Drosophila melanogaster

28 known processes

malpha (Dmel_CG8337)

E(spl) region transcript malpha

(Aliases: E(spl)malpha,E(spl)ma,HLHmalpha,CG8337,Dmel\CG8337)

malpha biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory organ precursor cell fate determination GO:0016360 19 1.000
Fly
cell fate determination involved in pattern specification GO:0060582 19 0.999
Fly
formation of organ boundary GO:0010160 30 0.998
Fly
neuron fate determination GO:0048664 1 0.992
r7 cell differentiation GO:0045466 43 0.973
r1 r6 cell differentiation GO:0048052 4 0.952
formation of anatomical boundary GO:0048859 37 0.938
Fly
regulation of timing of cell differentiation GO:0048505 1 0.930
organ formation GO:0048645 39 0.888
Fly
glial cell fate commitment GO:0021781 3 0.882
cell fate determination GO:0001709 91 0.866
Fly
sensory organ boundary specification GO:0008052 22 0.865
Fly
cell fate commitment involved in pattern specification GO:0060581 31 0.862
Fly
positive regulation of bmp signaling pathway GO:0030513 5 0.835
epithelial cell proliferation involved in renal tubule morphogenesis GO:2001013 11 0.821
primary sex determination soma GO:0007539 2 0.805
stem cell maintenance GO:0019827 67 0.797
sex determination establishment of x a ratio GO:0007540 1 0.787
nephron tubule formation GO:0072079 3 0.714
hindbrain development GO:0030902 2 0.714
axon ensheathment in central nervous system GO:0032291 3 0.712
notch signaling pathway GO:0007219 120 0.671
tyrosine phosphorylation of stat protein GO:0007260 1 0.624
sensory organ morphogenesis GO:0090596 260 0.624
eye morphogenesis GO:0048592 260 0.618
camera type eye development GO:0043010 4 0.615
stem cell fate specification GO:0048866 2 0.587
neuron fate specification GO:0048665 12 0.585
nephron morphogenesis GO:0072028 3 0.583
regulation of hematopoietic progenitor cell differentiation GO:1901532 1 0.578
regulation of notch signaling pathway GO:0008593 100 0.576
Fly
cell fate specification GO:0001708 71 0.569
neuroblast fate specification GO:0014018 2 0.553
regulation of glial cell differentiation GO:0045685 1 0.551
compound eye development GO:0048749 307 0.547
regulation of stem cell proliferation GO:0072091 40 0.535
negative regulation of cellular metabolic process GO:0031324 382 0.534
hair cell differentiation GO:0035315 47 0.518
positive regulation of gene expression GO:0010628 290 0.517
regulation of neuroblast proliferation GO:1902692 34 0.516
stem cell fate commitment GO:0048865 25 0.508
immune system process GO:0002376 347 0.497
photoreceptor cell differentiation GO:0046530 170 0.496
eye photoreceptor cell differentiation GO:0001754 145 0.496
regulation of tyrosine phosphorylation of stat protein GO:0042509 1 0.493
nephron epithelium morphogenesis GO:0072088 3 0.473
negative regulation of cellular biosynthetic process GO:0031327 277 0.464
morphogenesis of embryonic epithelium GO:0016331 94 0.459
regulation of axon extension involved in axon guidance GO:0048841 4 0.453
regulation of multicellular organismal development GO:2000026 414 0.448
negative regulation of rna biosynthetic process GO:1902679 240 0.446
eye development GO:0001654 323 0.443
somatic sex determination GO:0018993 2 0.430
compound eye photoreceptor cell differentiation GO:0001751 140 0.429
nerve development GO:0021675 6 0.423
positive regulation of macromolecule metabolic process GO:0010604 405 0.410
tissue morphogenesis GO:0048729 297 0.405
Fly
negative regulation of transcription dna templated GO:0045892 237 0.392
nephron epithelium development GO:0072009 3 0.391
positive regulation of developmental process GO:0051094 143 0.387
compound eye morphogenesis GO:0001745 249 0.386
regionalization GO:0003002 416 0.379
Fly
regulation of neural precursor cell proliferation GO:2000177 35 0.377
dendrite development GO:0016358 204 0.363
response to external biotic stimulus GO:0043207 293 0.360
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.353
negative regulation of gene expression GO:0010629 387 0.348
positive regulation of cell cycle process GO:0090068 28 0.348
dosage compensation GO:0007549 16 0.346
sex determination GO:0007530 18 0.346
negative regulation of nucleic acid templated transcription GO:1903507 240 0.341
neural precursor cell proliferation GO:0061351 75 0.332
cranial nerve development GO:0021545 1 0.325
embryonic epithelial tube formation GO:0001838 6 0.321
positive regulation of cellular biosynthetic process GO:0031328 316 0.318
adult behavior GO:0030534 137 0.312
stem cell proliferation GO:0072089 88 0.312
cell division GO:0051301 248 0.308
negative regulation of rna metabolic process GO:0051253 251 0.307
peripheral nervous system development GO:0007422 52 0.301
neuroblast proliferation GO:0007405 74 0.297
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.288
connective tissue development GO:0061448 3 0.286
renal tubule morphogenesis GO:0061333 44 0.286
regulation of neurogenesis GO:0050767 158 0.284
positive regulation of multicellular organismal process GO:0051240 143 0.281
regulation of nervous system development GO:0051960 248 0.274
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.270
regulation of response to stress GO:0080134 200 0.263
positive regulation of cellular amine metabolic process GO:0033240 0 0.256
stem cell development GO:0048864 79 0.251
brain development GO:0007420 120 0.247
neuroblast fate commitment GO:0014017 19 0.236
morphogenesis of an epithelium GO:0002009 276 0.232
Fly
tube morphogenesis GO:0035239 191 0.227
regulation of cell development GO:0060284 215 0.223
regulation of gene expression epigenetic GO:0040029 128 0.221
regulation of mitotic cell cycle GO:0007346 190 0.217
axon development GO:0061564 297 0.216
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.215
gliogenesis GO:0042063 80 0.214
single organism behavior GO:0044708 391 0.213
positive regulation of cellular amino acid metabolic process GO:0045764 0 0.212
mitotic nuclear division GO:0007067 213 0.210
neuron projection guidance GO:0097485 241 0.209
locomotory behavior GO:0007626 176 0.209
positive regulation of biosynthetic process GO:0009891 316 0.207
negative regulation of cell development GO:0010721 62 0.207
positive regulation of rna metabolic process GO:0051254 271 0.205
neuronal stem cell maintenance GO:0097150 4 0.204
gland morphogenesis GO:0022612 145 0.203
defense response GO:0006952 300 0.200
larval behavior GO:0030537 42 0.199
nephron tubule morphogenesis GO:0072078 3 0.195
positive regulation of nervous system development GO:0051962 69 0.192
response to abiotic stimulus GO:0009628 341 0.190
dendrite morphogenesis GO:0048813 199 0.189
organelle fission GO:0048285 340 0.186
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.186
regulation of cellular amine metabolic process GO:0033238 3 0.175
tube development GO:0035295 244 0.173
bolwig s organ development GO:0055034 8 0.171
ensheathment of neurons GO:0007272 10 0.170
axonogenesis GO:0007409 290 0.169
adult locomotory behavior GO:0008344 76 0.169
nuclear division GO:0000280 332 0.167
regulation of cell differentiation GO:0045595 302 0.166
neurological system process GO:0050877 358 0.163
regulation of cell cycle process GO:0010564 181 0.159
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.159
smoothened signaling pathway GO:0007224 49 0.157
glial cell proliferation GO:0014009 13 0.156
glial cell development GO:0021782 27 0.153
brain morphogenesis GO:0048854 16 0.152
telencephalon development GO:0021537 2 0.151
humoral immune response GO:0006959 117 0.150
negative regulation of biosynthetic process GO:0009890 277 0.149
regulation of immune system process GO:0002682 176 0.146
neural retina development GO:0003407 4 0.140
peripheral nervous system neuron development GO:0048935 8 0.139
positive regulation of response to stimulus GO:0048584 323 0.139
developmental maturation GO:0021700 172 0.138
forebrain development GO:0030900 2 0.138
positive regulation of nucleic acid templated transcription GO:1903508 266 0.137
positive regulation of notch signaling pathway GO:0045747 34 0.136
regulation of mitosis GO:0007088 56 0.135
regulation of phosphorus metabolic process GO:0051174 210 0.135
positive regulation of cell development GO:0010720 61 0.134
negative regulation of cell differentiation GO:0045596 143 0.134
intracellular signal transduction GO:0035556 300 0.134
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090100 9 0.133
enzyme linked receptor protein signaling pathway GO:0007167 179 0.130
positive regulation of rna biosynthetic process GO:1902680 266 0.130
glial cell differentiation GO:0010001 35 0.130
positive regulation of transcription dna templated GO:0045893 266 0.129
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.128
negative regulation of multicellular organismal process GO:0051241 142 0.127
epithelial tube formation GO:0072175 7 0.127
regulation of protein metabolic process GO:0051246 256 0.126
positive regulation of mitotic cell cycle GO:0045931 34 0.126
imaginal disc pattern formation GO:0007447 91 0.125
neuron fate commitment GO:0048663 50 0.124
positive regulation of protein metabolic process GO:0051247 128 0.124
protein modification process GO:0036211 438 0.122
mesoderm development GO:0007498 78 0.121
positive regulation of phosphate metabolic process GO:0045937 139 0.121
positive regulation of peptidyl tyrosine phosphorylation GO:0050731 4 0.121
open tracheal system development GO:0007424 204 0.121
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.120
body morphogenesis GO:0010171 2 0.120
immune response GO:0006955 246 0.119
positive regulation of cell cycle GO:0045787 43 0.119
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.118
nephron tubule development GO:0072080 3 0.118
peripheral nervous system neuron differentiation GO:0048934 8 0.118
epidermal cell differentiation GO:0009913 51 0.118
cellular protein modification process GO:0006464 438 0.117
small molecule metabolic process GO:0044281 305 0.117
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.115
stem cell differentiation GO:0048863 117 0.114
transcription from rna polymerase ii promoter GO:0006366 368 0.112
regulation of anatomical structure size GO:0090066 163 0.112
regulation of cellular ketone metabolic process GO:0010565 3 0.112
kidney morphogenesis GO:0060993 3 0.110
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.109
cellular amino acid metabolic process GO:0006520 61 0.108
regulation of response to dna damage stimulus GO:2001020 23 0.107
rhythmic process GO:0048511 106 0.107
biological adhesion GO:0022610 138 0.106
hematopoietic progenitor cell differentiation GO:0002244 1 0.105
central nervous system development GO:0007417 201 0.104
segment specification GO:0007379 33 0.102
regulation of cellular amino acid metabolic process GO:0006521 0 0.100
embryonic organ development GO:0048568 50 0.100
positive regulation of programmed cell death GO:0043068 62 0.097
nephron development GO:0072006 3 0.097
axon extension GO:0048675 32 0.096
defense response to other organism GO:0098542 225 0.096
regulation of neuron differentiation GO:0045664 103 0.094
chaeta development GO:0022416 97 0.093
cell maturation GO:0048469 144 0.093
renal system development GO:0072001 72 0.088
epithelial cell differentiation GO:0030855 322 0.087
head development GO:0060322 135 0.087
positive regulation of cell differentiation GO:0045597 64 0.086
positive regulation of signal transduction GO:0009967 223 0.085
positive regulation of molecular function GO:0044093 136 0.084
regulation of cellular response to stress GO:0080135 89 0.083
positive regulation of signaling GO:0023056 243 0.082
positive regulation of cellular protein metabolic process GO:0032270 118 0.082
cell proliferation GO:0008283 299 0.082
negative regulation of stem cell differentiation GO:2000737 8 0.081
immune effector process GO:0002252 98 0.080
regulation of cellular amide metabolic process GO:0034248 39 0.079
positive regulation of cell death GO:0010942 69 0.079
kidney epithelium development GO:0072073 3 0.079
medulla oblongata development GO:0021550 2 0.078
spinal cord patterning GO:0021511 1 0.078
response to biotic stimulus GO:0009607 294 0.077
startle response GO:0001964 16 0.076
somatic stem cell maintenance GO:0035019 14 0.076
salivary gland morphogenesis GO:0007435 145 0.076
organonitrogen compound metabolic process GO:1901564 318 0.076
hematopoietic or lymphoid organ development GO:0048534 57 0.076
establishment of tissue polarity GO:0007164 87 0.076
Fly
epidermis development GO:0008544 65 0.075
respiratory system development GO:0060541 213 0.075
salivary gland development GO:0007431 162 0.074
vesicle mediated transport GO:0016192 381 0.074
proximal distal pattern formation GO:0009954 15 0.073
peptidyl amino acid modification GO:0018193 105 0.073
cellular response to dna damage stimulus GO:0006974 223 0.072
regulation of cellular protein metabolic process GO:0032268 243 0.071
glandular epithelial cell differentiation GO:0002067 1 0.071
regulation of nuclear division GO:0051783 58 0.071
transmission of nerve impulse GO:0019226 12 0.070
cellular amine metabolic process GO:0044106 12 0.070
regulation of molecular function GO:0065009 217 0.070
skin development GO:0043588 65 0.069
neuronal action potential GO:0019228 10 0.067
organic acid metabolic process GO:0006082 103 0.067
neuron projection extension GO:1990138 32 0.066
malpighian tubule morphogenesis GO:0007443 44 0.066
cellular ketone metabolic process GO:0042180 24 0.065
negative regulation of gliogenesis GO:0014014 6 0.064
jak stat cascade GO:0007259 49 0.064
compound eye photoreceptor fate commitment GO:0001752 36 0.064
protein complex biogenesis GO:0070271 201 0.063
developmental cell growth GO:0048588 52 0.063
regulation of cell morphogenesis GO:0022604 163 0.063
regulation of gliogenesis GO:0014013 11 0.062
regulation of cell division GO:0051302 72 0.062
regulation of protein modification process GO:0031399 112 0.062
regulation of axonogenesis GO:0050770 32 0.060
axon guidance GO:0007411 233 0.060
regulation of axon guidance GO:1902667 10 0.059
larval locomotory behavior GO:0008345 27 0.059
protein transport GO:0015031 155 0.059
embryonic hindgut morphogenesis GO:0048619 48 0.058
epithelial cell development GO:0002064 274 0.057
epithelial tube morphogenesis GO:0060562 88 0.057
regulation of intracellular signal transduction GO:1902531 236 0.057
positive regulation of cell division GO:0051781 16 0.056
carboxylic acid metabolic process GO:0019752 92 0.054
negative regulation of nervous system development GO:0051961 92 0.054
regulation of bmp signaling pathway GO:0030510 23 0.054
response to other organism GO:0051707 293 0.053
embryonic morphogenesis GO:0048598 206 0.053
imaginal disc derived appendage morphogenesis GO:0035114 395 0.052
eye photoreceptor cell fate commitment GO:0042706 37 0.052
cell migration GO:0016477 238 0.052
macromolecular complex assembly GO:0065003 256 0.052
positive regulation of cell communication GO:0010647 250 0.051
protein phosphorylation GO:0006468 169 0.051
regulation of membrane potential GO:0042391 35 0.050
protein complex assembly GO:0006461 200 0.050
positive regulation of neural precursor cell proliferation GO:2000179 8 0.050
neuroblast differentiation GO:0014016 29 0.049
regulation of cell cycle GO:0051726 291 0.049
exocrine system development GO:0035272 162 0.049
positive regulation of stem cell proliferation GO:2000648 8 0.048
positive regulation of catalytic activity GO:0043085 118 0.048
response to decreased oxygen levels GO:0036293 58 0.048
positive regulation of neuroblast proliferation GO:0002052 7 0.048
tube formation GO:0035148 21 0.048
negative regulation of notch signaling pathway GO:0045746 41 0.048
Fly
endoderm development GO:0007492 6 0.047
regulation of organelle organization GO:0033043 196 0.047
response to hypoxia GO:0001666 53 0.047
segmentation GO:0035282 207 0.047
regulation of stem cell differentiation GO:2000736 14 0.047
positive regulation of intracellular signal transduction GO:1902533 116 0.046
regulation of catalytic activity GO:0050790 185 0.046
regulation of transmembrane receptor protein serine threonine kinase signaling pathway GO:0090092 38 0.046
cell death GO:0008219 279 0.045
negative regulation of neurogenesis GO:0050768 53 0.044
death GO:0016265 284 0.044
camera type eye morphogenesis GO:0048593 2 0.044
regulation of immune response GO:0050776 118 0.044
axon extension involved in axon guidance GO:0048846 10 0.043
negative regulation of immune system process GO:0002683 50 0.043
negative regulation of developmental process GO:0051093 201 0.043
bmp signaling pathway GO:0030509 27 0.043
epithelial cell proliferation involved in malpighian tubule morphogenesis GO:0061331 11 0.042
oxoacid metabolic process GO:0043436 103 0.042
axon ensheathment GO:0008366 10 0.042
wing disc pattern formation GO:0035222 66 0.042
positive regulation of cellular component organization GO:0051130 156 0.042
protein secretion GO:0009306 45 0.042
establishment of localization in cell GO:0051649 402 0.041
peptidyl tyrosine modification GO:0018212 24 0.041
chaeta morphogenesis GO:0008407 42 0.041
endocytosis GO:0006897 310 0.040
negative regulation of signaling GO:0023057 219 0.040
Fly
positive regulation of protein modification process GO:0031401 58 0.040
transmembrane receptor protein serine threonine kinase signaling pathway GO:0007178 65 0.040
regulation of cyclin dependent protein serine threonine kinase activity GO:0000079 3 0.040
appendage morphogenesis GO:0035107 397 0.040
action potential GO:0001508 13 0.040
multicellular organismal signaling GO:0035637 12 0.039
regulation of programmed cell death GO:0043067 152 0.039
hemopoiesis GO:0030097 46 0.039
positive regulation of phosphorylation GO:0042327 87 0.038
positive regulation of protein kinase activity GO:0045860 25 0.038
cell motility GO:0048870 251 0.037
renal tubule development GO:0061326 64 0.037
organic substance catabolic process GO:1901575 308 0.037
programmed cell death GO:0012501 257 0.037
defense response to bacterium GO:0042742 178 0.036
establishment of ommatidial planar polarity GO:0042067 49 0.036
positive regulation of neurogenesis GO:0050769 41 0.036
regulation of protein kinase activity GO:0045859 51 0.035
multi organism reproductive behavior GO:0044705 121 0.035
photoreceptor cell fate commitment GO:0046552 41 0.035
establishment of planar polarity GO:0001736 87 0.034
Fly
regulation of multi organism process GO:0043900 131 0.033
spinal cord development GO:0021510 1 0.033
macromolecule catabolic process GO:0009057 161 0.033
positive regulation of protein serine threonine kinase activity GO:0071902 15 0.033
stem cell fate determination GO:0048867 15 0.033
negative regulation of mitotic cell cycle GO:0045930 109 0.032
negative regulation of signal transduction GO:0009968 206 0.032
Fly
regulation of cell morphogenesis involved in differentiation GO:0010769 61 0.032
regulation of cellular component size GO:0032535 98 0.031
bolwig s organ morphogenesis GO:0001746 8 0.031
regulation of growth GO:0040008 233 0.031
r8 cell fate commitment GO:0007460 6 0.031
phosphorylation GO:0016310 294 0.031
regulation of cell projection organization GO:0031344 92 0.030
immune system development GO:0002520 57 0.030
regulation of peptidyl tyrosine phosphorylation GO:0050730 10 0.030
positive regulation of phosphorus metabolic process GO:0010562 139 0.030
appendage development GO:0048736 401 0.030
neuroepithelial cell differentiation GO:0060563 6 0.030
neuromuscular process GO:0050905 21 0.030
response to oxygen levels GO:0070482 59 0.030
regulation of immune effector process GO:0002697 52 0.030
regulation of phosphorylation GO:0042325 147 0.029
growth GO:0040007 359 0.029
cellular component assembly involved in morphogenesis GO:0010927 151 0.029
cardiovascular system development GO:0072358 82 0.028
negative regulation of cell communication GO:0010648 223 0.028
Fly
cell adhesion GO:0007155 136 0.028
negative regulation of cell cycle process GO:0010948 109 0.027
retina development in camera type eye GO:0060041 4 0.027
regulation of epithelial cell differentiation GO:0030856 4 0.027
regulation of cell death GO:0010941 173 0.027
positive regulation of kinase activity GO:0033674 25 0.027
regulation of developmental growth GO:0048638 174 0.027
negative regulation of programmed cell death GO:0043069 72 0.026
digestive tract morphogenesis GO:0048546 127 0.026
regulation of cell proliferation GO:0042127 163 0.026
oenocyte development GO:0007438 8 0.026
positive regulation of organelle organization GO:0010638 65 0.026
organic substance transport GO:0071702 257 0.026
regulation of localization GO:0032879 275 0.026
retina morphogenesis in camera type eye GO:0060042 2 0.026
multicellular organismal reproductive behavior GO:0033057 110 0.025
response to bacterium GO:0009617 198 0.025
protein localization GO:0008104 284 0.024
ommatidial rotation GO:0016318 20 0.024
peptidyl tyrosine phosphorylation GO:0018108 24 0.024
homeostatic process GO:0042592 199 0.024
positive regulation of cell proliferation GO:0008284 47 0.024
establishment of protein localization GO:0045184 163 0.024
cell growth GO:0016049 108 0.024
regulation of glial cell proliferation GO:0060251 11 0.024
hindgut morphogenesis GO:0007442 58 0.023
muscle cell differentiation GO:0042692 103 0.023
muscle organ development GO:0007517 127 0.022
wound healing GO:0042060 75 0.022
positive regulation of transferase activity GO:0051347 26 0.022
antimicrobial humoral response GO:0019730 99 0.022
proteolysis GO:0006508 192 0.022
regulation of kinase activity GO:0043549 53 0.021
regulation of cellular localization GO:0060341 136 0.021
regulation of reproductive process GO:2000241 54 0.021
negative regulation of neuron differentiation GO:0045665 16 0.021
spinal cord dorsal ventral patterning GO:0021513 1 0.021
developmental growth involved in morphogenesis GO:0060560 65 0.021
formation of primary germ layer GO:0001704 24 0.021
regulation of transferase activity GO:0051338 58 0.020
cellular catabolic process GO:0044248 372 0.020
regulation of antimicrobial peptide biosynthetic process GO:0002805 38 0.020
dorsal ventral pattern formation imaginal disc GO:0007450 51 0.020
negative regulation of glial cell proliferation GO:0060253 6 0.020
urogenital system development GO:0001655 72 0.020
camera type eye photoreceptor cell differentiation GO:0060219 2 0.020
regulation of neuron projection development GO:0010975 69 0.019
catabolic process GO:0009056 409 0.019
positive regulation of protein phosphorylation GO:0001934 34 0.019
regulation of establishment of protein localization GO:0070201 61 0.019
amine metabolic process GO:0009308 12 0.019
wing disc dorsal ventral pattern formation GO:0048190 47 0.019
chemotaxis GO:0006935 249 0.019
regulation of axon extension GO:0030516 8 0.018
kidney development GO:0001822 3 0.018
apoptotic process GO:0006915 159 0.018
regulation of protein phosphorylation GO:0001932 64 0.018
regulation of dendrite development GO:0050773 37 0.018
gastrulation with mouth forming first GO:0001703 36 0.018
regulation of antimicrobial peptide production GO:0002784 44 0.018
circadian rhythm GO:0007623 105 0.018
chromatin organization GO:0006325 207 0.017
positive regulation of developmental growth GO:0048639 62 0.017
regulation of humoral immune response GO:0002920 51 0.017
regulation of production of molecular mediator of immune response GO:0002700 44 0.017
central nervous system neuron differentiation GO:0021953 8 0.017
imaginal disc derived leg morphogenesis GO:0007480 80 0.017
antimicrobial peptide biosynthetic process GO:0002777 38 0.017
production of molecular mediator of immune response GO:0002440 46 0.017
epidermal growth factor receptor signaling pathway GO:0007173 58 0.017
leg disc development GO:0035218 92 0.017
developmental pigmentation GO:0048066 68 0.017
regulation of erbb signaling pathway GO:1901184 42 0.017
phagocytosis GO:0006909 215 0.017
imaginal disc derived wing vein specification GO:0007474 48 0.016
positive regulation of cellular component biogenesis GO:0044089 80 0.016
apoptotic process involved in morphogenesis GO:0060561 3 0.015
columnar cuboidal epithelial cell development GO:0002066 249 0.015
anterior posterior pattern specification GO:0009952 136 0.015
antennal joint development GO:0048098 5 0.015
organelle assembly GO:0070925 198 0.015
gland development GO:0048732 191 0.015
multi organism behavior GO:0051705 175 0.015
regulation of phosphate metabolic process GO:0019220 210 0.014
positive regulation of histone deacetylation GO:0031065 2 0.014
mesenchymal cell differentiation GO:0048762 1 0.014
positive regulation of protein transport GO:0051222 37 0.014
nucleobase containing compound catabolic process GO:0034655 165 0.014
regulation of hemocyte proliferation GO:0035206 37 0.014
muscle fiber development GO:0048747 12 0.014
response to wounding GO:0009611 94 0.014
synapse organization GO:0050808 196 0.014
regulation of oviposition GO:0046662 14 0.014
localization of cell GO:0051674 257 0.014
negative regulation of response to stimulus GO:0048585 258 0.014
Fly
mushroom body development GO:0016319 70 0.014
regulation of cell size GO:0008361 63 0.014
imaginal disc derived wing morphogenesis GO:0007476 337 0.013
striated muscle cell development GO:0055002 50 0.013
leg disc morphogenesis GO:0007478 80 0.013
regulation of jak stat cascade GO:0046425 43 0.013
developmental growth GO:0048589 280 0.013
central nervous system neuron development GO:0021954 8 0.013
embryonic organ morphogenesis GO:0048562 5 0.013
negative regulation of cell cycle GO:0045786 116 0.013
positive regulation of epithelial cell differentiation GO:0030858 1 0.013
retinal cone cell differentiation GO:0042670 2 0.013
positive regulation of apoptotic process GO:0043065 47 0.013
cellular response to chemical stimulus GO:0070887 199 0.012
positive regulation of neuron differentiation GO:0045666 26 0.012
regulation of dendrite morphogenesis GO:0048814 28 0.012
larval development GO:0002164 104 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.012
limb development GO:0060173 1 0.012
chromosome organization GO:0051276 360 0.012
negative regulation of apoptotic process GO:0043066 63 0.012
covalent chromatin modification GO:0016569 106 0.012
organic cyclic compound catabolic process GO:1901361 168 0.012
cellular macromolecule catabolic process GO:0044265 136 0.011
regulation of transport GO:0051049 181 0.011
malpighian tubule tip cell differentiation GO:0061382 9 0.011
taxis GO:0042330 304 0.011
establishment or maintenance of cell polarity GO:0007163 167 0.011
regulation of proteolysis GO:0030162 87 0.011
cell recognition GO:0008037 102 0.011
mating behavior GO:0007617 106 0.011
intracellular transport GO:0046907 228 0.011
neuron recognition GO:0008038 101 0.011
striated muscle cell differentiation GO:0051146 90 0.011

malpha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
spondylocostal dysostosis DOID:0050568 0 0.740
bone development disease DOID:0080006 0 0.740
bone disease DOID:0080001 0 0.740
disease of anatomical entity DOID:7 0 0.740
dysostosis DOID:1934 0 0.740
musculoskeletal system disease DOID:17 0 0.740
connective tissue disease DOID:65 0 0.740