Drosophila melanogaster

50 known processes

MED30 (Dmel_CG17183)

Mediator complex subunit 30

(Aliases: dMED20,CG17183,Med20,Med30,Dmel\CG17183,dTRAP25,Trap25,med30,Med11/TRAP25)

MED30 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
transcription from rna polymerase ii promoter GO:0006366 368 0.340
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.165
Human
eye development GO:0001654 323 0.147
positive regulation of gene expression GO:0010628 290 0.115
Human
rna processing GO:0006396 147 0.109
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.103
Human
mrna metabolic process GO:0016071 124 0.094
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.094
positive regulation of biosynthetic process GO:0009891 316 0.091
Human
negative regulation of gene expression GO:0010629 387 0.080
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.077
macromolecule catabolic process GO:0009057 161 0.076
negative regulation of rna metabolic process GO:0051253 251 0.074
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.073
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.070
gene silencing by rna GO:0031047 57 0.059
protein complex biogenesis GO:0070271 201 0.055
posttranscriptional gene silencing by rna GO:0035194 45 0.054
organic cyclic compound catabolic process GO:1901361 168 0.054
cellular protein modification process GO:0006464 438 0.048
cell proliferation GO:0008283 299 0.048
cellular nitrogen compound catabolic process GO:0044270 165 0.048
negative regulation of rna biosynthetic process GO:1902679 240 0.047
compound eye development GO:0048749 307 0.047
negative regulation of biosynthetic process GO:0009890 277 0.047
posttranscriptional regulation of gene expression GO:0010608 145 0.046
positive regulation of cellular biosynthetic process GO:0031328 316 0.045
Human
body morphogenesis GO:0010171 2 0.044
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.040
regulation of translation GO:0006417 56 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.037
nucleobase containing compound catabolic process GO:0034655 165 0.037
regulation of cell cycle process GO:0010564 181 0.036
positive regulation of macromolecule metabolic process GO:0010604 405 0.036
Human
macromolecular complex assembly GO:0065003 256 0.036
positive regulation of nucleic acid templated transcription GO:1903508 266 0.034
Human
regulation of cell development GO:0060284 215 0.034
mrna catabolic process GO:0006402 33 0.033
mrna splicing via spliceosome GO:0000398 73 0.031
heterocycle catabolic process GO:0046700 166 0.030
positive regulation of rna metabolic process GO:0051254 271 0.030
Human
mitotic g2 m transition checkpoint GO:0044818 70 0.030
g2 dna damage checkpoint GO:0031572 69 0.029
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.029
protein modification process GO:0036211 438 0.028
nuclear transcribed mrna catabolic process GO:0000956 24 0.027
regionalization GO:0003002 416 0.027
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.026
Human
regulation of gene expression epigenetic GO:0040029 128 0.026
negative regulation of cellular biosynthetic process GO:0031327 277 0.026
regulation of cellular component biogenesis GO:0044087 201 0.026
negative regulation of multicellular organismal process GO:0051241 142 0.026
mrna processing GO:0006397 104 0.025
posttranscriptional gene silencing GO:0016441 46 0.025
larval development GO:0002164 104 0.025
negative regulation of mitotic cell cycle GO:0045930 109 0.025
catabolic process GO:0009056 409 0.024
organelle fission GO:0048285 340 0.024
negative regulation of nucleic acid templated transcription GO:1903507 240 0.024
negative regulation of developmental process GO:0051093 201 0.024
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.023
negative regulation of cellular metabolic process GO:0031324 382 0.023
rna interference GO:0016246 27 0.023
rna splicing GO:0008380 83 0.023
snrna 3 end processing GO:0034472 14 0.022
cellular catabolic process GO:0044248 372 0.021
organic substance catabolic process GO:1901575 308 0.021
open tracheal system development GO:0007424 204 0.021
camera type eye development GO:0043010 4 0.020
meiotic cell cycle GO:0051321 171 0.020
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.020
regulation of cell proliferation GO:0042127 163 0.020
cellular response to chemical stimulus GO:0070887 199 0.019
regulation of neurogenesis GO:0050767 158 0.019
cellular macromolecule catabolic process GO:0044265 136 0.019
regulation of catalytic activity GO:0050790 185 0.019
sensory organ morphogenesis GO:0090596 260 0.019
cell death GO:0008219 279 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.018
endocytosis GO:0006897 310 0.018
negative regulation of cell differentiation GO:0045596 143 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
stem cell proliferation GO:0072089 88 0.018
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.018
cellular macromolecular complex assembly GO:0034622 153 0.018
positive regulation of rna biosynthetic process GO:1902680 266 0.018
Human
nuclear division GO:0000280 332 0.017
negative regulation of signaling GO:0023057 219 0.017
phagocytosis GO:0006909 215 0.017
carbohydrate derivative metabolic process GO:1901135 217 0.017
regulation of cell differentiation GO:0045595 302 0.017
anterior posterior pattern specification GO:0009952 136 0.017
dna conformation change GO:0071103 105 0.017
negative regulation of transcription dna templated GO:0045892 237 0.017
dna templated transcription initiation GO:0006352 25 0.016
Human
mitotic dna integrity checkpoint GO:0044774 75 0.016
rna splicing via transesterification reactions GO:0000375 73 0.016
compound eye morphogenesis GO:0001745 249 0.016
regulation of cell cycle GO:0051726 291 0.016
dna integrity checkpoint GO:0031570 81 0.016
regulation of meiosis GO:0040020 3 0.015
regulation of immune system process GO:0002682 176 0.015
aromatic compound catabolic process GO:0019439 166 0.015
vesicle mediated transport GO:0016192 381 0.014
mitotic nuclear division GO:0007067 213 0.014
regulation of cell cycle phase transition GO:1901987 130 0.014
negative regulation of growth GO:0045926 84 0.014
establishment of localization in cell GO:0051649 402 0.014
negative regulation of cell cycle GO:0045786 116 0.014
regulation of multicellular organismal development GO:2000026 414 0.014
regulation of apoptotic process GO:0042981 130 0.014
positive regulation of transcription dna templated GO:0045893 266 0.013
Human
morphogenesis of an epithelium GO:0002009 276 0.013
negative regulation of cell cycle phase transition GO:1901988 103 0.013
small molecule metabolic process GO:0044281 305 0.013
nucleotide metabolic process GO:0009117 161 0.013
protein complex disassembly GO:0043241 36 0.013
regulation of mitotic cell cycle phase transition GO:1901990 130 0.013
response to biotic stimulus GO:0009607 294 0.013
protein complex assembly GO:0006461 200 0.013
regulation of multi organism process GO:0043900 131 0.013
phosphorylation GO:0016310 294 0.012
translation GO:0006412 69 0.012
oxoacid metabolic process GO:0043436 103 0.012
tissue morphogenesis GO:0048729 297 0.012
response to oxidative stress GO:0006979 86 0.012
actin filament organization GO:0007015 126 0.012
cellular protein complex assembly GO:0043623 71 0.012
regulation of nervous system development GO:0051960 248 0.012
purine containing compound metabolic process GO:0072521 155 0.012
regulation of gene silencing GO:0060968 63 0.011
death GO:0016265 284 0.011
cell division GO:0051301 248 0.011
chromosome condensation GO:0030261 41 0.011
organonitrogen compound metabolic process GO:1901564 318 0.011
macromolecular complex disassembly GO:0032984 37 0.011
regulation of heterochromatin assembly GO:0031445 8 0.011
cellular component disassembly GO:0022411 46 0.011
cell cycle checkpoint GO:0000075 95 0.011
eye photoreceptor cell differentiation GO:0001754 145 0.011
cell fate determination GO:0001709 91 0.011
programmed cell death GO:0012501 257 0.011
gene silencing GO:0016458 138 0.011
negative regulation of neural precursor cell proliferation GO:2000178 27 0.011
cellular respiration GO:0045333 26 0.011
mitotic dna damage checkpoint GO:0044773 74 0.010
response to oxygen containing compound GO:1901700 200 0.010
stem cell differentiation GO:0048863 117 0.010
regulation of programmed cell death GO:0043067 152 0.010
compound eye photoreceptor cell differentiation GO:0001751 140 0.010
trna transcription from rna polymerase iii promoter GO:0042797 1 0.010
negative regulation of nervous system development GO:0051961 92 0.010
nucleoside phosphate metabolic process GO:0006753 162 0.010

MED30 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.035
nervous system disease DOID:863 0 0.035
central nervous system disease DOID:331 0 0.011
neurodegenerative disease DOID:1289 0 0.010