:0051253 251 0.041
developmental growth GO:0048589 280 0.041
response to abiotic stimulus GO:0009628 341 0.040
gene silencing GO:0016458 138 0.040
imaginal disc derived appendage morphogenesis GO:0035114 395 0.040
negative regulation of biosynthetic process GO:0009890 277 0.039
imaginal disc derived wing morphogenesis GO:0007476 337 0.038
cellular protein modification process GO:0006464 438 0.038
sensory perception of chemical stimulus GO:0007606 116 0.038
negative regulation of cellular metabolic process GO:0031324 382 0.038
proteolysis GO:0006508 192 0.038
appendage development GO:0048736 401 0.038
cellular response to dna damage stimulus GO:0006974 223 0.038
imaginal disc derived appendage development GO:0048737 399 0.037
growth GO:0040007 359 0.037
positive regulation of response to stimulus GO:0048584 323 0.036
cellular response to chemical stimulus GO:0070887 199 0.036
negative regulation of gene expression epigenetic GO:0045814 77 0.036
positive regulation of multicellular organismal process GO:0051240 143 0.036
cell migration GO:0016477 238 0.035
phospholipid homeostasis GO:0055091 1 0.035
regulation of sequestering of triglyceride GO:0010889 3 0.035
negative regulation of gene expression GO:0010629 387 0.034
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.034
carboxylic acid metabolic process GO:0019752 92 0.034
steroid catabolic process GO:0006706 1 0.034
response to external biotic stimulus GO:0043207 293 0.032
organophosphate metabolic process GO:0019637 195 0.032
negative regulation of transcription dna templated GO:0045892 237 0.032
chromatin silencing GO:0006342 76 0.032
positive regulation of cell migration GO:0030335 2 0.032
salivary gland morphogenesis GO:0007435 145 0.031
salivary gland development GO:0007431 162 0.031
cholesterol homeostasis GO:0042632 3 0.031
wing disc morphogenesis GO:0007472 344 0.031
triglyceride biosynthetic process GO:0019432 2 0.031
response to bacterium GO:0009617 198 0.030
positive regulation of cell motility GO:2000147 3 0.030
cellular amino acid metabolic process GO:0006520 61 0.030
establishment of localization in cell GO:0051649 402 0.030
organic substance transport GO:0071702 257 0.030
regionalization GO:0003002 416 0.030
developmental programmed cell death GO:0010623 138 0.030
carbohydrate derivative biosynthetic process GO:1901137 85 0.030
gland development GO:0048732 191 0.029
amine metabolic process GO:0009308 12 0.029
cellular lipid metabolic process GO:0044255 83 0.029
lipid metabolic process GO:0006629 121 0.029
cellular modified amino acid metabolic process GO:0006575 45 0.029
dna metabolic process GO:0006259 227 0.029
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.028
cell motility GO:0048870 251 0.028
appendage morphogenesis GO:0035107 397 0.028
single organism catabolic process GO:0044712 228 0.028
sterol homeostasis GO:0055092 4 0.028
small molecule biosynthetic process GO:0044283 37 0.027
ameboidal type cell migration GO:0001667 151 0.027
vesicle mediated transport GO:0016192 381 0.027
cellular macromolecule localization GO:0070727 220 0.026
acylglycerol catabolic process GO:0046464 3 0.026
sulfur compound metabolic process GO:0006790 59 0.026
localization of cell GO:0051674 257 0.026
cellular amine metabolic process GO:0044106 12 0.026
spermatogenesis GO:0007283 200 0.026
alditol phosphate metabolic process GO:0052646 2 0.026
chemotaxis GO:0006935 249 0.026
acylglycerol biosynthetic process GO:0046463 2 0.026
transcription from rna polymerase ii promoter GO:0006366 368 0.026
triglyceride catabolic process GO:0019433 3 0.026
single organism biosynthetic process GO:0044711 206 0.026
cholesterol transport GO:0030301 2 0.025
phagocytosis GO:0006909 215 0.025
regulation of cell cycle GO:0051726 291 0.025
endocytosis GO:0006897 310 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
digestive tract development GO:0048565 149 0.024
sensory perception of smell GO:0007608 80 0.024
homeostatic process GO:0042592 199 0.024
secondary metabolic process GO:0019748 75 0.024
regulation of multicellular organismal development GO:2000026 414 0.024
regulation of gene expression epigenetic GO:0040029 128 0.023
establishment of protein localization GO:0045184 163 0.023
response to oxygen containing compound GO:1901700 200 0.023
regulation of phosphate metabolic process GO:0019220 210 0.023
positive regulation of cell communication GO:0010647 250 0.023
neuron projection guidance GO:0097485 241 0.023
organic hydroxy compound metabolic process GO:1901615 83 0.023
organelle fission GO:0048285 340 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
response to other organism GO:0051707 293 0.023
tissue death GO:0016271 102 0.023
axon development GO:0061564 297 0.022
response to lipopolysaccharide GO:0032496 4 0.022
positive regulation of lipid storage GO:0010884 4 0.022
purine containing compound metabolic process GO:0072521 155 0.022
positive regulation of intracellular signal transduction GO:1902533 116 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
body morphogenesis GO:0010171 2 0.022
medium chain fatty acid metabolic process GO:0051791 1 0.022
dendrite morphogenesis GO:0048813 199 0.022
single organism intracellular transport GO:1902582 207 0.022
cellular ketone metabolic process GO:0042180 24 0.022
phosphatidylethanolamine metabolic process GO:0046337 1 0.022
positive regulation of developmental process GO:0051094 143 0.021
phosphorylation GO:0016310 294 0.021
chromosome organization GO:0051276 360 0.021
axonogenesis GO:0007409 290 0.021
response to temperature stimulus GO:0009266 106 0.021
histolysis GO:0007559 102 0.021
negative regulation of nucleic acid templated transcription GO:1903507 240 0.021
regulation of cellular ketone metabolic process GO:0010565 3 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
eye development GO:0001654 323 0.021
protein localization GO:0008104 284 0.020
xenobiotic catabolic process GO:0042178 1 0.020
defense response to other organism GO:0098542 225 0.020
response to organophosphorus GO:0046683 2 0.020
intracellular protein transport GO:0006886 104 0.020
regulation of transport GO:0051049 181 0.020
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.020
cell death GO:0008219 279 0.020
salivary gland cell autophagic cell death GO:0035071 83 0.020
organophosphate catabolic process GO:0046434 112 0.019
protein complex assembly GO:0006461 200 0.019
substrate adhesion dependent cell spreading GO:0034446 2 0.019
regulation of small gtpase mediated signal transduction GO:0051056 93 0.019
glycerolipid catabolic process GO:0046503 3 0.019
glycoprotein metabolic process GO:0009100 41 0.019
positive regulation of phosphate metabolic process GO:0045937 139 0.019
regulation of ras protein signal transduction GO:0046578 93 0.019
immune response regulating signaling pathway GO:0002764 2 0.019
regulation of growth GO:0040008 233 0.019
response to nitrogen compound GO:1901698 90 0.019
tube development GO:0035295 244 0.019
kidney development GO:0001822 3 0.019
salivary gland histolysis GO:0035070 88 0.018
response to light stimulus GO:0009416 124 0.018
protein complex biogenesis GO:0070271 201 0.018
regulation of cell death GO:0010941 173 0.018
purine nucleotide catabolic process GO:0006195 109 0.018
positive regulation of sequestering of triglyceride GO:0010890 1 0.018
positive regulation of signal transduction GO:0009967 223 0.018
protein transport GO:0015031 155 0.018
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.018
immune response activating signal transduction GO:0002757 2 0.018
nuclear division GO:0000280 332 0.018
forebrain development GO:0030900 2 0.018
small gtpase mediated signal transduction GO:0007264 88 0.018
glycoprotein biosynthetic process GO:0009101 41 0.018
mitotic nuclear division GO:0007067 213 0.017
single organism behavior GO:0044708 391 0.017
cell proliferation GO:0008283 299 0.017
regulation of synapse organization GO:0050807 110 0.017
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.017
autophagic cell death GO:0048102 83 0.017
response to copper ion GO:0046688 4 0.017
response to nutrient levels GO:0031667 114 0.017
heterocycle catabolic process GO:0046700 166 0.017
regulation of immune system process GO:0002682 176 0.017
regulation of cellular amine metabolic process GO:0033238 3 0.017
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.017
aromatic compound catabolic process GO:0019439 166 0.017
nucleoside phosphate metabolic process GO:0006753 162 0.017
cellular protein localization GO:0034613 160 0.017
purine ribonucleotide metabolic process GO:0009150 145 0.017
organic cyclic compound catabolic process GO:1901361 168 0.017
regulation of developmental growth GO:0048638 174 0.017
somatic muscle development GO:0007525 66 0.016
toxin metabolic process GO:0009404 2 0.016
intracellular signal transduction GO:0035556 300 0.016
organelle assembly GO:0070925 198 0.016
eye morphogenesis GO:0048592 260 0.016
response to organic cyclic compound GO:0014070 89 0.016
leg disc development GO:0035218 92 0.016
sulfur compound biosynthetic process GO:0044272 16 0.016
polyol biosynthetic process GO:0046173 3 0.016
cellular response to organic substance GO:0071310 132 0.016
vitamin metabolic process GO:0006766 2 0.016
regulation of phosphorus metabolic process GO:0051174 210 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
regulation of cell proliferation GO:0042127 163 0.016
macromolecular complex assembly GO:0065003 256 0.016
regulation of lipid transport GO:0032368 3 0.016
compound eye development GO:0048749 307 0.016
telencephalon development GO:0021537 2 0.016
camera type eye development GO:0043010 4 0.016
male gamete generation GO:0048232 201 0.016
regulation of anatomical structure size GO:0090066 163 0.016
spermatid differentiation GO:0048515 114 0.016
defense response to bacterium GO:0042742 178 0.016
muscle structure development GO:0061061 224 0.016
glycosyl compound metabolic process GO:1901657 127 0.015
compound eye morphogenesis GO:0001745 249 0.015
glycerolipid metabolic process GO:0046486 34 0.015
fat soluble vitamin metabolic process GO:0006775 1 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
ribonucleotide metabolic process GO:0009259 145 0.015
regulation of mitotic cell cycle GO:0007346 190 0.015
positive regulation of phosphorus metabolic process GO:0010562 139 0.015
olfactory behavior GO:0042048 97 0.015
neutral lipid catabolic process GO:0046461 3 0.015
cellular protein catabolic process GO:0044257 83 0.015
lipid catabolic process GO:0016042 21 0.015
neutral lipid metabolic process GO:0006638 12 0.015
purine ribonucleoside metabolic process GO:0046128 127 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
response to endoplasmic reticulum stress GO:0034976 28 0.015
nucleobase containing small molecule metabolic process GO:0055086 174 0.015
positive regulation of catabolic process GO:0009896 105 0.015
maintenance of location GO:0051235 73 0.015
ras protein signal transduction GO:0007265 88 0.014
hormone catabolic process GO:0042447 3 0.014
dorsal ventral pattern formation GO:0009953 133 0.014
fat soluble vitamin biosynthetic process GO:0042362 1 0.014
response to endogenous stimulus GO:0009719 119 0.014
response to acid chemical GO:0001101 25 0.014
response to wounding GO:0009611 94 0.014
limb development GO:0060173 1 0.014
carbohydrate metabolic process GO:0005975 82 0.014
sensory organ morphogenesis GO:0090596 260 0.014
death GO:0016265 284 0.014
vitamin biosynthetic process GO:0009110 1 0.014
mapk cascade GO:0000165 107 0.014
regulation of apoptotic process GO:0042981 130 0.014
synaptic transmission GO:0007268 288 0.014
ribonucleoside metabolic process GO:0009119 127 0.014
memory GO:0007613 94 0.014
cell cycle phase transition GO:0044770 140 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
detection of stimulus GO:0051606 156 0.014
spindle organization GO:0007051 253 0.014
detection of chemical stimulus GO:0009593 93 0.014
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
secretion GO:0046903 109 0.014
androgen metabolic process GO:0008209 1 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.013
hindbrain development GO:0030902 2 0.013
macromolecule catabolic process GO:0009057 161 0.013
protein catabolic process GO:0030163 101 0.013
segmentation GO:0035282 207 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
mitotic dna integrity checkpoint GO:0044774 75 0.013
mitotic g2 m transition checkpoint GO:0044818 70 0.013
gliogenesis GO:0042063 80 0.013
epithelial cell development GO:0002064 274 0.013
wnt signaling pathway GO:0016055 98 0.013
membrane organization GO:0061024 112 0.013
immune response GO:0006955 246 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
positive regulation of developmental growth GO:0048639 62 0.013
mitotic spindle organization GO:0007052 220 0.013
carbohydrate derivative catabolic process GO:1901136 118 0.013
endomembrane system organization GO:0010256 119 0.013
mitotic dna damage checkpoint GO:0044773 74 0.013
epithelial cell differentiation GO:0030855 322 0.013
chemosensory behavior GO:0007635 106 0.013
regulation of cellular localization GO:0060341 136 0.013
open tracheal system development GO:0007424 204 0.013
single organism membrane organization GO:0044802 93 0.013
response to hexose GO:0009746 3 0.013
single organism cellular localization GO:1902580 180 0.013
programmed cell death GO:0012501 257 0.012
retina development in camera type eye GO:0060041 4 0.012
regulation of cell projection organization GO:0031344 92 0.012
acylglycerol metabolic process GO:0006639 12 0.012
g protein coupled receptor signaling pathway GO:0007186 136 0.012
regulation of cell substrate adhesion GO:0010810 2 0.012
intracellular transport GO:0046907 228 0.012
respiratory system development GO:0060541 213 0.012
positive regulation of transcription dna templated GO:0045893 266 0.012
cell projection assembly GO:0030031 94 0.012
dna integrity checkpoint GO:0031570 81 0.012
regulation of gene silencing GO:0060968 63 0.012
response to monosaccharide GO:0034284 4 0.012
regulation of cellular component movement GO:0051270 42 0.012
positive regulation of transport GO:0051050 92 0.012
organonitrogen compound catabolic process GO:1901565 128 0.012
positive regulation of rna metabolic process GO:0051254 271 0.012
signal transduction by phosphorylation GO:0023014 107 0.012
response to pain GO:0048265 3 0.012
cell cycle checkpoint GO:0000075 95 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
positive regulation of growth GO:0045927 75 0.012
mesenchymal cell development GO:0014031 1 0.012
mesenchymal cell differentiation GO:0048762 1 0.012
nucleotide metabolic process GO:0009117 161 0.012
neurotransmitter metabolic process GO:0042133 2 0.012
spermatid development GO:0007286 98 0.012
regulation of cell differentiation GO:0045595 302 0.012
response to inorganic substance GO:0010035 44 0.012
cellular nitrogen compound catabolic process GO:0044270 165 0.012
leg disc morphogenesis GO:0007478 80 0.012
mating GO:0007618 120 0.012
detection of stimulus involved in sensory perception GO:0050906 92 0.012
purine nucleoside metabolic process GO:0042278 127 0.012
modification dependent protein catabolic process GO:0019941 78 0.012
determination of adult lifespan GO:0008340 137 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
transmembrane transport GO:0055085 139 0.012
response to metal ion GO:0010038 23 0.012
regulation of catabolic process GO:0009894 170 0.012
immune system process GO:0002376 347 0.012
motor neuron axon guidance GO:0008045 58 0.011
dna damage checkpoint GO:0000077 78 0.011
insecticide catabolic process GO:0046701 1 0.011
axis specification GO:0009798 167 0.011
humoral immune response GO:0006959 117 0.011
imaginal disc derived leg morphogenesis GO:0007480 80 0.011
toxin catabolic process GO:0009407 1 0.011
regulation of synapse assembly GO:0051963 94 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
response to glucose GO:0009749 2 0.011
tube morphogenesis GO:0035239 191 0.011
anatomical structure homeostasis GO:0060249 97 0.011
response to radiation GO:0009314 155 0.011
nitrogen compound transport GO:0071705 85 0.011
phosphatidylcholine metabolic process GO:0046470 3 0.011
regulation of cholesterol transport GO:0032374 1 0.011
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.011
regulation of mitotic cell cycle phase transition GO:1901990 130 0.011
wound healing GO:0042060 75 0.011
epithelial cell migration GO:0010631 148 0.011
cell junction assembly GO:0034329 42 0.011
digestive system development GO:0055123 149 0.011
gene silencing by rna GO:0031047 57 0.011
ion transport GO:0006811 145 0.011
regulation of synapse structure and activity GO:0050803 128 0.011
purine containing compound catabolic process GO:0072523 112 0.011
regulation of response to external stimulus GO:0032101 115 0.011
regulation of programmed cell death GO:0043067 152 0.011
positive regulation of mapk cascade GO:0043410 63 0.011
regulation of epithelial cell proliferation GO:0050678 4 0.011
cellular homeostasis GO:0019725 80 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
regulation of organelle organization GO:0033043 196 0.011
microtubule organizing center organization GO:0031023 168 0.011
connective tissue development GO:0061448 3 0.011
ribose phosphate metabolic process GO:0019693 145 0.011
estrogen metabolic process GO:0008210 1 0.011
regulation of protein metabolic process GO:0051246 256 0.011
cell junction organization GO:0034330 57 0.011
negative regulation of cell cycle phase transition GO:1901988 103 0.011
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.010
purine nucleoside triphosphate catabolic process GO:0009146 108 0.010
mating behavior GO:0007617 106 0.010
enzyme linked receptor protein signaling pathway GO:0007167 179 0.010
regulation of mrna processing GO:0050684 71 0.010
positive regulation of nucleic acid templated transcription GO:1903508 266 0.010
cell adhesion GO:0007155 136 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
response to mercury ion GO:0046689 3 0.010
response to ethanol GO:0045471 59 0.010
positive regulation of jun kinase activity GO:0043507 4 0.010
detection of external biotic stimulus GO:0098581 2 0.010
morphogenesis of an epithelium GO:0002009 276 0.010
columnar cuboidal epithelial cell development GO:0002066 249 0.010
response to extracellular stimulus GO:0009991 116 0.010
purine nucleoside triphosphate metabolic process GO:0009144 119 0.010
cellular response to endogenous stimulus GO:0071495 80 0.010
positive regulation of rna biosynthetic process GO:1902680 266 0.010
acid secretion GO:0046717 1 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
actin filament organization GO:0007015 126 0.010
long chain fatty acid metabolic process GO:0001676 3 0.010
response to alcohol GO:0097305 95 0.010
regulation of rna splicing GO:0043484 69 0.010
mitotic cell cycle phase transition GO:0044772 138 0.010
positive regulation of cell death GO:0010942 69 0.010
cellular response to biotic stimulus GO:0071216 4 0.010
cell fate determination GO:0001709 91 0.010
cell division GO:0051301 248 0.010
cell recognition GO:0008037 102 0.010

CG8449 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.126
disease of metabolism DOID:0014667 0 0.039
cardiovascular system disease DOID:1287 0 0.033
nervous system disease DOID:863 0 0.031
inherited metabolic disorder DOID:655 0 0.029
acquired metabolic disease DOID:0060158 0 0.026
diabetes mellitus DOID:9351 0 0.020
type 2 diabetes mellitus DOID:9352 0 0.020
carbohydrate metabolism disease DOID:0050013 0 0.020
glucose metabolism disease DOID:4194 0 0.020
artery disease DOID:0050828 0 0.019
vascular disease DOID:178 0 0.019
hypertension DOID:10763 0 0.017
familial hyperlipidemia DOID:1168 0 0.016
lipid metabolism disorder DOID:3146 0 0.016
familial combined hyperlipidemia DOID:13809 0 0.016
familial lipoprotein lipase deficiency DOID:14118 0 0.016
central nervous system disease DOID:331 0 0.015
hair disease DOID:421 0 0.012
integumentary system disease DOID:16 0 0.012
sensory system disease DOID:0050155 0 0.012
musculoskeletal system disease DOID:17 0 0.012
cancer DOID:162 0 0.011
disease of cellular proliferation DOID:14566 0 0.011
organ system cancer DOID:0050686 0 0.011
eye and adnexa disease DOID:1492 0 0.011
eye disease DOID:5614 0 0.011
hypotrichosis DOID:4535 0 0.011
kidney disease DOID:557 0 0.010
urinary system disease DOID:18 0 0.010