Drosophila melanogaster

103 known processes

U2af50 (Dmel_CG9998)

U2 small nuclear riboprotein auxiliary factor 50

(Aliases: DU2AF50,U2af,Dmel\CG9998,U2AF-50,DmU2AF[50],l(1)14Cc,dU2AF[50],l(1)9-21,U2AF50,U2AF,dUTAf[50],9-21,l(1)14Ca,dU2AF50,CG9998)

U2af50 biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
rna processing GO:0006396 147 0.857
spindle organization GO:0007051 253 0.826
nuclear division GO:0000280 332 0.801
Worm
mitotic g2 m transition checkpoint GO:0044818 70 0.794
mrna processing GO:0006397 104 0.754
mitotic spindle organization GO:0007052 220 0.701
mrna splicing via spliceosome GO:0000398 73 0.693
rna splicing GO:0008380 83 0.684
rna splicing via transesterification reactions with bulged adenosine as nucleophile GO:0000377 73 0.677
meiotic cell cycle GO:0051321 171 0.640
Worm
embryo development ending in birth or egg hatching GO:0009792 152 0.592
Worm
organelle fission GO:0048285 340 0.585
Worm
regulation of mrna splicing via spliceosome GO:0048024 64 0.485
mrna metabolic process GO:0016071 124 0.476
positive regulation of macromolecule metabolic process GO:0010604 405 0.440
Human
rna splicing via transesterification reactions GO:0000375 73 0.425
molting cycle GO:0042303 56 0.396
mitotic cell cycle phase transition GO:0044772 138 0.368
development of primary sexual characteristics GO:0045137 50 0.328
Worm
cellular response to dna damage stimulus GO:0006974 223 0.291
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.291
chromatin assembly or disassembly GO:0006333 52 0.287
g2 dna damage checkpoint GO:0031572 69 0.283
cell cycle phase transition GO:0044770 140 0.267
mitotic g2 dna damage checkpoint GO:0007095 69 0.265
regulation of meiosis GO:0040020 3 0.249
Worm
positive regulation of transcription from rna polymerase ii promoter GO:0045944 204 0.225
mitotic dna integrity checkpoint GO:0044774 75 0.221
mitotic dna damage checkpoint GO:0044773 74 0.220
regulation of mitotic cell cycle phase transition GO:1901990 130 0.202
body morphogenesis GO:0010171 2 0.199
Worm
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.192
Human Fly
regulation of cell cycle phase transition GO:1901987 130 0.180
rrna processing GO:0006364 3 0.173
positive regulation of gene expression GO:0010628 290 0.173
Human
negative regulation of cellular metabolic process GO:0031324 382 0.167
Human Fly
regulation of meiotic cell cycle GO:0051445 9 0.167
Worm
meiotic nuclear division GO:0007126 151 0.155
Worm
negative regulation of cell cycle process GO:0010948 109 0.152
regulation of cell cycle GO:0051726 291 0.150
Worm
sex differentiation GO:0007548 81 0.150
Worm
dna integrity checkpoint GO:0031570 81 0.149
chromatin organization GO:0006325 207 0.147
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.140
Human
negative regulation of cell cycle phase transition GO:1901988 103 0.119
regulation of intracellular signal transduction GO:1902531 236 0.119
mitotic sister chromatid segregation GO:0000070 87 0.118
cell division GO:0051301 248 0.117
Worm
positive regulation of rna metabolic process GO:0051254 271 0.114
Human
regulation of mitotic cell cycle GO:0007346 190 0.113
growth GO:0040007 359 0.106
Worm
alternative mrna splicing via spliceosome GO:0000380 60 0.105
mitotic nuclear division GO:0007067 213 0.103
protein modification process GO:0036211 438 0.097
negative regulation of mitotic cell cycle GO:0045930 109 0.095
gonad development GO:0008406 50 0.095
Worm
negative regulation of cellular biosynthetic process GO:0031327 277 0.086
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.085
Human Fly
endocytosis GO:0006897 310 0.083
positive regulation of transcription dna templated GO:0045893 266 0.082
positive regulation of signaling GO:0023056 243 0.082
positive regulation of cell communication GO:0010647 250 0.081
regulation of cell cycle process GO:0010564 181 0.081
Worm
dendrite development GO:0016358 204 0.079
positive regulation of cellular biosynthetic process GO:0031328 316 0.079
negative regulation of cell cycle GO:0045786 116 0.077
ribonucleoprotein complex biogenesis GO:0022613 31 0.076
positive regulation of response to stimulus GO:0048584 323 0.073
mrna cis splicing via spliceosome GO:0045292 1 0.072
cellular catabolic process GO:0044248 372 0.072
mitotic cell cycle checkpoint GO:0007093 88 0.071
sister chromatid segregation GO:0000819 92 0.069
regulation of transcription elongation from rna polymerase ii promoter GO:0034243 15 0.068
transcription from rna polymerase ii promoter GO:0006366 368 0.067
macromolecular complex assembly GO:0065003 256 0.066
regulation of mrna metabolic process GO:1903311 72 0.066
protein dna complex subunit organization GO:0071824 86 0.065
cell cycle checkpoint GO:0000075 95 0.064
dendrite morphogenesis GO:0048813 199 0.062
reproductive structure development GO:0048608 74 0.061
Worm
phosphorylation GO:0016310 294 0.058
larval development GO:0002164 104 0.057
Worm
ribonucleoprotein complex subunit organization GO:0071826 28 0.056
negative regulation of gene expression GO:0010629 387 0.055
Human Fly
regulation of catalytic activity GO:0050790 185 0.055
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.054
Human
cellular macromolecular complex assembly GO:0034622 153 0.048
regulation of mrna processing GO:0050684 71 0.048
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.048
intracellular signal transduction GO:0035556 300 0.048
death GO:0016265 284 0.047
regulation of rna splicing GO:0043484 69 0.046
chromosome organization GO:0051276 360 0.045
negative regulation of nucleic acid templated transcription GO:1903507 240 0.040
dna metabolic process GO:0006259 227 0.040
programmed cell death GO:0012501 257 0.040
ncrna processing GO:0034470 30 0.040
intermediate filament based process GO:0045103 1 0.037
cell death GO:0008219 279 0.035
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.035
positive regulation of nucleic acid templated transcription GO:1903508 266 0.034
cellular protein modification process GO:0006464 438 0.033
positive regulation of signal transduction GO:0009967 223 0.033
rna polymerase ii transcriptional preinitiation complex assembly GO:0051123 20 0.033
regulation of heterochromatin assembly GO:0031445 8 0.032
centrosome duplication GO:0051298 121 0.030
positive regulation of biosynthetic process GO:0009891 316 0.030
mrna splice site selection GO:0006376 1 0.030
catabolic process GO:0009056 409 0.029
eye development GO:0001654 323 0.028
regulation of molecular function GO:0065009 217 0.028
phagocytosis GO:0006909 215 0.028
reproductive system development GO:0061458 74 0.027
Worm
ncrna metabolic process GO:0034660 43 0.027
vesicle mediated transport GO:0016192 381 0.026
organelle assembly GO:0070925 198 0.025
genitalia development GO:0048806 26 0.024
Worm
organic substance catabolic process GO:1901575 308 0.023
carbohydrate derivative metabolic process GO:1901135 217 0.023
gene silencing GO:0016458 138 0.023
Fly
negative regulation of meiotic cell cycle GO:0051447 2 0.023
negative regulation of transcription from rna polymerase ii promoter GO:0000122 119 0.023
regulation of cell division GO:0051302 72 0.022
Worm
stem cell differentiation GO:0048863 117 0.021
dna templated transcription elongation GO:0006354 18 0.020
protein complex biogenesis GO:0070271 201 0.020
myofibril assembly GO:0030239 36 0.020
protein complex assembly GO:0006461 200 0.019
translation GO:0006412 69 0.019
apoptotic process GO:0006915 159 0.019
nuclear transport GO:0051169 72 0.019
regulation of cell morphogenesis GO:0022604 163 0.018
regulation of alternative mrna splicing via spliceosome GO:0000381 60 0.018
positive regulation of rho protein signal transduction GO:0035025 4 0.018
regulation of chromosome organization GO:0033044 64 0.018
spermatid development GO:0007286 98 0.018
regulation of hemocyte proliferation GO:0035206 37 0.018
cell proliferation GO:0008283 299 0.018
Worm
regulation of localization GO:0032879 275 0.018
imaginal disc derived appendage development GO:0048737 399 0.017
regulation of cellular protein metabolic process GO:0032268 243 0.017
posttranscriptional regulation of gene expression GO:0010608 145 0.017
stem cell maintenance GO:0019827 67 0.017
regulation of growth GO:0040008 233 0.017
regulation of phosphorylation GO:0042325 147 0.016
immune system process GO:0002376 347 0.016
regulation of translation GO:0006417 56 0.016
spliceosomal complex assembly GO:0000245 1 0.016
positive regulation of binding GO:0051099 4 0.016
regulation of cellular ketone metabolic process GO:0010565 3 0.016
regulation of phosphate metabolic process GO:0019220 210 0.015
negative regulation of protein complex disassembly GO:0043242 23 0.015
dna replication GO:0006260 48 0.015
organonitrogen compound metabolic process GO:1901564 318 0.015
cellular amino acid metabolic process GO:0006520 61 0.015
regulation of developmental growth GO:0048638 174 0.014
positive regulation of molecular function GO:0044093 136 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
regulation of cell death GO:0010941 173 0.014
camera type eye development GO:0043010 4 0.013
dna damage checkpoint GO:0000077 78 0.013
small gtpase mediated signal transduction GO:0007264 88 0.013
nucleosome organization GO:0034728 59 0.013
regulation of dna templated transcription elongation GO:0032784 17 0.013
microtubule organizing center organization GO:0031023 168 0.013
regulation of chromatin assembly GO:0010847 9 0.012
response to oxygen containing compound GO:1901700 200 0.012
regulation of phosphorus metabolic process GO:0051174 210 0.012
regulation of phosphoprotein phosphatase activity GO:0043666 3 0.012
regulation of protein catabolic process GO:0042176 55 0.012
cell chemotaxis involved in malpighian tubule morphogenesis GO:0061352 3 0.012
oocyte development GO:0048599 124 0.012
ribonucleoprotein complex assembly GO:0022618 23 0.012
ribose phosphate metabolic process GO:0019693 145 0.012
gene silencing by rna GO:0031047 57 0.011
biological adhesion GO:0022610 138 0.011
regulation of chromatin organization GO:1902275 32 0.011
regionalization GO:0003002 416 0.011
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.011
mitochondrial membrane organization GO:0007006 3 0.011
peptidyl lysine methylation GO:0018022 16 0.011
positive regulation of cellular component organization GO:0051130 156 0.011
spindle assembly GO:0051225 80 0.011
negative regulation of transcription dna templated GO:0045892 237 0.011
unsaturated fatty acid biosynthetic process GO:0006636 1 0.011
organelle localization GO:0051640 148 0.010
cell cycle g1 s phase transition GO:0044843 31 0.010
nucleobase containing small molecule metabolic process GO:0055086 174 0.010
negative regulation of cellular component organization GO:0051129 108 0.010
posttranscriptional gene silencing GO:0016441 46 0.010

U2af50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.043
nervous system disease DOID:863 0 0.043