Drosophila melanogaster

0 known processes

kl-2 (Dmel_CG17866)

male fertility factor kl2

(Aliases: CG40438,CG17866,Dmel\CG17866,Lms2)

kl-2 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
spermatid development GO:0007286 98 0.488
spermatid differentiation GO:0048515 114 0.408
spermatogenesis GO:0007283 200 0.339
male gamete generation GO:0048232 201 0.276
organelle fission GO:0048285 340 0.151
male meiosis GO:0007140 52 0.104
meiotic nuclear division GO:0007126 151 0.071
meiotic cell cycle GO:0051321 171 0.070
organelle assembly GO:0070925 198 0.069
centrosome cycle GO:0007098 137 0.061
positive regulation of rna biosynthetic process GO:1902680 266 0.058
positive regulation of cellular biosynthetic process GO:0031328 316 0.049
microtubule organizing center organization GO:0031023 168 0.047
nuclear division GO:0000280 332 0.044
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.041
positive regulation of macromolecule metabolic process GO:0010604 405 0.041
transcription from rna polymerase ii promoter GO:0006366 368 0.041
synaptic transmission GO:0007268 288 0.040
protein complex biogenesis GO:0070271 201 0.040
single organism behavior GO:0044708 391 0.038
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.037
positive regulation of biosynthetic process GO:0009891 316 0.034
cellularization GO:0007349 90 0.033
sperm individualization GO:0007291 48 0.032
male meiosis cytokinesis GO:0007112 26 0.031
centrosome organization GO:0051297 163 0.031
regulation of microtubule based process GO:0032886 49 0.031
meiotic cytokinesis GO:0033206 33 0.031
negative regulation of cellular component organization GO:0051129 108 0.030
cellular protein modification process GO:0006464 438 0.029
positive regulation of gene expression GO:0010628 290 0.028
cytoskeleton dependent cytokinesis GO:0061640 81 0.028
actin cytoskeleton organization GO:0030036 206 0.028
chromosome organization GO:0051276 360 0.028
cell division GO:0051301 248 0.028
regulation of organelle organization GO:0033043 196 0.028
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.027
positive regulation of nucleic acid templated transcription GO:1903508 266 0.027
cognition GO:0050890 141 0.027
appendage morphogenesis GO:0035107 397 0.026
regulation of protein metabolic process GO:0051246 256 0.025
programmed cell death GO:0012501 257 0.025
body morphogenesis GO:0010171 2 0.025
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.024
spindle organization GO:0007051 253 0.024
establishment of localization in cell GO:0051649 402 0.023
positive regulation of transcription dna templated GO:0045893 266 0.023
learning or memory GO:0007611 141 0.023
protein modification process GO:0036211 438 0.023
macromolecular complex assembly GO:0065003 256 0.022
developmental programmed cell death GO:0010623 138 0.022
neurological system process GO:0050877 358 0.022
negative regulation of response to stimulus GO:0048585 258 0.022
negative regulation of cell cycle phase transition GO:1901988 103 0.022
positive regulation of rna metabolic process GO:0051254 271 0.021
regulation of cell cycle GO:0051726 291 0.021
positive regulation of cysteine type endopeptidase activity GO:2001056 24 0.021
organonitrogen compound metabolic process GO:1901564 318 0.020
spindle assembly GO:0051225 80 0.020
protein complex assembly GO:0006461 200 0.020
salivary gland morphogenesis GO:0007435 145 0.019
meiosis ii GO:0007135 23 0.019
microtubule based transport GO:0010970 42 0.019
mitochondrion organization GO:0007005 65 0.019
regulation of cell cycle phase transition GO:1901987 130 0.019
salivary gland development GO:0007431 162 0.019
regulation of synapse structure and activity GO:0050803 128 0.019
organic substance transport GO:0071702 257 0.019
regulation of cellular protein metabolic process GO:0032268 243 0.019
oxoacid metabolic process GO:0043436 103 0.019
learning GO:0007612 75 0.018
wing disc morphogenesis GO:0007472 344 0.018
organic substance catabolic process GO:1901575 308 0.018
mitotic cell cycle checkpoint GO:0007093 88 0.018
regulation of transport GO:0051049 181 0.018
response to organic substance GO:0010033 284 0.018
dorsal appendage formation GO:0046843 47 0.018
small molecule metabolic process GO:0044281 305 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
regulation of mitotic cell cycle phase transition GO:1901990 130 0.017
chemosensory behavior GO:0007635 106 0.017
response to abiotic stimulus GO:0009628 341 0.017
chorion containing eggshell formation GO:0007304 105 0.017
regulation of response to external stimulus GO:0032101 115 0.017
positive regulation of proteolysis GO:0045862 52 0.017
eggshell formation GO:0030703 105 0.016
negative regulation of mitotic cell cycle GO:0045930 109 0.016
single organism catabolic process GO:0044712 228 0.016
nucleus organization GO:0006997 45 0.016
protein processing GO:0016485 68 0.016
mitotic cell cycle phase transition GO:0044772 138 0.016
meiotic spindle organization GO:0000212 36 0.016
translation GO:0006412 69 0.016
ribonucleoside triphosphate metabolic process GO:0009199 119 0.016
histolysis GO:0007559 102 0.016
negative regulation of cell communication GO:0010648 223 0.016
endomembrane system organization GO:0010256 119 0.016
tissue death GO:0016271 102 0.016
eggshell chorion assembly GO:0007306 66 0.016
detection of abiotic stimulus GO:0009582 66 0.015
catabolic process GO:0009056 409 0.015
purine ribonucleoside triphosphate metabolic process GO:0009205 119 0.015
negative regulation of translation GO:0017148 28 0.015
single organism membrane organization GO:0044802 93 0.015
multicellular organismal reproductive behavior GO:0033057 110 0.015
regulation of molecular function GO:0065009 217 0.015
compound eye morphogenesis GO:0001745 249 0.015
olfactory behavior GO:0042048 97 0.014
phagocytosis GO:0006909 215 0.014
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.014
organic acid metabolic process GO:0006082 103 0.014
cell cycle checkpoint GO:0000075 95 0.014
eye morphogenesis GO:0048592 260 0.014
cellular response to dna damage stimulus GO:0006974 223 0.014
golgi organization GO:0007030 66 0.014
negative regulation of signal transduction GO:0009968 206 0.014
negative regulation of signaling GO:0023057 219 0.014
centrosome duplication GO:0051298 121 0.014
microtubule based movement GO:0007018 51 0.014
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.014
cell cycle phase transition GO:0044770 140 0.014
response to lipopolysaccharide GO:0032496 4 0.014
cytoskeleton dependent intracellular transport GO:0030705 44 0.014
sister chromatid segregation GO:0000819 92 0.013
regulation of cellular catabolic process GO:0031329 157 0.013
regulation of cell cycle process GO:0010564 181 0.013
mitotic spindle organization GO:0007052 220 0.013
response to organic cyclic compound GO:0014070 89 0.013
regulation of translation GO:0006417 56 0.013
eye development GO:0001654 323 0.013
negative regulation of cellular metabolic process GO:0031324 382 0.013
cellular amino acid metabolic process GO:0006520 61 0.013
cytokinetic process GO:0032506 27 0.013
nucleoside triphosphate metabolic process GO:0009141 120 0.013
imaginal disc derived appendage development GO:0048737 399 0.013
regulation of catalytic activity GO:0050790 185 0.013
regulation of cellular amine metabolic process GO:0033238 3 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
compound eye development GO:0048749 307 0.013
photoreceptor cell differentiation GO:0046530 170 0.013
intracellular signal transduction GO:0035556 300 0.013
response to light stimulus GO:0009416 124 0.013
single organism membrane fusion GO:0044801 42 0.013
cytokinesis GO:0000910 90 0.013
anion homeostasis GO:0055081 3 0.013
meiotic cell cycle process GO:1903046 132 0.012
response to oxygen containing compound GO:1901700 200 0.012
cell death GO:0008219 279 0.012
cellular catabolic process GO:0044248 372 0.012
imaginal disc derived wing morphogenesis GO:0007476 337 0.012
proteolysis GO:0006508 192 0.012
regulation of cellular localization GO:0060341 136 0.012
vesicle mediated transport GO:0016192 381 0.012
single organism intracellular transport GO:1902582 207 0.012
gland morphogenesis GO:0022612 145 0.012
protein maturation GO:0051604 71 0.012
immune system process GO:0002376 347 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
exocrine system development GO:0035272 162 0.012
cellular response to radiation GO:0071478 52 0.012
developmental maturation GO:0021700 172 0.012
sensory perception of pain GO:0019233 4 0.012
cellular response to chemical stimulus GO:0070887 199 0.012
response to radiation GO:0009314 155 0.012
positive regulation of response to stimulus GO:0048584 323 0.012
carbohydrate derivative metabolic process GO:1901135 217 0.012
death GO:0016265 284 0.011
regulation of hydrolase activity GO:0051336 97 0.011
protein localization GO:0008104 284 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
response to external biotic stimulus GO:0043207 293 0.011
segmentation GO:0035282 207 0.011
negative regulation of gene expression GO:0010629 387 0.011
positive regulation of cellular protein metabolic process GO:0032270 118 0.011
salivary gland histolysis GO:0035070 88 0.011
amine metabolic process GO:0009308 12 0.011
endocytosis GO:0006897 310 0.011
forebrain development GO:0030900 2 0.011
phosphorylation GO:0016310 294 0.011
regulation of g protein coupled receptor protein signaling pathway GO:0008277 23 0.011
dna conformation change GO:0071103 105 0.011
membrane fusion GO:0061025 42 0.011
macromolecule catabolic process GO:0009057 161 0.011
cellular macromolecule localization GO:0070727 220 0.011
apoptotic process GO:0006915 159 0.011
dorsal ventral pattern formation GO:0009953 133 0.011
cellular component assembly involved in morphogenesis GO:0010927 151 0.011
regulation of mitotic cell cycle GO:0007346 190 0.011
negative regulation of cellular biosynthetic process GO:0031327 277 0.011
organophosphate metabolic process GO:0019637 195 0.011
cellular response to organic substance GO:0071310 132 0.011
circadian sleep wake cycle process GO:0022410 24 0.011
telencephalon development GO:0021537 2 0.011
regulation of programmed cell death GO:0043067 152 0.011
mitotic nuclear division GO:0007067 213 0.011
regulation of anatomical structure morphogenesis GO:0022603 242 0.011
membrane organization GO:0061024 112 0.011
regulation of cellular ketone metabolic process GO:0010565 3 0.011
negative regulation of biosynthetic process GO:0009890 277 0.011
axon cargo transport GO:0008088 29 0.011
cellular amine metabolic process GO:0044106 12 0.010
cellular protein localization GO:0034613 160 0.010
antimicrobial humoral response GO:0019730 99 0.010
actin filament based process GO:0030029 220 0.010
mitotic sister chromatid segregation GO:0000070 87 0.010
epithelial cell differentiation GO:0030855 322 0.010
developmental growth GO:0048589 280 0.010
autophagic cell death GO:0048102 83 0.010
negative regulation of cell cycle process GO:0010948 109 0.010
defense response GO:0006952 300 0.010
cytoplasmic transport GO:0016482 130 0.010
positive regulation of catalytic activity GO:0043085 118 0.010
cellular macromolecule catabolic process GO:0044265 136 0.010
ribose phosphate metabolic process GO:0019693 145 0.010
lateral inhibition GO:0046331 206 0.010
axis specification GO:0009798 167 0.010
chemical homeostasis GO:0048878 92 0.010
response to bacterium GO:0009617 198 0.010

kl-2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.023
nervous system disease DOID:863 0 0.020
sensory system disease DOID:0050155 0 0.011