Drosophila melanogaster

30 known processes

nAcRalpha-30D (Dmel_CG4128)

nicotinic Acetylcholine Receptor alpha 30D

(Aliases: Dalpha6,rsn,alpha6,CG4128,Dmel\CG4128,CT13662,nAChR alpha 6,BcDNA:GH01410,nAChR)

nAcRalpha-30D biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
cation transmembrane transport GO:0098655 88 0.577
synaptic transmission GO:0007268 288 0.464
ion transmembrane transport GO:0034220 122 0.402
single organism behavior GO:0044708 391 0.378
response to insecticide GO:0017085 14 0.370
transmembrane transport GO:0055085 139 0.327
cation transport GO:0006812 110 0.254
adult behavior GO:0030534 137 0.245
vesicle mediated transport GO:0016192 381 0.213
regulation of synaptic transmission GO:0050804 69 0.188
sleep GO:0030431 49 0.170
response to abiotic stimulus GO:0009628 341 0.150
regulation of membrane potential GO:0042391 35 0.139
taxis GO:0042330 304 0.123
metal ion transport GO:0030001 74 0.116
negative regulation of purine nucleotide biosynthetic process GO:1900372 3 0.111
ion transport GO:0006811 145 0.101
regulation of excitatory postsynaptic membrane potential GO:0060079 3 0.090
locomotory behavior GO:0007626 176 0.089
adult locomotory behavior GO:0008344 76 0.086
response to toxic substance GO:0009636 22 0.083
regulation of localization GO:0032879 275 0.075
regulation of cell proliferation GO:0042127 163 0.074
response to organic substance GO:0010033 284 0.073
regulation of secretion by cell GO:1903530 39 0.072
carbohydrate derivative biosynthetic process GO:1901137 85 0.061
regulation of cellular localization GO:0060341 136 0.059
regulation of transport GO:0051049 181 0.059
ribonucleotide metabolic process GO:0009259 145 0.058
secretion GO:0046903 109 0.052
insecticide catabolic process GO:0046701 1 0.052
regulation of behavior GO:0050795 75 0.051
nucleoside phosphate metabolic process GO:0006753 162 0.049
purine ribonucleotide metabolic process GO:0009150 145 0.048
purine nucleotide metabolic process GO:0006163 146 0.047
inorganic cation transmembrane transport GO:0098662 61 0.047
membrane depolarization GO:0051899 4 0.045
embryonic organ development GO:0048568 50 0.044
positive regulation of exocytosis GO:0045921 4 0.043
regulation of phosphate metabolic process GO:0019220 210 0.043
neuropeptide signaling pathway GO:0007218 45 0.040
tube development GO:0035295 244 0.040
regulation of neurotransmitter secretion GO:0046928 14 0.039
medium chain fatty acid metabolic process GO:0051791 1 0.039
organophosphate metabolic process GO:0019637 195 0.038
positive regulation of cgmp metabolic process GO:0030825 1 0.037
regulation of lyase activity GO:0051339 14 0.037
exocytosis GO:0006887 28 0.037
synaptic transmission cholinergic GO:0007271 9 0.037
negative regulation of signaling GO:0023057 219 0.037
regulation of nucleotide metabolic process GO:0006140 62 0.036
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.036
signal release GO:0023061 49 0.036
carbohydrate derivative metabolic process GO:1901135 217 0.036
neuroblast proliferation GO:0007405 74 0.035
regulation of secretion GO:0051046 44 0.035
monovalent inorganic cation transport GO:0015672 40 0.035
nucleobase containing small molecule metabolic process GO:0055086 174 0.035
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.034
divalent metal ion transport GO:0070838 26 0.034
small molecule metabolic process GO:0044281 305 0.034
regulation of molecular function GO:0065009 217 0.033
learning GO:0007612 75 0.033
purine nucleotide biosynthetic process GO:0006164 29 0.032
response to temperature stimulus GO:0009266 106 0.032
chemotaxis GO:0006935 249 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
behavioral response to ethanol GO:0048149 49 0.032
regulation of vesicle mediated transport GO:0060627 59 0.031
sensory organ morphogenesis GO:0090596 260 0.031
positive regulation of nucleic acid templated transcription GO:1903508 266 0.031
olfactory learning GO:0008355 56 0.031
ribose phosphate metabolic process GO:0019693 145 0.031
tissue morphogenesis GO:0048729 297 0.031
secretion by cell GO:0032940 101 0.031
negative regulation of camp metabolic process GO:0030815 3 0.031
biological adhesion GO:0022610 138 0.031
camp biosynthetic process GO:0006171 17 0.031
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.030
golgi organization GO:0007030 66 0.029
cellular response to ethanol GO:0071361 4 0.029
neuronal stem cell division GO:0036445 35 0.029
neurotransmitter secretion GO:0007269 35 0.029
potassium ion transport GO:0006813 20 0.029
macromolecular complex assembly GO:0065003 256 0.028
response to light stimulus GO:0009416 124 0.028
regulation of cellular amino acid metabolic process GO:0006521 0 0.028
cell proliferation GO:0008283 299 0.027
cellular nitrogen compound catabolic process GO:0044270 165 0.027
organonitrogen compound biosynthetic process GO:1901566 117 0.027
regulation of cyclic nucleotide metabolic process GO:0030799 13 0.027
malpighian tubule development GO:0072002 64 0.027
response to ethanol GO:0045471 59 0.027
renal system process GO:0003014 12 0.027
inositol lipid mediated signaling GO:0048017 4 0.027
endocytosis GO:0006897 310 0.026
establishment of localization in cell GO:0051649 402 0.026
regulation of anatomical structure size GO:0090066 163 0.026
rhythmic behavior GO:0007622 76 0.026
response to organophosphorus GO:0046683 2 0.026
phosphatidylinositol mediated signaling GO:0048015 4 0.026
nucleotide metabolic process GO:0009117 161 0.025
olfactory behavior GO:0042048 97 0.025
catabolic process GO:0009056 409 0.025
purine nucleoside catabolic process GO:0006152 112 0.025
cellular homeostasis GO:0019725 80 0.024
actin filament based process GO:0030029 220 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.024
phagocytosis GO:0006909 215 0.024
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.024
ribonucleoside metabolic process GO:0009119 127 0.023
inorganic ion transmembrane transport GO:0098660 73 0.023
multi organism behavior GO:0051705 175 0.023
positive regulation of phosphate metabolic process GO:0045937 139 0.023
embryonic morphogenesis GO:0048598 206 0.023
lauric acid metabolic process GO:0048252 1 0.023
heart process GO:0003015 37 0.023
nucleoside metabolic process GO:0009116 127 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
g protein coupled receptor signaling pathway GO:0007186 136 0.023
positive regulation of phosphorus metabolic process GO:0010562 139 0.023
regionalization GO:0003002 416 0.022
organic cyclic compound catabolic process GO:1901361 168 0.022
purine ribonucleoside metabolic process GO:0046128 127 0.022
axon development GO:0061564 297 0.022
response to radiation GO:0009314 155 0.022
actin filament organization GO:0007015 126 0.022
positive regulation of signaling GO:0023056 243 0.022
endomembrane system organization GO:0010256 119 0.022
positive regulation of phosphorylation GO:0042327 87 0.021
organonitrogen compound catabolic process GO:1901565 128 0.021
sensory perception GO:0007600 196 0.021
response to heat GO:0009408 63 0.021
cellular catabolic process GO:0044248 372 0.021
purine containing compound metabolic process GO:0072521 155 0.021
regulation of cellular component biogenesis GO:0044087 201 0.021
single organism catabolic process GO:0044712 228 0.020
nucleoside phosphate biosynthetic process GO:1901293 34 0.020
positive regulation of biosynthetic process GO:0009891 316 0.020
connective tissue development GO:0061448 3 0.020
camera type eye development GO:0043010 4 0.020
cellular response to chemical stimulus GO:0070887 199 0.020
purine containing compound catabolic process GO:0072523 112 0.020
organophosphate biosynthetic process GO:0090407 46 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
positive regulation of nucleotide metabolic process GO:0045981 55 0.019
cellular response to organic substance GO:0071310 132 0.019
cellular protein modification process GO:0006464 438 0.019
cell maturation GO:0048469 144 0.019
cognition GO:0050890 141 0.019
tube morphogenesis GO:0035239 191 0.019
organic substance catabolic process GO:1901575 308 0.019
chemical homeostasis GO:0048878 92 0.019
neuroblast division GO:0055057 35 0.018
enzyme linked receptor protein signaling pathway GO:0007167 179 0.018
regulation of cell differentiation GO:0045595 302 0.018
purine ribonucleotide catabolic process GO:0009154 109 0.018
regulation of catalytic activity GO:0050790 185 0.018
regulation of immune system process GO:0002682 176 0.018
response to alcohol GO:0097305 95 0.017
single organism membrane organization GO:0044802 93 0.017
negative regulation of camp biosynthetic process GO:0030818 3 0.017
calcium ion transport GO:0006816 24 0.017
regulation of ion transport GO:0043269 39 0.017
regulation of cell substrate adhesion GO:0010810 2 0.017
ribose phosphate biosynthetic process GO:0046390 28 0.017
hematopoietic progenitor cell differentiation GO:0002244 1 0.017
single organism cell adhesion GO:0098602 47 0.017
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.017
transcription from rna polymerase ii promoter GO:0006366 368 0.017
ribonucleotide biosynthetic process GO:0009260 28 0.017
protein modification process GO:0036211 438 0.017
neuromuscular synaptic transmission GO:0007274 67 0.017
negative regulation of biosynthetic process GO:0009890 277 0.017
lateral inhibition GO:0046331 206 0.016
urogenital system development GO:0001655 72 0.016
purine nucleotide catabolic process GO:0006195 109 0.016
oocyte anterior posterior axis specification GO:0007314 72 0.016
embryonic development via the syncytial blastoderm GO:0001700 148 0.016
aromatic compound catabolic process GO:0019439 166 0.016
purine nucleoside metabolic process GO:0042278 127 0.016
compound eye development GO:0048749 307 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
response to lipopolysaccharide GO:0032496 4 0.016
organic acid metabolic process GO:0006082 103 0.016
morphogenesis of an epithelium GO:0002009 276 0.016
aggressive behavior GO:0002118 63 0.016
cell cell junction organization GO:0045216 55 0.016
motor neuron axon guidance GO:0008045 58 0.016
cellular cation homeostasis GO:0030003 38 0.016
retina development in camera type eye GO:0060041 4 0.016
regulation of purine nucleotide metabolic process GO:1900542 62 0.016
blood circulation GO:0008015 26 0.016
negative regulation of homeostatic process GO:0032845 2 0.016
ribonucleotide catabolic process GO:0009261 109 0.015
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
regulation of neurotransmitter levels GO:0001505 38 0.015
regulation of system process GO:0044057 36 0.015
positive regulation of organelle organization GO:0010638 65 0.015
positive regulation of immune system process GO:0002684 68 0.015
positive regulation of cell motility GO:2000147 3 0.015
asymmetric stem cell division GO:0098722 49 0.015
negative regulation of cell communication GO:0010648 223 0.015
anatomical structure homeostasis GO:0060249 97 0.015
glycosyl compound catabolic process GO:1901658 112 0.015
homeostatic process GO:0042592 199 0.015
eye development GO:0001654 323 0.015
ras protein signal transduction GO:0007265 88 0.015
detection of external stimulus GO:0009581 66 0.015
digestive tract development GO:0048565 149 0.015
growth GO:0040007 359 0.015
regulation of circadian sleep wake cycle GO:0042749 25 0.015
heterocycle catabolic process GO:0046700 166 0.015
cell death GO:0008219 279 0.015
ribonucleoside triphosphate metabolic process GO:0009199 119 0.014
regulation of cell projection organization GO:0031344 92 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
cellular divalent inorganic cation homeostasis GO:0072503 23 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
stem cell proliferation GO:0072089 88 0.014
regulation of developmental growth GO:0048638 174 0.014
oxoacid metabolic process GO:0043436 103 0.014
protein complex biogenesis GO:0070271 201 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
purine ribonucleoside catabolic process GO:0046130 112 0.014
fat soluble vitamin biosynthetic process GO:0042362 1 0.014
positive regulation of cell migration GO:0030335 2 0.014
regulation of cell development GO:0060284 215 0.014
regulation of cellular component size GO:0032535 98 0.014
purine ribonucleotide biosynthetic process GO:0009152 28 0.014
programmed cell death GO:0012501 257 0.014
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.014
action potential GO:0001508 13 0.014
regulation of cellular catabolic process GO:0031329 157 0.014
response to oxygen containing compound GO:1901700 200 0.014
negative regulation of synaptic transmission GO:0050805 12 0.013
phosphorylation GO:0016310 294 0.013
intracellular signal transduction GO:0035556 300 0.013
mapk cascade GO:0000165 107 0.013
regulation of olfactory learning GO:0090328 8 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
regulation of epithelial cell proliferation GO:0050678 4 0.013
eggshell formation GO:0030703 105 0.013
cell growth GO:0016049 108 0.013
apoptotic process GO:0006915 159 0.013
vitamin metabolic process GO:0006766 2 0.013
synaptic vesicle transport GO:0048489 50 0.013
glycosyl compound metabolic process GO:1901657 127 0.013
regulation of organelle organization GO:0033043 196 0.013
death GO:0016265 284 0.013
forebrain development GO:0030900 2 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
vitamin biosynthetic process GO:0009110 1 0.013
axis specification GO:0009798 167 0.013
acetate ester metabolic process GO:1900619 2 0.013
inorganic anion transmembrane transport GO:0098661 14 0.013
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.013
negative regulation of signal transduction GO:0009968 206 0.012
nucleoside phosphate catabolic process GO:1901292 110 0.012
divalent inorganic cation transport GO:0072511 30 0.012
positive regulation of cell communication GO:0010647 250 0.012
circulatory system process GO:0003013 37 0.012
steroid catabolic process GO:0006706 1 0.012
positive regulation of cellular protein metabolic process GO:0032270 118 0.012
larval behavior GO:0030537 42 0.012
cellular response to carbohydrate stimulus GO:0071322 4 0.012
ribonucleoside triphosphate catabolic process GO:0009203 108 0.012
cyclic nucleotide biosynthetic process GO:0009190 25 0.012
regulation of cellular amine metabolic process GO:0033238 3 0.012
circadian behavior GO:0048512 76 0.012
adherens junction organization GO:0034332 27 0.012
cellular response to hexose stimulus GO:0071331 1 0.012
single organism biosynthetic process GO:0044711 206 0.012
carbohydrate metabolic process GO:0005975 82 0.012
response to biotic stimulus GO:0009607 294 0.012
regulation of purine nucleotide biosynthetic process GO:1900371 14 0.012
heterophilic cell cell adhesion via plasma membrane cell adhesion molecules GO:0007157 8 0.012
body morphogenesis GO:0010171 2 0.012
aging GO:0007568 143 0.012
appendage development GO:0048736 401 0.012
positive regulation of cellular catabolic process GO:0031331 95 0.012
response to extracellular stimulus GO:0009991 116 0.011
immune response activating signal transduction GO:0002757 2 0.011
response to hypoxia GO:0001666 53 0.011
regulation of neural precursor cell proliferation GO:2000177 35 0.011
cardiovascular system development GO:0072358 82 0.011
developmental maturation GO:0021700 172 0.011
positive regulation of rna metabolic process GO:0051254 271 0.011
regulation of nucleotide biosynthetic process GO:0030808 14 0.011
larval development GO:0002164 104 0.011
kidney development GO:0001822 3 0.011
limb development GO:0060173 1 0.011
positive regulation of cellular component biogenesis GO:0044089 80 0.011
camera type eye morphogenesis GO:0048593 2 0.011
response to monosaccharide GO:0034284 4 0.011
cardiocyte differentiation GO:0035051 29 0.011
protein heterooligomerization GO:0051291 4 0.011
cellular ion homeostasis GO:0006873 39 0.011
organelle assembly GO:0070925 198 0.011
regulation of multicellular organismal development GO:2000026 414 0.011
female sex differentiation GO:0046660 20 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
cellular amino acid metabolic process GO:0006520 61 0.011
regulation of neuromuscular synaptic transmission GO:1900073 15 0.011
regulation of purine nucleotide catabolic process GO:0033121 48 0.011
negative regulation of response to stimulus GO:0048585 258 0.011
cellular ketone metabolic process GO:0042180 24 0.011
chromosome organization GO:0051276 360 0.011
segmentation GO:0035282 207 0.011
single organism carbohydrate metabolic process GO:0044723 72 0.011
chromatin modification GO:0016568 147 0.011
cellular amine metabolic process GO:0044106 12 0.011
regulation of metal ion transport GO:0010959 15 0.011
divalent inorganic cation homeostasis GO:0072507 29 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
organic substance transport GO:0071702 257 0.011
response to endogenous stimulus GO:0009719 119 0.010
nucleoside catabolic process GO:0009164 112 0.010
positive regulation of i kappab kinase nf kappab signaling GO:0043123 1 0.010
spinal cord development GO:0021510 1 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
circulatory system development GO:0072359 82 0.010
carbohydrate derivative catabolic process GO:1901136 118 0.010
regulation of cyclase activity GO:0031279 13 0.010
embryo development ending in birth or egg hatching GO:0009792 152 0.010
positive regulation of molecular function GO:0044093 136 0.010
cellular response to mechanical stimulus GO:0071260 2 0.010
regulation of mapk cascade GO:0043408 92 0.010
response to external biotic stimulus GO:0043207 293 0.010
cgmp biosynthetic process GO:0006182 8 0.010
single organism membrane fusion GO:0044801 42 0.010
pole plasm rna localization GO:0007316 52 0.010
negative regulation of erbb signaling pathway GO:1901185 29 0.010

nAcRalpha-30D disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.033
musculoskeletal system disease DOID:17 0 0.030
cardiovascular system disease DOID:1287 0 0.030
artery disease DOID:0050828 0 0.021
vascular disease DOID:178 0 0.021
hypertension DOID:10763 0 0.017
cancer DOID:162 0 0.013
disease of cellular proliferation DOID:14566 0 0.013
nervous system disease DOID:863 0 0.013