Drosophila melanogaster

159 known processes

lig (Dmel_CG8715)

lingerer

(Aliases: CG8715,Dmel\CG8715)

lig biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna splicing GO:0008380 83 0.612
negative regulation of rna biosynthetic process GO:1902679 240 0.485
negative regulation of cellular biosynthetic process GO:0031327 277 0.381
phosphorylation GO:0016310 294 0.377
positive regulation of transcription dna templated GO:0045893 266 0.375
actin filament based process GO:0030029 220 0.346
imaginal disc growth GO:0007446 37 0.341
response to biotic stimulus GO:0009607 294 0.340
cell migration GO:0016477 238 0.335
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.335
cell motility GO:0048870 251 0.331
purine nucleoside triphosphate catabolic process GO:0009146 108 0.329
positive regulation of nucleic acid templated transcription GO:1903508 266 0.307
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.297
programmed cell death GO:0012501 257 0.287
regulation of mitotic cell cycle GO:0007346 190 0.285
vesicle mediated transport GO:0016192 381 0.280
enzyme linked receptor protein signaling pathway GO:0007167 179 0.270
negative regulation of gene expression GO:0010629 387 0.265
localization of cell GO:0051674 257 0.243
muscle structure development GO:0061061 224 0.232
posttranscriptional regulation of gene expression GO:0010608 145 0.227
posttranscriptional gene silencing GO:0016441 46 0.225
mrna splicing via spliceosome GO:0000398 73 0.225
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.215
ribonucleoprotein complex assembly GO:0022618 23 0.203
regulation of developmental growth GO:0048638 174 0.195
regulation of growth GO:0040008 233 0.195
ribonucleoside catabolic process GO:0042454 112 0.189
posttranscriptional gene silencing by rna GO:0035194 45 0.187
response to other organism GO:0051707 293 0.177
gene silencing by mirna GO:0035195 22 0.176
negative regulation of signaling GO:0023057 219 0.174
endocytosis GO:0006897 310 0.162
regulation of cell morphogenesis GO:0022604 163 0.160
mitotic nuclear division GO:0007067 213 0.158
muscle cell differentiation GO:0042692 103 0.143
cytokinesis GO:0000910 90 0.142
establishment of localization in cell GO:0051649 402 0.138
photoreceptor cell differentiation GO:0046530 170 0.138
organelle assembly GO:0070925 198 0.135
negative regulation of cell communication GO:0010648 223 0.133
nucleobase containing compound catabolic process GO:0034655 165 0.133
purine ribonucleotide catabolic process GO:0009154 109 0.129
ribonucleoprotein complex subunit organization GO:0071826 28 0.123
rna processing GO:0006396 147 0.123
transcription from rna polymerase ii promoter GO:0006366 368 0.121
rna splicing via transesterification reactions GO:0000375 73 0.118
actin cytoskeleton organization GO:0030036 206 0.117
positive regulation of cellular component organization GO:0051130 156 0.113
regulation of programmed cell death GO:0043067 152 0.105
organophosphate metabolic process GO:0019637 195 0.105
cell death GO:0008219 279 0.105
ribonucleoside triphosphate catabolic process GO:0009203 108 0.104
negative regulation of transcription dna templated GO:0045892 237 0.103
nuclear transport GO:0051169 72 0.101
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.099
organelle localization GO:0051640 148 0.099
mrna processing GO:0006397 104 0.098
intracellular transport GO:0046907 228 0.095
regulation of cytoskeleton organization GO:0051493 89 0.093
carbohydrate derivative catabolic process GO:1901136 118 0.093
response to external biotic stimulus GO:0043207 293 0.092
regulation of apoptotic process GO:0042981 130 0.090
organelle fission GO:0048285 340 0.088
intracellular signal transduction GO:0035556 300 0.087
macromolecular complex assembly GO:0065003 256 0.087
regulation of protein stability GO:0031647 43 0.087
protein modification process GO:0036211 438 0.085
positive regulation of rna metabolic process GO:0051254 271 0.084
regulation of mrna processing GO:0050684 71 0.084
epithelial cell development GO:0002064 274 0.083
larval development GO:0002164 104 0.083
eye morphogenesis GO:0048592 260 0.083
cellular protein localization GO:0034613 160 0.080
regulation of cell cycle phase transition GO:1901987 130 0.080
ras protein signal transduction GO:0007265 88 0.079
nuclear division GO:0000280 332 0.078
cellular protein modification process GO:0006464 438 0.077
rac protein signal transduction GO:0016601 3 0.075
modification dependent macromolecule catabolic process GO:0043632 79 0.074
nucleoside phosphate metabolic process GO:0006753 162 0.073
response to bacterium GO:0009617 198 0.072
positive regulation of macromolecule metabolic process GO:0010604 405 0.072
cellular macromolecule localization GO:0070727 220 0.070
transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 116 0.070
regulation of transport GO:0051049 181 0.069
tissue morphogenesis GO:0048729 297 0.069
maintenance of location GO:0051235 73 0.066
protein localization GO:0008104 284 0.064
regulation of cell death GO:0010941 173 0.064
eye photoreceptor cell differentiation GO:0001754 145 0.064
glycosyl compound catabolic process GO:1901658 112 0.063
protein complex assembly GO:0006461 200 0.063
alternative mrna splicing via spliceosome GO:0000380 60 0.061
organic substance catabolic process GO:1901575 308 0.061
axon development GO:0061564 297 0.060
single organism cellular localization GO:1902580 180 0.059
purine nucleoside metabolic process GO:0042278 127 0.059
cytoplasmic transport GO:0016482 130 0.059
organic cyclic compound catabolic process GO:1901361 168 0.059
apoptotic process GO:0006915 159 0.058
eye development GO:0001654 323 0.057
homeostatic process GO:0042592 199 0.057
nucleobase containing small molecule metabolic process GO:0055086 174 0.057
negative regulation of wnt signaling pathway GO:0030178 28 0.057
compound eye morphogenesis GO:0001745 249 0.055
morphogenesis of an epithelium GO:0002009 276 0.055
regulation of intracellular signal transduction GO:1902531 236 0.055
death GO:0016265 284 0.054
compound eye development GO:0048749 307 0.053
sex differentiation GO:0007548 81 0.053
developmental growth GO:0048589 280 0.052
cytoskeleton dependent cytokinesis GO:0061640 81 0.052
regulation of neuron death GO:1901214 26 0.052
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.050
purine ribonucleotide metabolic process GO:0009150 145 0.050
aromatic compound catabolic process GO:0019439 166 0.049
regulation of i kappab kinase nf kappab signaling GO:0043122 2 0.049
cellular response to organic substance GO:0071310 132 0.048
muscle organ development GO:0007517 127 0.048
organonitrogen compound catabolic process GO:1901565 128 0.048
phagocytosis GO:0006909 215 0.047
purine containing compound catabolic process GO:0072523 112 0.047
gene silencing by rna GO:0031047 57 0.046
protein phosphorylation GO:0006468 169 0.046
immune system process GO:0002376 347 0.045
regulation of anatomical structure morphogenesis GO:0022603 242 0.044
response to organic substance GO:0010033 284 0.044
purine ribonucleoside metabolic process GO:0046128 127 0.044
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.044
wnt signaling pathway GO:0016055 98 0.044
ribonucleoprotein complex biogenesis GO:0022613 31 0.042
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.042
negative regulation of multicellular organismal process GO:0051241 142 0.041
purine containing compound metabolic process GO:0072521 155 0.041
nucleoside triphosphate metabolic process GO:0009141 120 0.041
positive regulation of developmental growth GO:0048639 62 0.039
establishment of protein localization GO:0045184 163 0.039
positive regulation of signal transduction GO:0009967 223 0.039
equator specification GO:0045317 4 0.038
purine ribonucleoside catabolic process GO:0046130 112 0.038
axonogenesis GO:0007409 290 0.038
protein localization to nucleus GO:0034504 55 0.037
regulation of cellular catabolic process GO:0031329 157 0.037
anatomical structure homeostasis GO:0060249 97 0.037
protein complex biogenesis GO:0070271 201 0.037
mrna metabolic process GO:0016071 124 0.036
cell cell adhesion via plasma membrane adhesion molecules GO:0098742 26 0.036
positive regulation of phosphate metabolic process GO:0045937 139 0.035
guanosine containing compound catabolic process GO:1901069 74 0.035
positive regulation of gene expression GO:0010628 290 0.035
negative regulation of programmed cell death GO:0043069 72 0.035
nucleocytoplasmic transport GO:0006913 72 0.034
regulation of multi organism process GO:0043900 131 0.034
actomyosin structure organization GO:0031032 56 0.034
regulation of protein modification process GO:0031399 112 0.034
regulation of cell cycle process GO:0010564 181 0.034
negative regulation of response to stimulus GO:0048585 258 0.034
regulation of mrna splicing via spliceosome GO:0048024 64 0.033
ribonucleotide catabolic process GO:0009261 109 0.033
regulation of imaginal disc growth GO:0045570 26 0.033
body morphogenesis GO:0010171 2 0.033
heterocycle catabolic process GO:0046700 166 0.033
cell adhesion GO:0007155 136 0.033
organic substance transport GO:0071702 257 0.032
regulation of organelle organization GO:0033043 196 0.032
purine nucleotide catabolic process GO:0006195 109 0.032
proteolysis GO:0006508 192 0.032
purine nucleoside catabolic process GO:0006152 112 0.032
response to endogenous stimulus GO:0009719 119 0.031
regulation of cellular component biogenesis GO:0044087 201 0.030
single organism intracellular transport GO:1902582 207 0.030
negative regulation of developmental process GO:0051093 201 0.030
cellular response to dna damage stimulus GO:0006974 223 0.029
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.029
regulation of phosphorus metabolic process GO:0051174 210 0.029
positive regulation of phosphorylation GO:0042327 87 0.029
regulation of actin polymerization or depolymerization GO:0008064 27 0.028
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.028
organophosphate catabolic process GO:0046434 112 0.028
positive regulation of response to stimulus GO:0048584 323 0.028
regulation of cell shape GO:0008360 113 0.028
single organism catabolic process GO:0044712 228 0.027
cellular component assembly involved in morphogenesis GO:0010927 151 0.027
modification dependent protein catabolic process GO:0019941 78 0.027
small molecule metabolic process GO:0044281 305 0.027
catabolic process GO:0009056 409 0.026
mitotic spindle organization GO:0007052 220 0.026
positive regulation of rna biosynthetic process GO:1902680 266 0.026
positive regulation of cell communication GO:0010647 250 0.025
membrane organization GO:0061024 112 0.025
nucleotide metabolic process GO:0009117 161 0.025
intracellular protein transport GO:0006886 104 0.025
autophagy GO:0006914 108 0.025
reproductive system development GO:0061458 74 0.025
cellular nitrogen compound catabolic process GO:0044270 165 0.024
reproductive structure development GO:0048608 74 0.024
actin filament polymerization GO:0030041 27 0.024
antimicrobial humoral response GO:0019730 99 0.024
regulation of ras gtpase activity GO:0032318 38 0.024
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.023
protein targeting GO:0006605 64 0.023
negative regulation of signal transduction GO:0009968 206 0.023
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.023
establishment of organelle localization GO:0051656 122 0.023
erbb signaling pathway GO:0038127 58 0.022
lipid localization GO:0010876 54 0.022
tube morphogenesis GO:0035239 191 0.022
lateral inhibition GO:0046331 206 0.022
nucleoside catabolic process GO:0009164 112 0.021
nucleoside metabolic process GO:0009116 127 0.021
regulation of mrna metabolic process GO:1903311 72 0.021
nucleoside phosphate catabolic process GO:1901292 110 0.021
cellular response to oxygen containing compound GO:1901701 79 0.021
positive regulation of biosynthetic process GO:0009891 316 0.021
positive regulation of phosphorus metabolic process GO:0010562 139 0.020
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.020
positive regulation of developmental process GO:0051094 143 0.020
regulation of wnt signaling pathway GO:0030111 68 0.020
cellular macromolecule catabolic process GO:0044265 136 0.020
defense response to other organism GO:0098542 225 0.020
cell proliferation GO:0008283 299 0.020
chromosome segregation GO:0007059 157 0.019
negative regulation of rna metabolic process GO:0051253 251 0.019
regulation of actin filament polymerization GO:0030833 25 0.019
embryo development ending in birth or egg hatching GO:0009792 152 0.018
cell cycle phase transition GO:0044770 140 0.018
inositol lipid mediated signaling GO:0048017 4 0.018
sensory organ morphogenesis GO:0090596 260 0.018
response to organonitrogen compound GO:0010243 75 0.018
cell fate specification GO:0001708 71 0.018
small gtpase mediated signal transduction GO:0007264 88 0.017
single organism membrane organization GO:0044802 93 0.017
response to oxygen containing compound GO:1901700 200 0.017
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.017
ribose phosphate metabolic process GO:0019693 145 0.017
protein localization to organelle GO:0033365 82 0.017
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
regulation of anatomical structure size GO:0090066 163 0.016
single organism membrane budding GO:1902591 2 0.015
response to nitrogen compound GO:1901698 90 0.015
purine nucleotide metabolic process GO:0006163 146 0.015
regulation of cell cycle GO:0051726 291 0.015
regulation of rna splicing GO:0043484 69 0.015
regulation of synaptic growth at neuromuscular junction GO:0008582 89 0.015
striated muscle cell differentiation GO:0051146 90 0.015
secretion GO:0046903 109 0.015
negative regulation of growth GO:0045926 84 0.015
cardiovascular system development GO:0072358 82 0.015
regulation of small gtpase mediated signal transduction GO:0051056 93 0.015
chromatin silencing GO:0006342 76 0.015
gtp catabolic process GO:0006184 72 0.014
regulation of response to stress GO:0080134 200 0.014
regulation of rac protein signal transduction GO:0035020 3 0.014
positive regulation of hydrolase activity GO:0051345 78 0.014
positive regulation of intracellular signal transduction GO:1902533 116 0.014
negative regulation of cellular metabolic process GO:0031324 382 0.014
cell type specific apoptotic process GO:0097285 38 0.014
organonitrogen compound metabolic process GO:1901564 318 0.014
positive regulation of catalytic activity GO:0043085 118 0.014
regulation of nervous system development GO:0051960 248 0.014
regulation of hydrolase activity GO:0051336 97 0.014
regulation of cellular localization GO:0060341 136 0.014
regulation of cell motility GO:2000145 23 0.014
negative regulation of cell death GO:0060548 81 0.014
protein transport GO:0015031 155 0.013
carbohydrate derivative metabolic process GO:1901135 217 0.013
regulation of protein phosphorylation GO:0001932 64 0.013
regulation of nucleotide metabolic process GO:0006140 62 0.013
negative regulation of organelle organization GO:0010639 56 0.013
negative regulation of phosphorylation GO:0042326 35 0.013
wing disc morphogenesis GO:0007472 344 0.013
regulation of ras protein signal transduction GO:0046578 93 0.013
ion transport GO:0006811 145 0.013
ribonucleoside monophosphate catabolic process GO:0009158 39 0.013
negative regulation of neuron death GO:1901215 18 0.013
chemotaxis GO:0006935 249 0.013
response to organic cyclic compound GO:0014070 89 0.013
establishment or maintenance of cell polarity GO:0007163 167 0.013
receptor mediated endocytosis GO:0006898 21 0.013
growth GO:0040007 359 0.013
gtp metabolic process GO:0046039 72 0.012
retina morphogenesis in camera type eye GO:0060042 2 0.012
regulation of apoptotic signaling pathway GO:2001233 10 0.012
activation of jun kinase activity GO:0007257 3 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
regulation of kinase activity GO:0043549 53 0.012
ubiquitin dependent protein catabolic process GO:0006511 78 0.012
nitric oxide metabolic process GO:0046209 1 0.012
positive regulation of immune response GO:0050778 63 0.012
mesenchymal cell development GO:0014031 1 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
positive regulation of endocytosis GO:0045807 22 0.012
cell division GO:0051301 248 0.012
regulation of protein polymerization GO:0032271 28 0.012
regulation of hemocyte proliferation GO:0035206 37 0.011
positive regulation of programmed cell death GO:0043068 62 0.011
response to extracellular stimulus GO:0009991 116 0.011
regulation of phosphorylation GO:0042325 147 0.011
regulation of endocytosis GO:0030100 37 0.011
cellular protein complex assembly GO:0043623 71 0.011
response to dsrna GO:0043331 15 0.011
cation transport GO:0006812 110 0.011
negative regulation of protein metabolic process GO:0051248 85 0.011
positive regulation of innate immune response GO:0045089 38 0.011
establishment of protein localization to organelle GO:0072594 62 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
regulation of g2 m transition of mitotic cell cycle GO:0010389 15 0.011
positive regulation of apoptotic process GO:0043065 47 0.011
cell cycle g2 m phase transition GO:0044839 22 0.011
spindle organization GO:0007051 253 0.011
cellular protein catabolic process GO:0044257 83 0.011
neuron fate commitment GO:0048663 50 0.011
negative regulation of protein binding GO:0032091 1 0.011
regulation of nucleotide catabolic process GO:0030811 48 0.011
intrinsic apoptotic signaling pathway GO:0097193 16 0.011
nucleoside triphosphate catabolic process GO:0009143 108 0.011
positive regulation of growth GO:0045927 75 0.011
actin polymerization or depolymerization GO:0008154 31 0.011
regulation of immune response GO:0050776 118 0.010
response to alcohol GO:0097305 95 0.010
positive regulation of multicellular organismal process GO:0051240 143 0.010
positive regulation of binding GO:0051099 4 0.010
neural retina development GO:0003407 4 0.010
secretion by cell GO:0032940 101 0.010

lig disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of cellular proliferation DOID:14566 0 0.073
cancer DOID:162 0 0.071
organ system cancer DOID:0050686 0 0.071
disease of anatomical entity DOID:7 0 0.038
motor neuron disease DOID:231 0 0.017
central nervous system disease DOID:331 0 0.017
neurodegenerative disease DOID:1289 0 0.017
nervous system disease DOID:863 0 0.017
musculoskeletal system disease DOID:17 0 0.011