Drosophila melanogaster

136 known processes

Cdk5alpha (Dmel_CG5387)

Cdk5 activator-like protein

(Aliases: dCdk5alpha,Dp35,CG5387,p35-21C,Dmp35,p35-31C,p25,D-p35,Cdk5a,p35,Dmel\CG5387,P35)

Cdk5alpha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
axon development GO:0061564 297 0.575
axonogenesis GO:0007409 290 0.522
cell migration GO:0016477 238 0.469
Mouse
muscle structure development GO:0061061 224 0.419
chemotaxis GO:0006935 249 0.369
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.336
regulation of localization GO:0032879 275 0.331
Mouse
neuron projection guidance GO:0097485 241 0.271
axon guidance GO:0007411 233 0.268
cell death GO:0008219 279 0.263
forebrain development GO:0030900 2 0.242
Mouse
localization of cell GO:0051674 257 0.238
Mouse
multicellular organismal aging GO:0010259 140 0.227
synaptic transmission GO:0007268 288 0.220
defense response GO:0006952 300 0.184
negative regulation of response to stimulus GO:0048585 258 0.182
regulation of response to stress GO:0080134 200 0.181
negative regulation of cellular metabolic process GO:0031324 382 0.169
spermatogenesis GO:0007283 200 0.163
signal release GO:0023061 49 0.157
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.156
Mouse
small molecule metabolic process GO:0044281 305 0.154
negative regulation of signal transduction GO:0009968 206 0.147
regulation of molecular function GO:0065009 217 0.141
carbohydrate derivative metabolic process GO:1901135 217 0.138
taxis GO:0042330 304 0.136
regulation of neuron differentiation GO:0045664 103 0.135
Mouse
aging GO:0007568 143 0.134
lateral inhibition GO:0046331 206 0.129
glycosyl compound metabolic process GO:1901657 127 0.127
regulation of cell morphogenesis GO:0022604 163 0.120
Mouse
regulation of anatomical structure morphogenesis GO:0022603 242 0.112
Mouse
cellular catabolic process GO:0044248 372 0.110
nucleoside phosphate metabolic process GO:0006753 162 0.108
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.103
microtubule based transport GO:0010970 42 0.100
ribonucleoside triphosphate metabolic process GO:0009199 119 0.100
determination of adult lifespan GO:0008340 137 0.100
organic substance catabolic process GO:1901575 308 0.098
purine containing compound metabolic process GO:0072521 155 0.097
organonitrogen compound metabolic process GO:1901564 318 0.096
ribonucleoside triphosphate catabolic process GO:0009203 108 0.095
growth GO:0040007 359 0.095
Mouse
positive regulation of gtpase activity GO:0043547 43 0.094
nucleoside phosphate catabolic process GO:1901292 110 0.091
extrinsic apoptotic signaling pathway GO:0097191 1 0.089
negative regulation of cell differentiation GO:0045596 143 0.088
Mouse
single organism catabolic process GO:0044712 228 0.088
developmental growth GO:0048589 280 0.087
Mouse
negative regulation of signaling GO:0023057 219 0.087
secretion GO:0046903 109 0.086
protein complex biogenesis GO:0070271 201 0.085
cellular macromolecular complex assembly GO:0034622 153 0.084
purine nucleoside catabolic process GO:0006152 112 0.084
programmed cell death GO:0012501 257 0.083
negative regulation of nervous system development GO:0051961 92 0.083
Mouse
actin cytoskeleton organization GO:0030036 206 0.082
Mouse
regulation of catabolic process GO:0009894 170 0.081
positive regulation of apoptotic signaling pathway GO:2001235 4 0.079
epithelial cell differentiation GO:0030855 322 0.078
positive regulation of catalytic activity GO:0043085 118 0.077
purine ribonucleotide metabolic process GO:0009150 145 0.077
adult locomotory behavior GO:0008344 76 0.077
regulation of cellular catabolic process GO:0031329 157 0.075
catabolic process GO:0009056 409 0.075
intracellular signal transduction GO:0035556 300 0.075
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.075
motor neuron axon guidance GO:0008045 58 0.074
single organism behavior GO:0044708 391 0.074
tissue migration GO:0090130 155 0.071
positive regulation of molecular function GO:0044093 136 0.070
nucleobase containing small molecule metabolic process GO:0055086 174 0.068
negative regulation of nucleic acid templated transcription GO:1903507 240 0.067
nucleoside catabolic process GO:0009164 112 0.066
head development GO:0060322 135 0.066
Mouse
positive regulation of cellular protein metabolic process GO:0032270 118 0.065
nucleotide metabolic process GO:0009117 161 0.065
regulation of cell motility GO:2000145 23 0.063
positive regulation of cell migration GO:0030335 2 0.060
single organism intracellular transport GO:1902582 207 0.060
Mouse
organonitrogen compound catabolic process GO:1901565 128 0.060
purine nucleoside metabolic process GO:0042278 127 0.060
nucleoside triphosphate metabolic process GO:0009141 120 0.059
regulation of synaptic plasticity GO:0048167 14 0.059
intracellular transport GO:0046907 228 0.058
Mouse
neurotransmitter transport GO:0006836 37 0.057
ribonucleoside metabolic process GO:0009119 127 0.057
vesicle organization GO:0016050 44 0.057
vesicle localization GO:0051648 55 0.057
negative regulation of developmental process GO:0051093 201 0.057
Mouse
organelle localization GO:0051640 148 0.057
microtubule based movement GO:0007018 51 0.056
guanosine containing compound catabolic process GO:1901069 74 0.054
response to oxygen containing compound GO:1901700 200 0.053
respiratory system development GO:0060541 213 0.053
regulation of protein metabolic process GO:0051246 256 0.053
neurological system process GO:0050877 358 0.052
glycosyl compound catabolic process GO:1901658 112 0.052
regulation of multicellular organismal development GO:2000026 414 0.052
Mouse
establishment of vesicle localization GO:0051650 51 0.052
enzyme linked receptor protein signaling pathway GO:0007167 179 0.050
Mouse
negative regulation of cell communication GO:0010648 223 0.050
positive regulation of response to stimulus GO:0048584 323 0.050
regulation of synaptic transmission GO:0050804 69 0.049
regulation of cell death GO:0010941 173 0.049
regulation of neurotransmitter levels GO:0001505 38 0.048
secretion by cell GO:0032940 101 0.048
purine nucleoside triphosphate metabolic process GO:0009144 119 0.048
carbohydrate derivative catabolic process GO:1901136 118 0.048
establishment of synaptic vesicle localization GO:0097480 50 0.047
regulation of hydrolase activity GO:0051336 97 0.047
macromolecular complex assembly GO:0065003 256 0.047
regulation of cell projection organization GO:0031344 92 0.047
Mouse
positive regulation of developmental process GO:0051094 143 0.047
muscle organ development GO:0007517 127 0.046
negative regulation of molecular function GO:0044092 51 0.046
guanosine containing compound metabolic process GO:1901068 74 0.046
synaptic vesicle localization GO:0097479 53 0.045
histone modification GO:0016570 106 0.044
stem cell division GO:0017145 69 0.044
synaptic growth at neuromuscular junction GO:0051124 119 0.044
learning or memory GO:0007611 141 0.043
ribose phosphate metabolic process GO:0019693 145 0.042
ribonucleotide metabolic process GO:0009259 145 0.042
cellular protein modification process GO:0006464 438 0.042
male gamete generation GO:0048232 201 0.042
brain development GO:0007420 120 0.042
Mouse
endocytosis GO:0006897 310 0.041
locomotory behavior GO:0007626 176 0.041
regulation of cellular response to stress GO:0080135 89 0.041
protein complex assembly GO:0006461 200 0.041
ribonucleotide catabolic process GO:0009261 109 0.041
ion transport GO:0006811 145 0.040
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.040
developmental maturation GO:0021700 172 0.039
Mouse
gtp metabolic process GO:0046039 72 0.038
organophosphate metabolic process GO:0019637 195 0.038
organ growth GO:0035265 56 0.038
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.038
response to organic substance GO:0010033 284 0.038
ras protein signal transduction GO:0007265 88 0.038
purine ribonucleotide catabolic process GO:0009154 109 0.038
regulation of catalytic activity GO:0050790 185 0.038
rho protein signal transduction GO:0007266 14 0.037
neurotransmitter secretion GO:0007269 35 0.037
regulation of cell cycle GO:0051726 291 0.036
Mouse
regulation of cellular protein metabolic process GO:0032268 243 0.036
notch signaling pathway GO:0007219 120 0.036
negative regulation of rna biosynthetic process GO:1902679 240 0.036
regulation of response to external stimulus GO:0032101 115 0.036
positive regulation of cellular catabolic process GO:0031331 95 0.036
regulation of locomotion GO:0040012 42 0.036
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.035
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.035
adult behavior GO:0030534 137 0.035
purine nucleoside triphosphate catabolic process GO:0009146 108 0.035
regulation of transferase activity GO:0051338 58 0.035
cellular protein complex assembly GO:0043623 71 0.035
positive regulation of protein metabolic process GO:0051247 128 0.034
protein import into nucleus GO:0006606 51 0.034
hindbrain development GO:0030902 2 0.033
Mouse
negative regulation of cellular protein metabolic process GO:0032269 85 0.033
protein localization GO:0008104 284 0.033
Mouse
immune system process GO:0002376 347 0.033
skeletal muscle organ development GO:0060538 48 0.033
chromatin organization GO:0006325 207 0.032
nucleotide catabolic process GO:0009166 109 0.032
purine nucleotide catabolic process GO:0006195 109 0.032
nucleobase containing compound catabolic process GO:0034655 165 0.032
positive regulation of signal transduction GO:0009967 223 0.032
purine ribonucleoside metabolic process GO:0046128 127 0.032
biological adhesion GO:0022610 138 0.031
Mouse
regulation of tube size GO:0035150 46 0.031
neuron recognition GO:0008038 101 0.031
Mouse
positive regulation of hydrolase activity GO:0051345 78 0.031
organelle fusion GO:0048284 46 0.031
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.030
nucleoside metabolic process GO:0009116 127 0.030
positive regulation of cellular component organization GO:0051130 156 0.030
Mouse
organic cyclic compound catabolic process GO:1901361 168 0.030
gtp catabolic process GO:0006184 72 0.030
positive regulation of multicellular organismal process GO:0051240 143 0.030
regulation of intracellular signal transduction GO:1902531 236 0.030
Mouse
translation GO:0006412 69 0.030
protein catabolic process GO:0030163 101 0.029
cell proliferation GO:0008283 299 0.029
regulation of cellular component biogenesis GO:0044087 201 0.029
response to external biotic stimulus GO:0043207 293 0.028
phosphorylation GO:0016310 294 0.028
cellular protein localization GO:0034613 160 0.028
Mouse
purine ribonucleoside catabolic process GO:0046130 112 0.028
regulation of immune system process GO:0002682 176 0.028
terminal button organization GO:0072553 19 0.028
single organism cellular localization GO:1902580 180 0.028
Mouse
establishment of protein localization GO:0045184 163 0.028
Mouse
nitrogen compound transport GO:0071705 85 0.028
nucleoside triphosphate catabolic process GO:0009143 108 0.027
establishment of localization in cell GO:0051649 402 0.027
Mouse
regulation of nervous system development GO:0051960 248 0.027
Mouse
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.027
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.027
Mouse
single organism membrane organization GO:0044802 93 0.027
Mouse
positive regulation of signaling GO:0023056 243 0.027
cellular amide metabolic process GO:0043603 80 0.026
cellular amino acid metabolic process GO:0006520 61 0.026
ameboidal type cell migration GO:0001667 151 0.026
cell division GO:0051301 248 0.026
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
positive regulation of macromolecule metabolic process GO:0010604 405 0.026
retina development in camera type eye GO:0060041 4 0.026
Zebrafish
organophosphate catabolic process GO:0046434 112 0.025
membrane organization GO:0061024 112 0.025
Mouse
mapk cascade GO:0000165 107 0.025
establishment of organelle localization GO:0051656 122 0.025
covalent chromatin modification GO:0016569 106 0.025
regulation of cell differentiation GO:0045595 302 0.025
Mouse
photoreceptor cell axon guidance GO:0072499 23 0.025
epithelial cell development GO:0002064 274 0.025
cytoskeleton dependent intracellular transport GO:0030705 44 0.024
synaptic vesicle recycling GO:0036465 28 0.024
immune system development GO:0002520 57 0.024
necrotic cell death GO:0070265 1 0.024
nuclear transport GO:0051169 72 0.024
death GO:0016265 284 0.024
dopamine metabolic process GO:0042417 7 0.024
mitochondrion organization GO:0007005 65 0.024
sensory perception of sound GO:0007605 56 0.023
muscle tissue development GO:0060537 30 0.023
negative regulation of transcription dna templated GO:0045892 237 0.023
regulation of cell development GO:0060284 215 0.023
Mouse
regulation of apoptotic process GO:0042981 130 0.023
purine nucleotide metabolic process GO:0006163 146 0.023
embryonic axis specification GO:0000578 107 0.022
connective tissue development GO:0061448 3 0.022
response to oxidative stress GO:0006979 86 0.022
dendrite morphogenesis GO:0048813 199 0.022
Mouse
peptidyl amino acid modification GO:0018193 105 0.022
Mouse
signal transduction by phosphorylation GO:0023014 107 0.022
regulation of gtpase activity GO:0043087 44 0.022
cation transmembrane transport GO:0098655 88 0.022
wnt signaling pathway GO:0016055 98 0.022
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.022
cellular amine metabolic process GO:0044106 12 0.022
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.021
dendrite guidance GO:0070983 21 0.021
regulation of cellular component movement GO:0051270 42 0.021
regulation of establishment of protein localization GO:0070201 61 0.021
Mouse
stress activated protein kinase signaling cascade GO:0031098 55 0.021
mesenchymal cell development GO:0014031 1 0.021
synaptic vesicle endocytosis GO:0048488 28 0.021
negative regulation of cellular component organization GO:0051129 108 0.021
Mouse
synaptic target recognition GO:0008039 45 0.020
cytoplasmic transport GO:0016482 130 0.020
regulation of cytoskeleton organization GO:0051493 89 0.020
Mouse
sensory perception GO:0007600 196 0.020
neuromuscular junction development GO:0007528 149 0.020
cellular pigmentation GO:0033059 12 0.020
positive regulation of cell development GO:0010720 61 0.020
cellular nitrogen compound catabolic process GO:0044270 165 0.020
negative regulation of rna metabolic process GO:0051253 251 0.020
tissue morphogenesis GO:0048729 297 0.020
Zebrafish
apoptotic process GO:0006915 159 0.020
regulation of circadian sleep wake cycle GO:0042749 25 0.019
response to other organism GO:0051707 293 0.019
nuclear division GO:0000280 332 0.019
protein phosphorylation GO:0006468 169 0.019
kidney development GO:0001822 3 0.019
negative regulation of mitotic cell cycle GO:0045930 109 0.019
endomembrane system organization GO:0010256 119 0.019
positive regulation of cell communication GO:0010647 250 0.019
outflow tract morphogenesis GO:0003151 4 0.019
eye photoreceptor cell differentiation GO:0001754 145 0.019
regulation of growth GO:0040008 233 0.019
Mouse
organic substance transport GO:0071702 257 0.019
Mouse
axon target recognition GO:0007412 16 0.019
regulation of cellular ketone metabolic process GO:0010565 3 0.018
camera type eye development GO:0043010 4 0.018
Zebrafish
vesicle mediated transport GO:0016192 381 0.018
body morphogenesis GO:0010171 2 0.018
stem cell development GO:0048864 79 0.018
phagocytosis GO:0006909 215 0.018
metal ion transport GO:0030001 74 0.018
epidermal growth factor receptor signaling pathway GO:0007173 58 0.018
stress activated mapk cascade GO:0051403 52 0.018
synaptic vesicle transport GO:0048489 50 0.018
cell cycle phase transition GO:0044770 140 0.018
organelle assembly GO:0070925 198 0.018
proteolysis GO:0006508 192 0.018
positive regulation of neuron differentiation GO:0045666 26 0.018
regulation of notch signaling pathway GO:0008593 100 0.018
embryonic development via the syncytial blastoderm GO:0001700 148 0.018
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.017
regulation of nucleotide metabolic process GO:0006140 62 0.017
telencephalon development GO:0021537 2 0.017
Mouse
protein complex disassembly GO:0043241 36 0.017
cortical cytoskeleton organization GO:0030865 29 0.017
negative regulation of catalytic activity GO:0043086 42 0.017
small gtpase mediated signal transduction GO:0007264 88 0.017
cytoplasmic microtubule organization GO:0031122 22 0.017
cell recognition GO:0008037 102 0.017
Mouse
neuron neuron synaptic transmission GO:0007270 14 0.017
heterocycle catabolic process GO:0046700 166 0.017
cell maturation GO:0048469 144 0.017
cellular component disassembly GO:0022411 46 0.017
negative regulation of neurogenesis GO:0050768 53 0.017
Mouse
positive regulation of catabolic process GO:0009896 105 0.017
defense response to other organism GO:0098542 225 0.017
intracellular protein transport GO:0006886 104 0.017
Mouse
striated muscle myosin thick filament assembly GO:0071688 3 0.016
eye morphogenesis GO:0048592 260 0.016
Zebrafish
organic acid metabolic process GO:0006082 103 0.016
regulation of developmental growth GO:0048638 174 0.016
Mouse
olfactory bulb axon guidance GO:0071678 3 0.016
positive regulation of cell motility GO:2000147 3 0.016
purine containing compound catabolic process GO:0072523 112 0.016
response to abiotic stimulus GO:0009628 341 0.016
regulation of neuron death GO:1901214 26 0.016
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.016
ion transmembrane transport GO:0034220 122 0.016
activation of innate immune response GO:0002218 4 0.016
positive regulation of biosynthetic process GO:0009891 316 0.016
ribonucleoside catabolic process GO:0042454 112 0.016
cardiovascular system development GO:0072358 82 0.016
negative regulation of epithelial cell proliferation GO:0050680 4 0.016
negative regulation of protein metabolic process GO:0051248 85 0.016
peripheral nervous system development GO:0007422 52 0.016
positive regulation of nucleoside metabolic process GO:0045979 47 0.016
cellular response to dna damage stimulus GO:0006974 223 0.016
innate immune response GO:0045087 144 0.016
regulation of cellular response to growth factor stimulus GO:0090287 13 0.016
cell cell signaling involved in cell fate commitment GO:0045168 210 0.015
development of primary sexual characteristics GO:0045137 50 0.015
posttranscriptional regulation of gene expression GO:0010608 145 0.015
positive regulation of neurogenesis GO:0050769 41 0.015
positive regulation of transcription dna templated GO:0045893 266 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
positive regulation of phosphate metabolic process GO:0045937 139 0.015
defense response to bacterium GO:0042742 178 0.015
erbb signaling pathway GO:0038127 58 0.015
response to biotic stimulus GO:0009607 294 0.015
kidney epithelium development GO:0072073 3 0.015
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.015
regulation of circadian rhythm GO:0042752 49 0.015
regulation of microtubule based process GO:0032886 49 0.015
Mouse
regulation of programmed cell death GO:0043067 152 0.015
regulation of cell shape GO:0008360 113 0.015
immune response regulating signaling pathway GO:0002764 2 0.015
collateral sprouting GO:0048668 3 0.015
response to drug GO:0042493 17 0.015
regulation of purine nucleotide metabolic process GO:1900542 62 0.014
negative regulation of cell cell adhesion GO:0022408 8 0.014
regulation of reactive oxygen species metabolic process GO:2000377 8 0.014
protein targeting GO:0006605 64 0.014
Mouse
regulation of cellular amine metabolic process GO:0033238 3 0.014
myofibril assembly GO:0030239 36 0.014
regulation of cellular localization GO:0060341 136 0.014
Mouse
regulation of multi organism process GO:0043900 131 0.014
positive regulation of cellular component biogenesis GO:0044089 80 0.014
cognition GO:0050890 141 0.014
mating behavior GO:0007617 106 0.014
dendrite development GO:0016358 204 0.014
Mouse
larval development GO:0002164 104 0.014
synaptic transmission gabaergic GO:0051932 1 0.014
positive regulation of behavior GO:0048520 19 0.014
negative regulation of cell cycle GO:0045786 116 0.014
Mouse
immune response GO:0006955 246 0.014
regulation of protein import into nucleus GO:0042306 28 0.014
response to axon injury GO:0048678 12 0.014
oxoacid metabolic process GO:0043436 103 0.014
regulation of synapse organization GO:0050807 110 0.014
ribonucleoprotein complex assembly GO:0022618 23 0.014
regulation of defense response GO:0031347 102 0.014
carboxylic acid metabolic process GO:0019752 92 0.014
response to light stimulus GO:0009416 124 0.014
sensory perception of smell GO:0007608 80 0.014
regulation of behavior GO:0050795 75 0.013
catechol containing compound biosynthetic process GO:0009713 3 0.013
cellular ketone metabolic process GO:0042180 24 0.013
endosomal transport GO:0016197 44 0.013
gland development GO:0048732 191 0.013
nucleocytoplasmic transport GO:0006913 72 0.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress GO:0070059 4 0.013
negative regulation of canonical wnt signaling pathway GO:0090090 6 0.013
protein targeting to nucleus GO:0044744 51 0.013
neuron fate commitment GO:0048663 50 0.013
protein import GO:0017038 55 0.013
segmentation GO:0035282 207 0.013
regulation of rho protein signal transduction GO:0035023 20 0.013
cellular response to chemical stimulus GO:0070887 199 0.013
positive regulation of rna metabolic process GO:0051254 271 0.013
cranial nerve development GO:0021545 1 0.013
circadian sleep wake cycle process GO:0022410 24 0.013
regulation of wnt signaling pathway GO:0030111 68 0.013
instar larval development GO:0002168 55 0.013
nephron tubule development GO:0072080 3 0.013
cell fate determination GO:0001709 91 0.013
catecholamine biosynthetic process GO:0042423 3 0.013
regulation of neurogenesis GO:0050767 158 0.013
Mouse
cellular protein complex disassembly GO:0043624 35 0.013
regulation of proteolysis GO:0030162 87 0.013
single organism nuclear import GO:1902593 51 0.013
negative regulation of sequence specific dna binding transcription factor activity GO:0043433 4 0.013
regulation of nucleocytoplasmic transport GO:0046822 35 0.013
chromatin modification GO:0016568 147 0.012
regulation of transport GO:0051049 181 0.012
Mouse
chromatin remodeling GO:0006338 72 0.012
dopamine receptor signaling pathway GO:0007212 4 0.012
negative regulation of epidermal growth factor receptor signaling pathway GO:0042059 29 0.012
regulation of mapk cascade GO:0043408 92 0.012
extracellular structure organization GO:0043062 46 0.012
cellular response to biotic stimulus GO:0071216 4 0.012
peripheral nervous system neuron differentiation GO:0048934 8 0.012
positive regulation of cellular biosynthetic process GO:0031328 316 0.012
multicellular organismal metabolic process GO:0044236 1 0.012
transcription from rna polymerase ii promoter GO:0006366 368 0.012
cytokinesis GO:0000910 90 0.012
positive regulation of neuron apoptotic process GO:0043525 1 0.012
regulation of axonogenesis GO:0050770 32 0.012
Mouse
jak stat cascade GO:0007259 49 0.012
amine metabolic process GO:0009308 12 0.012
dorsal ventral axis specification GO:0009950 66 0.012
negative regulation of intracellular signal transduction GO:1902532 57 0.012
positive regulation of reactive oxygen species metabolic process GO:2000379 0 0.012
positive regulation of cell death GO:0010942 69 0.012
asymmetric stem cell division GO:0098722 49 0.012
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.012
synaptic vesicle fusion to presynaptic membrane GO:0031629 7 0.012
inositol lipid mediated signaling GO:0048017 4 0.012
peptidyl threonine phosphorylation GO:0018107 2 0.012
regulation of cell migration GO:0030334 22 0.011
histone acetylation GO:0016573 38 0.011
internal peptidyl lysine acetylation GO:0018393 38 0.011
reproductive structure development GO:0048608 74 0.011
internal protein amino acid acetylation GO:0006475 38 0.011
cell cycle arrest GO:0007050 4 0.011
Mouse
hematopoietic or lymphoid organ development GO:0048534 57 0.011
tripartite regional subdivision GO:0007351 103 0.011
compound eye photoreceptor cell differentiation GO:0001751 140 0.011
regulation of cellular component size GO:0032535 98 0.011
Mouse
regulation of organelle organization GO:0033043 196 0.011
Mouse
cell adhesion GO:0007155 136 0.011
Mouse
regulation of purine nucleotide catabolic process GO:0033121 48 0.011
protein localization to organelle GO:0033365 82 0.011
regulation of autophagy GO:0010506 62 0.011
cell cycle checkpoint GO:0000075 95 0.011
response to radiation GO:0009314 155 0.011
mushroom body development GO:0016319 70 0.011
regulation of immune response GO:0050776 118 0.011
urogenital system development GO:0001655 72 0.011
positive regulation of cellular amine metabolic process GO:0033240 0 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
dephosphorylation GO:0016311 51 0.011
central nervous system development GO:0007417 201 0.011
Mouse
rna localization GO:0006403 115 0.011
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.011
regulation of protein ubiquitination GO:0031396 22 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
reproductive behavior GO:0019098 122 0.011
negative regulation of multicellular organismal process GO:0051241 142 0.011
Mouse
protein acetylation GO:0006473 39 0.011
stem cell proliferation GO:0072089 88 0.011
sterol homeostasis GO:0055092 4 0.011
regulation of neuron apoptotic process GO:0043523 16 0.011
atp biosynthetic process GO:0006754 2 0.011
somatic stem cell division GO:0048103 37 0.011
embryo development ending in birth or egg hatching GO:0009792 152 0.011
regulation of phosphorylation GO:0042325 147 0.010
photoreceptor cell fate commitment GO:0046552 41 0.010
neuron maturation GO:0042551 31 0.010
cell fate specification GO:0001708 71 0.010
response to copper ion GO:0046688 4 0.010
positive regulation of ras gtpase activity GO:0032320 36 0.010
phosphatidylinositol 3 kinase signaling GO:0014065 4 0.010
protein localization to nucleus GO:0034504 55 0.010
negative regulation of neuron death GO:1901215 18 0.010
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.010
membrane fusion GO:0061025 42 0.010
establishment of protein localization to organelle GO:0072594 62 0.010
organelle fission GO:0048285 340 0.010
positive regulation of nucleotide catabolic process GO:0030813 46 0.010
vesicle fusion GO:0006906 19 0.010
multi organism reproductive behavior GO:0044705 121 0.010

Cdk5alpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.047
nervous system disease DOID:863 0 0.022
cancer DOID:162 0 0.019
disease of cellular proliferation DOID:14566 0 0.019
sensory system disease DOID:0050155 0 0.016
eye and adnexa disease DOID:1492 0 0.016
eye disease DOID:5614 0 0.016
organ system cancer DOID:0050686 0 0.014
musculoskeletal system disease DOID:17 0 0.012
muscular disease DOID:0080000 0 0.011
central nervous system disease DOID:331 0 0.010
neurodegenerative disease DOID:1289 0 0.010