Drosophila melanogaster

46 known processes

SPoCk (Dmel_CG32451)

Secretory Pathway Calcium atpase

(Aliases: anon-WO0118547.249,CG32451,CG14449,SPoCK,CG7651,Dmel\CG32451)

SPoCk biological process predictions


Filter by process size:
Biological process GO term ID Process size Probability Func Analog Org
sensory perception of salty taste GO:0050914 3 0.090
neurological system process GO:0050877 358 0.073
single organism behavior GO:0044708 391 0.063
positive regulation of macromolecule metabolic process GO:0010604 405 0.055
organonitrogen compound metabolic process GO:1901564 318 0.054
Rat
actin filament based process GO:0030029 220 0.052
sensory perception GO:0007600 196 0.051
carbohydrate derivative metabolic process GO:1901135 217 0.048
Rat
eye development GO:0001654 323 0.046
store operated calcium entry GO:0002115 3 0.044
single organism catabolic process GO:0044712 228 0.042
Rat
catabolic process GO:0009056 409 0.041
Rat
digestive tract morphogenesis GO:0048546 127 0.041
intracellular signal transduction GO:0035556 300 0.039
negative regulation of gene expression GO:0010629 387 0.039
tube development GO:0035295 244 0.038
camera type eye development GO:0043010 4 0.038
guanosine containing compound catabolic process GO:1901069 74 0.036
cellular protein modification process GO:0006464 438 0.036
regulation of cellular component biogenesis GO:0044087 201 0.036
nucleobase containing small molecule metabolic process GO:0055086 174 0.036
Rat
small molecule metabolic process GO:0044281 305 0.034
Rat
organophosphate metabolic process GO:0019637 195 0.034
Rat
single organism biosynthetic process GO:0044711 206 0.033
gene silencing GO:0016458 138 0.032
regulation of response to external stimulus GO:0032101 115 0.031
embryonic hindgut morphogenesis GO:0048619 48 0.031
nucleotide metabolic process GO:0009117 161 0.031
Rat
negative regulation of nitrogen compound metabolic process GO:0051172 265 0.030
response to organic substance GO:0010033 284 0.030
small gtpase mediated signal transduction GO:0007264 88 0.030
positive regulation of response to stimulus GO:0048584 323 0.030
regulation of gene silencing GO:0060968 63 0.030
cellular response to chemical stimulus GO:0070887 199 0.029
amine metabolic process GO:0009308 12 0.029
negative regulation of cell communication GO:0010648 223 0.029
divalent inorganic cation transport GO:0072511 30 0.029
nucleoside catabolic process GO:0009164 112 0.028
Rat
regulation of cellular amine metabolic process GO:0033238 3 0.028
negative regulation of macromolecule biosynthetic process GO:0010558 270 0.028
negative regulation of biosynthetic process GO:0009890 277 0.027
hindgut morphogenesis GO:0007442 58 0.027
cellular catabolic process GO:0044248 372 0.026
Rat
negative regulation of rna metabolic process GO:0051253 251 0.026
exocrine system development GO:0035272 162 0.025
morphogenesis of an epithelium GO:0002009 276 0.025
organonitrogen compound catabolic process GO:1901565 128 0.025
Rat
cellular amino acid metabolic process GO:0006520 61 0.025
purine containing compound metabolic process GO:0072521 155 0.025
Rat
g protein coupled receptor signaling pathway GO:0007186 136 0.025
cell motility GO:0048870 251 0.025
positive regulation of nucleobase containing compound metabolic process GO:0045935 332 0.025
cation transport GO:0006812 110 0.025
positive regulation of cell communication GO:0010647 250 0.025
salivary gland development GO:0007431 162 0.024
embryo development ending in birth or egg hatching GO:0009792 152 0.024
cellular nitrogen compound catabolic process GO:0044270 165 0.024
Rat
death GO:0016265 284 0.024
ribose phosphate metabolic process GO:0019693 145 0.023
Rat
behavioral response to ethanol GO:0048149 49 0.023
circadian behavior GO:0048512 76 0.023
salivary gland morphogenesis GO:0007435 145 0.023
embryonic morphogenesis GO:0048598 206 0.023
centrosome organization GO:0051297 163 0.023
posttranscriptional regulation of gene expression GO:0010608 145 0.023
heterocycle catabolic process GO:0046700 166 0.023
Rat
organic cyclic compound catabolic process GO:1901361 168 0.023
Rat
appendage morphogenesis GO:0035107 397 0.023
developmental growth GO:0048589 280 0.023
actin cytoskeleton organization GO:0030036 206 0.022
gland morphogenesis GO:0022612 145 0.022
sensory organ morphogenesis GO:0090596 260 0.022
malpighian tubule morphogenesis GO:0007443 44 0.022
ribonucleoside metabolic process GO:0009119 127 0.022
Rat
renal tubule development GO:0061326 64 0.022
renal tubule morphogenesis GO:0061333 44 0.022
body morphogenesis GO:0010171 2 0.021
growth GO:0040007 359 0.021
organic substance catabolic process GO:1901575 308 0.021
Rat
tube morphogenesis GO:0035239 191 0.021
response to oxygen containing compound GO:1901700 200 0.021
positive regulation of signaling GO:0023056 243 0.021
malpighian tubule development GO:0072002 64 0.021
regulation of cellular protein metabolic process GO:0032268 243 0.021
response to abiotic stimulus GO:0009628 341 0.021
carbohydrate derivative catabolic process GO:1901136 118 0.020
Rat
epithelial tube morphogenesis GO:0060562 88 0.020
regulation of response to stress GO:0080134 200 0.020
homeostatic process GO:0042592 199 0.020
protein complex biogenesis GO:0070271 201 0.020
protein complex assembly GO:0006461 200 0.020
response to biotic stimulus GO:0009607 294 0.020
positive regulation of multicellular organismal process GO:0051240 143 0.020
imaginal disc derived appendage morphogenesis GO:0035114 395 0.019
regulation of phosphorus metabolic process GO:0051174 210 0.019
regulation of mitotic cell cycle GO:0007346 190 0.019
organic acid metabolic process GO:0006082 103 0.019
eye morphogenesis GO:0048592 260 0.019
ras protein signal transduction GO:0007265 88 0.019
regulation of nucleotide metabolic process GO:0006140 62 0.019
negative regulation of signaling GO:0023057 219 0.019
regulation of molecular function GO:0065009 217 0.019
transcription from rna polymerase ii promoter GO:0006366 368 0.019
cellular amine metabolic process GO:0044106 12 0.019
positive regulation of protein metabolic process GO:0051247 128 0.019
regulation of growth GO:0040008 233 0.019
negative regulation of cellular biosynthetic process GO:0031327 277 0.019
purine nucleotide metabolic process GO:0006163 146 0.019
Rat
purine ribonucleotide catabolic process GO:0009154 109 0.018
Rat
tissue death GO:0016271 102 0.018
digestive tract development GO:0048565 149 0.018
positive regulation of nitrogen compound metabolic process GO:0051173 354 0.018
rhythmic behavior GO:0007622 76 0.018
nucleobase containing compound catabolic process GO:0034655 165 0.018
Rat
cellular ketone metabolic process GO:0042180 24 0.018
nucleoside phosphate metabolic process GO:0006753 162 0.018
Rat
positive regulation of biosynthetic process GO:0009891 316 0.018
mitotic spindle organization GO:0007052 220 0.018
macromolecular complex assembly GO:0065003 256 0.018
appendage development GO:0048736 401 0.017
regulation of multicellular organismal development GO:2000026 414 0.017
regulation of catabolic process GO:0009894 170 0.017
ribonucleotide metabolic process GO:0009259 145 0.017
Rat
regulation of organelle organization GO:0033043 196 0.017
digestive system development GO:0055123 149 0.017
cellular macromolecular complex assembly GO:0034622 153 0.017
localization of cell GO:0051674 257 0.017
phosphorylation GO:0016310 294 0.017
positive regulation of signal transduction GO:0009967 223 0.017
positive regulation of cellular biosynthetic process GO:0031328 316 0.016
regulation of cellular localization GO:0060341 136 0.016
nuclear division GO:0000280 332 0.016
regulation of phosphate metabolic process GO:0019220 210 0.016
olfactory behavior GO:0042048 97 0.016
cation transmembrane transport GO:0098655 88 0.016
Rat
compound eye development GO:0048749 307 0.016
regulation of intracellular transport GO:0032386 64 0.016
regulation of cell differentiation GO:0045595 302 0.016
regulation of immune system process GO:0002682 176 0.016
oxoacid metabolic process GO:0043436 103 0.016
response to radiation GO:0009314 155 0.016
signal transduction by phosphorylation GO:0023014 107 0.016
cellular homeostasis GO:0019725 80 0.015
regulation of developmental growth GO:0048638 174 0.015
negative regulation of rna biosynthetic process GO:1902679 240 0.015
regulation of synapse organization GO:0050807 110 0.015
muscle structure development GO:0061061 224 0.015
mapk cascade GO:0000165 107 0.015
regulation of cellular catabolic process GO:0031329 157 0.015
purine ribonucleoside catabolic process GO:0046130 112 0.015
Rat
regulation of localization GO:0032879 275 0.015
negative regulation of intracellular signal transduction GO:1902532 57 0.015
negative regulation of cellular macromolecule biosynthetic process GO:2000113 267 0.015
regulation of gene expression epigenetic GO:0040029 128 0.015
spindle organization GO:0007051 253 0.015
negative regulation of response to stimulus GO:0048585 258 0.015
ribonucleotide catabolic process GO:0009261 109 0.015
Rat
positive regulation of purine nucleotide metabolic process GO:1900544 55 0.015
compound eye morphogenesis GO:0001745 249 0.015
regulation of cellular amino acid metabolic process GO:0006521 0 0.015
negative regulation of protein metabolic process GO:0051248 85 0.015
post embryonic appendage morphogenesis GO:0035120 385 0.014
positive regulation of cell motility GO:2000147 3 0.014
developmental programmed cell death GO:0010623 138 0.014
retina development in camera type eye GO:0060041 4 0.014
programmed cell death GO:0012501 257 0.014
adult behavior GO:0030534 137 0.014
protein modification process GO:0036211 438 0.014
wing disc morphogenesis GO:0007472 344 0.014
regulation of cellular ketone metabolic process GO:0010565 3 0.014
protein phosphorylation GO:0006468 169 0.014
sensory perception of chemical stimulus GO:0007606 116 0.014
ribonucleoside catabolic process GO:0042454 112 0.014
Rat
purine containing compound catabolic process GO:0072523 112 0.014
Rat
carboxylic acid metabolic process GO:0019752 92 0.014
gene silencing by rna GO:0031047 57 0.014
response to external biotic stimulus GO:0043207 293 0.014
positive regulation of transcription dna templated GO:0045893 266 0.014
stem cell differentiation GO:0048863 117 0.014
purine nucleoside metabolic process GO:0042278 127 0.014
Rat
proteolysis GO:0006508 192 0.014
tissue morphogenesis GO:0048729 297 0.014
salt aversion GO:0035199 3 0.014
nucleoside triphosphate metabolic process GO:0009141 120 0.014
Rat
renal system development GO:0072001 72 0.014
negative regulation of cell death GO:0060548 81 0.014
central nervous system development GO:0007417 201 0.014
histolysis GO:0007559 102 0.013
negative regulation of transcription dna templated GO:0045892 237 0.013
cellular response to dna damage stimulus GO:0006974 223 0.013
positive regulation of macromolecule biosynthetic process GO:0010557 283 0.013
gtp catabolic process GO:0006184 72 0.013
regulation of nucleoside metabolic process GO:0009118 50 0.013
divalent metal ion transport GO:0070838 26 0.013
autophagic cell death GO:0048102 83 0.013
male courtship behavior veined wing vibration GO:0016545 21 0.013
response to alcohol GO:0097305 95 0.013
glycosyl compound catabolic process GO:1901658 112 0.013
Rat
salivary gland cell autophagic cell death GO:0035071 83 0.013
detection of stimulus involved in sensory perception GO:0050906 92 0.013
forebrain development GO:0030900 2 0.013
ribonucleoside triphosphate catabolic process GO:0009203 108 0.013
Rat
negative regulation of cellular protein metabolic process GO:0032269 85 0.013
defense response to other organism GO:0098542 225 0.013
cellular ion homeostasis GO:0006873 39 0.013
gland development GO:0048732 191 0.012
negative regulation of mitotic cell cycle GO:0045930 109 0.012
actin filament based movement GO:0030048 26 0.012
positive regulation of rna biosynthetic process GO:1902680 266 0.012
glycosyl compound metabolic process GO:1901657 127 0.012
Rat
microtubule polymerization or depolymerization GO:0031109 39 0.012
epithelial cell differentiation GO:0030855 322 0.012
response to hypoxia GO:0001666 53 0.012
positive regulation of catabolic process GO:0009896 105 0.012
purine ribonucleotide metabolic process GO:0009150 145 0.012
Rat
synaptic growth at neuromuscular junction GO:0051124 119 0.012
nucleoside metabolic process GO:0009116 127 0.012
Rat
dna metabolic process GO:0006259 227 0.012
purine nucleoside triphosphate metabolic process GO:0009144 119 0.012
Rat
negative regulation of cellular component organization GO:0051129 108 0.012
endomembrane system organization GO:0010256 119 0.012
purine ribonucleoside metabolic process GO:0046128 127 0.012
Rat
gtp metabolic process GO:0046039 72 0.012
guanosine containing compound metabolic process GO:1901068 74 0.012
chromosome organization GO:0051276 360 0.012
circulatory system process GO:0003013 37 0.012
hindgut development GO:0061525 58 0.012
response to extracellular stimulus GO:0009991 116 0.012
regulation of gtpase activity GO:0043087 44 0.011
urogenital system development GO:0001655 72 0.011
regulation of phosphorylation GO:0042325 147 0.011
organic hydroxy compound metabolic process GO:1901615 83 0.011
positive regulation of cellular catabolic process GO:0031331 95 0.011
protein localization GO:0008104 284 0.011
ion transport GO:0006811 145 0.011
purine nucleoside triphosphate catabolic process GO:0009146 108 0.011
Rat
regulation of intracellular signal transduction GO:1902531 236 0.011
ribonucleoside triphosphate metabolic process GO:0009199 119 0.011
Rat
regulation of gtp catabolic process GO:0033124 44 0.011
long term memory GO:0007616 62 0.011
defense response GO:0006952 300 0.011
regulation of ras protein signal transduction GO:0046578 93 0.011
negative regulation of signal transduction GO:0009968 206 0.011
negative regulation of nucleic acid templated transcription GO:1903507 240 0.011
apoptotic process GO:0006915 159 0.011
histone modification GO:0016570 106 0.011
telencephalon development GO:0021537 2 0.011
regulation of hydrolase activity GO:0051336 97 0.011
vesicle organization GO:0016050 44 0.010
positive regulation of gene expression GO:0010628 290 0.010
response to oxygen levels GO:0070482 59 0.010
endocytosis GO:0006897 310 0.010
membrane organization GO:0061024 112 0.010
mesenchymal cell development GO:0014031 1 0.010
eye antennal disc morphogenesis GO:0007455 34 0.010
organic substance transport GO:0071702 257 0.010
positive regulation of molecular function GO:0044093 136 0.010
covalent chromatin modification GO:0016569 106 0.010
negative regulation of nucleobase containing compound metabolic process GO:0045934 261 0.010
cognition GO:0050890 141 0.010
organophosphate catabolic process GO:0046434 112 0.010
Rat
response to decreased oxygen levels GO:0036293 58 0.010
synaptic target recognition GO:0008039 45 0.010
cell division GO:0051301 248 0.010
hindbrain development GO:0030902 2 0.010
establishment of localization in cell GO:0051649 402 0.010
imaginal disc derived appendage development GO:0048737 399 0.010
macromolecule catabolic process GO:0009057 161 0.010

SPoCk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease DO term ID Size Probability Func Analog Org
disease of anatomical entity DOID:7 0 0.072
cardiovascular system disease DOID:1287 0 0.030
nervous system disease DOID:863 0 0.024
sensory system disease DOID:0050155 0 0.019
eye and adnexa disease DOID:1492 0 0.019
eye disease DOID:5614 0 0.019
musculoskeletal system disease DOID:17 0 0.013
central nervous system disease DOID:331 0 0.010