Drosophila melanogaster

43 known processes

CG5525 (Dmel_CG5525)

CG5525 gene product from transcript CG5525-RA

(Aliases: Tcp-1delta,Dmel\CG5525,Cct4)

CG5525 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
mitotic spindle organization GO:0007052 220 0.922
spindle organization GO:0007051 253 0.903
cytoplasmic microtubule organization GO:0031122 22 0.758
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.572
protein complex assembly GO:0006461 200 0.449
protein complex biogenesis GO:0070271 201 0.449
spindle assembly involved in mitosis GO:0090307 50 0.421
embryo development ending in birth or egg hatching GO:0009792 152 0.348
Worm
macromolecular complex assembly GO:0065003 256 0.340
spindle assembly GO:0051225 80 0.302
centrosome organization GO:0051297 163 0.284
chromosome organization GO:0051276 360 0.279
death GO:0016265 284 0.271
Worm
endocytosis GO:0006897 310 0.258
Worm
vesicle mediated transport GO:0016192 381 0.242
Worm
organelle fission GO:0048285 340 0.205
nuclear division GO:0000280 332 0.201
positive regulation of cellular biosynthetic process GO:0031328 316 0.199
programmed cell death GO:0012501 257 0.197
Worm
negative regulation of gene expression GO:0010629 387 0.190
tissue morphogenesis GO:0048729 297 0.186
larval development GO:0002164 104 0.179
Worm
small molecule metabolic process GO:0044281 305 0.171
cell recognition GO:0008037 102 0.164
Mouse
cell motility GO:0048870 251 0.156
carbohydrate derivative metabolic process GO:1901135 217 0.152
negative regulation of cellular biosynthetic process GO:0031327 277 0.152
cellular catabolic process GO:0044248 372 0.150
purine containing compound metabolic process GO:0072521 155 0.149
ribose phosphate metabolic process GO:0019693 145 0.149
microtubule organizing center organization GO:0031023 168 0.148
purine nucleoside triphosphate metabolic process GO:0009144 119 0.133
nucleotide catabolic process GO:0009166 109 0.133
cell death GO:0008219 279 0.132
Worm
apoptotic process GO:0006915 159 0.122
Worm
purine ribonucleotide metabolic process GO:0009150 145 0.117
centrosome cycle GO:0007098 137 0.112
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.105
nucleoside triphosphate metabolic process GO:0009141 120 0.103
mitotic nuclear division GO:0007067 213 0.100
negative regulation of cellular metabolic process GO:0031324 382 0.097
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.097
growth GO:0040007 359 0.097
centrosome duplication GO:0051298 121 0.096
positive regulation of macromolecule metabolic process GO:0010604 405 0.096
developmental growth GO:0048589 280 0.095
ribonucleoside metabolic process GO:0009119 127 0.091
positive regulation of gene expression GO:0010628 290 0.090
organophosphate metabolic process GO:0019637 195 0.089
translation GO:0006412 69 0.088
nucleoside triphosphate catabolic process GO:0009143 108 0.082
single fertilization GO:0007338 24 0.076
Mouse
purine ribonucleotide catabolic process GO:0009154 109 0.072
regulation of apoptotic process GO:0042981 130 0.067
regulation of phosphate metabolic process GO:0019220 210 0.062
cellular response to organic substance GO:0071310 132 0.058
nucleobase containing compound catabolic process GO:0034655 165 0.057
fertilization GO:0009566 26 0.057
Mouse
response to biotic stimulus GO:0009607 294 0.055
cellular response to chemical stimulus GO:0070887 199 0.054
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.054
cellular macromolecular complex assembly GO:0034622 153 0.052
ribonucleotide metabolic process GO:0009259 145 0.052
negative regulation of response to stimulus GO:0048585 258 0.052
developmental programmed cell death GO:0010623 138 0.052
nucleobase containing small molecule metabolic process GO:0055086 174 0.050
single organism catabolic process GO:0044712 228 0.049
positive regulation of phosphorus metabolic process GO:0010562 139 0.048
regulation of catabolic process GO:0009894 170 0.048
regulation of cellular protein metabolic process GO:0032268 243 0.048
purine nucleotide catabolic process GO:0006195 109 0.048
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.047
purine nucleoside triphosphate catabolic process GO:0009146 108 0.047
protein transport GO:0015031 155 0.047
organic cyclic compound catabolic process GO:1901361 168 0.046
organonitrogen compound catabolic process GO:1901565 128 0.046
chromatin organization GO:0006325 207 0.046
purine ribonucleoside monophosphate metabolic process GO:0009167 50 0.046
establishment of protein localization GO:0045184 163 0.045
glycosyl compound catabolic process GO:1901658 112 0.044
negative regulation of rna metabolic process GO:0051253 251 0.043
organic substance catabolic process GO:1901575 308 0.042
positive regulation of biosynthetic process GO:0009891 316 0.041
cellular macromolecule localization GO:0070727 220 0.040
organic acid metabolic process GO:0006082 103 0.040
response to decreased oxygen levels GO:0036293 58 0.039
Zebrafish
atp metabolic process GO:0046034 49 0.039
negative regulation of rna biosynthetic process GO:1902679 240 0.039
organonitrogen compound metabolic process GO:1901564 318 0.039
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.039
negative regulation of biosynthetic process GO:0009890 277 0.039
nucleoside metabolic process GO:0009116 127 0.038
protein modification process GO:0036211 438 0.037
ribonucleoside catabolic process GO:0042454 112 0.037
morphogenesis of an epithelium GO:0002009 276 0.036
proteolysis GO:0006508 192 0.036
purine nucleotide metabolic process GO:0006163 146 0.035
protein localization GO:0008104 284 0.035
tube morphogenesis GO:0035239 191 0.035
purine nucleoside catabolic process GO:0006152 112 0.034
response to organic substance GO:0010033 284 0.034
response to external biotic stimulus GO:0043207 293 0.033
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.033
catabolic process GO:0009056 409 0.032
sex differentiation GO:0007548 81 0.032
chromatin modification GO:0016568 147 0.032
response to hypoxia GO:0001666 53 0.031
Zebrafish
aging GO:0007568 143 0.031
Worm
regulation of translation GO:0006417 56 0.031
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.030
reproductive system development GO:0061458 74 0.030
purine containing compound catabolic process GO:0072523 112 0.030
intracellular signal transduction GO:0035556 300 0.030
cellular protein complex assembly GO:0043623 71 0.030
purine nucleoside monophosphate metabolic process GO:0009126 50 0.029
gland development GO:0048732 191 0.029
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.029
multicellular organismal aging GO:0010259 140 0.029
Worm
cell proliferation GO:0008283 299 0.029
positive regulation of protein metabolic process GO:0051247 128 0.029
cellular lipid metabolic process GO:0044255 83 0.028
phosphorylation GO:0016310 294 0.028
organelle assembly GO:0070925 198 0.028
eye development GO:0001654 323 0.027
aromatic compound catabolic process GO:0019439 166 0.026
defense response to other organism GO:0098542 225 0.026
negative regulation of nucleic acid templated transcription GO:1903507 240 0.026
phagocytosis GO:0006909 215 0.025
dendrite morphogenesis GO:0048813 199 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.025
negative regulation of cell death GO:0060548 81 0.025
positive regulation of multicellular organism growth GO:0040018 21 0.025
nucleoside catabolic process GO:0009164 112 0.025
camera type eye development GO:0043010 4 0.024
mitochondrion organization GO:0007005 65 0.024
regulation of developmental growth GO:0048638 174 0.024
organic substance transport GO:0071702 257 0.024
posttranscriptional regulation of gene expression GO:0010608 145 0.023
determination of adult lifespan GO:0008340 137 0.023
Worm
carbohydrate derivative catabolic process GO:1901136 118 0.023
development of primary sexual characteristics GO:0045137 50 0.023
gonad development GO:0008406 50 0.022
regulation of intracellular signal transduction GO:1902531 236 0.022
cellular response to decreased oxygen levels GO:0036294 30 0.022
nucleotide metabolic process GO:0009117 161 0.022
response to abiotic stimulus GO:0009628 341 0.021
Zebrafish
glycosyl compound metabolic process GO:1901657 127 0.021
axonogenesis GO:0007409 290 0.021
regulation of protein metabolic process GO:0051246 256 0.021
regulation of molecular function GO:0065009 217 0.021
localization of cell GO:0051674 257 0.021
reproductive structure development GO:0048608 74 0.021
response to other organism GO:0051707 293 0.021
regulation of nucleotide metabolic process GO:0006140 62 0.021
negative regulation of cell differentiation GO:0045596 143 0.021
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.021
ribonucleoprotein complex biogenesis GO:0022613 31 0.021
purine ribonucleoside metabolic process GO:0046128 127 0.021
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.020
purine ribonucleoside catabolic process GO:0046130 112 0.020
embryonic morphogenesis GO:0048598 206 0.020
regulation of cellular ketone metabolic process GO:0010565 3 0.020
regulation of response to stress GO:0080134 200 0.020
regulation of anatomical structure morphogenesis GO:0022603 242 0.020
regulation of catalytic activity GO:0050790 185 0.019
rna splicing via transesterification reactions GO:0000375 73 0.019
ribonucleoside triphosphate catabolic process GO:0009203 108 0.019
centriole replication GO:0007099 24 0.019
cellular amino acid metabolic process GO:0006520 61 0.019
purine nucleoside metabolic process GO:0042278 127 0.019
regulation of programmed cell death GO:0043067 152 0.019
chromatin remodeling GO:0006338 72 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
negative regulation of transcription dna templated GO:0045892 237 0.019
ribonucleoside triphosphate metabolic process GO:0009199 119 0.019
positive regulation of response to stimulus GO:0048584 323 0.018
positive regulation of signaling GO:0023056 243 0.018
immune system process GO:0002376 347 0.018
microtubule polymerization or depolymerization GO:0031109 39 0.017
positive regulation of catalytic activity GO:0043085 118 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
mapk cascade GO:0000165 107 0.017
homeostatic process GO:0042592 199 0.017
defense response to gram negative bacterium GO:0050829 94 0.017
protein dna complex subunit organization GO:0071824 86 0.017
mitotic spindle elongation GO:0000022 81 0.017
macromolecule catabolic process GO:0009057 161 0.017
endomembrane system organization GO:0010256 119 0.016
carboxylic acid metabolic process GO:0019752 92 0.016
gland morphogenesis GO:0022612 145 0.016
regulation of cell death GO:0010941 173 0.016
cellular component assembly involved in morphogenesis GO:0010927 151 0.016
positive regulation of signal transduction GO:0009967 223 0.016
ribonucleoside monophosphate metabolic process GO:0009161 51 0.016
positive regulation of cell death GO:0010942 69 0.016
nucleoside phosphate metabolic process GO:0006753 162 0.016
negative regulation of programmed cell death GO:0043069 72 0.016
wound healing GO:0042060 75 0.015
taxis GO:0042330 304 0.015
single organism biosynthetic process GO:0044711 206 0.015
cellular ketone metabolic process GO:0042180 24 0.015
epithelial cell development GO:0002064 274 0.015
regulation of phosphorylation GO:0042325 147 0.015
chemotaxis GO:0006935 249 0.015
establishment of protein localization to organelle GO:0072594 62 0.015
epithelial cell differentiation GO:0030855 322 0.015
cytoplasmic transport GO:0016482 130 0.015
regulation of purine nucleotide metabolic process GO:1900542 62 0.014
organophosphate catabolic process GO:0046434 112 0.014
regulation of rna splicing GO:0043484 69 0.014
positive regulation of organelle organization GO:0010638 65 0.014
dna metabolic process GO:0006259 227 0.014
defense response GO:0006952 300 0.014
tripartite regional subdivision GO:0007351 103 0.014
axon development GO:0061564 297 0.014
regulation of meiosis GO:0040020 3 0.013
response to extracellular stimulus GO:0009991 116 0.013
regulation of cell development GO:0060284 215 0.013
intermediate filament based process GO:0045103 1 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
signal transduction by phosphorylation GO:0023014 107 0.013
single organism behavior GO:0044708 391 0.013
cation transport GO:0006812 110 0.013
anatomical structure homeostasis GO:0060249 97 0.013
cell type specific apoptotic process GO:0097285 38 0.013
transcription from rna polymerase ii promoter GO:0006366 368 0.013
regulation of peptidase activity GO:0052547 39 0.012
muscle structure development GO:0061061 224 0.012
protein catabolic process GO:0030163 101 0.012
regulation of cellular response to stress GO:0080135 89 0.012
histone modification GO:0016570 106 0.012
autophagy GO:0006914 108 0.012
stress activated protein kinase signaling cascade GO:0031098 55 0.012
cardiovascular system development GO:0072358 82 0.012
protein targeting GO:0006605 64 0.012
regulation of cellular amino acid metabolic process GO:0006521 0 0.012
trna aminoacylation for protein translation GO:0006418 2 0.012
rna processing GO:0006396 147 0.012
axis specification GO:0009798 167 0.012
single organism cell adhesion GO:0098602 47 0.012
pole plasm rna localization GO:0007316 52 0.012
segmentation GO:0035282 207 0.011
heterocycle catabolic process GO:0046700 166 0.011
forebrain development GO:0030900 2 0.011
establishment of localization in cell GO:0051649 402 0.011
immune response GO:0006955 246 0.011
positive regulation of molecular function GO:0044093 136 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
protein processing GO:0016485 68 0.011
embryonic axis specification GO:0000578 107 0.011
photoreceptor cell differentiation GO:0046530 170 0.011
interspecies interaction between organisms GO:0044419 16 0.011
positive regulation of apoptotic process GO:0043065 47 0.010
intracellular transport GO:0046907 228 0.010
lipid metabolic process GO:0006629 121 0.010
dendrite development GO:0016358 204 0.010
regulation of immune response GO:0050776 118 0.010
regulation of protein catabolic process GO:0042176 55 0.010
positive regulation of cellular protein metabolic process GO:0032270 118 0.010

CG5525 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.021
disease of metabolism DOID:0014667 0 0.011