Drosophila melanogaster

17 known processes

Mio (Dmel_CG18362)

Mlx interactor

(Aliases: dmondo,Dmel\CG18362,anon-39Da,154826_at,bHLHd12,CG18362)

Mio biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
feeding behavior GO:0007631 50 0.879
centrosome duplication GO:0051298 121 0.505
circadian rhythm GO:0007623 105 0.385
organelle assembly GO:0070925 198 0.362
adult feeding behavior GO:0008343 13 0.303
multi organism reproductive behavior GO:0044705 121 0.297
regulation of growth GO:0040008 233 0.220
single organism behavior GO:0044708 391 0.213
microtubule organizing center organization GO:0031023 168 0.211
organelle localization GO:0051640 148 0.195
centrosome organization GO:0051297 163 0.178
adult behavior GO:0030534 137 0.176
male mating behavior GO:0060179 70 0.166
larval feeding behavior GO:0030536 15 0.163
establishment of organelle localization GO:0051656 122 0.155
male courtship behavior GO:0008049 63 0.134
multicellular organism growth GO:0035264 46 0.119
developmental growth GO:0048589 280 0.119
germarium derived egg chamber formation GO:0007293 101 0.100
response to extracellular stimulus GO:0009991 116 0.100
regulation of developmental growth GO:0048638 174 0.096
meiotic nuclear division GO:0007126 151 0.091
cellular component disassembly GO:0022411 46 0.082
centrosome cycle GO:0007098 137 0.079
positive regulation of signal transduction GO:0009967 223 0.078
spindle localization GO:0051653 22 0.077
asymmetric neuroblast division GO:0055059 33 0.076
establishment of localization in cell GO:0051649 402 0.070
positive regulation of signaling GO:0023056 243 0.070
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.066
establishment or maintenance of cell polarity GO:0007163 167 0.065
positive regulation of response to stimulus GO:0048584 323 0.063
positive regulation of developmental growth GO:0048639 62 0.061
regulation of response to extracellular stimulus GO:0032104 18 0.057
cuticle development GO:0042335 86 0.057
response to external biotic stimulus GO:0043207 293 0.056
oocyte fate determination GO:0030716 27 0.054
body morphogenesis GO:0010171 2 0.053
germarium derived oocyte fate determination GO:0007294 26 0.053
oocyte localization involved in germarium derived egg chamber formation GO:0030720 12 0.053
single organism biosynthetic process GO:0044711 206 0.052
centriole replication GO:0007099 24 0.052
cell proliferation GO:0008283 299 0.051
ovarian fusome organization GO:0030723 11 0.051
positive regulation of cell communication GO:0010647 250 0.050
female meiotic division GO:0007143 70 0.050
centriole assembly GO:0098534 24 0.050
meiotic cell cycle process GO:1903046 132 0.050
response to nutrient levels GO:0031667 114 0.048
centriole centriole cohesion GO:0010457 5 0.047
growth GO:0040007 359 0.047
protein complex disassembly GO:0043241 36 0.046
oxidation reduction process GO:0055114 123 0.045
developmental maturation GO:0021700 172 0.045
defense response to gram positive bacterium GO:0050830 41 0.044
defense response to bacterium GO:0042742 178 0.044
rhythmic process GO:0048511 106 0.043
intracellular signal transduction GO:0035556 300 0.043
regulation of cell cycle GO:0051726 291 0.042
response to abiotic stimulus GO:0009628 341 0.041
chemical homeostasis GO:0048878 92 0.040
positive regulation of feeding behavior GO:2000253 8 0.040
circadian behavior GO:0048512 76 0.040
response to endogenous stimulus GO:0009719 119 0.040
oocyte axis specification GO:0007309 108 0.039
eggshell chorion assembly GO:0007306 66 0.038
organic acid metabolic process GO:0006082 103 0.037
locomotory behavior GO:0007626 176 0.036
chromosome organization GO:0051276 360 0.036
regulation of mitotic cell cycle GO:0007346 190 0.036
neuroblast division GO:0055057 35 0.036
g protein coupled receptor signaling pathway GO:0007186 136 0.035
oocyte nucleus localization involved in oocyte dorsal ventral axis specification GO:0051663 12 0.034
germarium derived oocyte differentiation GO:0030706 29 0.034
regulation of response to nutrient levels GO:0032107 18 0.033
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.032
meiosis i GO:0007127 59 0.031
cellular component assembly involved in morphogenesis GO:0010927 151 0.031
microtubule polymerization or depolymerization GO:0031109 39 0.030
neuropeptide signaling pathway GO:0007218 45 0.030
membrane fusion GO:0061025 42 0.030
sister chromatid segregation GO:0000819 92 0.029
response to light stimulus GO:0009416 124 0.029
mating behavior sex discrimination GO:0048047 7 0.029
positive regulation of multicellular organism growth GO:0040018 21 0.028
response to desiccation GO:0009269 3 0.028
response to water deprivation GO:0009414 4 0.027
segmentation GO:0035282 207 0.027
positive regulation of intracellular signal transduction GO:1902533 116 0.027
macromolecular complex disassembly GO:0032984 37 0.026
positive regulation of biosynthetic process GO:0009891 316 0.026
oxoacid metabolic process GO:0043436 103 0.026
lipid localization GO:0010876 54 0.026
intracellular transport GO:0046907 228 0.026
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
phosphorylation GO:0016310 294 0.025
establishment of cell polarity GO:0030010 40 0.025
multi multicellular organism process GO:0044706 123 0.025
oocyte dorsal ventral axis specification GO:0007310 34 0.025
endomembrane system organization GO:0010256 119 0.025
oocyte microtubule cytoskeleton organization GO:0016325 35 0.025
chorion containing eggshell formation GO:0007304 105 0.025
male meiosis GO:0007140 52 0.024
microtubule bundle formation GO:0001578 27 0.024
cytoplasmic transport nurse cell to oocyte GO:0007303 12 0.023
positive regulation of rna metabolic process GO:0051254 271 0.022
regulation of translation GO:0006417 56 0.022
endocytosis GO:0006897 310 0.022
chromosome localization GO:0050000 20 0.022
posttranscriptional regulation of gene expression GO:0010608 145 0.022
wing disc morphogenesis GO:0007472 344 0.022
post embryonic appendage morphogenesis GO:0035120 385 0.022
oocyte differentiation GO:0009994 145 0.022
response to starvation GO:0042594 97 0.021
regulation of intracellular signal transduction GO:1902531 236 0.021
response to other organism GO:0051707 293 0.021
positive regulation of multicellular organismal process GO:0051240 143 0.020
peroxisome organization GO:0007031 14 0.020
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.020
cilium organization GO:0044782 41 0.020
regulation of immune system process GO:0002682 176 0.019
regulation of multicellular organism growth GO:0040014 40 0.019
regulation of localization GO:0032879 275 0.019
positive regulation of developmental process GO:0051094 143 0.019
regulation of autophagy GO:0010506 62 0.019
positive regulation of cell size GO:0045793 21 0.019
autophagic cell death GO:0048102 83 0.018
small molecule metabolic process GO:0044281 305 0.018
negative regulation of cell cycle phase transition GO:1901988 103 0.018
actin filament based process GO:0030029 220 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
cystoblast division GO:0007282 10 0.018
neurological system process GO:0050877 358 0.018
cytoplasmic microtubule organization GO:0031122 22 0.018
catabolic process GO:0009056 409 0.018
cellular protein localization GO:0034613 160 0.017
regulation of anatomical structure size GO:0090066 163 0.017
autophagy GO:0006914 108 0.017
defense response to other organism GO:0098542 225 0.017
response to oxygen containing compound GO:1901700 200 0.017
regionalization GO:0003002 416 0.016
multi organism behavior GO:0051705 175 0.016
regulation of cellular localization GO:0060341 136 0.016
innate immune response GO:0045087 144 0.016
organelle fission GO:0048285 340 0.015
cell fate determination GO:0001709 91 0.015
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.015
microtubule polymerization GO:0046785 15 0.015
regulation of microtubule based process GO:0032886 49 0.015
actin cytoskeleton organization GO:0030036 206 0.015
amine metabolic process GO:0009308 12 0.015
double strand break repair GO:0006302 26 0.014
regulation of microtubule cytoskeleton organization GO:0070507 41 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
positive regulation of gene expression GO:0010628 290 0.014
fusome organization GO:0045478 13 0.014
oocyte construction GO:0007308 112 0.014
dna repair GO:0006281 54 0.014
tissue death GO:0016271 102 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
microtubule anchoring GO:0034453 11 0.013
regulation of protein metabolic process GO:0051246 256 0.013
response to organic substance GO:0010033 284 0.013
pyridine nucleotide metabolic process GO:0019362 2 0.013
regulation of multi organism process GO:0043900 131 0.013
carbohydrate homeostasis GO:0033500 12 0.013
stem cell division GO:0017145 69 0.013
behavioral response to starvation GO:0042595 6 0.013
positive regulation of transport GO:0051050 92 0.013
oocyte development GO:0048599 124 0.013
carboxylic acid metabolic process GO:0019752 92 0.013
meiotic chromosome segregation GO:0045132 59 0.013
protein depolymerization GO:0051261 31 0.012
establishment of spindle localization GO:0051293 22 0.012
negative regulation of wnt signaling pathway GO:0030178 28 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
neural precursor cell proliferation GO:0061351 75 0.012
mitotic nuclear division GO:0007067 213 0.012
negative regulation of cytoskeleton organization GO:0051494 30 0.012
mapk cascade GO:0000165 107 0.012
gland development GO:0048732 191 0.012
dorsal ventral axis specification GO:0009950 66 0.012
mitotic centrosome separation GO:0007100 8 0.012
positive regulation of phosphorylation GO:0042327 87 0.012
immune response GO:0006955 246 0.012
response to radiation GO:0009314 155 0.012
dna metabolic process GO:0006259 227 0.011
anterior posterior axis specification GO:0009948 109 0.011
cell death GO:0008219 279 0.011
macromolecule catabolic process GO:0009057 161 0.011
negative regulation of gene expression GO:0010629 387 0.011
positive regulation of growth GO:0045927 75 0.011
meiotic cell cycle GO:0051321 171 0.011
phosphatidylcholine metabolic process GO:0046470 3 0.011
mitotic spindle organization GO:0007052 220 0.011
positive regulation of cellular response to insulin stimulus GO:1900078 4 0.011
larval development GO:0002164 104 0.010
aging GO:0007568 143 0.010
regulation of nervous system development GO:0051960 248 0.010
long chain fatty acid metabolic process GO:0001676 3 0.010
mating behavior GO:0007617 106 0.010
phospholipase c activating g protein coupled receptor signaling pathway GO:0007200 10 0.010
axis specification GO:0009798 167 0.010
cellular ketone metabolic process GO:0042180 24 0.010
nuclear division GO:0000280 332 0.010

Mio disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.028
disease of metabolism DOID:0014667 0 0.014
inherited metabolic disorder DOID:655 0 0.014
sensory system disease DOID:0050155 0 0.012
eye and adnexa disease DOID:1492 0 0.012
nervous system disease DOID:863 0 0.012
eye disease DOID:5614 0 0.012
cancer DOID:162 0 0.012
disease of cellular proliferation DOID:14566 0 0.012