Drosophila melanogaster

40 known processes

Gen (Dmel_CG10670)

XPG-like endonuclease

(Aliases: DmGEN,BcDNA:GM10765,Dmel\CG10670,CG10670)

Gen biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
response to abiotic stimulus GO:0009628 341 0.067
chromosome organization GO:0051276 360 0.063
chromosome segregation GO:0007059 157 0.050
nuclear division GO:0000280 332 0.043
spindle organization GO:0007051 253 0.041
regulation of cell cycle GO:0051726 291 0.039
Human
proteolysis GO:0006508 192 0.039
dna metabolic process GO:0006259 227 0.037
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.035
compound eye development GO:0048749 307 0.035
regulation of mitotic cell cycle GO:0007346 190 0.032
Human
organic substance catabolic process GO:1901575 308 0.032
heterocycle catabolic process GO:0046700 166 0.032
regulation of cell cycle process GO:0010564 181 0.032
Human
positive regulation of response to stimulus GO:0048584 323 0.031
organonitrogen compound metabolic process GO:1901564 318 0.031
single organism behavior GO:0044708 391 0.031
eye development GO:0001654 323 0.031
ubiquitin dependent protein catabolic process GO:0006511 78 0.030
organic substance transport GO:0071702 257 0.030
negative regulation of gene expression GO:0010629 387 0.030
Human
regulation of organelle organization GO:0033043 196 0.030
Human
cellular catabolic process GO:0044248 372 0.029
open tracheal system development GO:0007424 204 0.028
sister chromatid segregation GO:0000819 92 0.028
taxis GO:0042330 304 0.028
small molecule metabolic process GO:0044281 305 0.028
body morphogenesis GO:0010171 2 0.027
protein complex biogenesis GO:0070271 201 0.027
mitotic spindle organization GO:0007052 220 0.027
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.026
intracellular transport GO:0046907 228 0.026
protein modification process GO:0036211 438 0.026
respiratory system development GO:0060541 213 0.025
regulation of mitotic cell cycle phase transition GO:1901990 130 0.025
Human
mitotic cell cycle phase transition GO:0044772 138 0.025
chromosome separation GO:0051304 42 0.024
macromolecule catabolic process GO:0009057 161 0.024
negative regulation of cellular metabolic process GO:0031324 382 0.024
Human
regulation of multicellular organismal development GO:2000026 414 0.023
lateral inhibition GO:0046331 206 0.023
positive regulation of cellular biosynthetic process GO:0031328 316 0.023
cell fate determination GO:0001709 91 0.023
cytoplasmic transport GO:0016482 130 0.023
regulation of protein metabolic process GO:0051246 256 0.023
Human
compound eye morphogenesis GO:0001745 249 0.023
death GO:0016265 284 0.023
mitotic nuclear division GO:0007067 213 0.023
dna repair GO:0006281 54 0.022
imaginal disc derived appendage development GO:0048737 399 0.022
regulation of cellular amine metabolic process GO:0033238 3 0.022
regulation of catabolic process GO:0009894 170 0.022
Human
regulation of cellular protein metabolic process GO:0032268 243 0.022
Human
positive regulation of macromolecule metabolic process GO:0010604 405 0.022
appendage development GO:0048736 401 0.022
appendage morphogenesis GO:0035107 397 0.022
regulation of cellular catabolic process GO:0031329 157 0.021
Human
catabolic process GO:0009056 409 0.021
programmed cell death GO:0012501 257 0.021
eye morphogenesis GO:0048592 260 0.021
amine metabolic process GO:0009308 12 0.021
developmental growth GO:0048589 280 0.021
regulation of intracellular signal transduction GO:1902531 236 0.020
rna processing GO:0006396 147 0.020
regulation of localization GO:0032879 275 0.020
organic cyclic compound catabolic process GO:1901361 168 0.020
cellular protein catabolic process GO:0044257 83 0.020
regulation of cell cycle phase transition GO:1901987 130 0.020
Human
intracellular signal transduction GO:0035556 300 0.020
tissue morphogenesis GO:0048729 297 0.020
camera type eye development GO:0043010 4 0.020
apoptotic process GO:0006915 159 0.020
growth GO:0040007 359 0.020
single organism intracellular transport GO:1902582 207 0.020
adult behavior GO:0030534 137 0.020
positive regulation of cell communication GO:0010647 250 0.019
cell division GO:0051301 248 0.019
regulation of microtubule based process GO:0032886 49 0.019
Human
homeostatic process GO:0042592 199 0.019
cell cycle phase transition GO:0044770 140 0.019
ion transport GO:0006811 145 0.019
phagocytosis GO:0006909 215 0.019
positive regulation of biosynthetic process GO:0009891 316 0.019
positive regulation of signal transduction GO:0009967 223 0.019
carboxylic acid metabolic process GO:0019752 92 0.019
nucleoside triphosphate catabolic process GO:0009143 108 0.019
regulation of transport GO:0051049 181 0.019
cellular amine metabolic process GO:0044106 12 0.019
dna conformation change GO:0071103 105 0.019
cell death GO:0008219 279 0.019
regulation of molecular function GO:0065009 217 0.019
carbohydrate derivative metabolic process GO:1901135 217 0.019
modification dependent protein catabolic process GO:0019941 78 0.018
negative regulation of response to stimulus GO:0048585 258 0.018
vesicle mediated transport GO:0016192 381 0.018
cellular protein modification process GO:0006464 438 0.018
single organism catabolic process GO:0044712 228 0.018
positive regulation of gene expression GO:0010628 290 0.018
organelle fission GO:0048285 340 0.018
organic acid metabolic process GO:0006082 103 0.018
negative regulation of signal transduction GO:0009968 206 0.018
imaginal disc derived appendage morphogenesis GO:0035114 395 0.018
cellular response to dna damage stimulus GO:0006974 223 0.018
morphogenesis of an epithelium GO:0002009 276 0.017
kidney development GO:0001822 3 0.017
positive regulation of rna biosynthetic process GO:1902680 266 0.017
regulation of gene expression epigenetic GO:0040029 128 0.017
positive regulation of nucleic acid templated transcription GO:1903508 266 0.017
sensory organ morphogenesis GO:0090596 260 0.017
negative regulation of cell cycle process GO:0010948 109 0.017
Human
cellular amino acid metabolic process GO:0006520 61 0.017
regulation of phosphorus metabolic process GO:0051174 210 0.017
post embryonic appendage morphogenesis GO:0035120 385 0.017
macromolecular complex assembly GO:0065003 256 0.017
aromatic compound catabolic process GO:0019439 166 0.017
protein localization GO:0008104 284 0.017
positive regulation of rna metabolic process GO:0051254 271 0.017
oxoacid metabolic process GO:0043436 103 0.016
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.016
regulation of programmed cell death GO:0043067 152 0.016
vitamin biosynthetic process GO:0009110 1 0.016
cellularization GO:0007349 90 0.016
regulation of response to stress GO:0080134 200 0.016
organonitrogen compound catabolic process GO:1901565 128 0.016
positive regulation of signaling GO:0023056 243 0.016
immune response GO:0006955 246 0.016
anatomical structure homeostasis GO:0060249 97 0.016
mrna metabolic process GO:0016071 124 0.016
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.016
protein complex assembly GO:0006461 200 0.016
response to biotic stimulus GO:0009607 294 0.016
nucleotide catabolic process GO:0009166 109 0.016
regulation of cellular amino acid metabolic process GO:0006521 0 0.016
regulation of catalytic activity GO:0050790 185 0.015
imaginal disc derived wing morphogenesis GO:0007476 337 0.015
protein transport GO:0015031 155 0.015
endocytosis GO:0006897 310 0.015
response to other organism GO:0051707 293 0.015
neurological system process GO:0050877 358 0.015
transcription from rna polymerase ii promoter GO:0006366 368 0.015
transmembrane transport GO:0055085 139 0.015
cellular nitrogen compound catabolic process GO:0044270 165 0.015
negative regulation of mitotic cell cycle GO:0045930 109 0.015
Human
regulation of cellular ketone metabolic process GO:0010565 3 0.015
establishment or maintenance of cell polarity GO:0007163 167 0.015
modification dependent macromolecule catabolic process GO:0043632 79 0.015
protein catabolic process GO:0030163 101 0.015
establishment of localization in cell GO:0051649 402 0.015
cellular ketone metabolic process GO:0042180 24 0.015
glycerolipid catabolic process GO:0046503 3 0.014
wing disc morphogenesis GO:0007472 344 0.014
embryonic morphogenesis GO:0048598 206 0.014
proteasomal protein catabolic process GO:0010498 59 0.014
negative regulation of signaling GO:0023057 219 0.014
nucleoside phosphate metabolic process GO:0006753 162 0.014
organophosphate metabolic process GO:0019637 195 0.014
small gtpase mediated signal transduction GO:0007264 88 0.014
axon development GO:0061564 297 0.014
gene silencing GO:0016458 138 0.014
negative regulation of transcription dna templated GO:0045892 237 0.014
immune system process GO:0002376 347 0.014
purine ribonucleotide metabolic process GO:0009150 145 0.014
purine ribonucleoside triphosphate catabolic process GO:0009207 108 0.014
response to organic substance GO:0010033 284 0.014
cell cell signaling involved in cell fate commitment GO:0045168 210 0.014
regulation of transcription from rna polymerase ii promoter GO:0006357 378 0.014
connective tissue development GO:0061448 3 0.014
neutral lipid catabolic process GO:0046461 3 0.014
detection of stimulus involved in sensory perception GO:0050906 92 0.014
wnt signaling pathway GO:0016055 98 0.014
endomembrane system organization GO:0010256 119 0.014
mitotic cell cycle checkpoint GO:0007093 88 0.014
Human
mitotic dna integrity checkpoint GO:0044774 75 0.014
cellular macromolecule catabolic process GO:0044265 136 0.014
compound eye photoreceptor cell differentiation GO:0001751 140 0.014
cation transport GO:0006812 110 0.014
response to temperature stimulus GO:0009266 106 0.014
negative regulation of nucleic acid templated transcription GO:1903507 240 0.014
negative regulation of cellular biosynthetic process GO:0031327 277 0.014
cellular macromolecule localization GO:0070727 220 0.014
negative regulation of rna metabolic process GO:0051253 251 0.014
single organism cellular localization GO:1902580 180 0.014
aging GO:0007568 143 0.013
nucleoside phosphate catabolic process GO:1901292 110 0.013
g protein coupled receptor signaling pathway GO:0007186 136 0.013
purine ribonucleoside metabolic process GO:0046128 127 0.013
ribonucleotide metabolic process GO:0009259 145 0.013
mrna processing GO:0006397 104 0.013
axonogenesis GO:0007409 290 0.013
response to lipopolysaccharide GO:0032496 4 0.013
gtp metabolic process GO:0046039 72 0.013
regulation of response to external stimulus GO:0032101 115 0.013
epithelial cell differentiation GO:0030855 322 0.013
purine containing compound metabolic process GO:0072521 155 0.013
phosphorylation GO:0016310 294 0.013
proteolysis involved in cellular protein catabolic process GO:0051603 83 0.013
positive regulation of transcription dna templated GO:0045893 266 0.013
notch signaling pathway GO:0007219 120 0.013
epithelial cell development GO:0002064 274 0.013
cellular protein localization GO:0034613 160 0.013
regulation of hydrolase activity GO:0051336 97 0.013
purine nucleotide metabolic process GO:0006163 146 0.013
response to external biotic stimulus GO:0043207 293 0.013
ribose phosphate metabolic process GO:0019693 145 0.013
digestive tract morphogenesis GO:0048546 127 0.013
negative regulation of biosynthetic process GO:0009890 277 0.013
response to wounding GO:0009611 94 0.013
negative regulation of cellular component organization GO:0051129 108 0.013
Human
negative regulation of cell cycle phase transition GO:1901988 103 0.012
Human
mitotic sister chromatid separation GO:0051306 30 0.012
photoreceptor cell differentiation GO:0046530 170 0.012
cation transmembrane transport GO:0098655 88 0.012
membrane organization GO:0061024 112 0.012
negative regulation of developmental process GO:0051093 201 0.012
dna endoreduplication GO:0042023 22 0.012
regulation of notch signaling pathway GO:0008593 100 0.012
tube morphogenesis GO:0035239 191 0.012
regulation of phosphate metabolic process GO:0019220 210 0.012
purine ribonucleoside catabolic process GO:0046130 112 0.012
chemosensory behavior GO:0007635 106 0.012
purine containing compound catabolic process GO:0072523 112 0.012
purine nucleoside triphosphate catabolic process GO:0009146 108 0.012
enzyme linked receptor protein signaling pathway GO:0007167 179 0.012
positive regulation of catalytic activity GO:0043085 118 0.012
rna polyadenylation GO:0043631 12 0.012
positive regulation of molecular function GO:0044093 136 0.012
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.012
protein phosphorylation GO:0006468 169 0.012
mrna polyadenylation GO:0006378 11 0.012
embryonic development via the syncytial blastoderm GO:0001700 148 0.012
protein processing GO:0016485 68 0.012
defense response to gram negative bacterium GO:0050829 94 0.012
negative regulation of organelle organization GO:0010639 56 0.012
Human
eye photoreceptor cell differentiation GO:0001754 145 0.012
organonitrogen compound biosynthetic process GO:1901566 117 0.012
single organism biosynthetic process GO:0044711 206 0.012
metal ion transport GO:0030001 74 0.012
negative regulation of mitotic cell cycle phase transition GO:1901991 103 0.012
Human
chemotaxis GO:0006935 249 0.012
dorsal ventral pattern formation GO:0009953 133 0.012
dendrite development GO:0016358 204 0.012
double strand break repair GO:0006302 26 0.012
regulation of anatomical structure morphogenesis GO:0022603 242 0.012
single organism membrane organization GO:0044802 93 0.012
dna packaging GO:0006323 91 0.012
dna damage checkpoint GO:0000077 78 0.011
dna integrity checkpoint GO:0031570 81 0.011
olfactory behavior GO:0042048 97 0.011
cellular response to chemical stimulus GO:0070887 199 0.011
nucleobase containing small molecule metabolic process GO:0055086 174 0.011
positive regulation of hydrolase activity GO:0051345 78 0.011
negative regulation of cell communication GO:0010648 223 0.011
chromatin organization GO:0006325 207 0.011
forebrain development GO:0030900 2 0.011
ion transmembrane transport GO:0034220 122 0.011
regulation of defense response GO:0031347 102 0.011
columnar cuboidal epithelial cell differentiation GO:0002065 256 0.011
negative regulation of cellular protein metabolic process GO:0032269 85 0.011
Human
digestive tract development GO:0048565 149 0.011
nucleotide metabolic process GO:0009117 161 0.011
negative regulation of rna biosynthetic process GO:1902679 240 0.011
positive regulation of phosphorus metabolic process GO:0010562 139 0.011
cellular macromolecular complex assembly GO:0034622 153 0.011
ribonucleoside metabolic process GO:0009119 127 0.011
metaphase anaphase transition of cell cycle GO:0044784 28 0.011
actin filament based process GO:0030029 220 0.011
nucleoside catabolic process GO:0009164 112 0.011
ribonucleotide catabolic process GO:0009261 109 0.011
organophosphate catabolic process GO:0046434 112 0.011
negative regulation of homeostatic process GO:0032845 2 0.011
chaeta development GO:0022416 97 0.011
gland development GO:0048732 191 0.011
response to monosaccharide GO:0034284 4 0.011
purine nucleotide catabolic process GO:0006195 109 0.011
regulation of proteolysis GO:0030162 87 0.011
Human
intracellular protein transport GO:0006886 104 0.011
histolysis GO:0007559 102 0.011
regionalization GO:0003002 416 0.011
tube development GO:0035295 244 0.011
cytokinesis GO:0000910 90 0.011
nephron development GO:0072006 3 0.011
acylglycerol catabolic process GO:0046464 3 0.011
defense response to bacterium GO:0042742 178 0.011
proteasome mediated ubiquitin dependent protein catabolic process GO:0043161 54 0.011
response to oxygen containing compound GO:1901700 200 0.011
camera type eye morphogenesis GO:0048593 2 0.011
establishment of protein localization GO:0045184 163 0.011
cellular response to biotic stimulus GO:0071216 4 0.011
wound healing GO:0042060 75 0.011
regulation of apoptotic process GO:0042981 130 0.010
nucleoside metabolic process GO:0009116 127 0.010
ribonucleoside triphosphate catabolic process GO:0009203 108 0.010
positive regulation of cell migration GO:0030335 2 0.010
nuclear transport GO:0051169 72 0.010
defense response GO:0006952 300 0.010
response to light stimulus GO:0009416 124 0.010
cell migration GO:0016477 238 0.010
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.010
regulation of cell death GO:0010941 173 0.010
regulation of immune response GO:0050776 118 0.010
protein maturation GO:0051604 71 0.010
purine ribonucleotide catabolic process GO:0009154 109 0.010
regulation of mitotic metaphase anaphase transition GO:0030071 26 0.010
Human
response to bacterium GO:0009617 198 0.010
positive regulation of catabolic process GO:0009896 105 0.010
protein dna complex assembly GO:0065004 63 0.010
peptidyl amino acid modification GO:0018193 105 0.010
actin filament organization GO:0007015 126 0.010
skeletal muscle fiber development GO:0048741 3 0.010
multicellular organismal reproductive behavior GO:0033057 110 0.010

Gen disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.059
disease of metabolism DOID:0014667 0 0.017
inherited metabolic disorder DOID:655 0 0.016
nervous system disease DOID:863 0 0.015
respiratory system disease DOID:1579 0 0.014
lower respiratory tract disease DOID:0050161 0 0.014
cardiovascular system disease DOID:1287 0 0.013