Drosophila melanogaster

78 known processes

frc (Dmel_CG3874)

fringe connection

(Aliases: FRC,dFRC,l(3)S070006,UST74C,Dmel\CG3874,UDP-GlcNAc/UDP-GlcUA,anon-WO0172774.5,anon-WO0172774.7,l(3)10098,ust74C,l(3)L6750,CG3874,l(3)00073,l(3)j2E3,l(3)02619)

frc biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
embryonic morphogenesis GO:0048598 206 0.973
tube development GO:0035295 244 0.947
eye development GO:0001654 323 0.884
compound eye development GO:0048749 307 0.883
imaginal disc derived wing hair organization GO:0035317 45 0.866
tissue morphogenesis GO:0048729 297 0.846
Worm
imaginal disc derived appendage morphogenesis GO:0035114 395 0.836
morphogenesis of a polarized epithelium GO:0001738 93 0.819
digestive system development GO:0055123 149 0.815
axon guidance GO:0007411 233 0.795
tube morphogenesis GO:0035239 191 0.782
digestive tract development GO:0048565 149 0.751
formation of primary germ layer GO:0001704 24 0.737
gastrulation GO:0007369 70 0.730
establishment of tissue polarity GO:0007164 87 0.724
regionalization GO:0003002 416 0.719
cell motility GO:0048870 251 0.700
taxis GO:0042330 304 0.685
cell junction assembly GO:0034329 42 0.661
imaginal disc derived wing morphogenesis GO:0007476 337 0.647
wing disc morphogenesis GO:0007472 344 0.592
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.587
sensory organ morphogenesis GO:0090596 260 0.561
regulation of cell proliferation GO:0042127 163 0.554
non sensory hair organization GO:0035316 47 0.529
sensory perception GO:0007600 196 0.514
embryonic development via the syncytial blastoderm GO:0001700 148 0.504
sensory perception of sound GO:0007605 56 0.485
embryo development ending in birth or egg hatching GO:0009792 152 0.484
Mouse Worm
establishment of planar polarity GO:0001736 87 0.478
cell migration GO:0016477 238 0.471
enzyme linked receptor protein signaling pathway GO:0007167 179 0.459
sensory perception of mechanical stimulus GO:0050954 72 0.453
establishment or maintenance of apical basal cell polarity GO:0035088 34 0.453
mesoderm development GO:0007498 78 0.417
appendage morphogenesis GO:0035107 397 0.411
establishment of imaginal disc derived wing hair orientation GO:0001737 24 0.395
establishment or maintenance of bipolar cell polarity GO:0061245 34 0.390
carbohydrate derivative metabolic process GO:1901135 217 0.387
Mouse
imaginal disc derived leg morphogenesis GO:0007480 80 0.365
single organism cellular localization GO:1902580 180 0.364
regulation of multicellular organismal development GO:2000026 414 0.351
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.346
regulation of cell cycle GO:0051726 291 0.335
transcription from rna polymerase ii promoter GO:0006366 368 0.332
eye morphogenesis GO:0048592 260 0.325
protein modification process GO:0036211 438 0.325
regulation of cellular catabolic process GO:0031329 157 0.324
positive regulation of rna metabolic process GO:0051254 271 0.324
respiratory system development GO:0060541 213 0.323
regulation of anatomical structure morphogenesis GO:0022603 242 0.322
cell death GO:0008219 279 0.295
cell proliferation GO:0008283 299 0.294
digestive tract morphogenesis GO:0048546 127 0.294
establishment of localization in cell GO:0051649 402 0.291
developmental pigmentation GO:0048066 68 0.287
compound eye morphogenesis GO:0001745 249 0.286
positive regulation of transcription dna templated GO:0045893 266 0.281
forebrain development GO:0030900 2 0.275
appendage development GO:0048736 401 0.273
mesoderm morphogenesis GO:0048332 22 0.271
multi organism behavior GO:0051705 175 0.269
Worm
head development GO:0060322 135 0.266
cellular protein localization GO:0034613 160 0.266
axon development GO:0061564 297 0.255
localization of cell GO:0051674 257 0.254
hair cell differentiation GO:0035315 47 0.247
embryonic organ development GO:0048568 50 0.247
periodic partitioning GO:0007365 29 0.246
imaginal disc derived appendage development GO:0048737 399 0.244
larval development GO:0002164 104 0.243
Worm
positive regulation of rna biosynthetic process GO:1902680 266 0.240
regulation of molecular function GO:0065009 217 0.237
neurological system process GO:0050877 358 0.237
small molecule metabolic process GO:0044281 305 0.236
Mouse
asymmetric protein localization involved in cell fate determination GO:0045167 9 0.224
chemotaxis GO:0006935 249 0.221
central nervous system development GO:0007417 201 0.221
cellular polysaccharide metabolic process GO:0044264 11 0.219
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.212
intracellular signal transduction GO:0035556 300 0.211
glycosyl compound metabolic process GO:1901657 127 0.209
nuclear division GO:0000280 332 0.193
mesoderm formation GO:0001707 21 0.193
organonitrogen compound metabolic process GO:1901564 318 0.192
Mouse
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.189
gastrulation with mouth forming first GO:0001703 36 0.185
body morphogenesis GO:0010171 2 0.179
blastoderm segmentation GO:0007350 159 0.176
nucleoside phosphate catabolic process GO:1901292 110 0.174
anterior posterior pattern specification GO:0009952 136 0.173
regulation of cytoskeleton organization GO:0051493 89 0.173
ras protein signal transduction GO:0007265 88 0.168
open tracheal system development GO:0007424 204 0.168
regulation of catabolic process GO:0009894 170 0.165
neuron projection guidance GO:0097485 241 0.165
regulation of neurogenesis GO:0050767 158 0.164
imaginal disc derived wing vein morphogenesis GO:0008586 44 0.164
positive regulation of nucleic acid templated transcription GO:1903508 266 0.161
ameboidal type cell migration GO:0001667 151 0.161
cellular catabolic process GO:0044248 372 0.161
epithelial cell differentiation GO:0030855 322 0.161
segmentation GO:0035282 207 0.157
single organism behavior GO:0044708 391 0.156
organic substance catabolic process GO:1901575 308 0.156
endocytosis GO:0006897 310 0.155
non canonical wnt signaling pathway GO:0035567 8 0.155
reproductive structure development GO:0048608 74 0.152
ion transmembrane transport GO:0034220 122 0.149
catabolic process GO:0009056 409 0.147
positive regulation of phosphate metabolic process GO:0045937 139 0.146
protein localization GO:0008104 284 0.146
protein targeting GO:0006605 64 0.145
establishment of protein localization GO:0045184 163 0.144
cell migration involved in gastrulation GO:0042074 9 0.142
cellular macromolecule localization GO:0070727 220 0.138
oxoacid metabolic process GO:0043436 103 0.133
Mouse
establishment or maintenance of monopolar cell polarity GO:0061339 15 0.132
compound eye photoreceptor cell differentiation GO:0001751 140 0.130
embryonic pattern specification GO:0009880 174 0.130
axonogenesis GO:0007409 290 0.127
response to growth factor GO:0070848 31 0.126
regulation of phosphate metabolic process GO:0019220 210 0.126
regulation of protein localization GO:0032880 76 0.122
intracellular protein transport GO:0006886 104 0.121
regulation of protein modification process GO:0031399 112 0.121
establishment or maintenance of epithelial cell apical basal polarity GO:0045197 24 0.118
organic substance transport GO:0071702 257 0.118
purine nucleoside triphosphate metabolic process GO:0009144 119 0.114
imaginal disc derived wing margin morphogenesis GO:0008587 41 0.114
synaptic transmission GO:0007268 288 0.113
morphogenesis of an epithelium GO:0002009 276 0.113
Worm
regulation of ras protein signal transduction GO:0046578 93 0.113
regulation of programmed cell death GO:0043067 152 0.113
response to oxygen containing compound GO:1901700 200 0.112
neuromuscular junction development GO:0007528 149 0.112
response to organic substance GO:0010033 284 0.111
post embryonic appendage morphogenesis GO:0035120 385 0.111
leg disc morphogenesis GO:0007478 80 0.111
regulation of microtubule based process GO:0032886 49 0.111
epithelial cell migration GO:0010631 148 0.110
mesodermal cell migration GO:0008078 7 0.109
establishment of monopolar cell polarity GO:0061162 15 0.107
positive regulation of nucleoside metabolic process GO:0045979 47 0.106
establishment of organelle localization GO:0051656 122 0.105
positive regulation of catalytic activity GO:0043085 118 0.105
cellular protein modification process GO:0006464 438 0.105
camera type eye morphogenesis GO:0048593 2 0.105
establishment or maintenance of cell polarity GO:0007163 167 0.104
developmental growth GO:0048589 280 0.104
axis specification GO:0009798 167 0.102
regulation of localization GO:0032879 275 0.102
purine nucleoside catabolic process GO:0006152 112 0.102
positive regulation of gtp catabolic process GO:0033126 43 0.101
guanosine containing compound catabolic process GO:1901069 74 0.101
cellular response to dna damage stimulus GO:0006974 223 0.101
developmental maturation GO:0021700 172 0.101
single organism membrane organization GO:0044802 93 0.100
peripheral nervous system development GO:0007422 52 0.100
regulation of nervous system development GO:0051960 248 0.097
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.097
developmental programmed cell death GO:0010623 138 0.097
sex differentiation GO:0007548 81 0.096
regulation of epithelial cell proliferation GO:0050678 4 0.095
cell division GO:0051301 248 0.094
regulation of organ morphogenesis GO:2000027 78 0.093
retina development in camera type eye GO:0060041 4 0.093
leg disc development GO:0035218 92 0.092
reproductive system development GO:0061458 74 0.092
chondroitin sulfate metabolic process GO:0030204 2 0.092
Mouse
embryonic digestive tract development GO:0048566 5 0.091
positive regulation of molecular function GO:0044093 136 0.091
establishment of protein localization to organelle GO:0072594 62 0.090
single organism nuclear import GO:1902593 51 0.090
establishment or maintenance of microtubule cytoskeleton polarity GO:0030951 41 0.089
camera type eye development GO:0043010 4 0.088
imaginal disc derived leg joint morphogenesis GO:0016348 15 0.088
single organism catabolic process GO:0044712 228 0.088
establishment of epithelial cell apical basal polarity GO:0045198 10 0.087
dorsal closure GO:0007391 79 0.086
glycosyl compound catabolic process GO:1901658 112 0.086
response to endogenous stimulus GO:0009719 119 0.085
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.084
cellular response to fibroblast growth factor stimulus GO:0044344 10 0.084
neural precursor cell proliferation GO:0061351 75 0.084
response to fibroblast growth factor GO:0071774 10 0.083
epidermal cell differentiation GO:0009913 51 0.083
negative regulation of cell cycle GO:0045786 116 0.082
ribonucleotide metabolic process GO:0009259 145 0.082
endoderm formation GO:0001706 3 0.080
adult behavior GO:0030534 137 0.080
notch signaling pathway GO:0007219 120 0.080
positive regulation of cellular catabolic process GO:0031331 95 0.080
regulation of phosphorus metabolic process GO:0051174 210 0.080
positive regulation of nucleotide catabolic process GO:0030813 46 0.079
protein transport GO:0015031 155 0.079
germ band extension GO:0007377 11 0.079
dorsal ventral pattern formation GO:0009953 133 0.078
regulation of developmental pigmentation GO:0048070 24 0.077
regulation of cell development GO:0060284 215 0.076
glial cell differentiation GO:0010001 35 0.076
lipid metabolic process GO:0006629 121 0.076
regulation of apoptotic signaling pathway GO:2001233 10 0.076
nucleoside metabolic process GO:0009116 127 0.075
brain development GO:0007420 120 0.075
heparan sulfate proteoglycan biosynthetic process polysaccharide chain biosynthetic process GO:0015014 5 0.074
positive regulation of cellular component organization GO:0051130 156 0.074
imaginal disc derived wing vein specification GO:0007474 48 0.073
purine ribonucleoside metabolic process GO:0046128 127 0.073
epithelial tube morphogenesis GO:0060562 88 0.073
ion transport GO:0006811 145 0.073
asymmetric stem cell division GO:0098722 49 0.073
nucleobase containing compound catabolic process GO:0034655 165 0.072
kidney development GO:0001822 3 0.072
skin development GO:0043588 65 0.072
ribonucleoside triphosphate catabolic process GO:0009203 108 0.072
mesenchymal cell differentiation GO:0048762 1 0.071
establishment of ommatidial planar polarity GO:0042067 49 0.071
cell maturation GO:0048469 144 0.071
guanosine containing compound metabolic process GO:1901068 74 0.071
lipid localization GO:0010876 54 0.069
regulation of cell shape GO:0008360 113 0.068
compound eye photoreceptor fate commitment GO:0001752 36 0.068
organonitrogen compound catabolic process GO:1901565 128 0.068
endodermal cell fate commitment GO:0001711 3 0.067
negative regulation of biosynthetic process GO:0009890 277 0.065
cuticle development GO:0042335 86 0.065
maintenance of apical basal cell polarity GO:0035090 8 0.064
nuclear import GO:0051170 51 0.064
gastrulation involving germ band extension GO:0010004 36 0.064
carbohydrate derivative catabolic process GO:1901136 118 0.063
negative regulation of response to stimulus GO:0048585 258 0.063
embryonic digestive tract morphogenesis GO:0048557 4 0.063
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.062
negative regulation of epithelial cell proliferation GO:0050680 4 0.062
vesicle mediated transport GO:0016192 381 0.061
wnt signaling pathway GO:0016055 98 0.061
retina morphogenesis in camera type eye GO:0060042 2 0.061
regulation of cell division GO:0051302 72 0.061
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.060
growth GO:0040007 359 0.059
nucleotide metabolic process GO:0009117 161 0.059
glycoprotein metabolic process GO:0009100 41 0.059
Mouse
cellular response to organic substance GO:0071310 132 0.059
purine containing compound metabolic process GO:0072521 155 0.058
positive regulation of developmental process GO:0051094 143 0.058
regulation of microtubule cytoskeleton organization GO:0070507 41 0.058
neuroblast proliferation GO:0007405 74 0.057
cellular response to growth factor stimulus GO:0071363 30 0.056
programmed cell death GO:0012501 257 0.056
response to abiotic stimulus GO:0009628 341 0.056
mitotic nuclear division GO:0007067 213 0.055
regulation of small gtpase mediated signal transduction GO:0051056 93 0.055
regulation of nucleotide catabolic process GO:0030811 48 0.055
regulation of establishment of planar polarity GO:0090175 22 0.055
establishment or maintenance of cytoskeleton polarity GO:0030952 44 0.055
negative regulation of rna metabolic process GO:0051253 251 0.054
plasma membrane organization GO:0007009 26 0.054
apoptotic process GO:0006915 159 0.053
response to radiation GO:0009314 155 0.053
cellular lipid metabolic process GO:0044255 83 0.053
embryonic foregut morphogenesis GO:0048617 3 0.052
positive regulation of phosphorus metabolic process GO:0010562 139 0.052
stem cell differentiation GO:0048863 117 0.052
positive regulation of cell development GO:0010720 61 0.051
ribonucleoside catabolic process GO:0042454 112 0.050
cell junction organization GO:0034330 57 0.050
positive regulation of protein metabolic process GO:0051247 128 0.049
gtp catabolic process GO:0006184 72 0.049
regulation of muscle organ development GO:0048634 13 0.049
regulation of cellular localization GO:0060341 136 0.049
cardiovascular system development GO:0072358 82 0.048
positive regulation of response to stimulus GO:0048584 323 0.048
regulation of cell death GO:0010941 173 0.048
small gtpase mediated signal transduction GO:0007264 88 0.048
protein localization to nucleus GO:0034504 55 0.048
regulation of intracellular signal transduction GO:1902531 236 0.047
protein import GO:0017038 55 0.047
positive regulation of cellular biosynthetic process GO:0031328 316 0.046
regulation of notch signaling pathway GO:0008593 100 0.046
pigmentation GO:0043473 75 0.046
mushroom body development GO:0016319 70 0.045
regulation of transport GO:0051049 181 0.045
cell growth GO:0016049 108 0.045
epithelial cell morphogenesis GO:0003382 25 0.045
gliogenesis GO:0042063 80 0.045
chitin based cuticle development GO:0040003 49 0.044
centrosome organization GO:0051297 163 0.044
oocyte construction GO:0007308 112 0.044
epithelial cell development GO:0002064 274 0.044
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.044
regulation of cell differentiation GO:0045595 302 0.043
intracellular transport GO:0046907 228 0.043
epithelial cell proliferation GO:0050673 15 0.043
epidermis development GO:0008544 65 0.043
apical constriction GO:0003383 18 0.043
negative regulation of notch signaling pathway GO:0045746 41 0.042
cellular response to chemical stimulus GO:0070887 199 0.042
protein import into nucleus GO:0006606 51 0.042
apical constriction involved in gastrulation GO:0003384 7 0.042
nucleoside triphosphate catabolic process GO:0009143 108 0.042
ribonucleotide catabolic process GO:0009261 109 0.042
muscle structure development GO:0061061 224 0.041
purine nucleoside triphosphate catabolic process GO:0009146 108 0.041
photoreceptor cell fate commitment GO:0046552 41 0.041
telencephalon development GO:0021537 2 0.041
cellular amine metabolic process GO:0044106 12 0.041
establishment of spindle localization GO:0051293 22 0.041
negative regulation of growth GO:0045926 84 0.040
neuron fate commitment GO:0048663 50 0.040
immune system process GO:0002376 347 0.040
negative regulation of cellular metabolic process GO:0031324 382 0.040
regulation of apoptotic process GO:0042981 130 0.040
gonad development GO:0008406 50 0.040
single organismal cell cell adhesion GO:0016337 45 0.039
microtubule cytoskeleton organization involved in mitosis GO:1902850 52 0.039
establishment of cell polarity GO:0030010 40 0.039
negative regulation of multicellular organismal process GO:0051241 142 0.039
multi organism reproductive behavior GO:0044705 121 0.039
Worm
mesenchymal cell development GO:0014031 1 0.038
eye photoreceptor cell fate commitment GO:0042706 37 0.038
cellular nitrogen compound catabolic process GO:0044270 165 0.038
regulation of protein transport GO:0051223 57 0.038
regulation of cellular response to stress GO:0080135 89 0.038
maintenance of cell polarity GO:0030011 18 0.038
nucleotide catabolic process GO:0009166 109 0.038
cardioblast cell fate specification GO:0042685 9 0.038
development of primary sexual characteristics GO:0045137 50 0.037
negative regulation of developmental process GO:0051093 201 0.037
regulation of cell morphogenesis GO:0022604 163 0.037
cell fate specification GO:0001708 71 0.037
positive regulation of hydrolase activity GO:0051345 78 0.037
cytoplasmic transport GO:0016482 130 0.037
negative regulation of programmed cell death GO:0043069 72 0.037
trachea development GO:0060438 29 0.036
glycoprotein biosynthetic process GO:0009101 41 0.036
Mouse
regulation of establishment of protein localization GO:0070201 61 0.036
purine ribonucleoside catabolic process GO:0046130 112 0.036
cation transport GO:0006812 110 0.036
regulation of intracellular transport GO:0032386 64 0.035
amine metabolic process GO:0009308 12 0.035
regulation of embryonic development GO:0045995 68 0.035
phosphorylation GO:0016310 294 0.035
endodermal cell differentiation GO:0035987 3 0.035
regulation of organelle organization GO:0033043 196 0.035
nucleoside triphosphate metabolic process GO:0009141 120 0.034
nucleobase containing small molecule metabolic process GO:0055086 174 0.034
imaginal disc pattern formation GO:0007447 91 0.034
protein targeting to nucleus GO:0044744 51 0.034
regulation of intracellular protein transport GO:0033157 46 0.034
spindle organization GO:0007051 253 0.033
imaginal disc derived leg segmentation GO:0036011 26 0.033
actin cytoskeleton organization GO:0030036 206 0.033
proteasomal protein catabolic process GO:0010498 59 0.033
positive regulation of nucleotide metabolic process GO:0045981 55 0.033
immune system development GO:0002520 57 0.033
regulation of mitotic cell cycle GO:0007346 190 0.033
carbohydrate derivative biosynthetic process GO:1901137 85 0.032
Mouse
septate junction assembly GO:0019991 26 0.032
ribonucleoside metabolic process GO:0009119 127 0.032
nucleocytoplasmic transport GO:0006913 72 0.031
cellular amino acid metabolic process GO:0006520 61 0.031
regulation of catalytic activity GO:0050790 185 0.031
cell adhesion GO:0007155 136 0.031
male gonad development GO:0008584 9 0.031
positive regulation of gtpase activity GO:0043547 43 0.031
histone modification GO:0016570 106 0.030
purine nucleotide catabolic process GO:0006195 109 0.030
glial cell development GO:0021782 27 0.030
cellular response to endogenous stimulus GO:0071495 80 0.030
regulation of membrane potential GO:0042391 35 0.030
actin filament based process GO:0030029 220 0.029
negative regulation of rna biosynthetic process GO:1902679 240 0.029
extracellular matrix organization GO:0030198 32 0.029
unidimensional cell growth GO:0009826 15 0.029
endomembrane system organization GO:0010256 119 0.029
establishment or maintenance of polarity of follicular epithelium GO:0016334 26 0.029
muscle organ development GO:0007517 127 0.029
limb development GO:0060173 1 0.028
gtp metabolic process GO:0046039 72 0.028
cell cell junction organization GO:0045216 55 0.028
hematopoietic or lymphoid organ development GO:0048534 57 0.028
cell elongation involved in imaginal disc derived wing morphogenesis GO:0090254 5 0.028
positive regulation of protein transport GO:0051222 37 0.028
stem cell division GO:0017145 69 0.028
positive regulation of purine nucleotide catabolic process GO:0033123 46 0.028
developmental growth involved in morphogenesis GO:0060560 65 0.028
fibroblast growth factor receptor signaling pathway GO:0008543 10 0.027
regulation of ras gtpase activity GO:0032318 38 0.027
synapse assembly GO:0007416 143 0.027
synaptic growth at neuromuscular junction GO:0051124 119 0.027
regulation of cellular protein metabolic process GO:0032268 243 0.027
organophosphate biosynthetic process GO:0090407 46 0.027
male gamete generation GO:0048232 201 0.027
regulation of cell cycle process GO:0010564 181 0.026
dorsal ventral axis specification GO:0009950 66 0.026
establishment of mitotic spindle localization GO:0040001 17 0.026
positive regulation of signaling GO:0023056 243 0.026
convergent extension GO:0060026 2 0.026
wing disc pattern formation GO:0035222 66 0.026
sulfur compound metabolic process GO:0006790 59 0.026
Mouse
positive regulation of transport GO:0051050 92 0.026
negative regulation of cellular component organization GO:0051129 108 0.026
regulation of cellular amine metabolic process GO:0033238 3 0.026
purine ribonucleotide catabolic process GO:0009154 109 0.026
cuticle pattern formation GO:0035017 27 0.026
macromolecule catabolic process GO:0009057 161 0.025
regulation of kinase activity GO:0043549 53 0.025
negative regulation of synaptic growth at neuromuscular junction GO:0045886 39 0.025
positive regulation of cell differentiation GO:0045597 64 0.025
positive regulation of protein modification process GO:0031401 58 0.025
nucleoside catabolic process GO:0009164 112 0.025
establishment of protein localization to plasma membrane GO:0090002 9 0.025
morphogenesis of follicular epithelium GO:0016333 36 0.025
death GO:0016265 284 0.025
actin filament based movement GO:0030048 26 0.025
positive regulation of multicellular organismal process GO:0051240 143 0.024
purine nucleotide metabolic process GO:0006163 146 0.024
salivary gland development GO:0007431 162 0.024
gland morphogenesis GO:0022612 145 0.024
gland development GO:0048732 191 0.024
circulatory system development GO:0072359 82 0.024
determination of dorsal ventral asymmetry GO:0048262 3 0.024
oocyte differentiation GO:0009994 145 0.024
positive regulation of nervous system development GO:0051962 69 0.024
regulation of phosphorylation GO:0042325 147 0.024
nucleoside phosphate metabolic process GO:0006753 162 0.024
germ cell migration GO:0008354 43 0.024
wnt signaling pathway planar cell polarity pathway GO:0060071 6 0.023
exocrine system development GO:0035272 162 0.023
tissue homeostasis GO:0001894 36 0.023
organic hydroxy compound metabolic process GO:1901615 83 0.023
positive regulation of catabolic process GO:0009896 105 0.023
stem cell proliferation GO:0072089 88 0.023
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.023
organic cyclic compound catabolic process GO:1901361 168 0.023
heterocycle catabolic process GO:0046700 166 0.023
oocyte axis specification GO:0007309 108 0.023
establishment of protein localization to membrane GO:0090150 11 0.022
epithelial cell migration open tracheal system GO:0007427 32 0.022
chondroitin sulfate proteoglycan metabolic process GO:0050654 3 0.022
Mouse
regulation of purine nucleotide metabolic process GO:1900542 62 0.022
protein localization to organelle GO:0033365 82 0.022
enteroendocrine cell differentiation GO:0035883 1 0.022
renal system development GO:0072001 72 0.022
organelle fission GO:0048285 340 0.022
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.022
detection of external stimulus GO:0009581 66 0.022
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.022
organophosphate catabolic process GO:0046434 112 0.022
regulation of cell motility GO:2000145 23 0.022
limb morphogenesis GO:0035108 1 0.021
response to nitrogen compound GO:1901698 90 0.021
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.021
phenol containing compound metabolic process GO:0018958 57 0.021
epithelial cell cell adhesion GO:0090136 6 0.021
protein localization to membrane GO:0072657 19 0.021
mitotic spindle organization GO:0007052 220 0.021
development of primary male sexual characteristics GO:0046546 9 0.021
female gonad development GO:0008585 12 0.021
inorganic cation transmembrane transport GO:0098662 61 0.021
biological adhesion GO:0022610 138 0.020
peptidyl tyrosine modification GO:0018212 24 0.020
purine ribonucleotide metabolic process GO:0009150 145 0.020
skeletal muscle organ development GO:0060538 48 0.020
positive regulation of signal transduction GO:0009967 223 0.020
ribose phosphate metabolic process GO:0019693 145 0.020
cardioblast cell fate commitment GO:0042684 14 0.020
positive regulation of ras gtpase activity GO:0032320 36 0.020
instar larval development GO:0002168 55 0.020
negative regulation of cell proliferation GO:0008285 69 0.020
regulation of mapk cascade GO:0043408 92 0.020
genitalia development GO:0048806 26 0.020
neuronal stem cell division GO:0036445 35 0.019
tissue migration GO:0090130 155 0.019
photoreceptor cell differentiation GO:0046530 170 0.019
cell cell signaling involved in cell fate commitment GO:0045168 210 0.019
smoothened signaling pathway GO:0007224 49 0.019
cellular response to peptide GO:1901653 28 0.019
embryonic heart tube development GO:0035050 22 0.019
apical junction assembly GO:0043297 32 0.019
cell proliferation involved in imaginal disc derived wing morphogenesis GO:0090255 2 0.019
negative regulation of cell death GO:0060548 81 0.019
negative regulation of protein metabolic process GO:0051248 85 0.019
locomotory behavior GO:0007626 176 0.019
positive regulation of gene expression GO:0010628 290 0.018
intracellular mrna localization involved in anterior posterior axis specification GO:0060811 53 0.018
protein phosphorylation GO:0006468 169 0.018
negative regulation of cell fate commitment GO:0010454 17 0.018
heart development GO:0007507 82 0.018
convergent extension involved in gastrulation GO:0060027 2 0.018

frc disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.097
cancer DOID:162 0 0.041
disease of anatomical entity DOID:7 0 0.035
organ system cancer DOID:0050686 0 0.033
congenital heart disease DOID:1682 0 0.020
tetralogy of fallot DOID:6419 0 0.020
heart disease DOID:114 0 0.020
cardiovascular system disease DOID:1287 0 0.020