Drosophila melanogaster

16 known processes

CG5524 (Dmel_CG5524)

CG5524 gene product from transcript CG5524-RA

(Aliases: Dmel\CG5524)

CG5524 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
double strand break repair via nonhomologous end joining GO:0006303 5 0.985
dna geometric change GO:0032392 16 0.977
double strand break repair GO:0006302 26 0.937
double strand break repair via synthesis dependent strand annealing GO:0045003 6 0.910
non recombinational repair GO:0000726 7 0.882
dna repair GO:0006281 54 0.877
double strand break repair via homologous recombination GO:0000724 13 0.828
recombinational repair GO:0000725 13 0.784
mitotic dna damage checkpoint GO:0044773 74 0.767
mitotic g2 m transition checkpoint GO:0044818 70 0.713
mitotic g2 dna damage checkpoint GO:0007095 69 0.680
g2 dna damage checkpoint GO:0031572 69 0.651
dna biosynthetic process GO:0071897 24 0.621
cellular response to dna damage stimulus GO:0006974 223 0.592
dna duplex unwinding GO:0032508 16 0.576
regulation of dna repair GO:0006282 5 0.544
reciprocal meiotic recombination GO:0007131 19 0.509
translesion synthesis GO:0019985 2 0.494
dna damage checkpoint GO:0000077 78 0.474
mitotic recombination GO:0006312 2 0.457
Human
cell cycle dna replication GO:0044786 23 0.456
negative regulation of cell cycle GO:0045786 116 0.448
dna recombination GO:0006310 32 0.434
Human
dna replication GO:0006260 48 0.420
postreplication repair GO:0006301 2 0.414
dna synthesis involved in dna repair GO:0000731 5 0.403
dna double strand break processing GO:0000729 3 0.395
nucleotide excision repair GO:0006289 8 0.391
regulation of dna recombination GO:0000018 4 0.382
mitotic cell cycle checkpoint GO:0007093 88 0.372
telomere maintenance GO:0000723 21 0.368
Human
negative regulation of cell cycle phase transition GO:1901988 103 0.364
cellular response to abiotic stimulus GO:0071214 58 0.351
telomere organization GO:0032200 21 0.337
Human
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.333
atp metabolic process GO:0046034 49 0.310
mitotic cell cycle phase transition GO:0044772 138 0.305
dna metabolic process GO:0006259 227 0.272
Human
death GO:0016265 284 0.261
homeostatic process GO:0042592 199 0.247
Human
cell death GO:0008219 279 0.233
regulation of cell cycle phase transition GO:1901987 130 0.219
response to light stimulus GO:0009416 124 0.216
response to organic substance GO:0010033 284 0.183
response to abiotic stimulus GO:0009628 341 0.182
meiotic chromosome segregation GO:0045132 59 0.182
regulation of mitotic cell cycle GO:0007346 190 0.174
anatomical structure homeostasis GO:0060249 97 0.166
Human
regulation of dna metabolic process GO:0051052 34 0.162
cellular response to uv GO:0034644 12 0.153
glycosyl compound catabolic process GO:1901658 112 0.152
response to radiation GO:0009314 155 0.151
programmed cell death GO:0012501 257 0.146
regulation of double strand break repair GO:2000779 3 0.146
cell proliferation GO:0008283 299 0.144
negative regulation of mitotic cell cycle GO:0045930 109 0.140
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.133
positive regulation of cell death GO:0010942 69 0.131
cellular response to radiation GO:0071478 52 0.122
positive regulation of gene expression GO:0010628 290 0.110
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.108
nucleobase containing compound catabolic process GO:0034655 165 0.107
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.107
small molecule metabolic process GO:0044281 305 0.103
regulation of cell cycle process GO:0010564 181 0.101
regulation of programmed cell death GO:0043067 152 0.100
regulation of response to dna damage stimulus GO:2001020 23 0.096
positive regulation of cellular biosynthetic process GO:0031328 316 0.096
organelle fission GO:0048285 340 0.096
mitotic dna integrity checkpoint GO:0044774 75 0.095
single organism biosynthetic process GO:0044711 206 0.095
protein modification process GO:0036211 438 0.094
cellular catabolic process GO:0044248 372 0.093
positive regulation of programmed cell death GO:0043068 62 0.092
single organism catabolic process GO:0044712 228 0.091
regulation of cellular response to stress GO:0080135 89 0.090
catabolic process GO:0009056 409 0.088
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.087
intrinsic apoptotic signaling pathway in response to dna damage GO:0008630 11 0.086
cell cycle checkpoint GO:0000075 95 0.085
organic substance catabolic process GO:1901575 308 0.084
positive regulation of transcription dna templated GO:0045893 266 0.084
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.084
meiosis i GO:0007127 59 0.082
regulation of apoptotic process GO:0042981 130 0.081
cellular response to ionizing radiation GO:0071479 15 0.081
positive regulation of rna metabolic process GO:0051254 271 0.080
telomere capping GO:0016233 11 0.079
apoptotic process GO:0006915 159 0.079
heterocycle catabolic process GO:0046700 166 0.078
nuclear division GO:0000280 332 0.077
signal transduction in response to dna damage GO:0042770 3 0.074
ribonucleoside triphosphate metabolic process GO:0009199 119 0.073
reciprocal dna recombination GO:0035825 19 0.072
cell cycle phase transition GO:0044770 140 0.070
dna dependent dna replication GO:0006261 17 0.070
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.070
meiotic nuclear division GO:0007126 151 0.069
purine ribonucleoside monophosphate catabolic process GO:0009169 38 0.068
response to nitrogen compound GO:1901698 90 0.065
positive regulation of rna biosynthetic process GO:1902680 266 0.064
dna integrity checkpoint GO:0031570 81 0.064
regulation of cell death GO:0010941 173 0.061
positive regulation of biosynthetic process GO:0009891 316 0.060
response to uv GO:0009411 24 0.060
response to organonitrogen compound GO:0010243 75 0.060
regulation of cell proliferation GO:0042127 163 0.059
organic cyclic compound catabolic process GO:1901361 168 0.059
aromatic compound catabolic process GO:0019439 166 0.059
mitotic dna replication checkpoint GO:0033314 5 0.058
purine nucleoside monophosphate metabolic process GO:0009126 50 0.058
ribose phosphate metabolic process GO:0019693 145 0.057
ribonucleotide metabolic process GO:0009259 145 0.057
atp catabolic process GO:0006200 38 0.057
negative regulation of rna metabolic process GO:0051253 251 0.055
regulation of mitotic cell cycle phase transition GO:1901990 130 0.055
cellular protein modification process GO:0006464 438 0.054
positive regulation of signaling GO:0023056 243 0.052
negative regulation of biosynthetic process GO:0009890 277 0.052
ribonucleoside catabolic process GO:0042454 112 0.051
regulation of meiosis GO:0040020 3 0.050
ribonucleoside monophosphate metabolic process GO:0009161 51 0.050
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.050
regulation of cell cycle GO:0051726 291 0.049
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.049
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.049
imaginal disc derived appendage morphogenesis GO:0035114 395 0.048
purine nucleoside monophosphate catabolic process GO:0009128 38 0.048
ribonucleoside metabolic process GO:0009119 127 0.048
appendage development GO:0048736 401 0.047
positive regulation of macromolecule metabolic process GO:0010604 405 0.046
nucleoside triphosphate catabolic process GO:0009143 108 0.045
cellular nitrogen compound catabolic process GO:0044270 165 0.044
protein phosphorylation GO:0006468 169 0.044
purine nucleoside catabolic process GO:0006152 112 0.044
establishment of localization in cell GO:0051649 402 0.043
purine ribonucleotide metabolic process GO:0009150 145 0.042
ribonucleoside triphosphate catabolic process GO:0009203 108 0.041
negative regulation of transcription dna templated GO:0045892 237 0.040
chromosome organization GO:0051276 360 0.040
Human
nuclear dna replication GO:0033260 1 0.040
negative regulation of nucleic acid templated transcription GO:1903507 240 0.039
peptidyl amino acid modification GO:0018193 105 0.039
ribonucleoside monophosphate catabolic process GO:0009158 39 0.039
cellular response to organic substance GO:0071310 132 0.038
enzyme linked receptor protein signaling pathway GO:0007167 179 0.037
positive regulation of response to stimulus GO:0048584 323 0.037
carbohydrate derivative metabolic process GO:1901135 217 0.037
dna amplification GO:0006277 11 0.037
dna conformation change GO:0071103 105 0.036
nucleoside phosphate catabolic process GO:1901292 110 0.034
cellular response to light stimulus GO:0071482 37 0.034
chromosome separation GO:0051304 42 0.033
meiotic cell cycle GO:0051321 171 0.033
negative regulation of cellular biosynthetic process GO:0031327 277 0.033
response to alkaloid GO:0043279 26 0.032
positive regulation of proteolysis GO:0045862 52 0.032
organonitrogen compound catabolic process GO:1901565 128 0.032
organonitrogen compound metabolic process GO:1901564 318 0.032
cellular macromolecule localization GO:0070727 220 0.031
regulation of catabolic process GO:0009894 170 0.031
negative regulation of gene expression GO:0010629 387 0.031
nucleoside triphosphate metabolic process GO:0009141 120 0.030
macromolecule catabolic process GO:0009057 161 0.030
purine containing compound metabolic process GO:0072521 155 0.029
eggshell chorion gene amplification GO:0007307 9 0.028
positive regulation of signal transduction GO:0009967 223 0.028
glycosyl compound metabolic process GO:1901657 127 0.028
positive regulation of nucleic acid templated transcription GO:1903508 266 0.028
nucleoside catabolic process GO:0009164 112 0.028
mrna splicing via spliceosome GO:0000398 73 0.027
regulation of neurogenesis GO:0050767 158 0.027
carbohydrate derivative catabolic process GO:1901136 118 0.027
positive regulation of apoptotic process GO:0043065 47 0.026
nucleoside phosphate metabolic process GO:0006753 162 0.026
cellular macromolecule catabolic process GO:0044265 136 0.026
organophosphate metabolic process GO:0019637 195 0.026
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.025
body morphogenesis GO:0010171 2 0.025
nucleoside monophosphate metabolic process GO:0009123 52 0.025
response to caffeine GO:0031000 12 0.025
purine nucleotide metabolic process GO:0006163 146 0.025
negative regulation of neural precursor cell proliferation GO:2000178 27 0.024
regionalization GO:0003002 416 0.024
negative regulation of peptidoglycan recognition protein signaling pathway GO:0061060 3 0.024
regulation of phosphorus metabolic process GO:0051174 210 0.024
purine nucleoside metabolic process GO:0042278 127 0.024
karyosome formation GO:0030717 22 0.024
purine ribonucleoside metabolic process GO:0046128 127 0.024
carboxylic acid metabolic process GO:0019752 92 0.023
regulation of response to stress GO:0080134 200 0.023
protein catabolic process GO:0030163 101 0.023
endocytosis GO:0006897 310 0.023
negative regulation of dna recombination GO:0045910 2 0.023
nucleobase containing small molecule metabolic process GO:0055086 174 0.022
response to organic cyclic compound GO:0014070 89 0.022
negative regulation of cell cycle process GO:0010948 109 0.022
positive regulation of hydrolase activity GO:0051345 78 0.022
negative regulation of cell division GO:0051782 17 0.022
replication fork processing GO:0031297 0 0.022
female meiotic division GO:0007143 70 0.022
purine ribonucleotide catabolic process GO:0009154 109 0.022
nucleotide metabolic process GO:0009117 161 0.022
cellular response to gamma radiation GO:0071480 10 0.022
intracellular transport GO:0046907 228 0.022
negative regulation of programmed cell death GO:0043069 72 0.021
regulation of kinase activity GO:0043549 53 0.021
response to endogenous stimulus GO:0009719 119 0.021
centrosome duplication GO:0051298 121 0.021
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.021
purine nucleoside triphosphate metabolic process GO:0009144 119 0.021
imaginal disc derived wing morphogenesis GO:0007476 337 0.021
multicellular organismal aging GO:0010259 140 0.021
dorsal ventral pattern formation GO:0009953 133 0.021
purine containing compound catabolic process GO:0072523 112 0.020
regulation of phosphorylation GO:0042325 147 0.020
cell motility GO:0048870 251 0.020
tube development GO:0035295 244 0.020
central nervous system development GO:0007417 201 0.020
intracellular signal transduction GO:0035556 300 0.020
regulation of phosphate metabolic process GO:0019220 210 0.020
connective tissue development GO:0061448 3 0.019
negative regulation of cellular metabolic process GO:0031324 382 0.019
mrna processing GO:0006397 104 0.019
cell type specific apoptotic process GO:0097285 38 0.019
ribonucleotide catabolic process GO:0009261 109 0.019
negative regulation of rna biosynthetic process GO:1902679 240 0.019
mitotic nuclear division GO:0007067 213 0.019
positive regulation of catalytic activity GO:0043085 118 0.019
nucleoside metabolic process GO:0009116 127 0.018
organophosphate catabolic process GO:0046434 112 0.018
macromolecular complex assembly GO:0065003 256 0.018
meiotic cell cycle process GO:1903046 132 0.018
embryonic morphogenesis GO:0048598 206 0.018
response to ionizing radiation GO:0010212 32 0.018
purine nucleoside triphosphate catabolic process GO:0009146 108 0.018
positive regulation of cell communication GO:0010647 250 0.018
appendage morphogenesis GO:0035107 397 0.017
determination of adult lifespan GO:0008340 137 0.017
regulation of molecular function GO:0065009 217 0.017
cytoplasmic transport GO:0016482 130 0.017
regulation of catalytic activity GO:0050790 185 0.017
nucleotide catabolic process GO:0009166 109 0.017
purine ribonucleoside catabolic process GO:0046130 112 0.017
sensory perception GO:0007600 196 0.017
proteolysis GO:0006508 192 0.017
protein modification by small protein conjugation or removal GO:0070647 106 0.017
imaginal disc derived appendage development GO:0048737 399 0.017
purine nucleotide catabolic process GO:0006195 109 0.016
resolution of meiotic recombination intermediates GO:0000712 6 0.016
chromatin remodeling GO:0006338 72 0.016
cell aging GO:0007569 2 0.016
Human
regulation of cell development GO:0060284 215 0.016
chromosome segregation GO:0007059 157 0.016
regulation of nervous system development GO:0051960 248 0.016
negative regulation of cell proliferation GO:0008285 69 0.016
regulation of nuclear division GO:0051783 58 0.016
immune system development GO:0002520 57 0.015
positive regulation of nervous system development GO:0051962 69 0.015
dna packaging GO:0006323 91 0.015
regulation of rna splicing GO:0043484 69 0.015
positive regulation of cell differentiation GO:0045597 64 0.015
cellular response to chemical stimulus GO:0070887 199 0.015
response to oxygen containing compound GO:1901700 200 0.015
establishment of protein localization GO:0045184 163 0.015
mrna metabolic process GO:0016071 124 0.015
response to gamma radiation GO:0010332 17 0.015
protein maturation GO:0051604 71 0.015
chromatin organization GO:0006325 207 0.015
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.015
epidermis development GO:0008544 65 0.015
nucleoside monophosphate catabolic process GO:0009125 39 0.014
respiratory system development GO:0060541 213 0.014
regulation of cell differentiation GO:0045595 302 0.014
larval development GO:0002164 104 0.014
regulation of chromosome organization GO:0033044 64 0.014
dna catabolic process exonucleolytic GO:0000738 8 0.014
embryo development ending in birth or egg hatching GO:0009792 152 0.014
oxoacid metabolic process GO:0043436 103 0.014
regulation of peptidase activity GO:0052547 39 0.014
positive regulation of transport GO:0051050 92 0.014
multicellular organismal homeostasis GO:0048871 41 0.013
dendrite morphogenesis GO:0048813 199 0.013
reproductive behavior GO:0019098 122 0.013
regulation of transport GO:0051049 181 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
negative regulation of synapse assembly GO:0051964 39 0.013
regulation of cellular protein metabolic process GO:0032268 243 0.013
phosphorylation GO:0016310 294 0.013
wing disc morphogenesis GO:0007472 344 0.013
open tracheal system development GO:0007424 204 0.013
regulation of cellular ketone metabolic process GO:0010565 3 0.013
organic acid metabolic process GO:0006082 103 0.012
organic substance transport GO:0071702 257 0.012
response to purine containing compound GO:0014074 12 0.012
regulation of protein modification process GO:0031399 112 0.012
dendrite development GO:0016358 204 0.012
dna catabolic process GO:0006308 16 0.012
protein transport GO:0015031 155 0.012
single organism intracellular transport GO:1902582 207 0.012
tissue morphogenesis GO:0048729 297 0.012
cellular amino acid metabolic process GO:0006520 61 0.012
negative regulation of dna metabolic process GO:0051053 12 0.012
positive regulation of intracellular signal transduction GO:1902533 116 0.012
notch signaling pathway GO:0007219 120 0.011
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.011
cell fate determination GO:0001709 91 0.011
biological adhesion GO:0022610 138 0.011
cellular response to oxygen containing compound GO:1901701 79 0.011
cell migration GO:0016477 238 0.011
phagocytosis GO:0006909 215 0.011
regulation of protein metabolic process GO:0051246 256 0.011
peptidyl tyrosine modification GO:0018212 24 0.011
female meiosis chromosome segregation GO:0016321 33 0.011
anterior posterior pattern specification GO:0009952 136 0.011
gliogenesis GO:0042063 80 0.011
negative regulation of nervous system development GO:0051961 92 0.011
positive regulation of molecular function GO:0044093 136 0.011
regulation of dna replication GO:0006275 13 0.011
negative regulation of developmental process GO:0051093 201 0.011
regulation of establishment of protein localization GO:0070201 61 0.011
positive regulation of multi organism process GO:0043902 40 0.011
intra s dna damage checkpoint GO:0031573 2 0.011
negative regulation of response to stimulus GO:0048585 258 0.010
regulation of protein phosphorylation GO:0001932 64 0.010
positive regulation of dna metabolic process GO:0051054 12 0.010
negative regulation of organelle organization GO:0010639 56 0.010
protein processing GO:0016485 68 0.010
chorion containing eggshell formation GO:0007304 105 0.010
transcription from rna polymerase ii promoter GO:0006366 368 0.010
dna dependent dna replication maintenance of fidelity GO:0045005 0 0.010

CG5524 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
cancer DOID:162 0 0.103
disease of cellular proliferation DOID:14566 0 0.103
musculoskeletal system cancer DOID:0060100 0 0.034
organ system cancer DOID:0050686 0 0.034
thoracic cancer DOID:5093 0 0.030
disease of anatomical entity DOID:7 0 0.028
nervous system disease DOID:863 0 0.018
sensory system disease DOID:0050155 0 0.018
eye and adnexa disease DOID:1492 0 0.018