|
proteasome assembly
|
GO:0043248 |
2 |
0.452
|
|
|
protein modification by small protein conjugation or removal
|
GO:0070647 |
106 |
0.438
|
|
|
cellular catabolic process
|
GO:0044248 |
372 |
0.399
|
Human Yeast |
|
positive regulation of proteolysis
|
GO:0045862 |
52 |
0.397
|
|
|
proteolysis
|
GO:0006508 |
192 |
0.380
|
Human Yeast |
|
protein dna complex assembly
|
GO:0065004 |
63 |
0.367
|
|
|
determination of adult lifespan
|
GO:0008340 |
137 |
0.298
|
|
|
positive regulation of endopeptidase activity
|
GO:0010950 |
26 |
0.255
|
|
|
modification dependent macromolecule catabolic process
|
GO:0043632 |
79 |
0.235
|
|
|
cellular protein modification process
|
GO:0006464 |
438 |
0.230
|
|
|
multicellular organismal aging
|
GO:0010259 |
140 |
0.190
|
|
|
aging
|
GO:0007568 |
143 |
0.180
|
|
|
positive regulation of peptidase activity
|
GO:0010952 |
29 |
0.174
|
|
|
regulation of cellular protein metabolic process
|
GO:0032268 |
243 |
0.150
|
Human Yeast |
|
dna templated transcription elongation
|
GO:0006354 |
18 |
0.149
|
|
|
positive regulation of proteolysis involved in cellular protein catabolic process
|
GO:1903052 |
24 |
0.147
|
|
|
positive regulation of nucleic acid templated transcription
|
GO:1903508 |
266 |
0.147
|
|
|
regulation of transcription from rna polymerase ii promoter
|
GO:0006357 |
378 |
0.144
|
|
|
larval development
|
GO:0002164 |
104 |
0.121
|
|
|
positive regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043280 |
23 |
0.117
|
|
|
cellular macromolecular complex assembly
|
GO:0034622 |
153 |
0.116
|
|
|
positive regulation of macromolecule metabolic process
|
GO:0010604 |
405 |
0.115
|
|
|
macromolecule catabolic process
|
GO:0009057 |
161 |
0.115
|
Human Yeast |
|
protein modification process
|
GO:0036211 |
438 |
0.110
|
|
|
ubiquitin dependent protein catabolic process
|
GO:0006511 |
78 |
0.107
|
|
|
macromolecular complex assembly
|
GO:0065003 |
256 |
0.105
|
|
|
modification dependent protein catabolic process
|
GO:0019941 |
78 |
0.101
|
|
|
protein complex biogenesis
|
GO:0070271 |
201 |
0.099
|
|
|
regulation of dna templated transcription elongation
|
GO:0032784 |
17 |
0.099
|
|
|
positive regulation of transcription from rna polymerase ii promoter
|
GO:0045944 |
204 |
0.094
|
|
|
apoptotic process
|
GO:0006915 |
159 |
0.092
|
|
|
positive regulation of nucleobase containing compound metabolic process
|
GO:0045935 |
332 |
0.089
|
|
|
catabolic process
|
GO:0009056 |
409 |
0.089
|
Human Yeast |
|
regulation of proteolysis
|
GO:0030162 |
87 |
0.087
|
Human Yeast |
|
death
|
GO:0016265 |
284 |
0.087
|
|
|
cellular macromolecule catabolic process
|
GO:0044265 |
136 |
0.086
|
Human Yeast |
|
purine ribonucleoside monophosphate metabolic process
|
GO:0009167 |
50 |
0.084
|
|
|
embryo development ending in birth or egg hatching
|
GO:0009792 |
152 |
0.083
|
|
|
transcription initiation from rna polymerase ii promoter
|
GO:0006367 |
25 |
0.083
|
|
|
regulation of endopeptidase activity
|
GO:0052548 |
36 |
0.082
|
Human |
|
cellular response to dna damage stimulus
|
GO:0006974 |
223 |
0.078
|
|
|
transcription from rna polymerase ii promoter
|
GO:0006366 |
368 |
0.078
|
|
|
proteolysis involved in cellular protein catabolic process
|
GO:0051603 |
83 |
0.078
|
Human Yeast |
|
positive regulation of cysteine type endopeptidase activity
|
GO:2001056 |
24 |
0.075
|
|
|
cellular protein catabolic process
|
GO:0044257 |
83 |
0.074
|
Human Yeast |
|
organic substance catabolic process
|
GO:1901575 |
308 |
0.071
|
Human Yeast |
|
regulation of peptidase activity
|
GO:0052547 |
39 |
0.067
|
Human |
|
protein complex assembly
|
GO:0006461 |
200 |
0.065
|
|
|
activation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0006919 |
16 |
0.064
|
|
|
dna repair
|
GO:0006281 |
54 |
0.062
|
|
|
proteasome mediated ubiquitin dependent protein catabolic process
|
GO:0043161 |
54 |
0.062
|
|
|
protein ubiquitination
|
GO:0016567 |
70 |
0.061
|
|
|
protein modification by small protein removal
|
GO:0070646 |
28 |
0.058
|
Human Yeast |
|
double strand break repair via nonhomologous end joining
|
GO:0006303 |
5 |
0.058
|
|
|
nuclear division
|
GO:0000280 |
332 |
0.056
|
|
|
proteasomal protein catabolic process
|
GO:0010498 |
59 |
0.056
|
Human Yeast |
|
protein catabolic process
|
GO:0030163 |
101 |
0.055
|
Human Yeast |
|
regulation of golgi to plasma membrane protein transport
|
GO:0042996 |
6 |
0.055
|
|
|
positive regulation of cellular biosynthetic process
|
GO:0031328 |
316 |
0.053
|
|
|
positive regulation of rna biosynthetic process
|
GO:1902680 |
266 |
0.051
|
|
|
regulation of i kappab kinase nf kappab signaling
|
GO:0043122 |
2 |
0.051
|
|
|
positive regulation of gene expression
|
GO:0010628 |
290 |
0.051
|
|
|
dna metabolic process
|
GO:0006259 |
227 |
0.051
|
|
|
positive regulation of cellular protein metabolic process
|
GO:0032270 |
118 |
0.051
|
|
|
nucleoside triphosphate metabolic process
|
GO:0009141 |
120 |
0.050
|
|
|
cell death
|
GO:0008219 |
279 |
0.050
|
|
|
immune system process
|
GO:0002376 |
347 |
0.049
|
|
|
regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032434 |
37 |
0.049
|
|
|
organelle fission
|
GO:0048285 |
340 |
0.049
|
|
|
organic substance transport
|
GO:0071702 |
257 |
0.048
|
|
|
cell motility
|
GO:0048870 |
251 |
0.046
|
|
|
positive regulation of proteasomal protein catabolic process
|
GO:1901800 |
20 |
0.046
|
|
|
cullin deneddylation
|
GO:0010388 |
3 |
0.042
|
|
|
regulation of cellular catabolic process
|
GO:0031329 |
157 |
0.042
|
Human Yeast |
|
ribonucleoside triphosphate metabolic process
|
GO:0009199 |
119 |
0.042
|
|
|
male gamete generation
|
GO:0048232 |
201 |
0.042
|
|
|
regulation of mitosis
|
GO:0007088 |
56 |
0.039
|
|
|
positive regulation of protein metabolic process
|
GO:0051247 |
128 |
0.038
|
|
|
er associated ubiquitin dependent protein catabolic process
|
GO:0030433 |
3 |
0.038
|
|
|
camera type eye development
|
GO:0043010 |
4 |
0.038
|
|
|
regulation of meiosis
|
GO:0040020 |
3 |
0.037
|
|
|
response to other organism
|
GO:0051707 |
293 |
0.037
|
|
|
protein modification by small protein conjugation
|
GO:0032446 |
79 |
0.037
|
|
|
nucleoside metabolic process
|
GO:0009116 |
127 |
0.037
|
|
|
protein transport
|
GO:0015031 |
155 |
0.036
|
|
|
response to biotic stimulus
|
GO:0009607 |
294 |
0.035
|
|
|
response to external biotic stimulus
|
GO:0043207 |
293 |
0.035
|
|
|
protein deubiquitination
|
GO:0016579 |
17 |
0.035
|
Human Yeast |
|
single organism cellular localization
|
GO:1902580 |
180 |
0.031
|
|
|
positive regulation of nitrogen compound metabolic process
|
GO:0051173 |
354 |
0.031
|
|
|
establishment of protein localization
|
GO:0045184 |
163 |
0.031
|
|
|
programmed cell death
|
GO:0012501 |
257 |
0.030
|
|
|
positive regulation of proteasomal ubiquitin dependent protein catabolic process
|
GO:0032436 |
19 |
0.030
|
|
|
cellular protein complex assembly
|
GO:0043623 |
71 |
0.029
|
|
|
protein deneddylation
|
GO:0000338 |
8 |
0.029
|
|
|
regulation of cell division
|
GO:0051302 |
72 |
0.029
|
|
|
intracellular transport
|
GO:0046907 |
228 |
0.029
|
|
|
atp metabolic process
|
GO:0046034 |
49 |
0.029
|
|
|
positive regulation of transcription dna templated
|
GO:0045893 |
266 |
0.029
|
|
|
ribonucleoside catabolic process
|
GO:0042454 |
112 |
0.028
|
|
|
cell migration
|
GO:0016477 |
238 |
0.028
|
|
|
mitotic nuclear division
|
GO:0007067 |
213 |
0.028
|
|
|
positive regulation of macromolecule biosynthetic process
|
GO:0010557 |
283 |
0.028
|
|
|
positive regulation of biosynthetic process
|
GO:0009891 |
316 |
0.028
|
|
|
positive regulation of cell death
|
GO:0010942 |
69 |
0.028
|
|
|
regulation of intracellular protein transport
|
GO:0033157 |
46 |
0.028
|
|
|
aromatic compound catabolic process
|
GO:0019439 |
166 |
0.028
|
|
|
reproductive structure development
|
GO:0048608 |
74 |
0.027
|
|
|
glycosyl compound catabolic process
|
GO:1901658 |
112 |
0.027
|
|
|
nucleobase containing small molecule metabolic process
|
GO:0055086 |
174 |
0.027
|
|
|
ribonucleoside metabolic process
|
GO:0009119 |
127 |
0.026
|
|
|
organic cyclic compound catabolic process
|
GO:1901361 |
168 |
0.025
|
|
|
nucleoside phosphate metabolic process
|
GO:0006753 |
162 |
0.025
|
|
|
ribonucleoside monophosphate catabolic process
|
GO:0009158 |
39 |
0.025
|
|
|
humoral immune response
|
GO:0006959 |
117 |
0.025
|
|
|
spermatogenesis
|
GO:0007283 |
200 |
0.024
|
|
|
regulation of cell cycle process
|
GO:0010564 |
181 |
0.024
|
|
|
eye morphogenesis
|
GO:0048592 |
260 |
0.024
|
|
|
purine ribonucleoside metabolic process
|
GO:0046128 |
127 |
0.024
|
|
|
cellular nitrogen compound catabolic process
|
GO:0044270 |
165 |
0.024
|
|
|
ribose phosphate metabolic process
|
GO:0019693 |
145 |
0.024
|
|
|
regulation of cell cycle
|
GO:0051726 |
291 |
0.024
|
|
|
organonitrogen compound catabolic process
|
GO:1901565 |
128 |
0.023
|
|
|
regulation of protein metabolic process
|
GO:0051246 |
256 |
0.023
|
Human Yeast |
|
vesicle mediated transport
|
GO:0016192 |
381 |
0.023
|
|
|
positive regulation of protein catabolic process
|
GO:0045732 |
34 |
0.023
|
|
|
regulation of localization
|
GO:0032879 |
275 |
0.023
|
|
|
purine ribonucleoside triphosphate catabolic process
|
GO:0009207 |
108 |
0.022
|
|
|
immune response
|
GO:0006955 |
246 |
0.021
|
|
|
regulation of organelle organization
|
GO:0033043 |
196 |
0.021
|
|
|
ribonucleotide metabolic process
|
GO:0009259 |
145 |
0.021
|
|
|
mitotic spindle organization
|
GO:0007052 |
220 |
0.021
|
|
|
regulation of mitotic cell cycle
|
GO:0007346 |
190 |
0.021
|
|
|
purine containing compound catabolic process
|
GO:0072523 |
112 |
0.021
|
|
|
organophosphate metabolic process
|
GO:0019637 |
195 |
0.021
|
|
|
single organism intracellular transport
|
GO:1902582 |
207 |
0.021
|
|
|
regulation of intracellular transport
|
GO:0032386 |
64 |
0.021
|
|
|
transcription elongation from rna polymerase ii promoter
|
GO:0006368 |
18 |
0.020
|
|
|
endocytosis
|
GO:0006897 |
310 |
0.020
|
|
|
cell division
|
GO:0051301 |
248 |
0.020
|
|
|
regulation of programmed cell death
|
GO:0043067 |
152 |
0.020
|
|
|
purine nucleoside monophosphate metabolic process
|
GO:0009126 |
50 |
0.019
|
|
|
transmembrane transport
|
GO:0055085 |
139 |
0.019
|
|
|
purine nucleoside triphosphate catabolic process
|
GO:0009146 |
108 |
0.019
|
|
|
purine ribonucleotide metabolic process
|
GO:0009150 |
145 |
0.019
|
|
|
ribonucleoside monophosphate metabolic process
|
GO:0009161 |
51 |
0.018
|
|
|
posttranscriptional regulation of gene expression
|
GO:0010608 |
145 |
0.018
|
|
|
nucleotide excision repair
|
GO:0006289 |
8 |
0.018
|
|
|
purine nucleoside triphosphate metabolic process
|
GO:0009144 |
119 |
0.018
|
|
|
antimicrobial humoral response
|
GO:0019730 |
99 |
0.018
|
|
|
heterocycle catabolic process
|
GO:0046700 |
166 |
0.018
|
|
|
organonitrogen compound metabolic process
|
GO:1901564 |
318 |
0.018
|
|
|
regulation of apoptotic process
|
GO:0042981 |
130 |
0.018
|
|
|
establishment of protein localization to organelle
|
GO:0072594 |
62 |
0.018
|
|
|
regulation of defense response
|
GO:0031347 |
102 |
0.018
|
|
|
positive regulation of hydrolase activity
|
GO:0051345 |
78 |
0.018
|
|
|
negative regulation of nitrogen compound metabolic process
|
GO:0051172 |
265 |
0.018
|
|
|
purine nucleotide metabolic process
|
GO:0006163 |
146 |
0.017
|
|
|
purine containing compound metabolic process
|
GO:0072521 |
155 |
0.017
|
|
|
regulation of transport
|
GO:0051049 |
181 |
0.017
|
|
|
purine ribonucleoside triphosphate metabolic process
|
GO:0009205 |
119 |
0.017
|
|
|
regulation of cysteine type endopeptidase activity involved in apoptotic process
|
GO:0043281 |
25 |
0.017
|
|
|
response to oxygen containing compound
|
GO:1901700 |
200 |
0.017
|
|
|
gonad development
|
GO:0008406 |
50 |
0.017
|
|
|
regulation of protein localization
|
GO:0032880 |
76 |
0.017
|
|
|
nucleoside phosphate catabolic process
|
GO:1901292 |
110 |
0.017
|
|
|
nucleoside catabolic process
|
GO:0009164 |
112 |
0.017
|
|
|
cytoplasmic transport
|
GO:0016482 |
130 |
0.017
|
|
|
ribonucleotide catabolic process
|
GO:0009261 |
109 |
0.017
|
|
|
regulation of proteasomal protein catabolic process
|
GO:0061136 |
39 |
0.017
|
Human Yeast |
|
centrosome organization
|
GO:0051297 |
163 |
0.016
|
|
|
gene silencing by rna
|
GO:0031047 |
57 |
0.016
|
|
|
establishment of localization in cell
|
GO:0051649 |
402 |
0.016
|
|
|
dna templated transcription initiation
|
GO:0006352 |
25 |
0.016
|
|
|
eye development
|
GO:0001654 |
323 |
0.016
|
|
|
phagocytosis
|
GO:0006909 |
215 |
0.016
|
|
|
regulation of developmental growth
|
GO:0048638 |
174 |
0.016
|
|
|
regulation of cysteine type endopeptidase activity
|
GO:2000116 |
27 |
0.015
|
|
|
nuclear import
|
GO:0051170 |
51 |
0.015
|
|
|
small gtpase mediated signal transduction
|
GO:0007264 |
88 |
0.015
|
|
|
purine ribonucleotide catabolic process
|
GO:0009154 |
109 |
0.015
|
|
|
regulation of rna polymerase ii transcriptional preinitiation complex assembly
|
GO:0045898 |
1 |
0.015
|
|
|
development of primary sexual characteristics
|
GO:0045137 |
50 |
0.015
|
|
|
single organism biosynthetic process
|
GO:0044711 |
206 |
0.015
|
|
|
small molecule metabolic process
|
GO:0044281 |
305 |
0.015
|
|
|
microtubule organizing center organization
|
GO:0031023 |
168 |
0.015
|
|
|
reproductive system development
|
GO:0061458 |
74 |
0.015
|
|
|
nucleoside triphosphate catabolic process
|
GO:0009143 |
108 |
0.015
|
|
|
intracellular protein transport
|
GO:0006886 |
104 |
0.015
|
|
|
mitotic cell cycle phase transition
|
GO:0044772 |
138 |
0.014
|
|
|
regulation of immune system process
|
GO:0002682 |
176 |
0.014
|
|
|
positive regulation of molecular function
|
GO:0044093 |
136 |
0.014
|
|
|
nucleobase containing compound catabolic process
|
GO:0034655 |
165 |
0.014
|
|
|
regulation of response to stress
|
GO:0080134 |
200 |
0.014
|
|
|
cellular response to chemical stimulus
|
GO:0070887 |
199 |
0.014
|
|
|
epithelial cell differentiation
|
GO:0030855 |
322 |
0.014
|
|
|
regulation of hydrolase activity
|
GO:0051336 |
97 |
0.014
|
Human |
|
protein import
|
GO:0017038 |
55 |
0.014
|
|
|
negative regulation of biosynthetic process
|
GO:0009890 |
277 |
0.014
|
|
|
regulation of cell death
|
GO:0010941 |
173 |
0.014
|
|
|
regulation of transcription elongation from rna polymerase ii promoter
|
GO:0034243 |
15 |
0.013
|
|
|
nucleoside monophosphate metabolic process
|
GO:0009123 |
52 |
0.013
|
|
|
regulation of catabolic process
|
GO:0009894 |
170 |
0.013
|
Human Yeast |
|
single organism catabolic process
|
GO:0044712 |
228 |
0.013
|
|
|
carbohydrate derivative catabolic process
|
GO:1901136 |
118 |
0.013
|
|
|
ovarian nurse cell to oocyte transport
|
GO:0007300 |
27 |
0.013
|
|
|
purine ribonucleoside catabolic process
|
GO:0046130 |
112 |
0.013
|
|
|
nucleotide metabolic process
|
GO:0009117 |
161 |
0.013
|
|
|
protein targeting to nucleus
|
GO:0044744 |
51 |
0.013
|
|
|
regulation of cytoplasmic transport
|
GO:1903649 |
47 |
0.013
|
|
|
purine nucleoside monophosphate catabolic process
|
GO:0009128 |
38 |
0.013
|
|
|
regulation of establishment of protein localization
|
GO:0070201 |
61 |
0.012
|
|
|
negative regulation of mitotic cell cycle phase transition
|
GO:1901991 |
103 |
0.012
|
|
|
regulation of vesicle mediated transport
|
GO:0060627 |
59 |
0.012
|
|
|
positive regulation of cellular catabolic process
|
GO:0031331 |
95 |
0.012
|
|
|
spindle organization
|
GO:0007051 |
253 |
0.012
|
|
|
regulation of catalytic activity
|
GO:0050790 |
185 |
0.012
|
Human |
|
nucleoside monophosphate catabolic process
|
GO:0009125 |
39 |
0.012
|
|
|
gland development
|
GO:0048732 |
191 |
0.012
|
|
|
positive regulation of catalytic activity
|
GO:0043085 |
118 |
0.012
|
|
|
carbohydrate derivative metabolic process
|
GO:1901135 |
217 |
0.012
|
|
|
protein dna complex subunit organization
|
GO:0071824 |
86 |
0.012
|
|
|
regulation of molecular function
|
GO:0065009 |
217 |
0.012
|
Human |
|
dna templated transcriptional preinitiation complex assembly
|
GO:0070897 |
20 |
0.012
|
|
|
ion transport
|
GO:0006811 |
145 |
0.012
|
|
|
g2 dna damage checkpoint
|
GO:0031572 |
69 |
0.012
|
|
|
regulation of multicellular organismal development
|
GO:2000026 |
414 |
0.011
|
|
|
regulation of multi organism process
|
GO:0043900 |
131 |
0.011
|
|
|
purine nucleotide catabolic process
|
GO:0006195 |
109 |
0.011
|
|
|
chromatin organization
|
GO:0006325 |
207 |
0.011
|
|
|
regulation of immune response
|
GO:0050776 |
118 |
0.011
|
|
|
defense response to other organism
|
GO:0098542 |
225 |
0.011
|
|
|
purine ribonucleoside monophosphate catabolic process
|
GO:0009169 |
38 |
0.011
|
|
|
sex differentiation
|
GO:0007548 |
81 |
0.011
|
|
|
atp catabolic process
|
GO:0006200 |
38 |
0.011
|
|
|
locomotory behavior
|
GO:0007626 |
176 |
0.011
|
|
|
protein localization
|
GO:0008104 |
284 |
0.010
|
|
|
phosphorylation
|
GO:0016310 |
294 |
0.010
|
|
|
positive regulation of synaptic growth at neuromuscular junction
|
GO:0045887 |
26 |
0.010
|
|
|
positive regulation of cellular component biogenesis
|
GO:0044089 |
80 |
0.010
|
|
|
intracellular signal transduction
|
GO:0035556 |
300 |
0.010
|
|
|
ribonucleoside triphosphate catabolic process
|
GO:0009203 |
108 |
0.010
|
|
|
regulation of protein import into nucleus
|
GO:0042306 |
28 |
0.010
|
|
|
regulation of cellular protein catabolic process
|
GO:1903362 |
44 |
0.010
|
Human Yeast |
|
positive regulation of programmed cell death
|
GO:0043068 |
62 |
0.010
|
|
|
positive regulation of cellular component organization
|
GO:0051130 |
156 |
0.010
|
|
|
spermatid differentiation
|
GO:0048515 |
114 |
0.010
|
|